Click here to switch to the map view.

The map label for this gene is yedV

Identifier: 30063406

GI number: 30063406

Start: 2015585

End: 2016943

Strand: Reverse

Name: yedV

Synonym: S2112

Alternate gene names: 30063406

Gene position: 2016943-2015585 (Counterclockwise)

Preceding gene: 30063407

Following gene: 161486470

Centisome position: 43.85

GC content: 39.44

Gene sequence:

>1359_bases
ATGAAAAGATTATCTATAACCGTCCGTTTAACCTTGCTTTTTATATTTCTGCAGTCTGTTGCTGGCGCTGGAATTGTATG
GACTCTCTATAATGGCCTGGCAAGTGAGTTGAAATGGCGCGATGATACAACACTCATTAACCGGACAGCGCAGATCAAGC
AGTTGTTAATTGATGGGGTAAATCCAGATACGTTACCTGTGTACTTTAACCGGATGATGGATGTTAGTCAGGATATTTTG
ATCATTCATAGTGATGGCATCAATAAAATTGTTAACCGGACAAATGTCAGTGATGACATGTTAAATAACATACCTGCTAG
TGAGACAATCAGCGCAGCAGGCATTTACAGAAGCATTATTAATGATACAGAGATAGATGCTTTACGAATTAACATTGATG
AAGTTTCGCCATCATTAACGGTTACTGTGGCTAAATTGGCTTCAGCCAGACATAATATGCTTGAACAGTATAAAATTAAT
AGCATTATAATTTGCATTGTCGCCATTATACTGTGCTCAGTATTAAGTCCGTTGTTAATCAGGACGGGGGTGCGAGAGAT
CAAAAAGTTGAGTGGCGTAACGGAAGCGCTGAATTATAACGATAGCCGAGTGCCGGTTGAGGTTAACGCATTACCGAGAG
AACTAAAACCTCTTGGGCAGGCGTTGAATAAAATGCATCATGCTTTAGTCAAAGATTTTGAGCGCCTTAGTCAATTTGCT
GACGATCTCGCTCATGAACTTAGAACGCCAATTAATGCATTACTGGGTCAGAATCAGGTTACGCTCAGTCAAATCAGAAG
TATCGCTGAATATCAAAAAACAATTGCCGGAAACATTGAAGAGCTGGAAAATATTTCGCGGTTAACAGAGAATATACTGT
TTCTTGCCAGGGCAGACAAAAACAATGTTTTGGTGAAACTGGATTCGCTTTCTCTCAATAAGGAAGTTGAAAATCTTTTG
GACTATCTTGAATATCTTTCAGACGAGAAAGAGATTTGCTTTAAGGTCAAGTGCAATCAACAAATCTTTGCGGATAAAAT
TTTACTGCAACGAATGTTATCGAATCTTATTGTTAACGCCATTCGATATTCACCAGAAAAATCGCGTATTCATATAACCA
GTTTTCTTGATGCCAACGGCTCTCTTAATATTGATATCGCCAGTCCTGGAACGAAAATTAATGAGCCTGAAAAACTCTTC
CGTAGATTTTGGCGGGGAGATAATTCGCGTCATTCCGTAGGTCAGGGACTTGGCCTTTCTTTAGTCAAAGCGATTGCCGA
ATTACATGGAGGAAGTGCTACGTATCACTATCTCAGTAAGCATAACGTGTTCCGAATTACGTTACCGCAAAGAAATTAA

Upstream 100 bases:

>100_bases
CCATTCGCAGGCTCCGCGCAAAAGTTGATGATCCTTTTCCTGAAAAGCTAATCGCCACAATCCGGGGGATGGGCTATTCA
TTCGTAGCGGTAAAAAAATA

Downstream 100 bases:

>100_bases
CATCGGGCTTCAGTACGCCATAAGTTAACCGTGAAAAAACGCAGCCACGTCGTGAGTATTAACGTGGCTGCGATTGATTA
TGCGCTTACATCACAATGTA

Product: putative 2-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKRLSITVRLTLLFIFLQSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDIL
IIHSDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
SIIICIVAIILCSVLSPLLIRTGVREIKKLSGVTEALNYNDSRVPVEVNALPRELKPLGQALNKMHHALVKDFERLSQFA
DDLAHELRTPINALLGQNQVTLSQIRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLL
DYLEYLSDEKEICFKVKCNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLF
RRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQRN

Sequences:

>Translated_452_residues
MKRLSITVRLTLLFIFLQSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDIL
IIHSDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
SIIICIVAIILCSVLSPLLIRTGVREIKKLSGVTEALNYNDSRVPVEVNALPRELKPLGQALNKMHHALVKDFERLSQFA
DDLAHELRTPINALLGQNQVTLSQIRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLL
DYLEYLSDEKEICFKVKCNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLF
RRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQRN
>Mature_452_residues
MKRLSITVRLTLLFIFLQSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDIL
IIHSDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
SIIICIVAIILCSVLSPLLIRTGVREIKKLSGVTEALNYNDSRVPVEVNALPRELKPLGQALNKMHHALVKDFERLSQFA
DDLAHELRTPINALLGQNQVTLSQIRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLL
DYLEYLSDEKEICFKVKCNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLF
RRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQRN

Specific function: Probable member of a two-component regulatory system yedW/yedV. May activate yedW by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788279, Length=452, Percent_Identity=96.6814159292035, Blast_Score=872, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=296, Percent_Identity=33.7837837837838, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=30.2325581395349, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789403, Length=451, Percent_Identity=27.0509977827051, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=24.6323529411765, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=26.9565217391304, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790551, Length=292, Percent_Identity=27.7397260273973, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787894, Length=277, Percent_Identity=28.158844765343, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789149, Length=213, Percent_Identity=25.8215962441315, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=26.4227642276423, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=24.8888888888889, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50802; Mature: 50802

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLSITVRLTLLFIFLQSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGV
CCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
NPDTLPVYFNRMMDVSQDILIIHSDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSII
CCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
NDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKINSIIICIVAIILCSVLSPLLI
CCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGVREIKKLSGVTEALNYNDSRVPVEVNALPRELKPLGQALNKMHHALVKDFERLSQFA
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDLAHELRTPINALLGQNQVTLSQIRSIAEYQKTIAGNIEELENISRLTENILFLARADK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECC
NNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICFKVKCNQQIFADKILLQRMLSNLIVNA
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
IRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLS
HHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHH
LVKAIAELHGGSATYHYLSKHNVFRITLPQRN
HHHHHHHHCCCCCEEEEECCCCEEEEECCCCC
>Mature Secondary Structure
MKRLSITVRLTLLFIFLQSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGV
CCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
NPDTLPVYFNRMMDVSQDILIIHSDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSII
CCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
NDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKINSIIICIVAIILCSVLSPLLI
CCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGVREIKKLSGVTEALNYNDSRVPVEVNALPRELKPLGQALNKMHHALVKDFERLSQFA
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDLAHELRTPINALLGQNQVTLSQIRSIAEYQKTIAGNIEELENISRLTENILFLARADK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECC
NNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICFKVKCNQQIFADKILLQRMLSNLIVNA
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
IRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLS
HHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHH
LVKAIAELHGGSATYHYLSKHNVFRITLPQRN
HHHHHHHHCCCCCEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]