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The map label for this gene is cysC

Identifier: 32266937

GI number: 32266937

Start: 1383594

End: 1384199

Strand: Direct

Name: cysC

Synonym: HH1438

Alternate gene names: 32266937

Gene position: 1383594-1384199 (Clockwise)

Preceding gene: 32266936

Following gene: 32266938

Centisome position: 76.9

GC content: 35.97

Gene sequence:

>606_bases
ATGCAAAATCAATCCATACAATCAAAACAAACTTCACAACAAGACAATCAACAAACAAGCACAATGTGTTCAAAGCAACA
AGGCGCAGTTATTTGGATTTGTGGATTGGCAGGAGCAGGGAAAACGACTATTGCCAAAGAAATTTTTACGCTTTTAGAGC
AAAAATACTCTAATGTAATATTTTTAGATGGCGATGAGTTTAGAGAGATTTTTGGACGCAGTGGCTTTAGCAAAGAGGAG
CGCTTAGAAGTCGCAAGATTGATTGCAAAATTATGTGTTTTTCTCTCAAAGAGTGGTTTAATCGTAGTGTGCGCAACCAT
TTCGCTTTTTGATGAGATTTATGCTTTCAATCGCTCGCATATCGCGCGTTATTTTGAAGTTTTTGTAGAGTGTTCTATGG
AGGAGTTATTAAGACGAGATAAAAAAGCCTTGTATTCTCAAGCTCTCAAGGGAGATATAAAAGATGTTATAGGCATAGAT
TTAACCTATGATACGCCTAAAGCGCATTATGTGCTTCAAAACAACACCGCCGATAAGTTAGATTCTAAAGTGAAGGAACT
TTATAACGCAGTAGAAAAGTTTTTAATACAAAAAGGAGCAAAATAA

Upstream 100 bases:

>100_bases
TTGCGATGATGTGGCATATTGAACGCGCTCCAAAAATGGGAGAAAATATATTATTTAATCAATGGAAAATTGGGGTAGAA
TCTCAATCAAAGGAGTAGCT

Downstream 100 bases:

>100_bases
TGAAAGCAATTATTCTAGCGGCGGGATTTGGTTCAAGGCTAATGCCTTTGACACAAGAGAATCCAAAGTGTATGGTGGAA
TATCACGGCAAAAAGCTCAT

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MQNQSIQSKQTSQQDNQQTSTMCSKQQGAVIWICGLAGAGKTTIAKEIFTLLEQKYSNVIFLDGDEFREIFGRSGFSKEE
RLEVARLIAKLCVFLSKSGLIVVCATISLFDEIYAFNRSHIARYFEVFVECSMEELLRRDKKALYSQALKGDIKDVIGID
LTYDTPKAHYVLQNNTADKLDSKVKELYNAVEKFLIQKGAK

Sequences:

>Translated_201_residues
MQNQSIQSKQTSQQDNQQTSTMCSKQQGAVIWICGLAGAGKTTIAKEIFTLLEQKYSNVIFLDGDEFREIFGRSGFSKEE
RLEVARLIAKLCVFLSKSGLIVVCATISLFDEIYAFNRSHIARYFEVFVECSMEELLRRDKKALYSQALKGDIKDVIGID
LTYDTPKAHYVLQNNTADKLDSKVKELYNAVEKFLIQKGAK
>Mature_201_residues
MQNQSIQSKQTSQQDNQQTSTMCSKQQGAVIWICGLAGAGKTTIAKEIFTLLEQKYSNVIFLDGDEFREIFGRSGFSKEE
RLEVARLIAKLCVFLSKSGLIVVCATISLFDEIYAFNRSHIARYFEVFVECSMEELLRRDKKALYSQALKGDIKDVIGID
LTYDTPKAHYVLQNNTADKLDSKVKELYNAVEKFLIQKGAK

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=185, Percent_Identity=30.8108108108108, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI62912492, Length=182, Percent_Identity=33.5164835164835, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI34447231, Length=182, Percent_Identity=33.5164835164835, Blast_Score=84, Evalue=8e-17,
Organism=Escherichia coli, GI1789107, Length=154, Percent_Identity=30.5194805194805, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17542422, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322852, Length=151, Percent_Identity=35.7615894039735, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI116007838, Length=196, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667044, Length=196, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667040, Length=196, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667032, Length=196, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24667028, Length=196, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24667036, Length=196, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22758; Mature: 22758

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNQSIQSKQTSQQDNQQTSTMCSKQQGAVIWICGLAGAGKTTIAKEIFTLLEQKYSNVI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEE
FLDGDEFREIFGRSGFSKEERLEVARLIAKLCVFLSKSGLIVVCATISLFDEIYAFNRSH
EECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
IARYFEVFVECSMEELLRRDKKALYSQALKGDIKDVIGIDLTYDTPKAHYVLQNNTADKL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCHHHH
DSKVKELYNAVEKFLIQKGAK
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNQSIQSKQTSQQDNQQTSTMCSKQQGAVIWICGLAGAGKTTIAKEIFTLLEQKYSNVI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEE
FLDGDEFREIFGRSGFSKEERLEVARLIAKLCVFLSKSGLIVVCATISLFDEIYAFNRSH
EECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
IARYFEVFVECSMEELLRRDKKALYSQALKGDIKDVIGIDLTYDTPKAHYVLQNNTADKL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCHHHH
DSKVKELYNAVEKFLIQKGAK
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]