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The map label for this gene is yeiL

Identifier: 30063604

GI number: 30063604

Start: 2257238

End: 2257816

Strand: Direct

Name: yeiL

Synonym: S2377

Alternate gene names: 30063604

Gene position: 2257238-2257816 (Clockwise)

Preceding gene: 30063601

Following gene: 30063611

Centisome position: 49.08

GC content: 43.52

Gene sequence:

>579_bases
ATGAGTGAATCTGCGTTTAAGGATTGCTTTTCAACGGATGTTTCAGCCGATACGCGGCTGTTTCATTTTTTAGCGCGTGA
CTACATTGTGCAGGAAGGGCAACAGCCGTCATGGCTGTTTTATCTGACGCGAGGCCGCGCCAGGCTTTACGCCACGCTTG
CCAATGGTCGCGTGTCGCTGATCGATTTCTTTGCCGCTCCCTGTTTTATTGGCGAGATTGAGTTAATCGACAAAGACCAT
GAACCGCGTGCGGTGCAGGCTATTGAAGAGTGTTGGTGCCTTGCGCTCCCTATGAAACATTACCGTCCGCTGTTATTAAA
CGACACCCTATTTTTACGAAAACTTTGCGTCACCTTAAGTCATAAAAATTATCGTAATATTGTTTCTTTAACTCAGAATC
AATCATTTCCGTTAGTGAATCGCCTGGCAGCATTTATATTACTCTCACAAGAAGGTGATCTTTATCACGAAAAGCATACG
CAAGCGGCAGAGTATTTAGGCGTTTCTTATCGACATCTTTTATATGTTCTCGCGCAATTCATTCACGACGGTTTATTAAT
TAAAAGAAAGGATATCTAA

Upstream 100 bases:

>100_bases
TTGAATCTTAACAACAGCGTACGTATGCTAAATATGAGAAATCTCATAGCGGATAAACATCGTGAAAGAAATCCACAATA
ATGACCTTAAGCAGCAATTG

Downstream 100 bases:

>100_bases
TTAAAAACAGAAAGCAGTTGTCAGGACTGGCGCTGGAGATGGACCCGGAGAATAAATTCTCCGGGATGATGCAGTAAAAA
TTATTTGCAATAGCGCGATT

Product: DNA-binding transcriptional activator YeiL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDH
EPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHT
QAAEYLGVSYRHLLYVLAQFIHDGLLIKRKDI

Sequences:

>Translated_192_residues
MSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDH
EPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHT
QAAEYLGVSYRHLLYVLAQFIHDGLLIKRKDI
>Mature_191_residues
SESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDHE
PRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQ
AAEYLGVSYRHLLYVLAQFIHDGLLIKRKDI

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=190, Percent_Identity=98.9473684210526, Blast_Score=391, Evalue=1e-110,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 22256; Mature: 22125

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYATLANGRVSL
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCHH
IDFFAAPCFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLS
HHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHC
HKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQF
CCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
IHDGLLIKRKDI
HHCCEEEEECCC
>Mature Secondary Structure 
SESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYATLANGRVSL
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCHH
IDFFAAPCFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLS
HHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHC
HKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQF
CCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
IHDGLLIKRKDI
HHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]