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The map label for this gene is map

Identifier: 32266897

GI number: 32266897

Start: 1339633

End: 1340391

Strand: Direct

Name: map

Synonym: HH1398

Alternate gene names: 32266897

Gene position: 1339633-1340391 (Clockwise)

Preceding gene: 32266896

Following gene: 32266898

Centisome position: 74.46

GC content: 37.29

Gene sequence:

>759_bases
ATGGCGATAGGTATTAAAAGTAAGAAAGATATAGAATCTTTGCGCATACCTAATAAGATTGTTGCTCAAACACTTGAACT
TCTACGTCTTGAAGCAAAAGAGGGCATAAGTCTTCTTGAGCTTGATAGAAAAGCAAAAGATTTTATTATCTCGCAAGGAG
GGAGACCTTCATTTTATCAGTTGTATGGTTTTCCGCAATCAATTTGTATTTCTGTGAATCAAGTGATTATTCACGGAATC
CCCACAGATTATATACTCAAAAATGGTGATATTGTAGGGATTGATATAGGAGTGGAATATAATGGCTGGTATGGCGATGC
TGCAATTACTATTGGGATTGGCGATATTCAAGAGACAGATAGAATCTTGATTGATTGTGCTAAGGATACTTTATATGAGG
CTATTTCTAAAGTCAAAATAGGTATGCGCTTTAAGGAATTAAGCCTCATTCTAGAACAAGCGATTAATGGGCGTGGATTC
GTTCCATTGCGTGGATTTTGTGGGCACGGAATCGGGCGAAGTCCGCACGAAGAGCCAGAGATTCCAAATTATTTAGAATC
TCCTCATACAAATCAAGGACCAAAAATTAAAGAAGGTATGGTGTTTTGTTTAGAGCCAATGATTGCTCAACATAATGGGG
AGCCTGTGATTTTAAATGATAATTGGTCGGTAATAGCCAAAGATGGTTTAAATGGTAGCCATTATGAACATACGATTGCA
ATTGTTGATGGCAAAGCAGAGATTTTAACGGAGGTATAA

Upstream 100 bases:

>100_bases
GTATTAATTGTCGTGCAAGTCGCTATTGATACGATGAGACGCATAGAAGCCCAAATTTATATGAGTAAATATCAGACCCT
AAGCGCCGTAGGGCTCTAAT

Downstream 100 bases:

>100_bases
GAATGGCAAAAGATGATGTGATTGAAGTTGATGGCAAAGTTATTGAAGCTTTGCCAAATGCGACTTTTCGCGTGCAGCTT
GAAAATGGGCATATAGTGTT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MAIGIKSKKDIESLRIPNKIVAQTLELLRLEAKEGISLLELDRKAKDFIISQGGRPSFYQLYGFPQSICISVNQVIIHGI
PTDYILKNGDIVGIDIGVEYNGWYGDAAITIGIGDIQETDRILIDCAKDTLYEAISKVKIGMRFKELSLILEQAINGRGF
VPLRGFCGHGIGRSPHEEPEIPNYLESPHTNQGPKIKEGMVFCLEPMIAQHNGEPVILNDNWSVIAKDGLNGSHYEHTIA
IVDGKAEILTEV

Sequences:

>Translated_252_residues
MAIGIKSKKDIESLRIPNKIVAQTLELLRLEAKEGISLLELDRKAKDFIISQGGRPSFYQLYGFPQSICISVNQVIIHGI
PTDYILKNGDIVGIDIGVEYNGWYGDAAITIGIGDIQETDRILIDCAKDTLYEAISKVKIGMRFKELSLILEQAINGRGF
VPLRGFCGHGIGRSPHEEPEIPNYLESPHTNQGPKIKEGMVFCLEPMIAQHNGEPVILNDNWSVIAKDGLNGSHYEHTIA
IVDGKAEILTEV
>Mature_251_residues
AIGIKSKKDIESLRIPNKIVAQTLELLRLEAKEGISLLELDRKAKDFIISQGGRPSFYQLYGFPQSICISVNQVIIHGIP
TDYILKNGDIVGIDIGVEYNGWYGDAAITIGIGDIQETDRILIDCAKDTLYEAISKVKIGMRFKELSLILEQAINGRGFV
PLRGFCGHGIGRSPHEEPEIPNYLESPHTNQGPKIKEGMVFCLEPMIAQHNGEPVILNDNWSVIAKDGLNGSHYEHTIAI
VDGKAEILTEV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=34.136546184739, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI40385867, Length=251, Percent_Identity=32.6693227091633, Blast_Score=145, Evalue=3e-35,
Organism=Escherichia coli, GI1786364, Length=252, Percent_Identity=38.4920634920635, Blast_Score=181, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI71996291, Length=250, Percent_Identity=32.8, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323273, Length=250, Percent_Identity=33.2, Blast_Score=146, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24583427, Length=248, Percent_Identity=33.8709677419355, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI21355531, Length=249, Percent_Identity=30.5220883534137, Blast_Score=147, Evalue=9e-36,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27835; Mature: 27704

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGIKSKKDIESLRIPNKIVAQTLELLRLEAKEGISLLELDRKAKDFIISQGGRPSFYQ
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHEEECCCCCCEEE
LYGFPQSICISVNQVIIHGIPTDYILKNGDIVGIDIGVEYNGWYGDAAITIGIGDIQETD
EECCCHHHHEEEEEEEEECCCHHHEEECCCEEEEEEEEEECCEECCEEEEEEECCCCCCC
RILIDCAKDTLYEAISKVKIGMRFKELSLILEQAINGRGFVPLRGFCGHGIGRSPHEEPE
CEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEECCHHHCCCCCCCCCCCCC
IPNYLESPHTNQGPKIKEGMVFCLEPMIAQHNGEPVILNDNWSVIAKDGLNGSHYEHTIA
CCCHHCCCCCCCCCCHHHCHHEEECHHHHCCCCCEEEECCCCEEEEECCCCCCCCEEEEE
IVDGKAEILTEV
EECCCHHHHCCC
>Mature Secondary Structure 
AIGIKSKKDIESLRIPNKIVAQTLELLRLEAKEGISLLELDRKAKDFIISQGGRPSFYQ
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHEEECCCCCCEEE
LYGFPQSICISVNQVIIHGIPTDYILKNGDIVGIDIGVEYNGWYGDAAITIGIGDIQETD
EECCCHHHHEEEEEEEEECCCHHHEEECCCEEEEEEEEEECCEECCEEEEEEECCCCCCC
RILIDCAKDTLYEAISKVKIGMRFKELSLILEQAINGRGFVPLRGFCGHGIGRSPHEEPE
CEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEECCHHHCCCCCCCCCCCCC
IPNYLESPHTNQGPKIKEGMVFCLEPMIAQHNGEPVILNDNWSVIAKDGLNGSHYEHTIA
CCCHHCCCCCCCCCCHHHCHHEEECHHHHCCCCCEEEECCCCEEEEECCCCCCCCEEEEE
IVDGKAEILTEV
EECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]