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The map label for this gene is ilvH

Identifier: 30061643

GI number: 30061643

Start: 84684

End: 85175

Strand: Direct

Name: ilvH

Synonym: S0075

Alternate gene names: 30061643

Gene position: 84684-85175 (Clockwise)

Preceding gene: 161486550

Following gene: 30061645

Centisome position: 1.84

GC content: 50.2

Gene sequence:

>492_bases
ATGCGCCGGATATTATCAGTCTTACTCGAAAATGAATCAGGCGCGTTATCCCGCGTGATTGGCCTTTTTTCCCAGCGAGG
CTACAACATTGAAAGCCTGACCGTTGCGCCAACCGACGATCCGACATTATCGCGTATGACCATCCAGACCGTGGGCGATG
AAAAAGTACTTGAGCAGATCGAAAAGCAATTACACAAGCTGGTCGATGTCTTGCGCGTGAGTGAGTTGGGGCAGGGCGCG
CATGTTGAGCGGGAAATCATGCTGGTGAAAATTCAGGCCAGCGGTTACGGGCGTGACGAAGTGAAACGTAATACGGAAAT
ATTCCGTGGGCAAATTATCGATGTCACCCCCTCGCTTTATACCGTTCAATTAGCAGGCACCAGCGATAAGCTTGATGCAT
TTTTAGCATCGATTCGCGATGTGGCGAAAATTGTGGAAGTTGCTCGCTCTGGTGTGGTCGGACTTTCGCGCGGCGATAAA
ATAATGCGTTGA

Upstream 100 bases:

>100_bases
TTGATGTTACCGTCGATGGCAGTGAGCACGTCTACCCGATGCAGATTCGCGGGGGCGGAATGGATGAAATGTGGTTAAGC
AAAACGGAGAGAACCTGATT

Downstream 100 bases:

>100_bases
GAATGATCTCAAGTGCGCAATTTGCAGCCCAACATGTCACGTTGGGCTTTTTTTGCGAAATCAGTGGGAACCTGGAATAA
AAGCAGTTGCCGCAGTTAAT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGA
HVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
IMR

Sequences:

>Translated_163_residues
MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGA
HVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
IMR
>Mature_163_residues
MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGA
HVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
IMR

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=163, Percent_Identity=99.3865030674847, Blast_Score=321, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=26.8292682926829, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18035; Mature: 18035

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQI
CHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHEEEEECCCHHHHHHH
EKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLY
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCEE
TVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDKIMR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQI
CHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHEEEEECCCHHHHHHH
EKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLY
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCEE
TVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDKIMR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]