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The map label for this gene is yfcG

Identifier: 30063728

GI number: 30063728

Start: 2408190

End: 2408837

Strand: Direct

Name: yfcG

Synonym: S2513

Alternate gene names: 30063728

Gene position: 2408190-2408837 (Clockwise)

Preceding gene: 161486459

Following gene: 30063729

Centisome position: 52.36

GC content: 50.93

Gene sequence:

>648_bases
ATGATCGATCTCTATTTCGCCCCGACACCCAATGGTCACAAAATTACGCTGTTTCTCGAAGAAGCAGAGCTTGATTATCG
CTTGATTAAGGTAGACTTGGGGAAAGGCGGTCAGTTTCGTCCGGAATTTTTGCGCATTTCGCCCAACAACAAAATTCCGG
CAATTGTTGATCATTCTCCTGCCGATGGCGGCGAACCGTTAAGCCTCTTTGAGTCTGCTGCCATTTTGTTGTATCTGGCT
GAGAAAACAGGACTCTTTTTGAGTCATGAAACGCGTGAGCGCGCCGCCACATTACAGTGGTTATTCTGGCAGGTAGGCGG
ACTGGGGCCGATGCTTGGGCAAAATCATCATTTTAATCACGCAGCCCCCCAAACCATTCCTTACGCTATTGAACGTTATC
AGGTTGAAACTCAGCGTCTTTACCATGTACTAAACAAGCGGCTGGAAAACTCGCCCTGGCTGGGAGGCGAGAACTACAGC
ATTGCGGATATTGCCTGCTGGCCGTGGGTTAATGCCTGGACTCGCCTGCGAATTGACCTCGCAATGTATCCGGCAGTCAA
GAACTGGCATGAGCGGATCCGTTCGCGCCCTGCCACCGGGCAGGCACTGCTAAAAGCACAACTCGGTGATGAGCGTTCGG
ATAGTTAA

Upstream 100 bases:

>100_bases
CTATAGAGCCTTTTTGTCACTGTCACGTGACGAATACTCACGTAAGTCGCCGCGCTTTCTATACTTGTGGTGTTCAGATG
ATTAAACAACCGGAGCTGCA

Downstream 100 bases:

>100_bases
CAGAAACAGGTTCTCGTGTATTATTTCATCCTAAGTAAAACAACGGAGAACCTGCAATGGCACAACCTGCCGCTATTATT
CGTATAAAGAACCTTCGTTT

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSPADGGEPLSLFESAAILLYLA
EKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
IADIACWPWVNAWTRLRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS

Sequences:

>Translated_215_residues
MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSPADGGEPLSLFESAAILLYLA
EKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
IADIACWPWVNAWTRLRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS
>Mature_215_residues
MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSPADGGEPLSLFESAAILLYLA
EKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
IADIACWPWVNAWTRLRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=215, Percent_Identity=99.0697674418605, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=40.6542056074766, Blast_Score=149, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324100, Length=233, Percent_Identity=33.4763948497854, Blast_Score=119, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28571670, Length=164, Percent_Identity=28.0487804878049, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864598, Length=207, Percent_Identity=28.5024154589372, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864592, Length=201, Percent_Identity=25.8706467661692, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI85725204, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737923, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646249, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17864594, Length=195, Percent_Identity=25.1282051282051, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45549270, Length=201, Percent_Identity=24.8756218905473, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17933730, Length=193, Percent_Identity=25.9067357512953, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24515; Mature: 24515

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSP
CEEEEECCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEECCC
ADGGEPLSLFESAAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNH
CCCCCCHHHHHHHEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAWTRLRIDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEE
AMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS
EECHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSP
CEEEEECCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEECCC
ADGGEPLSLFESAAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNH
CCCCCCHHHHHHHEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAWTRLRIDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEE
AMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS
EECHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]