Click here to switch to the map view.

The map label for this gene is engA

Identifier: 32267038

GI number: 32267038

Start: 1475123

End: 1476586

Strand: Direct

Name: engA

Synonym: HH1539

Alternate gene names: 32267038

Gene position: 1475123-1476586 (Clockwise)

Preceding gene: 32267037

Following gene: 32267040

Centisome position: 81.99

GC content: 37.02

Gene sequence:

>1464_bases
ATGAAAACAATTGCAATTTTGGGCAAACCCAATGTAGGCAAAAGCTCCCTTTTTAATCGACTTATCAAGCAACATTTAGC
TATCACTTCAGATGTAAGTGGGACAACGCGTGATGTAAAAAGAGCGTGTTTTGATATAAGTGGCGTAGAAGTAGAACTAC
TTGATACAGGTGGAATTGATAAGGCAGAGGGTTTATTTGCCAAAGTATCTGCCAATTCGCTAAAAGCAGGGCAAGAGGCA
GATTTGGTTTTATATATGGTTGATGGGAATGTTGTGCCTCAAGATGATGATATTGCATATTTTCGCACAATTCAAAAGGC
TAAAAAACCGCTTGTGCTTGTTATCAATAAGGTTGATAATGATAAAATCAAGCAACAAGCGTGGGATTTTGCGTGTTTTG
GTGCAGAACAGATGTATTTTATTTCTGTGCATCACAATCGTGGGTTAAGTATTTTGCTTGAAGCTATTTTTGAACTCCTC
TCTCTTGCAAAGGAGCAATCTTTAAGTAATAATTTGCGCTCACAAATGGATAACGAAGAGATTGATGAGAGTTTAGAGGA
GTTTTTGGGTATTTTAGAATCTACTCCAAATAAGAGTGAGGAAAACATTGCTGTTGGGATTATTGGACGCGTAAATGTAG
GCAAAAGCTCCCTCTTAAATGCACTTTTGGGTAAAGAGAGAAGTGTAGTAAGTGAAGTGGCTGGAACGACTATTGATCCT
GTAGATGATGAAATGGATATAGAGGGCAAAAGAGTAAGATTTGTGGATACGGCAGGGATTAGACGCGCGAGTAAGATTTG
GGGGATTGAAAAATTTGCACTTTTACGCACAAATGCAGCACTTGCCCAAAGTCATATTGTGATTTTAGTTCTTGATGCGA
GCGAAAGTTTTGTTGAATTAGATGAAAAAATTAGCTCTCTTATTCCTAAACACGCTTTGGGAGTGATTGTTGTGCTAAAT
AAATGGGACAAAAAGCATAAGGAATATAAAGAAATCATCAAAGAATTTAAGCATAGATTCCCATTTCTTTCTTTCGCTCC
AGTGATGACATTGAGTGCTCTTAATGGGCGTAATATTGATAAACTTAAAAAGGAAATTTTGAAGGTTTATCAGCGTTTTG
CATATAGAATCCCTACAAGTGCGCTTAATGATGTTATCGCTCAAGCAGTAGCACATCATCATATTCCAAGCGATCACGGC
AAGATTGTCAAAATTTATTATGCTACGCAATATGCCACACATCCGCCACAAATTGCGCTTGTGAGCAATCGCCCAGAAAG
TTTGCATTTTAGCTACAAGCGATATATTATCAATATGTTAAGGGAGCAATTTGATTTTGAAGGTGTGCCAATTTTATTAA
GTGTAAAGGGCAAAAATGCCAAAGATGAGGAAAATACATCTGCAAAAAAAGAATCTCCAAGTAAAGTATCGCATAGAGAA
TCTAAAAATCGCAGATTTGTATAA

Upstream 100 bases:

>100_bases
CGAAATTATCAAAAAGTTATTTTATCAATCTAAAATCCAACTTTAATCCAACTTTGGCTAAGATGTCTTGTAAAAATATT
TTATCAAATAGAGAATCTCA

Downstream 100 bases:

>100_bases
GAAATTTCTATAATTTATTTTATACCACAAAAATCTTTAATTGCTTCAACTTTATCTGTTTTTTCCCAGCTAAATTCGTT
TAATTCGCGTCCAAAATGTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MKTIAILGKPNVGKSSLFNRLIKQHLAITSDVSGTTRDVKRACFDISGVEVELLDTGGIDKAEGLFAKVSANSLKAGQEA
DLVLYMVDGNVVPQDDDIAYFRTIQKAKKPLVLVINKVDNDKIKQQAWDFACFGAEQMYFISVHHNRGLSILLEAIFELL
SLAKEQSLSNNLRSQMDNEEIDESLEEFLGILESTPNKSEENIAVGIIGRVNVGKSSLLNALLGKERSVVSEVAGTTIDP
VDDEMDIEGKRVRFVDTAGIRRASKIWGIEKFALLRTNAALAQSHIVILVLDASESFVELDEKISSLIPKHALGVIVVLN
KWDKKHKEYKEIIKEFKHRFPFLSFAPVMTLSALNGRNIDKLKKEILKVYQRFAYRIPTSALNDVIAQAVAHHHIPSDHG
KIVKIYYATQYATHPPQIALVSNRPESLHFSYKRYIINMLREQFDFEGVPILLSVKGKNAKDEENTSAKKESPSKVSHRE
SKNRRFV

Sequences:

>Translated_487_residues
MKTIAILGKPNVGKSSLFNRLIKQHLAITSDVSGTTRDVKRACFDISGVEVELLDTGGIDKAEGLFAKVSANSLKAGQEA
DLVLYMVDGNVVPQDDDIAYFRTIQKAKKPLVLVINKVDNDKIKQQAWDFACFGAEQMYFISVHHNRGLSILLEAIFELL
SLAKEQSLSNNLRSQMDNEEIDESLEEFLGILESTPNKSEENIAVGIIGRVNVGKSSLLNALLGKERSVVSEVAGTTIDP
VDDEMDIEGKRVRFVDTAGIRRASKIWGIEKFALLRTNAALAQSHIVILVLDASESFVELDEKISSLIPKHALGVIVVLN
KWDKKHKEYKEIIKEFKHRFPFLSFAPVMTLSALNGRNIDKLKKEILKVYQRFAYRIPTSALNDVIAQAVAHHHIPSDHG
KIVKIYYATQYATHPPQIALVSNRPESLHFSYKRYIINMLREQFDFEGVPILLSVKGKNAKDEENTSAKKESPSKVSHRE
SKNRRFV
>Mature_487_residues
MKTIAILGKPNVGKSSLFNRLIKQHLAITSDVSGTTRDVKRACFDISGVEVELLDTGGIDKAEGLFAKVSANSLKAGQEA
DLVLYMVDGNVVPQDDDIAYFRTIQKAKKPLVLVINKVDNDKIKQQAWDFACFGAEQMYFISVHHNRGLSILLEAIFELL
SLAKEQSLSNNLRSQMDNEEIDESLEEFLGILESTPNKSEENIAVGIIGRVNVGKSSLLNALLGKERSVVSEVAGTTIDP
VDDEMDIEGKRVRFVDTAGIRRASKIWGIEKFALLRTNAALAQSHIVILVLDASESFVELDEKISSLIPKHALGVIVVLN
KWDKKHKEYKEIIKEFKHRFPFLSFAPVMTLSALNGRNIDKLKKEILKVYQRFAYRIPTSALNDVIAQAVAHHHIPSDHG
KIVKIYYATQYATHPPQIALVSNRPESLHFSYKRYIINMLREQFDFEGVPILLSVKGKNAKDEENTSAKKESPSKVSHRE
SKNRRFV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=494, Percent_Identity=34.8178137651822, Blast_Score=264, Evalue=9e-72,
Organism=Escherichia coli, GI1788919, Length=201, Percent_Identity=29.8507462686567, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367268, Length=122, Percent_Identity=38.5245901639344, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=167, Percent_Identity=29.940119760479, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_HELHP (Q7VFY6)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_861070.1
- ProteinModelPortal:   Q7VFY6
- SMR:   Q7VFY6
- GeneID:   1492086
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1539
- NMPDR:   fig|235279.1.peg.1539
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   HHEP235279:HH_1539-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54563; Mature: 54563

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIAILGKPNVGKSSLFNRLIKQHLAITSDVSGTTRDVKRACFDISGVEVELLDTGGID
CCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
KAEGLFAKVSANSLKAGQEADLVLYMVDGNVVPQDDDIAYFRTIQKAKKPLVLVINKVDN
CCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
DKIKQQAWDFACFGAEQMYFISVHHNRGLSILLEAIFELLSLAKEQSLSNNLRSQMDNEE
HHHHHHHHCCEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IDESLEEFLGILESTPNKSEENIAVGIIGRVNVGKSSLLNALLGKERSVVSEVAGTTIDP
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCCCC
VDDEMDIEGKRVRFVDTAGIRRASKIWGIEKFALLRTNAALAQSHIVILVLDASESFVEL
CCCCCCCCCCEEEEEECCCCHHHHHHHCHHHHHHHHCCHHHHCCCEEEEEECCCCHHHHH
DEKISSLIPKHALGVIVVLNKWDKKHKEYKEIIKEFKHRFPFLSFAPVMTLSALNGRNID
HHHHHHHCCHHHCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
KLKKEILKVYQRFAYRIPTSALNDVIAQAVAHHHIPSDHGKIVKIYYATQYATHPPQIAL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCEEE
VSNRPESLHFSYKRYIINMLREQFDFEGVPILLSVKGKNAKDEENTSAKKESPSKVSHRE
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
SKNRRFV
CCCCCCC
>Mature Secondary Structure
MKTIAILGKPNVGKSSLFNRLIKQHLAITSDVSGTTRDVKRACFDISGVEVELLDTGGID
CCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
KAEGLFAKVSANSLKAGQEADLVLYMVDGNVVPQDDDIAYFRTIQKAKKPLVLVINKVDN
CCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
DKIKQQAWDFACFGAEQMYFISVHHNRGLSILLEAIFELLSLAKEQSLSNNLRSQMDNEE
HHHHHHHHCCEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IDESLEEFLGILESTPNKSEENIAVGIIGRVNVGKSSLLNALLGKERSVVSEVAGTTIDP
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCCCC
VDDEMDIEGKRVRFVDTAGIRRASKIWGIEKFALLRTNAALAQSHIVILVLDASESFVEL
CCCCCCCCCCEEEEEECCCCHHHHHHHCHHHHHHHHCCHHHHCCCEEEEEECCCCHHHHH
DEKISSLIPKHALGVIVVLNKWDKKHKEYKEIIKEFKHRFPFLSFAPVMTLSALNGRNID
HHHHHHHCCHHHCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
KLKKEILKVYQRFAYRIPTSALNDVIAQAVAHHHIPSDHGKIVKIYYATQYATHPPQIAL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCEEE
VSNRPESLHFSYKRYIINMLREQFDFEGVPILLSVKGKNAKDEENTSAKKESPSKVSHRE
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
SKNRRFV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12810954