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The map label for this gene is ybdR

Identifier: 30062066

GI number: 30062066

Start: 543827

End: 545065

Strand: Direct

Name: ybdR

Synonym: S0532

Alternate gene names: 30062066

Gene position: 543827-545065 (Clockwise)

Preceding gene: 30062064

Following gene: 30062067

Centisome position: 11.82

GC content: 50.44

Gene sequence:

>1239_bases
ATGAAAGCATTGACTTATCACGGCCCACATCACGTTCAGGTAGAAAATGTTCCCGATCCGGGCATTGAACAGGCAGATGA
TATTATTCTGCGTATTACGGTAACGGCGATCTGTGGCTCTGACCTCCATCTTTATCGAGGCAAAATACCCCAGGTTAAAC
ATGGCGATATTTTTGGTCATGAATTTATGGGGGAAGTCGTTGAAACCGGGAAGGACGTAAAAAATTTGCAAAAAGGCGAC
CGGGTGGTAATTCCGTTCGTCATTGCTTGTGGCGACTGTTTTTTCTGTCGATTACAGCAATATGCCGCCTGCGAAAATAC
CAATGCGGGTAAAGGCGCTGCGCTCAATAAAAAACAGATACCTGCTCCCGCGGCATTGTTTGGTTATAGTCACCTGTATG
GTGGCGTTCCTGGCGGGCAGGCGGAATATGTCCGCGTCCCGAAAGGGAATGTGGGGCCGTTTAAAGTACCGCCTTTGCTT
TCAGATGATAAAGCCCTTTTCCTTTCTGATATTCTGCCAACGGCATGGCAGGCAGCAAAAAATGTGCAGATCCAACAAGG
TTCAAGCGTTGCAGTCTATGGTGCTGGTCCTGTGGGATTGTTGACAATCGCCTGTGCACGGTTGCTCGGTGCGGAACAGA
TTTTTGTTGTTGATCATCATCCCTACCGCTTGCGTTTCGCCGCTGACCGCTACGGCGCGATCCCGATTAATTTCGATGAA
GATAGCGATCCGGCACAGTCAATTATTGAACAAACGGCAGGTCACCGGGGCGTGGATGCAGTAATAGACGCCGTCGGTTT
TGAAGCGAAAGGCAGCACCACGGAAACGGTGCTGACTAACCTGAAACTGGAGGGCAGCAGCGGTAAAGCGTTGCGCCAGT
GTATTGCGGCGGTCAGGCGTGGCGGCATTGTTAGCGTACCGGGCGTCTACGCTGGATTTATTCACGGTTTCCTGTTTGGC
GACGCCTTTGATAAAGGGTTGACGTTTAAAATGGGACAGACCCACGTTCACGCATGGCTGGGAGAATTATTACCGTTAAT
TGAGAAAGGATTACTGAAACCAGAAGAAATTGTTACCCACTATATGCCGTTTGAAGAGGCCGCCCGGGGATATGAGATTT
TCGAAAAACGTGAAGAGGAGTGCCGTAAGGTGATTCTGGTACCCGGTGCACAAAGCGCAGAGGCGGCGCAGAAGGCGGTT
TCAGGTCTGGTGAATGCGATGCCGGGGGGAACAATATGA

Upstream 100 bases:

>100_bases
ACACTAGGAATTCTCCCAAAACCTGCGGTACCGCCCGTTTTCCCGCTGTGATAGCTACCCTTAAAGACTGACTCTTTTTT
GAACTGTCTCTGGAGGTTGC

Downstream 100 bases:

>100_bases
TCGTCAGGAGTGGTTTTCGAGGTAAAGGACAGCCATGACGATAATCGCCGCCATAATCAGAAATCCTATCAGGATGTAAA
ATGCTTCTGCCATGGTTATT

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKALTYHGPHHVQVENVPDPGIEQADDIILRITVTAICGSDLHLYRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGD
RVVIPFVIACGDCFFCRLQQYAACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
SDDKALFLSDILPTAWQAAKNVQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVDHHPYRLRFAADRYGAIPINFDE
DSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTETVLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFG
DAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQSAEAAQKAV
SGLVNAMPGGTI

Sequences:

>Translated_412_residues
MKALTYHGPHHVQVENVPDPGIEQADDIILRITVTAICGSDLHLYRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGD
RVVIPFVIACGDCFFCRLQQYAACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
SDDKALFLSDILPTAWQAAKNVQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVDHHPYRLRFAADRYGAIPINFDE
DSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTETVLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFG
DAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQSAEAAQKAV
SGLVNAMPGGTI
>Mature_412_residues
MKALTYHGPHHVQVENVPDPGIEQADDIILRITVTAICGSDLHLYRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGD
RVVIPFVIACGDCFFCRLQQYAACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
SDDKALFLSDILPTAWQAAKNVQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVDHHPYRLRFAADRYGAIPINFDE
DSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTETVLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFG
DAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQSAEAAQKAV
SGLVNAMPGGTI

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI71565154, Length=250, Percent_Identity=31.2, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI156523966, Length=388, Percent_Identity=22.4226804123711, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4501939, Length=260, Percent_Identity=24.2307692307692, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI71565152, Length=365, Percent_Identity=24.1095890410959, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786825, Length=412, Percent_Identity=98.7864077669903, Blast_Score=835, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=400, Percent_Identity=28, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787863, Length=394, Percent_Identity=23.8578680203046, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI226510992, Length=367, Percent_Identity=26.4305177111717, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082125, Length=261, Percent_Identity=28.3524904214559, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790718, Length=216, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788407, Length=317, Percent_Identity=25.8675078864353, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788075, Length=381, Percent_Identity=25.4593175853018, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786552, Length=246, Percent_Identity=27.6422764227642, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081918, Length=255, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25146526, Length=276, Percent_Identity=25.3623188405797, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=276, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565904, Length=247, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320033, Length=405, Percent_Identity=26.4197530864197, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319258, Length=301, Percent_Identity=29.5681063122924, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319257, Length=296, Percent_Identity=29.3918918918919, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17737895, Length=209, Percent_Identity=26.7942583732057, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 44279; Mature: 44279

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALTYHGPHHVQVENVPDPGIEQADDIILRITVTAICGSDLHLYRGKIPQVKHGDIFGH
CCCEECCCCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCHHHCCCCCCCCCCCCCCH
EFMGEVVETGKDVKNLQKGDRVVIPFVIACGDCFFCRLQQYAACENTNAGKGAALNKKQI
HHHHHHHHCCHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLLSDDKALFLSDILPTAWQAAK
CCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHC
NVQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVDHHPYRLRFAADRYGAIPINFDE
CCEEECCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCEEECCCC
DSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTETVLTNLKLEGSSGKALRQCIAAVRR
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHHC
GGIVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTH
CCEEECCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YMPFEEAARGYEIFEKREEECRKVILVPGAQSAEAAQKAVSGLVNAMPGGTI
CCCHHHHHCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKALTYHGPHHVQVENVPDPGIEQADDIILRITVTAICGSDLHLYRGKIPQVKHGDIFGH
CCCEECCCCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCHHHCCCCCCCCCCCCCCH
EFMGEVVETGKDVKNLQKGDRVVIPFVIACGDCFFCRLQQYAACENTNAGKGAALNKKQI
HHHHHHHHCCHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLLSDDKALFLSDILPTAWQAAK
CCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHC
NVQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVDHHPYRLRFAADRYGAIPINFDE
CCEEECCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCEEECCCC
DSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTETVLTNLKLEGSSGKALRQCIAAVRR
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHHC
GGIVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTH
CCEEECCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YMPFEEAARGYEIFEKREEECRKVILVPGAQSAEAAQKAVSGLVNAMPGGTI
CCCHHHHHCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]