| Definition | Shigella flexneri 2a str. 2457T, complete genome. |
|---|---|
| Accession | NC_004741 |
| Length | 4,599,354 |
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The map label for this gene is hpaE
Identifier: 30065594
GI number: 30065594
Start: 4546509
End: 4547975
Strand: Reverse
Name: hpaE
Synonym: S4653
Alternate gene names: 30065594
Gene position: 4547975-4546509 (Counterclockwise)
Preceding gene: 30065595
Following gene: 30065593
Centisome position: 98.88
GC content: 58.55
Gene sequence:
>1467_bases ATGAAAAAAGTAAATCATTGGATCAACGGCAAAAATGTTGCAGGTAACGACTACTTCCAGACTACCAATCCGGCAACGGG TGAAGTGCTGGCGGATGTGGCCTCTGGCGGTGAAGCGGAGATCAATCAGGCGGTAGCGGCAGCGAAAGAGGCGTTCCCGA AATGGGCTGATCTGCCGATGAAAGAGCGTGCGCGCCTGATGCGCCGTCTGGGCGATCTGATCGACCAGAACGTGCCTGAG ATCGCCGCGATGGAAACCGCGGACACGGGCCTGCCGATCCATCAGACCAAAAATGTGTTGATCCCACGCGCTTCTCACAA CTTTGAATTTTTCGCGGAAGTCTGCCAGCAGATGAACGGCAAGACCTATCCGGTTGACGACAAGATGCTCAACTACACGC TGGTGCAACCGGTAGGCGTTTGTGCGCTGGCGTCGCCGTGGAACGTGCCGTTTATGACCGCCACCTGGAAGGTCGCGCCG TGTCTGGCGCTGGGCAATACCGCGGTGCTGAAGATGTCGGAACTCTCCCCGCTGACCGCCGACCGCCTGGGTGAGCTGGC GCTGGAAGCTGGTATTCCGGCGGGCGTGCTAAACGTGGTACAGGGCTACGGCGCAACCGCAGGCGATGCGCTGGTCCGTC ATCATGACGTGCGTGCCGTGTCGTTCACCGGCGGTACCGCCACCGGGCGCAACATCATGAAAAACGCCGGGCTGAAAAAA TACTCCATGGAGCTGGGCGGTAAATCACCGGTGCTGATTTTTGAAGATGCCGATATTGAGCGTGCGCTGGACGCCGCCCT GTTCACCATCTTCTCAATCAACGGCGAACGCTGCACCGCCGGTTCGCGCATCTTTATTCAGCAGAGCATCTATCCAGAAT TCGTTAAACGCTTTGCCGAACGCGCCAACCGTCTGCGCGTGGGCGATCCGAACGATCCGAATACCCAGGTTAGGGCGCTT ATCAGTCAGCAACACTGGGAAAAAGTCTCCGGCTATATCCGTCTCGGCATTGAAGAAGGCGCAACCCTGTTGGCGGGCGG CCCGGATAAACCGTCCGACCTGCCTGCGCACCTGAAAGGCGGCAACTTCCTGCGCCCAACGGTGCTGGCGGACGTAGATA ACCGTATGCGCGTTGCCCAGGAAGAGATTTTCGGGCCGGTCGCCTGCCTGCTGCCGTTTAAAGACGAAGCCGAAGGCTTA CGCCTGGCAAACGACGTGGAGTACGGCCTCGCGTCGTACATCTGGACACAGGATGTCAGCAAAGTGTTACGCCTGGCGCG TGGCATTGAAGCAGGCATGGTGTTCGTCAACACCCAGAACGTGCGCGACCTGCGCCAGCCATTTGGCGGCGTAAAAGCCT CCGGCACCGGGCGTGAAGGCGGTGAGTACAGCTTCGAAGTGTTCGCGGAAATGAAGAACGTCTGCATTTCCATGGGCGAC CATCCAATTCCGAAATGGGGAGTCTGA
Upstream 100 bases:
>100_bases CAAAAGGCTTATCTGACGTGGTGCCTGGCGATGAAGTAGTGGTGGAAGTAGAAGGCGTGGGGCGCCTGGTGAACCGAATT GTGAGTGAGGAAACAGCGAA
Downstream 100 bases:
>100_bases TATGGGTAAGTTAGCGTTAGCCGCCAAGATCACGCACGTACCGTCGATGTATCTCTCTGAACTACCAGGAAAAAACCACG GTTGTCGCCAGGGTGCGATC
Product: 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase
Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+
Alternate protein names: CHMS dehydrogenase [H]
Number of amino acids: Translated: 488; Mature: 488
Protein sequence:
>488_residues MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQAVAAAKEAFPKWADLPMKERARLMRRLGDLIDQNVPE IAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALASPWNVPFMTATWKVAP CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPNDPNTQVRAL ISQQHWEKVSGYIRLGIEEGATLLAGGPDKPSDLPAHLKGGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGL RLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD HPIPKWGV
Sequences:
>Translated_488_residues MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQAVAAAKEAFPKWADLPMKERARLMRRLGDLIDQNVPE IAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALASPWNVPFMTATWKVAP CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPNDPNTQVRAL ISQQHWEKVSGYIRLGIEEGATLLAGGPDKPSDLPAHLKGGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGL RLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD HPIPKWGV >Mature_488_residues MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQAVAAAKEAFPKWADLPMKERARLMRRLGDLIDQNVPE IAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALASPWNVPFMTATWKVAP CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPNDPNTQVRAL ISQQHWEKVSGYIRLGIEEGATLLAGGPDKPSDLPAHLKGGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGL RLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD HPIPKWGV
Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) [H]
COG id: COG1012
COG function: function code C; NAD-dependent aldehyde dehydrogenases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldehyde dehydrogenase family [H]
Homologues:
Organism=Homo sapiens, GI12007648, Length=477, Percent_Identity=41.9287211740042, Blast_Score=399, Evalue=1e-111, Organism=Homo sapiens, GI25777730, Length=480, Percent_Identity=41.25, Blast_Score=377, Evalue=1e-104, Organism=Homo sapiens, GI25777732, Length=480, Percent_Identity=41.0416666666667, Blast_Score=364, Evalue=1e-100, Organism=Homo sapiens, GI153266822, Length=482, Percent_Identity=39.2116182572614, Blast_Score=361, Evalue=1e-100, Organism=Homo sapiens, GI25777724, Length=480, Percent_Identity=39.5833333333333, Blast_Score=359, Evalue=4e-99, Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=39.524838012959, Blast_Score=345, Evalue=5e-95, Organism=Homo sapiens, GI238814322, Length=483, Percent_Identity=39.5445134575569, Blast_Score=344, Evalue=9e-95, Organism=Homo sapiens, GI21361176, Length=480, Percent_Identity=38.3333333333333, Blast_Score=338, Evalue=7e-93, Organism=Homo sapiens, GI21614513, Length=466, Percent_Identity=39.9141630901288, Blast_Score=335, Evalue=5e-92, Organism=Homo sapiens, GI25777728, Length=420, Percent_Identity=40.4761904761905, Blast_Score=332, Evalue=4e-91, Organism=Homo sapiens, GI25952152, Length=477, Percent_Identity=36.2683438155136, Blast_Score=315, Evalue=5e-86, Organism=Homo sapiens, GI25777726, Length=477, Percent_Identity=36.2683438155136, Blast_Score=305, Evalue=7e-83, Organism=Homo sapiens, GI301500698, Length=482, Percent_Identity=35.8921161825726, Blast_Score=290, Evalue=2e-78, Organism=Homo sapiens, GI4507229, Length=483, Percent_Identity=35.6107660455487, Blast_Score=270, Evalue=2e-72, Organism=Homo sapiens, GI25777721, Length=496, Percent_Identity=34.4758064516129, Blast_Score=259, Evalue=5e-69, Organism=Homo sapiens, GI11095441, Length=485, Percent_Identity=29.8969072164948, Blast_Score=194, Evalue=1e-49, Organism=Homo sapiens, GI310128093, Length=477, Percent_Identity=27.6729559748428, Blast_Score=194, Evalue=2e-49, Organism=Homo sapiens, GI188035924, Length=495, Percent_Identity=27.0707070707071, Blast_Score=194, Evalue=2e-49, Organism=Homo sapiens, GI310128103, Length=477, Percent_Identity=27.4633123689727, Blast_Score=192, Evalue=5e-49, Organism=Homo sapiens, GI310128091, Length=470, Percent_Identity=27.4468085106383, Blast_Score=173, Evalue=3e-43, Organism=Homo sapiens, GI310128089, Length=339, Percent_Identity=30.6784660766962, Blast_Score=156, Evalue=4e-38, Organism=Homo sapiens, GI223972651, Length=464, Percent_Identity=27.801724137931, Blast_Score=155, Evalue=8e-38, Organism=Homo sapiens, GI238859541, Length=466, Percent_Identity=25.9656652360515, Blast_Score=148, Evalue=9e-36, Organism=Homo sapiens, GI25777736, Length=466, Percent_Identity=25.9656652360515, Blast_Score=148, Evalue=9e-36, Organism=Homo sapiens, GI25777734, Length=466, Percent_Identity=25.9656652360515, Blast_Score=148, Evalue=9e-36, Organism=Homo sapiens, GI310128097, Length=263, Percent_Identity=32.319391634981, Blast_Score=142, Evalue=1e-33, Organism=Homo sapiens, GI310128095, Length=318, Percent_Identity=29.559748427673, Blast_Score=135, Evalue=1e-31, Organism=Homo sapiens, GI4557303, Length=345, Percent_Identity=28.4057971014493, Blast_Score=134, Evalue=2e-31, Organism=Homo sapiens, GI73466520, Length=345, Percent_Identity=28.4057971014493, Blast_Score=134, Evalue=3e-31, Organism=Homo sapiens, GI206597441, Length=450, Percent_Identity=26.2222222222222, Blast_Score=131, Evalue=1e-30, Organism=Homo sapiens, GI206597439, Length=450, Percent_Identity=26.2222222222222, Blast_Score=131, Evalue=1e-30, Organism=Homo sapiens, GI22907049, Length=450, Percent_Identity=26.2222222222222, Blast_Score=131, Evalue=1e-30, Organism=Homo sapiens, GI223972653, Length=462, Percent_Identity=24.8917748917749, Blast_Score=119, Evalue=6e-27, Organism=Homo sapiens, GI73695881, Length=347, Percent_Identity=25.9365994236311, Blast_Score=111, Evalue=2e-24, Organism=Homo sapiens, GI73695879, Length=347, Percent_Identity=25.9365994236311, Blast_Score=111, Evalue=2e-24, Organism=Homo sapiens, GI71773324, Length=342, Percent_Identity=26.9005847953216, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI4502043, Length=342, Percent_Identity=26.9005847953216, Blast_Score=110, Evalue=3e-24, Organism=Homo sapiens, GI238814371, Length=342, Percent_Identity=26.9005847953216, Blast_Score=110, Evalue=3e-24, Organism=Homo sapiens, GI310128087, Length=294, Percent_Identity=24.1496598639456, Blast_Score=101, Evalue=2e-21, Organism=Homo sapiens, GI310128099, Length=236, Percent_Identity=22.4576271186441, Blast_Score=70, Evalue=6e-12, Organism=Homo sapiens, GI310128101, Length=236, Percent_Identity=22.4576271186441, Blast_Score=70, Evalue=6e-12, Organism=Escherichia coli, GI1787558, Length=480, Percent_Identity=39.1666666666667, Blast_Score=341, Evalue=5e-95, Organism=Escherichia coli, GI1789015, Length=478, Percent_Identity=37.8661087866109, Blast_Score=335, Evalue=5e-93, Organism=Escherichia coli, GI87082295, Length=492, Percent_Identity=38.2113821138211, Blast_Score=327, Evalue=1e-90, Organism=Escherichia coli, GI1786504, Length=463, Percent_Identity=38.8768898488121, Blast_Score=325, Evalue=3e-90, Organism=Escherichia coli, GI87081896, Length=464, Percent_Identity=37.7155172413793, Blast_Score=307, Evalue=8e-85, Organism=Escherichia coli, GI1787715, Length=476, Percent_Identity=36.7647058823529, Blast_Score=286, Evalue=2e-78, Organism=Escherichia coli, GI1787684, Length=481, Percent_Identity=31.1850311850312, Blast_Score=239, Evalue=4e-64, Organism=Escherichia coli, GI87081926, Length=461, Percent_Identity=30.1518438177874, Blast_Score=201, Evalue=9e-53, Organism=Escherichia coli, GI1788042, Length=474, Percent_Identity=29.535864978903, Blast_Score=175, Evalue=6e-45, Organism=Escherichia coli, GI1787250, Length=466, Percent_Identity=25.9656652360515, Blast_Score=127, Evalue=1e-30, Organism=Escherichia coli, GI1787653, Length=301, Percent_Identity=25.9136212624585, Blast_Score=75, Evalue=1e-14, Organism=Caenorhabditis elegans, GI25144435, Length=466, Percent_Identity=40.7725321888412, Blast_Score=359, Evalue=1e-99, Organism=Caenorhabditis elegans, GI17562198, Length=480, Percent_Identity=39.7916666666667, Blast_Score=358, Evalue=3e-99, Organism=Caenorhabditis elegans, GI133930964, Length=485, Percent_Identity=37.7319587628866, Blast_Score=337, Evalue=1e-92, Organism=Caenorhabditis elegans, GI25143876, Length=486, Percent_Identity=36.8312757201646, Blast_Score=327, Evalue=1e-89, Organism=Caenorhabditis elegans, GI32564736, Length=420, Percent_Identity=40.4761904761905, Blast_Score=326, Evalue=1e-89, Organism=Caenorhabditis elegans, GI25143874, Length=486, Percent_Identity=36.8312757201646, Blast_Score=326, Evalue=2e-89, Organism=Caenorhabditis elegans, GI17551164, Length=481, Percent_Identity=37.4220374220374, Blast_Score=318, Evalue=6e-87, Organism=Caenorhabditis elegans, GI71995606, Length=485, Percent_Identity=33.6082474226804, Blast_Score=288, Evalue=5e-78, Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=33.729216152019, Blast_Score=251, Evalue=8e-67, Organism=Caenorhabditis elegans, GI17534119, Length=473, Percent_Identity=32.1353065539112, Blast_Score=242, Evalue=3e-64, Organism=Caenorhabditis elegans, GI71986308, Length=442, Percent_Identity=31.447963800905, Blast_Score=191, Evalue=7e-49, Organism=Caenorhabditis elegans, GI115534176, Length=488, Percent_Identity=25.8196721311475, Blast_Score=171, Evalue=1e-42, Organism=Caenorhabditis elegans, GI32566756, Length=443, Percent_Identity=28.4424379232506, Blast_Score=143, Evalue=2e-34, Organism=Caenorhabditis elegans, GI25146391, Length=444, Percent_Identity=28.3783783783784, Blast_Score=143, Evalue=2e-34, Organism=Caenorhabditis elegans, GI25146394, Length=444, Percent_Identity=28.3783783783784, Blast_Score=143, Evalue=3e-34, Organism=Caenorhabditis elegans, GI17534447, Length=485, Percent_Identity=26.1855670103093, Blast_Score=138, Evalue=7e-33, Organism=Caenorhabditis elegans, GI17564084, Length=357, Percent_Identity=30.812324929972, Blast_Score=134, Evalue=1e-31, Organism=Caenorhabditis elegans, GI32564151, Length=445, Percent_Identity=26.5168539325843, Blast_Score=127, Evalue=2e-29, Organism=Caenorhabditis elegans, GI115532534, Length=341, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=6e-29, Organism=Caenorhabditis elegans, GI71990744, Length=323, Percent_Identity=25.3869969040248, Blast_Score=84, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6324950, Length=474, Percent_Identity=38.1856540084388, Blast_Score=333, Evalue=4e-92, Organism=Saccharomyces cerevisiae, GI6320917, Length=484, Percent_Identity=38.0165289256198, Blast_Score=330, Evalue=4e-91, Organism=Saccharomyces cerevisiae, GI6325196, Length=481, Percent_Identity=37.2141372141372, Blast_Score=317, Evalue=2e-87, Organism=Saccharomyces cerevisiae, GI6323822, Length=468, Percent_Identity=36.965811965812, Blast_Score=309, Evalue=5e-85, Organism=Saccharomyces cerevisiae, GI6323821, Length=468, Percent_Identity=35.8974358974359, Blast_Score=301, Evalue=2e-82, Organism=Saccharomyces cerevisiae, GI6319478, Length=483, Percent_Identity=35.1966873706004, Blast_Score=285, Evalue=1e-77, Organism=Saccharomyces cerevisiae, GI6321828, Length=507, Percent_Identity=26.4299802761341, Blast_Score=157, Evalue=4e-39, Organism=Saccharomyces cerevisiae, GI6321826, Length=505, Percent_Identity=25.5445544554455, Blast_Score=108, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6323757, Length=359, Percent_Identity=27.5766016713092, Blast_Score=92, Evalue=1e-19, Organism=Drosophila melanogaster, GI20129399, Length=480, Percent_Identity=43.3333333333333, Blast_Score=381, Evalue=1e-106, Organism=Drosophila melanogaster, GI24585660, Length=482, Percent_Identity=37.7593360995851, Blast_Score=334, Evalue=9e-92, Organism=Drosophila melanogaster, GI281362580, Length=476, Percent_Identity=36.344537815126, Blast_Score=321, Evalue=8e-88, Organism=Drosophila melanogaster, GI62472918, Length=476, Percent_Identity=36.344537815126, Blast_Score=321, Evalue=8e-88, Organism=Drosophila melanogaster, GI62472926, Length=476, Percent_Identity=36.344537815126, Blast_Score=321, Evalue=8e-88, Organism=Drosophila melanogaster, GI62472936, Length=476, Percent_Identity=36.344537815126, Blast_Score=321, Evalue=8e-88, Organism=Drosophila melanogaster, GI21356737, Length=476, Percent_Identity=36.344537815126, Blast_Score=321, Evalue=8e-88, Organism=Drosophila melanogaster, GI24650465, Length=471, Percent_Identity=39.7027600849257, Blast_Score=320, Evalue=1e-87, Organism=Drosophila melanogaster, GI24638878, Length=439, Percent_Identity=30.9794988610478, Blast_Score=177, Evalue=1e-44, Organism=Drosophila melanogaster, GI24638876, Length=439, Percent_Identity=30.9794988610478, Blast_Score=177, Evalue=1e-44, Organism=Drosophila melanogaster, GI24666674, Length=474, Percent_Identity=26.5822784810127, Blast_Score=177, Evalue=1e-44, Organism=Drosophila melanogaster, GI24668425, Length=454, Percent_Identity=25.9911894273128, Blast_Score=145, Evalue=4e-35, Organism=Drosophila melanogaster, GI24668417, Length=454, Percent_Identity=25.9911894273128, Blast_Score=145, Evalue=4e-35, Organism=Drosophila melanogaster, GI24668413, Length=454, Percent_Identity=25.9911894273128, Blast_Score=145, Evalue=4e-35, Organism=Drosophila melanogaster, GI281360299, Length=355, Percent_Identity=26.4788732394366, Blast_Score=106, Evalue=3e-23, Organism=Drosophila melanogaster, GI281360297, Length=355, Percent_Identity=26.4788732394366, Blast_Score=106, Evalue=3e-23, Organism=Drosophila melanogaster, GI281360295, Length=355, Percent_Identity=26.4788732394366, Blast_Score=106, Evalue=3e-23, Organism=Drosophila melanogaster, GI24586250, Length=355, Percent_Identity=26.4788732394366, Blast_Score=106, Evalue=3e-23, Organism=Drosophila melanogaster, GI281360301, Length=355, Percent_Identity=26.4788732394366, Blast_Score=106, Evalue=4e-23, Organism=Drosophila melanogaster, GI45552499, Length=356, Percent_Identity=25.8426966292135, Blast_Score=104, Evalue=2e-22, Organism=Drosophila melanogaster, GI281360303, Length=356, Percent_Identity=25.8426966292135, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI28571802, Length=494, Percent_Identity=22.4696356275304, Blast_Score=83, Evalue=4e-16, Organism=Drosophila melanogaster, GI28571800, Length=494, Percent_Identity=22.4696356275304, Blast_Score=83, Evalue=4e-16, Organism=Drosophila melanogaster, GI28571806, Length=494, Percent_Identity=22.4696356275304, Blast_Score=83, Evalue=4e-16, Organism=Drosophila melanogaster, GI28571798, Length=494, Percent_Identity=22.4696356275304, Blast_Score=83, Evalue=4e-16, Organism=Drosophila melanogaster, GI28571796, Length=494, Percent_Identity=22.4696356275304, Blast_Score=83, Evalue=4e-16, Organism=Drosophila melanogaster, GI28571794, Length=494, Percent_Identity=22.4696356275304, Blast_Score=83, Evalue=4e-16, Organism=Drosophila melanogaster, GI28574525, Length=466, Percent_Identity=22.3175965665236, Blast_Score=80, Evalue=4e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016161 - InterPro: IPR016163 - InterPro: IPR016160 - InterPro: IPR016162 - InterPro: IPR015590 - InterPro: IPR011985 [H]
Pfam domain/function: PF00171 Aldedh [H]
EC number: 1.2.1.60
Molecular weight: Translated: 53100; Mature: 53100
Theoretical pI: Translated: 6.33; Mature: 6.33
Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQAVAAAKEAFPKWADLPM CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCH KERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNG HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCC KTYPVDDKMLNYTLVQPVGVCALASPWNVPFMTATWKVAPCLALGNTAVLKMSELSPLTA CCCCCCCHHHCEEEECCCCCEEECCCCCCCEEEECCCHHHHHEECCCEEEEECCCCCCCH DRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCCCE YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAE EHHHCCCCCCEEEEECCCHHHHHHHHHHHHEECCCCEECCCCEEEEEHHHHHHHHHHHHH RANRLRVGDPNDPNTQVRALISQQHWEKVSGYIRLGIEEGATLLAGGPDKPSDLPAHLKG HHCCEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCCCCCCCCC GNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGLRLANDVEYGLASYIWTQDVS CCEECCHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHH KVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD HHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC HPIPKWGV CCCCCCCC >Mature Secondary Structure MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQAVAAAKEAFPKWADLPM CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCH KERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNG HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCC KTYPVDDKMLNYTLVQPVGVCALASPWNVPFMTATWKVAPCLALGNTAVLKMSELSPLTA CCCCCCCHHHCEEEECCCCCEEECCCCCCCEEEECCCHHHHHEECCCEEEEECCCCCCCH DRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCCCE YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAE EHHHCCCCCCEEEEECCCHHHHHHHHHHHHEECCCCEECCCCEEEEEHHHHHHHHHHHHH RANRLRVGDPNDPNTQVRALISQQHWEKVSGYIRLGIEEGATLLAGGPDKPSDLPAHLKG HHCCEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCCCCCCCCC GNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGLRLANDVEYGLASYIWTQDVS CCEECCHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHH KVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD HHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC HPIPKWGV CCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+
Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7737515 [H]