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The map label for this gene is insK [C]

Identifier: 30062428

GI number: 30062428

Start: 929611

End: 930498

Strand: Direct

Name: insK [C]

Synonym: S0949

Alternate gene names: 30062428

Gene position: 929611-930498 (Clockwise)

Preceding gene: 30062427

Following gene: 30062429

Centisome position: 20.21

GC content: 54.05

Gene sequence:

>888_bases
ATGCCACTGCTGGATAAGCTGCGTGAGCAGTACAGGGTCGGACCGCTATGCAGCGAACTGCATATTGCCCCGTCAACGTA
TTACCACTGTCAGCAACAGCGACATCATCCGGATAAACGCAGTGCCCGTGCGCAGCGCGATGACTGGCTGAAGAAAGAGA
TACAGCGCGTATACGATGAAAATCACAAGGTATACGGTGTGCGTAAAGTCTGGCGTCAGTTGTTACGGGAAGGTATCAGA
GTGGCCAGATGCACTGTGGCACGTCTCATGGAGGTTATGGGACTTGCCGGTGTTCTCCGGGGTAAAAAGGTCCGTACGAC
CATCAGCCGGAAAGCCGTTGCCGCAGGCGACCGCGTAAACCGTCAGTTCGTGGCAGAACGACCTGACCAGCTGTGGGTGG
CTGATTTTACTTACGTCAGCACATGGCAGGGCTTCGTCTATGTGGCGTTCATCATTGATGTGTTTGCCGGATACATCGTG
GGGTGGCGGGTCTCATCGTCCATGGAAACGACATTCGTGCTGGATGCACTGGAGCAGGCGTTATGGGCCCGTCGACCGTC
CGGCACGGTCCATCACAGTGATAAAGGTTCTCAGTATGTATCGCTGGCCTACACACAGCGGCTTAAGGAAGCCGGATTAC
TGGCATCAACAGGAAGTACAGGCGACTCGTATGACAACGCGATGGCGGAGAGCATCAATGGTCTTTACAAAGCGGAGGTA
ATACACCGTAAGAGCTGGAAAAACCGTGCAGAAGTGGAACTGGCCACACTCACGTGGGTGGACTGGTATAACAATCGACG
ATTGCTGGAAAGGCTGGGCCACATCCCTCCGGCAGAAGCAGAAAAAGCTTATTATGCTTCCATCGGAAACGATGATCTGG
CAGCCTGA

Upstream 100 bases:

>100_bases
TGGAGCGTGAAAATCGTGAACTGCGCCGCAGTAACGATATCCTTCGCCAGGCTTCCGCTTATTTTGCGAAGGCGGAGTTC
GACCGCCTCTGGAAAAAATG

Downstream 100 bases:

>100_bases
GTTCACAGATAAAACACTCTCCAGGAAACCCGGGGCGGTTCAGCTGGTCACCTGCAAACAGAACGAAGTGGAGCCGGAGG
ACTGGTTGCGCGAAGTGATC

Product: IS629 orfB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPLLDKLREQYRVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEIQRVYDENHKVYGVRKVWRQLLREGIR
VARCTVARLMEVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAEV
IHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHIPPAEAEKAYYASIGNDDLAA

Sequences:

>Translated_295_residues
MPLLDKLREQYRVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEIQRVYDENHKVYGVRKVWRQLLREGIR
VARCTVARLMEVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAEV
IHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHIPPAEAEKAYYASIGNDDLAA
>Mature_294_residues
PLLDKLREQYRVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEIQRVYDENHKVYGVRKVWRQLLREGIRV
ARCTVARLMEVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIVG
WRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAEVI
HRKSWKNRAEVELATLTWVDWYNNRRLLERLGHIPPAEAEKAYYASIGNDDLAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=252, Percent_Identity=51.1904761904762, Blast_Score=248, Evalue=3e-66,
Organism=Escherichia coli, GI1789981, Length=286, Percent_Identity=30.0699300699301, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1788405, Length=292, Percent_Identity=27.3972602739726, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787263, Length=292, Percent_Identity=27.3972602739726, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786753, Length=292, Percent_Identity=27.3972602739726, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786570, Length=292, Percent_Identity=27.3972602739726, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786490, Length=292, Percent_Identity=27.3972602739726, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33819; Mature: 33688

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDKLREQYRVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEIQRVYDE
CCHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
NHKVYGVRKVWRQLLREGIRVARCTVARLMEVMGLAGVLRGKKVRTTISRKAVAAGDRVN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
RQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQA
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
LWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAEV
HHHCCCCCCCEECCCCCCEEHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
IHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHIPPAEAEKAYYASIGNDDLAA
HHHHHCCCCCCEEEEEEEEEHHHCCHHHHHHHCCCCCCCCCHHHEEECCCCCCCC
>Mature Secondary Structure 
PLLDKLREQYRVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEIQRVYDE
CHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
NHKVYGVRKVWRQLLREGIRVARCTVARLMEVMGLAGVLRGKKVRTTISRKAVAAGDRVN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
RQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQA
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
LWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAEV
HHHCCCCCCCEECCCCCCEEHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
IHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHIPPAEAEKAYYASIGNDDLAA
HHHHHCCCCCCEEEEEEEEEHHHCCHHHHHHHCCCCCCCCCHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]