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The map label for this gene is efp

Identifier: 32265607

GI number: 32265607

Start: 106199

End: 106762

Strand: Direct

Name: efp

Synonym: HH0108

Alternate gene names: 32265607

Gene position: 106199-106762 (Clockwise)

Preceding gene: 32265606

Following gene: 32265613

Centisome position: 5.9

GC content: 39.18

Gene sequence:

>564_bases
ATGGCAATTGGAATGAGTGAACTCAAAAAAGGATTAAAAATTGAAATTGATGGGATTCCATATAGAATTACCGAATATCA
ACACGTCAAACCCGGTAAAGGCGCAGCATTTGTGCGAGCAAAAATCAAATCATTCCTTGATGGTAAAGTCATTGAAAAAA
CTTTTCACGCAGGCGATAAATGTGAAGAGCCAAATCTTCAAGAAAAAACAATGCAATTCCTCTATCACGATGGTGGTGCG
TTCCAATTTATGGATACGACCACTTATGAACAAATCGCATTGAGTGATGACCAAGTAGGCGATGTAGCAAAATGGATTAT
TGATGGACTAAACGTGCAGATTCTATTTCATAATGAAAAAGCTATTTCTGTTGATGTGCCCCTTGTCGTAGAACTCACCA
TTACAGAGACTGCGCCAAATTTCAAAGGAGATACAAGTAGTGGCGGCAAAAAGCCTGCTACGCTTGAAACAGGTGCCGTC
GTGCAAGTGCCTTTCCACGTACTTGAAGGAGAAAAGATTAAAGTCAATACAGAAACAGGCGAATATCTTGAAAAAGTCAA
ATAG

Upstream 100 bases:

>100_bases
TGAAAAAATTTAAATATTTACGCCATAAGGTAGTGCTTTAATCTAGGAGTTTATGATATAATAAAGCCTTGAAATTCCCT
ATATTATTTAAGGAGCGTAT

Downstream 100 bases:

>100_bases
CTTAAAATCTACACGCATATAAGAGTGAAACATTTTCTCACTCTTTGGTGTAAATTTTCTATTCTTTTTCTATATGTGTG
CAAATTTCGCCATTTTTAAG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MAIGMSELKKGLKIEIDGIPYRITEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLQEKTMQFLYHDGGA
FQFMDTTTYEQIALSDDQVGDVAKWIIDGLNVQILFHNEKAISVDVPLVVELTITETAPNFKGDTSSGGKKPATLETGAV
VQVPFHVLEGEKIKVNTETGEYLEKVK

Sequences:

>Translated_187_residues
MAIGMSELKKGLKIEIDGIPYRITEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLQEKTMQFLYHDGGA
FQFMDTTTYEQIALSDDQVGDVAKWIIDGLNVQILFHNEKAISVDVPLVVELTITETAPNFKGDTSSGGKKPATLETGAV
VQVPFHVLEGEKIKVNTETGEYLEKVK
>Mature_186_residues
AIGMSELKKGLKIEIDGIPYRITEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLQEKTMQFLYHDGGAF
QFMDTTTYEQIALSDDQVGDVAKWIIDGLNVQILFHNEKAISVDVPLVVELTITETAPNFKGDTSSGGKKPATLETGAVV
QVPFHVLEGEKIKVNTETGEYLEKVK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=44.5054945054945, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI87082061, Length=182, Percent_Identity=30.2197802197802, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_HELHP (Q7VJY4)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859639.1
- ProteinModelPortal:   Q7VJY4
- SMR:   Q7VJY4
- GeneID:   1493864
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0108
- NMPDR:   fig|235279.1.peg.108
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   HHEP235279:HH_0108-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20673; Mature: 20542

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGMSELKKGLKIEIDGIPYRITEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDK
CCCCHHHHCCCCEEEECCCCEEECCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCC
CEEPNLQEKTMQFLYHDGGAFQFMDTTTYEQIALSDDQVGDVAKWIIDGLNVQILFHNEK
CCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCC
AISVDVPLVVELTITETAPNFKGDTSSGGKKPATLETGAVVQVPFHVLEGEKIKVNTETG
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCH
EYLEKVK
HHHHHCC
>Mature Secondary Structure 
AIGMSELKKGLKIEIDGIPYRITEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDK
CCCHHHHCCCCEEEECCCCEEECCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCC
CEEPNLQEKTMQFLYHDGGAFQFMDTTTYEQIALSDDQVGDVAKWIIDGLNVQILFHNEK
CCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCC
AISVDVPLVVELTITETAPNFKGDTSSGGKKPATLETGAVVQVPFHVLEGEKIKVNTETG
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCH
EYLEKVK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954