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The map label for this gene is 32266407

Identifier: 32266407

GI number: 32266407

Start: 881691

End: 882740

Strand: Direct

Name: 32266407

Synonym: HH0908

Alternate gene names: NA

Gene position: 881691-882740 (Clockwise)

Preceding gene: 32266406

Following gene: 32266408

Centisome position: 49.01

GC content: 39.24

Gene sequence:

>1050_bases
ATGAGCATATCAAAACATATCGCTAAATCCCATACTCCCCTTATTATCGCCGAACTTAGTGCAAATCACAACCAAAGCCT
AGAAATTGCTAAAGATTCTATTCGTGCGATTGCCGCTTGTGGCGCTGATGGCGTGAAACTACAAACTTATACGCCAGAAT
GCCTCACACTTCAATCAAATGAGCCACATTTTTGCATTAGTGGTGGCACACTTTGGGATAAACGCAATCTCTATGAACTT
TATAAAGAAGCCCAAACTCCTTGGGAATGGCATAAAGAACTTTTTTCTCTTGCAAAAGAGTTAGGTTTGCTTATTTTTAG
CTCACCTTTTTCACCTAAAGGTGTTGCATTTTTAGAATCTTTGCAATGCCCGATTTATAAAGTAGCAAGTTTTGAAGTAA
TGCACTATGAGCTTATAGAAGCCATTGCCAAAACAAAAAAGCCAATCATTATTTCCACAGGCGTAGCTACGCACAAAGAA
CTTAAAACTGCACTTGAGATTTGTCATAAATATGGCTGTAAGGATATTACCTTACTTCATTGCATAAGTGAATATCCTGC
CCCATTAGAATCTGCAAATCTCCTTGCTATGCCTCAACTTGCTAAAACCTATAAAAAATACAATATCAAATATGGATTAT
CTGACCATACACTTGGTGCACTTTGTCCAAGTATCGCTACAAGCTTAGGAGCAAGTATGATTGAGAAGCATTTTATTCTT
GACTCCTCACTTGGTGGTGTAGATAGCGCCTTTAGTATGAATAAAGATGAATTTAAAGCTATGGTAGAGCAAGTGCGCGA
TACCGCTTTGGCATTAGGGTGCAAAAAACCTAAAATTTCCGCAGATATACGCAAAAAAAGGCGACAATTTGCACGAAGCA
TTTGGGTAAGTGCAGATATTAAAAAAGGTGAAAAATTCACGCACAAAAATCTCTCTGTCGTGCGTCCTAGCGGCGGAGAA
CACCCACGATATTTGCATAAGATTCTAGGCAAGAGTGCCAAAGTCGCACTCAAAGCTGCACAGCCTCTCCGATTAAGTGA
TGTCAAATAG

Upstream 100 bases:

>100_bases
CAGGTTATATATATGAAGGCGTGTTGCATAATTTTATCGCTCAAAAAGAAAAAGATACAAGACGATATTATGATGTCATA
TTGATGTATAAGGAACATTT

Downstream 100 bases:

>100_bases
TTAAAGTAAAGAGATTTTAAAGTATAATGTGCTTTTATTTCTTTTTATTCATTTAAGGAGTGAGTATGCTACTTTTTACG
CCCGGACCTACACCTGTGCC

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSISKHIAKSHTPLIIAELSANHNQSLEIAKDSIRAIAACGADGVKLQTYTPECLTLQSNEPHFCISGGTLWDKRNLYEL
YKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKVASFEVMHYELIEAIAKTKKPIIISTGVATHKE
LKTALEICHKYGCKDITLLHCISEYPAPLESANLLAMPQLAKTYKKYNIKYGLSDHTLGALCPSIATSLGASMIEKHFIL
DSSLGGVDSAFSMNKDEFKAMVEQVRDTALALGCKKPKISADIRKKRRQFARSIWVSADIKKGEKFTHKNLSVVRPSGGE
HPRYLHKILGKSAKVALKAAQPLRLSDVK

Sequences:

>Translated_349_residues
MSISKHIAKSHTPLIIAELSANHNQSLEIAKDSIRAIAACGADGVKLQTYTPECLTLQSNEPHFCISGGTLWDKRNLYEL
YKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKVASFEVMHYELIEAIAKTKKPIIISTGVATHKE
LKTALEICHKYGCKDITLLHCISEYPAPLESANLLAMPQLAKTYKKYNIKYGLSDHTLGALCPSIATSLGASMIEKHFIL
DSSLGGVDSAFSMNKDEFKAMVEQVRDTALALGCKKPKISADIRKKRRQFARSIWVSADIKKGEKFTHKNLSVVRPSGGE
HPRYLHKILGKSAKVALKAAQPLRLSDVK
>Mature_348_residues
SISKHIAKSHTPLIIAELSANHNQSLEIAKDSIRAIAACGADGVKLQTYTPECLTLQSNEPHFCISGGTLWDKRNLYELY
KEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKVASFEVMHYELIEAIAKTKKPIIISTGVATHKEL
KTALEICHKYGCKDITLLHCISEYPAPLESANLLAMPQLAKTYKKYNIKYGLSDHTLGALCPSIATSLGASMIEKHFILD
SSLGGVDSAFSMNKDEFKAMVEQVRDTALALGCKKPKISADIRKKRRQFARSIWVSADIKKGEKFTHKNLSVVRPSGGEH
PRYLHKILGKSAKVALKAAQPLRLSDVK

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=341, Percent_Identity=26.9794721407625, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357081, Length=358, Percent_Identity=24.8603351955307, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38691; Mature: 38560

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISKHIAKSHTPLIIAELSANHNQSLEIAKDSIRAIAACGADGVKLQTYTPECLTLQSN
CCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECC
EPHFCISGGTLWDKRNLYELYKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLES
CCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHH
LQCPIYKVASFEVMHYELIEAIAKTKKPIIISTGVATHKELKTALEICHKYGCKDITLLH
CCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHH
CISEYPAPLESANLLAMPQLAKTYKKYNIKYGLSDHTLGALCPSIATSLGASMIEKHFIL
HHHHCCCCCCCCCEEECHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DSSLGGVDSAFSMNKDEFKAMVEQVRDTALALGCKKPKISADIRKKRRQFARSIWVSADI
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
KKGEKFTHKNLSVVRPSGGEHPRYLHKILGKSAKVALKAAQPLRLSDVK
CCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SISKHIAKSHTPLIIAELSANHNQSLEIAKDSIRAIAACGADGVKLQTYTPECLTLQSN
CCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECC
EPHFCISGGTLWDKRNLYELYKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLES
CCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHH
LQCPIYKVASFEVMHYELIEAIAKTKKPIIISTGVATHKELKTALEICHKYGCKDITLLH
CCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHH
CISEYPAPLESANLLAMPQLAKTYKKYNIKYGLSDHTLGALCPSIATSLGASMIEKHFIL
HHHHCCCCCCCCCEEECHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DSSLGGVDSAFSMNKDEFKAMVEQVRDTALALGCKKPKISADIRKKRRQFARSIWVSADI
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
KKGEKFTHKNLSVVRPSGGEHPRYLHKILGKSAKVALKAAQPLRLSDVK
CCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]