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The map label for this gene is gsk

Identifier: 30061977

GI number: 30061977

Start: 436347

End: 437651

Strand: Direct

Name: gsk

Synonym: S0429

Alternate gene names: 30061977

Gene position: 436347-437651 (Clockwise)

Preceding gene: 30061975

Following gene: 30061980

Centisome position: 9.49

GC content: 52.11

Gene sequence:

>1305_bases
ATGAAATTTCCCGGTAAACGTAAATCCAAACATTACTTCCCTGTAAATGCACGCGATCCGCTGCTTCAGCAATTCCAGCC
AGAAAACGAAACCAGCGCCGCCTGGGTCGTAGGTATTGACCAGACGCTGGTCGATATTGAAGCGAAAGTGGATGATGAAT
TCATTGAGCGTTATGGATTAAGCGCCGGGCATTCACTGGTGATTGAGGATGACGTAGCCGAAGTGCTTTATCAGGAGCTA
AAACAGAAAAACCTGATTACCCATCAGTTTGCGGGTGGCACCATTGGTAACACCATGCACAACTACTCGGTGCTCGCGGA
CGACCGTTCGGTGCTGCTGGGCGTCATGTGCAGCAATATTGAAATTGGCAGTTATGCCTATCGTTACCTGTGTAACACTT
CCAGCCGTACCGATCTTAACTATCTACAAGGCGTGGATGGTCCGATTGGTCGTTGCTTTACGCTGATTGGCGAGTCCGGG
GAACGTACCTTTGCTATCAGTCCAGGCCACATGAACCAGCTGCGGGCTGAAAGCATTCCGGAAGATGTGATTGCCGGAGC
CTCGGCACTGGTTCTCACCTCATATCTGGTGCGTTGCAAGCCGGGTGAACCCATGCCGGAAGCAACCATGAAAGCCATTG
AGTACGCGAAGAAATATAACGTACCGGTGGTGCTGACGCTGGGCACCAAGTTTGTCATTGCCGAGAATCCGCAGTGGTGG
CAGCAATTCCTCAAAGACCACGTTTCTATCCTTGCGATGAACGAAGATGAAGCCGAAGCGTTGACCGGAGAAAGCGATCC
GTTGTTGGCATCTGACAAGGCGCTGGACTGGGTAGAGCTGGTGCTGTGCACCGCCGGGCCAATCGGCTTGTATATGGCGG
GCTTTACCGAAGACGAAGCGAAACGTAAAACCCAGCATCCGCTGCTGCCGGGCGCTATAGCGGAATTCAACCAGTATGAG
TTTAGCCGCGCCATGCGCCACAAGGATTGCCAGAATCCGCTGCGTGTCTATTCGCACATTGCGCCGTACATGGGCGGGCC
GGAAAAAATCATGAACACTAATGGAGCGGGGGATGGCGCATTGGCAGCGTTGCTGCATGACATTACCGCCAACAGCTACC
ATCGTAGCAACGTACCAAACTCCAGCAAACATAAATTCACCTGGTTAACTTATTCATCGTTAGCGCAGGTGTGTAAATAT
GCTAACCGTGTGAGCTATCAGGTACTGAACCAGCATTCACCTCGTTTAACGCGCGGCTTGCCGGAGCGTGAAGACAGCCA
GGAAGAGTCTTACTGGGATCGTTAA

Upstream 100 bases:

>100_bases
TGCGATCCCGCCTGCTGATATTGAAACTGGCTGCGTCTCGCGCGCTCCCGTCAGATTGTGTTAACATTCGCCGCTCAGTT
AACCACCCGTAAAAACAACC

Downstream 100 bases:

>100_bases
GTTATCGTCGGTTCGTAGGCCAGATAAGGCGTTCACGCCGCATCTGGCATTTGGCTCTCGATGCCTGATGCGACGCTGGC
GCGTCTTATCATGCCTACAT

Product: inosine-guanosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLVDIEAKVDDEFIERYGLSAGHSLVIEDDVAEVLYQEL
KQKNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKKYNVPVVLTLGTKFVIAENPQWW
QQFLKDHVSILAMNEDEAEALTGESDPLLASDKALDWVELVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYE
FSRAMRHKDCQNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSQEESYWDR

Sequences:

>Translated_434_residues
MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLVDIEAKVDDEFIERYGLSAGHSLVIEDDVAEVLYQEL
KQKNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKKYNVPVVLTLGTKFVIAENPQWW
QQFLKDHVSILAMNEDEAEALTGESDPLLASDKALDWVELVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYE
FSRAMRHKDCQNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSQEESYWDR
>Mature_434_residues
MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLVDIEAKVDDEFIERYGLSAGHSLVIEDDVAEVLYQEL
KQKNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKKYNVPVVLTLGTKFVIAENPQWW
QQFLKDHVSILAMNEDEAEALTGESDPLLASDKALDWVELVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYE
FSRAMRHKDCQNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSQEESYWDR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=99.3087557603687, Blast_Score=906, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48506; Mature: 48506

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLVDIEAKVDDEFIERYGL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEHHHCCHHHHHHHCC
SAGHSLVIEDDVAEVLYQELKQKNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNI
CCCCEEEEEHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHCCEEEECCHHHHHHHHHCCE
EIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESGERTFAISPGHMNQLRAESIP
EECCHHHHHEECCCCCCCHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCC
EDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKKYNVPVVLTLGTKFVIAENPQWW
HHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
QQFLKDHVSILAMNEDEAEALTGESDPLLASDKALDWVELVLCTAGPIGLYMAGFTEDEA
HHHHHHHHEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEECCCCHHH
KRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPLRVYSHIAPYMGGPEKIMNTNGAGDGA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHH
LAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKYANRVSYQVLNQHSPRLTRGL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PEREDSQEESYWDR
CCCCCCCHHHCCCC
>Mature Secondary Structure
MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLVDIEAKVDDEFIERYGL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEHHHCCHHHHHHHCC
SAGHSLVIEDDVAEVLYQELKQKNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNI
CCCCEEEEEHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHCCEEEECCHHHHHHHHHCCE
EIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESGERTFAISPGHMNQLRAESIP
EECCHHHHHEECCCCCCCHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCC
EDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKKYNVPVVLTLGTKFVIAENPQWW
HHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
QQFLKDHVSILAMNEDEAEALTGESDPLLASDKALDWVELVLCTAGPIGLYMAGFTEDEA
HHHHHHHHEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEECCCCHHH
KRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPLRVYSHIAPYMGGPEKIMNTNGAGDGA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHH
LAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKYANRVSYQVLNQHSPRLTRGL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PEREDSQEESYWDR
CCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]