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The map label for this gene is ucpA [C]

Identifier: 32266657

GI number: 32266657

Start: 1123611

End: 1124375

Strand: Direct

Name: ucpA [C]

Synonym: HH1158

Alternate gene names: 32266657

Gene position: 1123611-1124375 (Clockwise)

Preceding gene: 32266654

Following gene: 32266663

Centisome position: 62.45

GC content: 36.86

Gene sequence:

>765_bases
ATGAATACTTTTCGTGTGGCAATTACAGGAGCGAGCAGTGGTATAGGTAGAGCATTAGCAATTTGTTTTGCAAATGAGGC
AACTCATTTATATATTGCAGGACGCAATAAGGAGCGATTAGAAGAGAGTAGAGCATATATTTTAGCTGCAAATCCTCAAG
CACAAGTAGAAATTTCTTGTTTTGATGTAAGCGATGAAAAGTCGTGCAAACTTTGGTGTGAAGAAATATTTGTCTCTCGC
CTTGATGTGCTTATTATAAATGCAGGGGTTGCGATGGGAGAAAAAGAGAGTGTAAAAAAACATTTTGAAATTTGTCATAC
AAATGTTATGGGTGTAGCCTATATTGCATTTTACGCACTTGAAGCATTCCGTAAGCAAGAATTAAAAGATAAAAAGAGAG
GACAAATAGTGCTTATGGCATCTATTGCAGCACTTCTTTCATTGCCAAATGCACCAAGTTATAGTGCTTCAAAGAGTTTT
GTTAAAAGTTTGGGAGAAAGTTTGAGCGTGGCGCAAAAAGATGTGCATATTACAACTATTTGTCCGGGGTTTATTAAAAC
GCCACTGACAGATTATATTCACCATTCTATTCCACAAATGAGTGTTGAACAGGCAAGTAAAAAGATGTATTATGCGATTA
AGAAAGGCAAAAGTTTCTACGCATTTCCACACTCTTTAGCGTATGCAGCAAGATTCTATACTATTTTACCATTTTGGCTC
AAACGCGCACTTGTGAATCTTATAGGCTTTATGGGGAGGCTATAA

Upstream 100 bases:

>100_bases
ATCATCTTATCCCTTGAAAATTAAATGCTAAAGTGCAAAAAGCGATTGTAGCATATTTGCTATAATAGTCATATTTTTAT
TGATTTTGAGAGGATAAGAA

Downstream 100 bases:

>100_bases
GTTTAAGTTAATGCTCTTGTGCATTTTCAAGGGCTTTTGTAGCTTCATTGGCGTGTGCTTTGGTATTGTGATAGAGCATA
TATATTGCTGTTTCCCATAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MNTFRVAITGASSGIGRALAICFANEATHLYIAGRNKERLEESRAYILAANPQAQVEISCFDVSDEKSCKLWCEEIFVSR
LDVLIINAGVAMGEKESVKKHFEICHTNVMGVAYIAFYALEAFRKQELKDKKRGQIVLMASIAALLSLPNAPSYSASKSF
VKSLGESLSVAQKDVHITTICPGFIKTPLTDYIHHSIPQMSVEQASKKMYYAIKKGKSFYAFPHSLAYAARFYTILPFWL
KRALVNLIGFMGRL

Sequences:

>Translated_254_residues
MNTFRVAITGASSGIGRALAICFANEATHLYIAGRNKERLEESRAYILAANPQAQVEISCFDVSDEKSCKLWCEEIFVSR
LDVLIINAGVAMGEKESVKKHFEICHTNVMGVAYIAFYALEAFRKQELKDKKRGQIVLMASIAALLSLPNAPSYSASKSF
VKSLGESLSVAQKDVHITTICPGFIKTPLTDYIHHSIPQMSVEQASKKMYYAIKKGKSFYAFPHSLAYAARFYTILPFWL
KRALVNLIGFMGRL
>Mature_254_residues
MNTFRVAITGASSGIGRALAICFANEATHLYIAGRNKERLEESRAYILAANPQAQVEISCFDVSDEKSCKLWCEEIFVSR
LDVLIINAGVAMGEKESVKKHFEICHTNVMGVAYIAFYALEAFRKQELKDKKRGQIVLMASIAALLSLPNAPSYSASKSF
VKSLGESLSVAQKDVHITTICPGFIKTPLTDYIHHSIPQMSVEQASKKMYYAIKKGKSFYAFPHSLAYAARFYTILPFWL
KRALVNLIGFMGRL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI142976729, Length=246, Percent_Identity=28.0487804878049, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=27.979274611399, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=215, Percent_Identity=26.9767441860465, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=219, Percent_Identity=29.6803652968037, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=215, Percent_Identity=29.3023255813954, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=188, Percent_Identity=32.9787234042553, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=219, Percent_Identity=29.2237442922374, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=214, Percent_Identity=32.2429906542056, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=227, Percent_Identity=28.1938325991189, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=193, Percent_Identity=30.0518134715026, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=187, Percent_Identity=28.3422459893048, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=211, Percent_Identity=27.9620853080569, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=234, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=234, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=25.4681647940075, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=209, Percent_Identity=29.6650717703349, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=187, Percent_Identity=27.807486631016, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007236, Length=222, Percent_Identity=28.8288288288288, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=30.3664921465969, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=199, Percent_Identity=30.6532663316583, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=27.2251308900524, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24580925, Length=262, Percent_Identity=28.6259541984733, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=32.9842931937173, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28291; Mature: 28291

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFRVAITGASSGIGRALAICFANEATHLYIAGRNKERLEESRAYILAANPQAQVEISC
CCEEEEEEECCCCCHHHEEEEEEECCCCEEEEECCCHHHHHHCCEEEEEECCCCEEEEEE
FDVSDEKSCKLWCEEIFVSRLDVLIINAGVAMGEKESVKKHFEICHTNVMGVAYIAFYAL
EECCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAFRKQELKDKKRGQIVLMASIAALLSLPNAPSYSASKSFVKSLGESLSVAQKDVHITTI
HHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEE
CPGFIKTPLTDYIHHSIPQMSVEQASKKMYYAIKKGKSFYAFPHSLAYAARFYTILPFWL
CCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHH
KRALVNLIGFMGRL
HHHHHHHHHHHCCC
>Mature Secondary Structure
MNTFRVAITGASSGIGRALAICFANEATHLYIAGRNKERLEESRAYILAANPQAQVEISC
CCEEEEEEECCCCCHHHEEEEEEECCCCEEEEECCCHHHHHHCCEEEEEECCCCEEEEEE
FDVSDEKSCKLWCEEIFVSRLDVLIINAGVAMGEKESVKKHFEICHTNVMGVAYIAFYAL
EECCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAFRKQELKDKKRGQIVLMASIAALLSLPNAPSYSASKSFVKSLGESLSVAQKDVHITTI
HHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEE
CPGFIKTPLTDYIHHSIPQMSVEQASKKMYYAIKKGKSFYAFPHSLAYAARFYTILPFWL
CCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHH
KRALVNLIGFMGRL
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]