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The map label for this gene is galE

Identifier: 32265879

GI number: 32265879

Start: 371691

End: 372728

Strand: Direct

Name: galE

Synonym: HH0380

Alternate gene names: 32265879

Gene position: 371691-372728 (Clockwise)

Preceding gene: 32265878

Following gene: 32265880

Centisome position: 20.66

GC content: 37.09

Gene sequence:

>1038_bases
ATGCCTTATCTTTTGCTTACAGGTGCAAGTGGCTACATCGGTTCTCATACTGCTTATTGTCTTTTGAAAAATACAAATTA
TCATATTCTTATCGTTGATGATTTAAGCACAGGCTTTAAAGAAAACATTGCTTATCTCCAAGAATGCTTTGAGGAGCGAG
TGAGTTTTGTGCAAAGCAATATCAACGATATATCCAAAATGCGCACTTTGCTCTTGCACTATAAATTTGAGGCAGTGATT
CACTTTGCGGCTTCGCTTATTGTTGGAGAATCTGTGCTCAAACCCCTTGAATACTATACAAACAACACCCTTAATACTAC
AAATCTTATTGCCTTGTGCATAGAATGCGGCATAACAAAATTTATCTTTAGCTCTACAGCAGCAGTATATGGAGAGCCAC
ATACTTCACTTATCCCTATTGATGAGAATGCCCCACTTTTACCTATTAATCCTTATGGAAGCTCAAAAATGATGAGCGAG
CGAATCTTATACGATACTTCACTTGCATTCAAAAACTTTAATTATGTAGCATTGCGATATTTTAATGTCGCAGGAGCGAG
TATGGATAACACGCCACAGATTCTCTCAAACCATAAAGGCTTGGGGCAAAGGAGCAAAAATGCTACTCATCTTATCAAAG
TCGCTTGTGAGTGTGCTTGTGGCAAAAGAGAATCTATGAGTATCTTTGGCACAGATTATCCCACAAAGGACGGCACTTGT
ATCCGCGATTATATTCATATTGATGATTTAGCAAGTGCGCATCTTGAAGCTCTTACATTTTTACAGCATACACAAACTTC
CAATATTTTTAATGTAGGCTATTGCAAAGGATATAGTGTAAAAGAAGTAATTGATGTTGTCAAAGAAATCAGCGGAATGG
ATTTTAAAGTTATAGAATCTGCTCGTAGAGAGGGCGACCCTATTGAGCTAAGTGCCAAAAATGAAAAGATTCTCTCCCTT
ACGCAATGGAAACCAAAATATAATGATTTAAGAGTGATTGTCAAAAGTGCTTATGAATGGGAGTGTTCATTGAAATAA

Upstream 100 bases:

>100_bases
CTCTTGTGTAGCAGGATATTTGCTTGCAAAGGTTGCAGGATATATTTAGCTTAACTTGATAGAATCTAAATGCGGATTCT
ATCAAGTTTAAGGAGCATAT

Downstream 100 bases:

>100_bases
AGGAGGGAAGCAATGAATGAAATATAATGTCTTAGCAATCATTGGAATCTTAATAGTATTTTTTATGATAAAAGGTTGTT
CTTATCCTACAAGTTATCGT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPYLLLTGASGYIGSHTAYCLLKNTNYHILIVDDLSTGFKENIAYLQECFEERVSFVQSNINDISKMRTLLLHYKFEAVI
HFAASLIVGESVLKPLEYYTNNTLNTTNLIALCIECGITKFIFSSTAAVYGEPHTSLIPIDENAPLLPINPYGSSKMMSE
RILYDTSLAFKNFNYVALRYFNVAGASMDNTPQILSNHKGLGQRSKNATHLIKVACECACGKRESMSIFGTDYPTKDGTC
IRDYIHIDDLASAHLEALTFLQHTQTSNIFNVGYCKGYSVKEVIDVVKEISGMDFKVIESARREGDPIELSAKNEKILSL
TQWKPKYNDLRVIVKSAYEWECSLK

Sequences:

>Translated_345_residues
MPYLLLTGASGYIGSHTAYCLLKNTNYHILIVDDLSTGFKENIAYLQECFEERVSFVQSNINDISKMRTLLLHYKFEAVI
HFAASLIVGESVLKPLEYYTNNTLNTTNLIALCIECGITKFIFSSTAAVYGEPHTSLIPIDENAPLLPINPYGSSKMMSE
RILYDTSLAFKNFNYVALRYFNVAGASMDNTPQILSNHKGLGQRSKNATHLIKVACECACGKRESMSIFGTDYPTKDGTC
IRDYIHIDDLASAHLEALTFLQHTQTSNIFNVGYCKGYSVKEVIDVVKEISGMDFKVIESARREGDPIELSAKNEKILSL
TQWKPKYNDLRVIVKSAYEWECSLK
>Mature_344_residues
PYLLLTGASGYIGSHTAYCLLKNTNYHILIVDDLSTGFKENIAYLQECFEERVSFVQSNINDISKMRTLLLHYKFEAVIH
FAASLIVGESVLKPLEYYTNNTLNTTNLIALCIECGITKFIFSSTAAVYGEPHTSLIPIDENAPLLPINPYGSSKMMSER
ILYDTSLAFKNFNYVALRYFNVAGASMDNTPQILSNHKGLGQRSKNATHLIKVACECACGKRESMSIFGTDYPTKDGTCI
RDYIHIDDLASAHLEALTFLQHTQTSNIFNVGYCKGYSVKEVIDVVKEISGMDFKVIESARREGDPIELSAKNEKILSLT
QWKPKYNDLRVIVKSAYEWECSLK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=316, Percent_Identity=38.2911392405063, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI56118217, Length=316, Percent_Identity=38.2911392405063, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI189083684, Length=316, Percent_Identity=38.2911392405063, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI7657641, Length=346, Percent_Identity=27.1676300578035, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI42516563, Length=328, Percent_Identity=21.3414634146341, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786974, Length=344, Percent_Identity=35.7558139534884, Blast_Score=202, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71982035, Length=314, Percent_Identity=35.9872611464968, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71982038, Length=316, Percent_Identity=36.0759493670886, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17568069, Length=279, Percent_Identity=26.1648745519713, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=328, Percent_Identity=37.1951219512195, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI19923002, Length=314, Percent_Identity=37.2611464968153, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21356223, Length=329, Percent_Identity=24.0121580547112, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38749; Mature: 38618

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYLLLTGASGYIGSHTAYCLLKNTNYHILIVDDLSTGFKENIAYLQECFEERVSFVQSN
CCEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
INDISKMRTLLLHYKFEAVIHFAASLIVGESVLKPLEYYTNNTLNTTNLIALCIECGITK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHH
FIFSSTAAVYGEPHTSLIPIDENAPLLPINPYGSSKMMSERILYDTSLAFKNFNYVALRY
HHHHCCHHEECCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
FNVAGASMDNTPQILSNHKGLGQRSKNATHLIKVACECACGKRESMSIFGTDYPTKDGTC
EEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCE
IRDYIHIDDLASAHLEALTFLQHTQTSNIFNVGYCKGYSVKEVIDVVKEISGMDFKVIES
EEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
ARREGDPIELSAKNEKILSLTQWKPKYNDLRVIVKSAYEWECSLK
HHHCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
PYLLLTGASGYIGSHTAYCLLKNTNYHILIVDDLSTGFKENIAYLQECFEERVSFVQSN
CEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
INDISKMRTLLLHYKFEAVIHFAASLIVGESVLKPLEYYTNNTLNTTNLIALCIECGITK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHH
FIFSSTAAVYGEPHTSLIPIDENAPLLPINPYGSSKMMSERILYDTSLAFKNFNYVALRY
HHHHCCHHEECCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
FNVAGASMDNTPQILSNHKGLGQRSKNATHLIKVACECACGKRESMSIFGTDYPTKDGTC
EEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCE
IRDYIHIDDLASAHLEALTFLQHTQTSNIFNVGYCKGYSVKEVIDVVKEISGMDFKVIES
EEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
ARREGDPIELSAKNEKILSLTQWKPKYNDLRVIVKSAYEWECSLK
HHHCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]