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The map label for this gene is hsdM [C]

Identifier: 32266922

GI number: 32266922

Start: 1365552

End: 1366979

Strand: Direct

Name: hsdM [C]

Synonym: HH1423

Alternate gene names: 32266922

Gene position: 1365552-1366979 (Clockwise)

Preceding gene: 32266921

Following gene: 32266923

Centisome position: 75.9

GC content: 44.75

Gene sequence:

>1428_bases
ATGAGTGAAAAAGCGATTGTTGCAAAGGTGTGGAATTTCGCAACGATTTTGCGTGATAGTGGTGTGAGTTATACCGAGTA
TGTCGCGCAGTTAAGCTATTTGCTGTTTTTGAAAATGGAAAGTGAGCGGGAGAGTATCGGGGAGCATAGCAAAATCCCTA
CAAGCTGCAAATGGGAGCGGCTTATAAACCTAGATGGGCTGGAGCTAGAGAGTGCGTATAATGCCGCGTTAGCGCAACTT
GCAAAGAGTGAGGGCGTGATAGGGCTTGTCTATAATGATGCGCAAAACAAAATCAAAGAACCCGCGAATCTCAAAAAGCT
TTTTGTGCTTATGGATAGTGAGACTTGGCTAGGCTTGAATGTAGATGTCAAAGGCGCGATTTATGAGGGGCTGCTTGCGA
AAAACGCCACAGAGACAAAGGCGGGAGCAGGGCAGTATTTCACACCTCGCGTGCTGATAGATTCTATTGTGGGGCTAATG
GAGCTAAAGCCCAATATGGAGGTGTGCGACCCTGCGTGTGGGACGGGTGGATTTTTGCTAAGTGCGTATGAGGCGATGAA
AGCACAGACGAAAGACAAAGAGGAGATCAAATGCTTAAGAAATGAGAGGCTTTGTGGCAAGGACATCACGCCCTTAGTGG
CGTCTTTGTGCGCTATGAATCTGTATCTGCACGGAATTGGGGGCGAGGGAGGCATTATAGAAATCGGGGATTCTCTAAGT
GAGTTAGGCAATCGGCGGTTTGATAGGGTGCTAACCAATCCGCCCTTTGGCAAGAAATCGGCAACTAAGATTCTAGCCGA
AAATGGCAAGGTGAAAAGCCAAAAGGACGAATACAACAGAGAGGATTTTTTCGCCACAACCTCTAATAAGCAGCTAAATT
TCTTGCAACACATTATGAATCTTTTAAAAATCGGGGGTAAGGCTGCGGTGGTGCTACCCGATAATGTGCTGTTTGAAGCG
GGAGCTGGCGAAAAGGTGCGTAAAAAACTTTTAGAGGATTTCAATCTGCATACGATTTTGAGACTGCCCACAGGGATTTT
TTACGCACAAGGGGTGAAAGCAAATGTGCTGTTTTTTGACAAAGTGGCAACAAGCGAGGATTCCACGCAAAAAGTGTGGG
TGTATGATATGCGCACGAATATGAATCTAAGCCTTGTAACAAGTCCTTTAAGTGCGGAGCATTTAAGGGAGTTTGAATCT
TGTTTTTGCGTGGGGGCAATGGAAAATCGCAAGGAGAGTGAGCGATTTCGCTCGTTTAGCATTGGGGAGATTAAGAAGCG
CGATAAAATGAATTTGGATATTTTTTGGCTAAAAGATGAGAGTTTAGAGGATTTGGAGAATCTACCAAGCCCAAAAGATT
TAAGTGAGCAAATTTGTATAAGTCTTAAGAATGCGCTTAGGGAAATAGAGCAGTTGAAGCTAAGTTAA

Upstream 100 bases:

>100_bases
TGATTTTTAACAGAATTGGAAATTGTGTTAAAAAAATGAGAGAAAATTAACATATTGTGGAAATAGGTTGAAACTTTTAA
AATAATACAAAGGGGTAAAA

Downstream 100 bases:

>100_bases
TCTTAACTCTTCTTAATACCCTCTATGTTAGAATCTCGCAAAAATTGCAAATCAAAGCAGGTATGAACGAGGTAGCCTTT
TATGGATTTTATGGCTTTTA

Product: type I restriction-modification system

Products: NA

Alternate protein names: M.BthVORF4518P [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSEKAIVAKVWNFATILRDSGVSYTEYVAQLSYLLFLKMESERESIGEHSKIPTSCKWERLINLDGLELESAYNAALAQL
AKSEGVIGLVYNDAQNKIKEPANLKKLFVLMDSETWLGLNVDVKGAIYEGLLAKNATETKAGAGQYFTPRVLIDSIVGLM
ELKPNMEVCDPACGTGGFLLSAYEAMKAQTKDKEEIKCLRNERLCGKDITPLVASLCAMNLYLHGIGGEGGIIEIGDSLS
ELGNRRFDRVLTNPPFGKKSATKILAENGKVKSQKDEYNREDFFATTSNKQLNFLQHIMNLLKIGGKAAVVLPDNVLFEA
GAGEKVRKKLLEDFNLHTILRLPTGIFYAQGVKANVLFFDKVATSEDSTQKVWVYDMRTNMNLSLVTSPLSAEHLREFES
CFCVGAMENRKESERFRSFSIGEIKKRDKMNLDIFWLKDESLEDLENLPSPKDLSEQICISLKNALREIEQLKLS

Sequences:

>Translated_475_residues
MSEKAIVAKVWNFATILRDSGVSYTEYVAQLSYLLFLKMESERESIGEHSKIPTSCKWERLINLDGLELESAYNAALAQL
AKSEGVIGLVYNDAQNKIKEPANLKKLFVLMDSETWLGLNVDVKGAIYEGLLAKNATETKAGAGQYFTPRVLIDSIVGLM
ELKPNMEVCDPACGTGGFLLSAYEAMKAQTKDKEEIKCLRNERLCGKDITPLVASLCAMNLYLHGIGGEGGIIEIGDSLS
ELGNRRFDRVLTNPPFGKKSATKILAENGKVKSQKDEYNREDFFATTSNKQLNFLQHIMNLLKIGGKAAVVLPDNVLFEA
GAGEKVRKKLLEDFNLHTILRLPTGIFYAQGVKANVLFFDKVATSEDSTQKVWVYDMRTNMNLSLVTSPLSAEHLREFES
CFCVGAMENRKESERFRSFSIGEIKKRDKMNLDIFWLKDESLEDLENLPSPKDLSEQICISLKNALREIEQLKLS
>Mature_474_residues
SEKAIVAKVWNFATILRDSGVSYTEYVAQLSYLLFLKMESERESIGEHSKIPTSCKWERLINLDGLELESAYNAALAQLA
KSEGVIGLVYNDAQNKIKEPANLKKLFVLMDSETWLGLNVDVKGAIYEGLLAKNATETKAGAGQYFTPRVLIDSIVGLME
LKPNMEVCDPACGTGGFLLSAYEAMKAQTKDKEEIKCLRNERLCGKDITPLVASLCAMNLYLHGIGGEGGIIEIGDSLSE
LGNRRFDRVLTNPPFGKKSATKILAENGKVKSQKDEYNREDFFATTSNKQLNFLQHIMNLLKIGGKAAVVLPDNVLFEAG
AGEKVRKKLLEDFNLHTILRLPTGIFYAQGVKANVLFFDKVATSEDSTQKVWVYDMRTNMNLSLVTSPLSAEHLREFESC
FCVGAMENRKESERFRSFSIGEIKKRDKMNLDIFWLKDESLEDLENLPSPKDLSEQICISLKNALREIEQLKLS

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=520, Percent_Identity=38.2692307692308, Blast_Score=313, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 53102; Mature: 52971

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKAIVAKVWNFATILRDSGVSYTEYVAQLSYLLFLKMESERESIGEHSKIPTSCKWER
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCHHHHCCCCCCCCCCCCHHH
LINLDGLELESAYNAALAQLAKSEGVIGLVYNDAQNKIKEPANLKKLFVLMDSETWLGLN
HCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCEEEEEEEECCCEEEEE
VDVKGAIYEGLLAKNATETKAGAGQYFTPRVLIDSIVGLMELKPNMEVCDPACGTGGFLL
EEECHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
SAYEAMKAQTKDKEEIKCLRNERLCGKDITPLVASLCAMNLYLHGIGGEGGIIEIGDSLS
HHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEECHHHH
ELGNRRFDRVLTNPPFGKKSATKILAENGKVKSQKDEYNREDFFATTSNKQLNFLQHIMN
HHCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHH
LLKIGGKAAVVLPDNVLFEAGAGEKVRKKLLEDFNLHTILRLPTGIFYAQGVKANVLFFD
HHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHCCCEEEEECCCCCEEECCCEEEEEEEE
KVATSEDSTQKVWVYDMRTNMNLSLVTSPLSAEHLREFESCFCVGAMENRKESERFRSFS
EECCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHEEECCHHCCHHHHHHHCCC
IGEIKKRDKMNLDIFWLKDESLEDLENLPSPKDLSEQICISLKNALREIEQLKLS
CHHHHHCCCCCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKAIVAKVWNFATILRDSGVSYTEYVAQLSYLLFLKMESERESIGEHSKIPTSCKWER
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCHHHHCCCCCCCCCCCCHHH
LINLDGLELESAYNAALAQLAKSEGVIGLVYNDAQNKIKEPANLKKLFVLMDSETWLGLN
HCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCEEEEEEEECCCEEEEE
VDVKGAIYEGLLAKNATETKAGAGQYFTPRVLIDSIVGLMELKPNMEVCDPACGTGGFLL
EEECHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
SAYEAMKAQTKDKEEIKCLRNERLCGKDITPLVASLCAMNLYLHGIGGEGGIIEIGDSLS
HHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEECHHHH
ELGNRRFDRVLTNPPFGKKSATKILAENGKVKSQKDEYNREDFFATTSNKQLNFLQHIMN
HHCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHH
LLKIGGKAAVVLPDNVLFEAGAGEKVRKKLLEDFNLHTILRLPTGIFYAQGVKANVLFFD
HHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHCCCEEEEECCCCCEEECCCEEEEEEEE
KVATSEDSTQKVWVYDMRTNMNLSLVTSPLSAEHLREFESCFCVGAMENRKESERFRSFS
EECCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHEEECCHHCCHHHHHHHCCC
IGEIKKRDKMNLDIFWLKDESLEDLENLPSPKDLSEQICISLKNALREIEQLKLS
CHHHHHCCCCCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]