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The map label for this gene is alr

Identifier: 32265965

GI number: 32265965

Start: 449135

End: 450376

Strand: Direct

Name: alr

Synonym: HH0466

Alternate gene names: 32265965

Gene position: 449135-450376 (Clockwise)

Preceding gene: 32265955

Following gene: 32265966

Centisome position: 24.96

GC content: 34.7

Gene sequence:

>1242_bases
ATGAATATATTTAAAACTGGATTTACTACCCTATTACTTATGGGAATACTTGCTAGTGCAAATTTTGCCTCGCCTATACT
TGTTGAGAGCACAAATGTGAACAAAAACAATACAAACTCTTTTATGGAAGTTGATATAAAAGCCTTTAAAAATAATATCA
AAGTTGCCAAAAAAATAGCAGGAAATGCTAAAGTTTGTGCAGTTTTAAAAGCCAATGCTTATGGGGCTGGAATAAGCAAA
GTGTTGCCCACTATCATAGAAGAAAAAATCCCTTGTGTGGCTATTACAAGCAATGAAGAAGCAAGAGTTATCCGCAAAAT
GAAATATACAGGCGAGATTCTACGAATACGAACAGCCACAATGGGAGAAATAAAAGATGGTTTAAAATATAACATCACAG
AAGTTTTGGGAAATTTAGATCAAGCAAAAAAAGTAGATTCTCTAGCAAAGACGATAGGCAAAAAACTTCCCATTCATATC
AAACTCAATTCAGGTGGAATGGATAGAAATGGTATTGATTTAAGCACTGATAAAGGCAAAGAATCTGCAGTTAAGTTAGC
TACTTTGCCACATCTTAAAATAAAAGGGCTAATGACACATTTTCCTTATGATGATACCTCAAAAGTAAAGGAAAATTTAA
AACATTTTGAAGAAGATACGGATTTTCTAATAAGTAAAGCAAAACTTGATAGAAATAAACTTGTGCTGCACGCTGCTGCC
TCATATGCAGCAGTGCAAGTGCCTCAATCAAGGTTAGATATGATACGACCCGGAAAGCTTATTTATGGCTATGGTGGAGG
AGATGAAAATCTACCCATACAACAAATTATGAGTTTAAAATCTCAAGTAGCAGTTATAAATGAATATCCAAAAGGGAGCA
AAGTAAGCTATGATGGCACTCACACACTTACAAGAGATTCTAAACTCGCCAATATTCCTGTGGGTTATTATGATGGCTAT
GCAAAATCTTTAAGCAATCAAGGAAAAGTGCTTATTAGAGGGCATAAAGTGCCAGTCGTTGGGAGAGTTACAAAAAATAC
TTTTATGGTAGATGTAACCGATTATCCAGATATTAAAGCAGGCGATGAAGTCGTGCTCTTTGGAAAACAATGCGGCAATG
AAATCACTCAAGCCGAATTTGAAAAAGGAACGGGCACGATTCTCTCTGAAACATTAGGATATTGGGGAAGTGCAAATCCT
ATTTTTATTAAAAATTATAAAATGAAAGAAGTATGCAAATAA

Upstream 100 bases:

>100_bases
TAATAAAGTTTCAACATTCAATGTTACAAAATTTAATGTTTTTTCTCCTACTTGGTGTAGAAATATTTTATAAACAAATA
TATATTTTAAGGAGCAAAAG

Downstream 100 bases:

>100_bases
CTTTACAATAATGCAAACATATTCAAAAGTGGCAAAGCATTAAATTTAAAAATTCTTGCTACAATGCCACACTTTATTTT
TTATAATTCAGATGAGTATA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MNIFKTGFTTLLLMGILASANFASPILVESTNVNKNNTNSFMEVDIKAFKNNIKVAKKIAGNAKVCAVLKANAYGAGISK
VLPTIIEEKIPCVAITSNEEARVIRKMKYTGEILRIRTATMGEIKDGLKYNITEVLGNLDQAKKVDSLAKTIGKKLPIHI
KLNSGGMDRNGIDLSTDKGKESAVKLATLPHLKIKGLMTHFPYDDTSKVKENLKHFEEDTDFLISKAKLDRNKLVLHAAA
SYAAVQVPQSRLDMIRPGKLIYGYGGGDENLPIQQIMSLKSQVAVINEYPKGSKVSYDGTHTLTRDSKLANIPVGYYDGY
AKSLSNQGKVLIRGHKVPVVGRVTKNTFMVDVTDYPDIKAGDEVVLFGKQCGNEITQAEFEKGTGTILSETLGYWGSANP
IFIKNYKMKEVCK

Sequences:

>Translated_413_residues
MNIFKTGFTTLLLMGILASANFASPILVESTNVNKNNTNSFMEVDIKAFKNNIKVAKKIAGNAKVCAVLKANAYGAGISK
VLPTIIEEKIPCVAITSNEEARVIRKMKYTGEILRIRTATMGEIKDGLKYNITEVLGNLDQAKKVDSLAKTIGKKLPIHI
KLNSGGMDRNGIDLSTDKGKESAVKLATLPHLKIKGLMTHFPYDDTSKVKENLKHFEEDTDFLISKAKLDRNKLVLHAAA
SYAAVQVPQSRLDMIRPGKLIYGYGGGDENLPIQQIMSLKSQVAVINEYPKGSKVSYDGTHTLTRDSKLANIPVGYYDGY
AKSLSNQGKVLIRGHKVPVVGRVTKNTFMVDVTDYPDIKAGDEVVLFGKQCGNEITQAEFEKGTGTILSETLGYWGSANP
IFIKNYKMKEVCK
>Mature_413_residues
MNIFKTGFTTLLLMGILASANFASPILVESTNVNKNNTNSFMEVDIKAFKNNIKVAKKIAGNAKVCAVLKANAYGAGISK
VLPTIIEEKIPCVAITSNEEARVIRKMKYTGEILRIRTATMGEIKDGLKYNITEVLGNLDQAKKVDSLAKTIGKKLPIHI
KLNSGGMDRNGIDLSTDKGKESAVKLATLPHLKIKGLMTHFPYDDTSKVKENLKHFEEDTDFLISKAKLDRNKLVLHAAA
SYAAVQVPQSRLDMIRPGKLIYGYGGGDENLPIQQIMSLKSQVAVINEYPKGSKVSYDGTHTLTRDSKLANIPVGYYDGY
AKSLSNQGKVLIRGHKVPVVGRVTKNTFMVDVTDYPDIKAGDEVVLFGKQCGNEITQAEFEKGTGTILSETLGYWGSANP
IFIKNYKMKEVCK

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=336, Percent_Identity=26.1904761904762, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790487, Length=333, Percent_Identity=25.5255255255255, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 45299; Mature: 45299

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFKTGFTTLLLMGILASANFASPILVESTNVNKNNTNSFMEVDIKAFKNNIKVAKKIA
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHC
GNAKVCAVLKANAYGAGISKVLPTIIEEKIPCVAITSNEEARVIRKMKYTGEILRIRTAT
CCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECH
MGEIKDGLKYNITEVLGNLDQAKKVDSLAKTIGKKLPIHIKLNSGGMDRNGIDLSTDKGK
HHHHHCCCEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
ESAVKLATLPHLKIKGLMTHFPYDDTSKVKENLKHFEEDTDFLISKAKLDRNKLVLHAAA
CCEEEEEECCCEEEEHHHEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECC
SYAAVQVPQSRLDMIRPGKLIYGYGGGDENLPIQQIMSLKSQVAVINEYPKGSKVSYDGT
CHHEEECCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEECCCCCCEEECCCC
HTLTRDSKLANIPVGYYDGYAKSLSNQGKVLIRGHKVPVVGRVTKNTFMVDVTDYPDIKA
EEEECCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCEEEEEECCEEEEEECCCCCCCC
GDEVVLFGKQCGNEITQAEFEKGTGTILSETLGYWGSANPIFIKNYKMKEVCK
CCEEEEECHHCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEECCCHHHHCC
>Mature Secondary Structure
MNIFKTGFTTLLLMGILASANFASPILVESTNVNKNNTNSFMEVDIKAFKNNIKVAKKIA
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHC
GNAKVCAVLKANAYGAGISKVLPTIIEEKIPCVAITSNEEARVIRKMKYTGEILRIRTAT
CCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECH
MGEIKDGLKYNITEVLGNLDQAKKVDSLAKTIGKKLPIHIKLNSGGMDRNGIDLSTDKGK
HHHHHCCCEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
ESAVKLATLPHLKIKGLMTHFPYDDTSKVKENLKHFEEDTDFLISKAKLDRNKLVLHAAA
CCEEEEEECCCEEEEHHHEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECC
SYAAVQVPQSRLDMIRPGKLIYGYGGGDENLPIQQIMSLKSQVAVINEYPKGSKVSYDGT
CHHEEECCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEECCCCCCEEECCCC
HTLTRDSKLANIPVGYYDGYAKSLSNQGKVLIRGHKVPVVGRVTKNTFMVDVTDYPDIKA
EEEECCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCEEEEEECCEEEEEECCCCCCCC
GDEVVLFGKQCGNEITQAEFEKGTGTILSETLGYWGSANPIFIKNYKMKEVCK
CCEEEEECHHCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]