Click here to switch to the map view.

The map label for this gene is sorA

Identifier: 30064702

GI number: 30064702

Start: 3521323

End: 3522063

Strand: Direct

Name: sorA

Synonym: S3640

Alternate gene names: 30064702

Gene position: 3521323-3522063 (Clockwise)

Preceding gene: 30064701

Following gene: 30064703

Centisome position: 76.56

GC content: 54.93

Gene sequence:

>741_bases
ATGGGCAGCGTGCTGGATGAATTTCAGACTCATCGCCCGTTAATTGCCTGTACGGTGATTGGTTTAATTCTCGGTGATTT
AAAAACCGGAATAATACTCGGCGGTACGCTGGAATTGATAGCTCTCTGCTGGATGAACGTCGGCGCGGCGCAATCTCCGG
ATTCTGCACTCGCCAGCATAATCTCCGCCATTCTGGTTATCGTTGGTCAGCAAAGCATCGCCACCGGAATCGCCATCGCG
TTGCCTGTGGCTGCGGCAGGCCAGGTGCTGACGGTGTTTGCCCGTACCATCACCGTAGTGTTCCAGCACGCGGCGGATAA
AGCAGCAGAAGAGGCGCGGTTTCGCACTCTCGATATTCTGCATGTCTCCGCGCTTGGCGTGCAGGCGCTGCGCGTCGCCA
TTCCGGCACTGATTGTCTCACTGTTCGTCAGCGCCGATATGGTCAGCAATATGTTAAACGCCATTCCCGAATTTGTGACC
CGAGGACTACAGATTGCTGGCGGTTTTATCGTGGTGGTCGGTTACGCCATGGTGCTACGTATGATGGGCGTGAAATATTT
GATGCCTTTCTTTTTCCTCGGTTTCCTCGCAGGTGGCTACCTCGATCTCAGCCTGCTGGCGTTCGGTGGCGTCGGCGTGA
TCATGGCCCTGGTCTACATCCAGCTAAATCCACAGTGGTGTAAAGCTGAACCTCAACTCCAGGCCACCGCCTCCACCGCC
CTTGACCAACTTGACGATTAA

Upstream 100 bases:

>100_bases
GCTTTAACAGGCAGGGATGACGACACTTAAAAGGTGACAAATCATGGAAATAAGTACCCTACAAATCATTGCTATATTTC
TTTTTTCCTGTATTGCCGGA

Downstream 100 bases:

>100_bases
CGGAGCCATCATGGAACAGAGAAAAATTACACGCAGCGATCTGGTGAGCATGTTTCTGCGCTCCAACCTGCAACAGGCGT
CCTTTAACTTTGAACGTATT

Product: putative sorbose-permease PTS system IIC component

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MGSVLDEFQTHRPLIACTVIGLILGDLKTGIILGGTLELIALCWMNVGAAQSPDSALASIISAILVIVGQQSIATGIAIA
LPVAAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDILHVSALGVQALRVAIPALIVSLFVSADMVSNMLNAIPEFVT
RGLQIAGGFIVVVGYAMVLRMMGVKYLMPFFFLGFLAGGYLDLSLLAFGGVGVIMALVYIQLNPQWCKAEPQLQATASTA
LDQLDD

Sequences:

>Translated_246_residues
MGSVLDEFQTHRPLIACTVIGLILGDLKTGIILGGTLELIALCWMNVGAAQSPDSALASIISAILVIVGQQSIATGIAIA
LPVAAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDILHVSALGVQALRVAIPALIVSLFVSADMVSNMLNAIPEFVT
RGLQIAGGFIVVVGYAMVLRMMGVKYLMPFFFLGFLAGGYLDLSLLAFGGVGVIMALVYIQLNPQWCKAEPQLQATASTA
LDQLDD
>Mature_245_residues
GSVLDEFQTHRPLIACTVIGLILGDLKTGIILGGTLELIALCWMNVGAAQSPDSALASIISAILVIVGQQSIATGIAIAL
PVAAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDILHVSALGVQALRVAIPALIVSLFVSADMVSNMLNAIPEFVTR
GLQIAGGFIVVVGYAMVLRMMGVKYLMPFFFLGFLAGGYLDLSLLAFGGVGVIMALVYIQLNPQWCKAEPQLQATASTAL
DQLDD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=247, Percent_Identity=62.3481781376518, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1789528, Length=195, Percent_Identity=29.7435897435897, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 25887; Mature: 25756

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCC
>Mature Secondary Structure 
GSVLDEFQTHRPLIACTVIGLILGDLKTGIILGGTLELIALCWMNVGAAQSPDSALASI
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCEEECHHHHHHHHHHHCCCCCCCCHHHHHHH
ISAILVIVGQQSIATGIAIALPVAAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDIL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVSALGVQALRVAIPALIVSLFVSADMVSNMLNAIPEFVTRGLQIAGGFIVVVGYAMVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
MMGVKYLMPFFFLGFLAGGYLDLSLLAFGGVGVIMALVYIQLNPQWCKAEPQLQATASTA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHH
LDQLDD
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]