| Definition | Helicobacter hepaticus ATCC 51449 chromosome, complete genome. |
|---|---|
| Accession | NC_004917 |
| Length | 1,799,146 |
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The map label for this gene is speA
Identifier: 32266732
GI number: 32266732
Start: 1198153
End: 1200006
Strand: Direct
Name: speA
Synonym: HH1233
Alternate gene names: 32266732
Gene position: 1198153-1200006 (Clockwise)
Preceding gene: 32266730
Following gene: 32266733
Centisome position: 66.6
GC content: 36.46
Gene sequence:
>1854_bases ATGGTTGATTATGGGATTAATTTTTGGGCGAATAATGATTTTATCATTAAAGATGGCAAGGTCAAAGTCAATTTTAAACA CAAACCAGCACTTATTGATATTGTCCAAGATGCAAGAGAAAAAGGATACAAAGGACCGCTATTATTGAGATTTCCGCATT TAATTAAAAATCAAGTTGATAAAGTATTCAAAGCCTTTGAAAGTGCAATTAAAGAGTATTCTTATAAGGGAAAGTTTAAG GCAGTTTTTCCTCTAAAAGTAAATCAAATGCCAAATTTTGTGCTTCCTCTAGTGGAACAAAGCCAAGATAAATGCTATGG ATTAGAAGCAGGGAGTAAATCAGAGCTTATTTTAGCTATGGCTTATGTTAATAAAAACGCGCCCATAACCGTCAATGGAT TCAAAGATAAAGAGATGATTTCGCTTGGCTTTAGCGCTGCTAATATGGGACACGATATTACGCTTACAATTGAGGGTTTA AATGAGCTAGAAACAATTATTGAAGTAGCAAAAGAGTTGGGCGAACCTTATCCTAATATCGGACTTAGAATCCGCCTCCA TAGTATAGGCGTAGGCATTTGGGCAAAAAGTGGGGGCATAAATTCAAAATTTGGACTTACAAGTACGGAGCTTTTAGAGG CGATTAATATGCTTGAAAAAGAGCAGCTATTACATAAATTTACAATGATTCATTTTCATATTGGCAGTCAAATGAGCGAT ATTTCACCTCTTAAAAAGGCTATTAGAGAAGCGGGAAATATATATGCAGAATTGCGTAAAAAAGGTGCGAAGAATCTTCA ATGCGTCAATATCGGCGGTGGTTTGGCAGTAGAATACACGCAGCACGAGGGCAAAAATAGTTGCAATTATACATTGAGCG AGTTTAGCGGTGATGTGGTGTTTTCATTGCGAGAAATTGCTAAAAACAAAAAAGAACCCGAACCTGATATTCTTATAGAA TCCGGACGTTTTATTGCTGCAAATCACGCTGTGCTAATCGCACCCGTGCTAGAGCTTTTTTCTCAAGAGTATGATGAAAA AGCTCTTAAGCTTAAAAAACATAATCCGCCGCTTATTGAAGAGCTCTTTGACCTTTATAATAGCGTGGTGGAGAAAAACG CTATTGAATATTTGCACGATAGTCTTGATCATATGGAATCTTTGCTTACACTTTTTGATTTAGGCTATATTGACTTGCAA GATCGCTCTAATACTGAAGTGCTCGTGCATTTGATTATTAAAAAGGTCATTAAGCTTTTAAAGCATAAAAGTCATAATGA GATTCTCCAAATACAAGAGCAAGTGCAAGAGCGGTATTTGCTTAATTGTAGCTTTTTTCAGAGCCTGCCTGATTATTGGG GATTGGGGCAAAACTTTCCGGTAATGCCTCTTGATAGGCTTAATCGCCGCCCGAATAGAAGTGCGAGTTTGTGGGATATT ACTTGTGATTCTGATGGGGAAATTGCTTTTAATCCTATGCAGCCGCTTTTTTTACACGATGTTGATGTAACCAAAGAAGA ATACTTTTTAGGGTTTTTTCTTGTAGGAGCATATCAGGAAGTGCTAAGTATGCGACATAATCTTTTTACTCACCCTACTG AATTTAGTATTGAATTTGATGATGATCTTAATAAGGGCTACGAAATTACGCGTTTGATTGAAGCTCAAACGAGTTTAGAT GTGCTTGATGATTTAGATTATGATACCAAAGAGATTGAGCGCCGCTTAAAACAGCATATTGAAGAAAATCAGAATCTTGA TGAAGAAGGCAAAAAAGAAATGCTTGGACAACTTTATGTAATGCTAAGTGAAAATAGTTATCTACGCACTATTGCTACCA AAGGGAGAGAATAA
Upstream 100 bases:
>100_bases GCTCATTTTTGCTCCATTGAGTATAAAAATATAGTGAAGTATATCCACAAAATGATATAATTCAAACTCATTTTGTAATT TATACTCATAAGGAAATATT
Downstream 100 bases:
>100_bases TGACTTTGTGGGGCATTATCAAAGAAGATTTTAGTATTATTAAACAAAAAGATCCAGCACTTAATAGCAGCGTGGAGTTA TTTTTTAATTATCCGGGTTT
Product: arginine decarboxylase
Products: NA
Alternate protein names: ADC [H]
Number of amino acids: Translated: 617; Mature: 617
Protein sequence:
>617_residues MVDYGINFWANNDFIIKDGKVKVNFKHKPALIDIVQDAREKGYKGPLLLRFPHLIKNQVDKVFKAFESAIKEYSYKGKFK AVFPLKVNQMPNFVLPLVEQSQDKCYGLEAGSKSELILAMAYVNKNAPITVNGFKDKEMISLGFSAANMGHDITLTIEGL NELETIIEVAKELGEPYPNIGLRIRLHSIGVGIWAKSGGINSKFGLTSTELLEAINMLEKEQLLHKFTMIHFHIGSQMSD ISPLKKAIREAGNIYAELRKKGAKNLQCVNIGGGLAVEYTQHEGKNSCNYTLSEFSGDVVFSLREIAKNKKEPEPDILIE SGRFIAANHAVLIAPVLELFSQEYDEKALKLKKHNPPLIEELFDLYNSVVEKNAIEYLHDSLDHMESLLTLFDLGYIDLQ DRSNTEVLVHLIIKKVIKLLKHKSHNEILQIQEQVQERYLLNCSFFQSLPDYWGLGQNFPVMPLDRLNRRPNRSASLWDI TCDSDGEIAFNPMQPLFLHDVDVTKEEYFLGFFLVGAYQEVLSMRHNLFTHPTEFSIEFDDDLNKGYEITRLIEAQTSLD VLDDLDYDTKEIERRLKQHIEENQNLDEEGKKEMLGQLYVMLSENSYLRTIATKGRE
Sequences:
>Translated_617_residues MVDYGINFWANNDFIIKDGKVKVNFKHKPALIDIVQDAREKGYKGPLLLRFPHLIKNQVDKVFKAFESAIKEYSYKGKFK AVFPLKVNQMPNFVLPLVEQSQDKCYGLEAGSKSELILAMAYVNKNAPITVNGFKDKEMISLGFSAANMGHDITLTIEGL NELETIIEVAKELGEPYPNIGLRIRLHSIGVGIWAKSGGINSKFGLTSTELLEAINMLEKEQLLHKFTMIHFHIGSQMSD ISPLKKAIREAGNIYAELRKKGAKNLQCVNIGGGLAVEYTQHEGKNSCNYTLSEFSGDVVFSLREIAKNKKEPEPDILIE SGRFIAANHAVLIAPVLELFSQEYDEKALKLKKHNPPLIEELFDLYNSVVEKNAIEYLHDSLDHMESLLTLFDLGYIDLQ DRSNTEVLVHLIIKKVIKLLKHKSHNEILQIQEQVQERYLLNCSFFQSLPDYWGLGQNFPVMPLDRLNRRPNRSASLWDI TCDSDGEIAFNPMQPLFLHDVDVTKEEYFLGFFLVGAYQEVLSMRHNLFTHPTEFSIEFDDDLNKGYEITRLIEAQTSLD VLDDLDYDTKEIERRLKQHIEENQNLDEEGKKEMLGQLYVMLSENSYLRTIATKGRE >Mature_617_residues MVDYGINFWANNDFIIKDGKVKVNFKHKPALIDIVQDAREKGYKGPLLLRFPHLIKNQVDKVFKAFESAIKEYSYKGKFK AVFPLKVNQMPNFVLPLVEQSQDKCYGLEAGSKSELILAMAYVNKNAPITVNGFKDKEMISLGFSAANMGHDITLTIEGL NELETIIEVAKELGEPYPNIGLRIRLHSIGVGIWAKSGGINSKFGLTSTELLEAINMLEKEQLLHKFTMIHFHIGSQMSD ISPLKKAIREAGNIYAELRKKGAKNLQCVNIGGGLAVEYTQHEGKNSCNYTLSEFSGDVVFSLREIAKNKKEPEPDILIE SGRFIAANHAVLIAPVLELFSQEYDEKALKLKKHNPPLIEELFDLYNSVVEKNAIEYLHDSLDHMESLLTLFDLGYIDLQ DRSNTEVLVHLIIKKVIKLLKHKSHNEILQIQEQVQERYLLNCSFFQSLPDYWGLGQNFPVMPLDRLNRRPNRSASLWDI TCDSDGEIAFNPMQPLFLHDVDVTKEEYFLGFFLVGAYQEVLSMRHNLFTHPTEFSIEFDDDLNKGYEITRLIEAQTSLD VLDDLDYDTKEIERRLKQHIEENQNLDEEGKKEMLGQLYVMLSENSYLRTIATKGRE
Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]
COG id: COG1166
COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]
Homologues:
Organism=Escherichia coli, GI1789307, Length=628, Percent_Identity=32.0063694267516, Blast_Score=325, Evalue=6e-90,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009006 - InterPro: IPR002985 - InterPro: IPR022643 - InterPro: IPR022657 - InterPro: IPR022644 - InterPro: IPR022653 - InterPro: IPR000183 [H]
Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]
EC number: =4.1.1.19 [H]
Molecular weight: Translated: 70502; Mature: 70502
Theoretical pI: Translated: 5.63; Mature: 5.63
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVDYGINFWANNDFIIKDGKVKVNFKHKPALIDIVQDAREKGYKGPLLLRFPHLIKNQVD CCCCCEEEEECCCEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHH KVFKAFESAIKEYSYKGKFKAVFPLKVNQMPNFVLPLVEQSQDKCYGLEAGSKSELILAM HHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCEECCCCCCCCCEEEEE AYVNKNAPITVNGFKDKEMISLGFSAANMGHDITLTIEGLNELETIIEVAKELGEPYPNI EEECCCCCEEEECCCCCHHHEECCHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCC GLRIRLHSIGVGIWAKSGGINSKFGLTSTELLEAINMLEKEQLLHKFTMIHFHIGSQMSD CEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHH ISPLKKAIREAGNIYAELRKKGAKNLQCVNIGGGLAVEYTQHEGKNSCNYTLSEFSGDVV HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCCCEEHHHCCCHHH FSLREIAKNKKEPEPDILIESGRFIAANHAVLIAPVLELFSQEYDEKALKLKKHNPPLIE HHHHHHHHCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH ELFDLYNSVVEKNAIEYLHDSLDHMESLLTLFDLGYIDLQDRSNTEVLVHLIIKKVIKLL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHH KHKSHNEILQIQEQVQERYLLNCSFFQSLPDYWGLGQNFPVMPLDRLNRRPNRSASLWDI HCCCCHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEE TCDSDGEIAFNPMQPLFLHDVDVTKEEYFLGFFLVGAYQEVLSMRHNLFTHPTEFSIEFD EECCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC DDLNKGYEITRLIEAQTSLDVLDDLDYDTKEIERRLKQHIEENQNLDEEGKKEMLGQLYV CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEE MLSENSYLRTIATKGRE EECCCCEEEHHHCCCCC >Mature Secondary Structure MVDYGINFWANNDFIIKDGKVKVNFKHKPALIDIVQDAREKGYKGPLLLRFPHLIKNQVD CCCCCEEEEECCCEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHH KVFKAFESAIKEYSYKGKFKAVFPLKVNQMPNFVLPLVEQSQDKCYGLEAGSKSELILAM HHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCEECCCCCCCCCEEEEE AYVNKNAPITVNGFKDKEMISLGFSAANMGHDITLTIEGLNELETIIEVAKELGEPYPNI EEECCCCCEEEECCCCCHHHEECCHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCC GLRIRLHSIGVGIWAKSGGINSKFGLTSTELLEAINMLEKEQLLHKFTMIHFHIGSQMSD CEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHH ISPLKKAIREAGNIYAELRKKGAKNLQCVNIGGGLAVEYTQHEGKNSCNYTLSEFSGDVV HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCCCEEHHHCCCHHH FSLREIAKNKKEPEPDILIESGRFIAANHAVLIAPVLELFSQEYDEKALKLKKHNPPLIE HHHHHHHHCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH ELFDLYNSVVEKNAIEYLHDSLDHMESLLTLFDLGYIDLQDRSNTEVLVHLIIKKVIKLL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHH KHKSHNEILQIQEQVQERYLLNCSFFQSLPDYWGLGQNFPVMPLDRLNRRPNRSASLWDI HCCCCHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEE TCDSDGEIAFNPMQPLFLHDVDVTKEEYFLGFFLVGAYQEVLSMRHNLFTHPTEFSIEFD EECCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC DDLNKGYEITRLIEAQTSLDVLDDLDYDTKEIERRLKQHIEENQNLDEEGKKEMLGQLYV CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEE MLSENSYLRTIATKGRE EECCCCEEEHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA