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The map label for this gene is yfdE

Identifier: 161486456

GI number: 161486456

Start: 2469225

End: 2470409

Strand: Reverse

Name: yfdE

Synonym: S2575

Alternate gene names: 161486456

Gene position: 2470409-2469225 (Counterclockwise)

Preceding gene: 30063779

Following gene: 30063775

Centisome position: 53.71

GC content: 44.98

Gene sequence:

>1185_bases
GTGTCTTTTCACCTTCGGCTTTTTTCAAGGCATAAGCAAATGACAAATAATGAAAGCAAAGGGCCGTTTGAAGGCTTATT
AGTTATCGATATGACACATGTCCTTAATGGACCTTTCGGAACTCAACTTCTTTATAATATGGGCGCAAGGGTAATTAAAG
TTGAGCCACCAGGTCATGGTGATGATACCCGCACATTTGGTCCCTATGTGGATGGACAGTCACTCTATTACAGTTTTATT
AATCATGGCAAAGAGAGTGTGGTTCTTGATTTAAAGAATGATCACGATAAAAGTATATTTATAAATATGCTCAAACAAGC
TGATGTATTAGCTGAGAATTTTCGCCTAGGTACAATGGAAAAACTGGGGTTTTCATGGGAAAGGTTACAAGAAATCAACC
CGCGCCTCATATATGCTTCATCGTCAGGTTTCGGACATACCGGTCCGCTAAAAGATGCTCCTGCCTACGATACCATCATT
CAGGCAATGAGTGGGATAATGATGGAAACAGGGTACCCTGATGCTCCGCCAGTGCGTGTTGGTACCTCTCTTGCGGATCT
ATGCGGCGGTGTCTATTTATTCAGCGGAATAGTGAGTGCACTTTATGGCCGCGAAAAGAGCCAGAGAGGGGCGCATGTCG
ATATAGCGATGTTTGATGCCACGCTGAGTTTTCTGGAGCATGGTCTGATGGCATATATTGCGACAGGGAAGTCACCACAA
CGCCTGGGAAATCGCCATCCCTACATGGCACCTTTTGATGTTTTCGATACTCAGGATAAGCCGATTACGATTTGTTGTGG
TAATGACAAGCTTTTTTCTGCGTTATGCCAGGCACTGGAGCTTACGGAACTGGTTAATGATCCCCGATTTAGCAGCAATA
TTTTACGCGTACAAAACCAGGCTATTCTTAAACAATATATTGAGCGAACGTTAAAAACGCAGGCAGCTGAAGTTTGGTTA
GCCAAAATACATGAAGTTGGTGTGCCCGTCGCGCCGTTATTAAGTGTGGCTGAGGCCATTAATTTGCCACAAACTCAGGC
GAGAAATATGTTGATTGAAGCCGGAGGAATAATGATGCCGGGTAATCCGATAAAAATCAGCGGCTGCGCGGACCCGCATG
TTATGCCGGGAGCGGCAACGCTCGACCAGCATGGGGAACAAATTCGCCAGGAGTTCTCATCATAA

Upstream 100 bases:

>100_bases
GTGAGCGTACTGGGCTTTGTCGTCACGGCTCCCTTGTGGATTTATGTCAGTCGACTGGTTTCATAATTAATCATGTTATT
GATTTTACATAAATGCCGAA

Downstream 100 bases:

>100_bases
ATGTAAGATGTGCTGGTAAATAGCTCCCACATTAGAACATTGTGGGAGCCGCAATTTAGTCATTTTTCTGACAGAAAACA
GCAATCTCCTGGTCCAGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSFHLRLFSRHKQMTNNESKGPFEGLLVIDMTHVLNGPFGTQLLYNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFI
NHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRLGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTII
QAMSGIMMETGYPDAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQ
RLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWL
AKIHEVGVPVAPLLSVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS

Sequences:

>Translated_394_residues
MSFHLRLFSRHKQMTNNESKGPFEGLLVIDMTHVLNGPFGTQLLYNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFI
NHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRLGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTII
QAMSGIMMETGYPDAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQ
RLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWL
AKIHEVGVPVAPLLSVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS
>Mature_393_residues
SFHLRLFSRHKQMTNNESKGPFEGLLVIDMTHVLNGPFGTQLLYNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFIN
HGKESVVLDLKNDHDKSIFINMLKQADVLAENFRLGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQ
AMSGIMMETGYPDAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQR
LGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLA
KIHEVGVPVAPLLSVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=391, Percent_Identity=32.4808184143223, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI300863124, Length=339, Percent_Identity=33.9233038348083, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI13376042, Length=339, Percent_Identity=30.9734513274336, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI300863126, Length=391, Percent_Identity=29.4117647058824, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI266458393, Length=200, Percent_Identity=35, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI266458397, Length=200, Percent_Identity=35, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI42794625, Length=200, Percent_Identity=35, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI266456254, Length=200, Percent_Identity=35, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI266458395, Length=143, Percent_Identity=37.7622377622378, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI42822893, Length=143, Percent_Identity=37.7622377622378, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI87082093, Length=381, Percent_Identity=98.4251968503937, Blast_Score=780, Evalue=0.0,
Organism=Escherichia coli, GI1788717, Length=401, Percent_Identity=29.6758104738155, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786222, Length=364, Percent_Identity=24.4505494505494, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32564160, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115535051, Length=199, Percent_Identity=28.643216080402, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24648431, Length=324, Percent_Identity=32.4074074074074, Blast_Score=207, Evalue=9e-54,
Organism=Drosophila melanogaster, GI24585488, Length=324, Percent_Identity=28.7037037037037, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 43430; Mature: 43299

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFHLRLFSRHKQMTNNESKGPFEGLLVIDMTHVLNGPFGTQLLYNMGARVIKVEPPGHG
CCEEHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHCCCEEEEECCCCCC
DDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRLGTME
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHH
KLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPPVRV
HHCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCHH
GTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQ
CCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCHH
RLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQ
HHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AILKQYIERTLKTQAAEVWLAKIHEVGVPVAPLLSVAEAINLPQTQARNMLIEAGGIMMP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCEEEC
GNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFHLRLFSRHKQMTNNESKGPFEGLLVIDMTHVLNGPFGTQLLYNMGARVIKVEPPGHG
CEEHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHCCCEEEEECCCCCC
DDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRLGTME
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHH
KLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPPVRV
HHCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCHH
GTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQ
CCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCHH
RLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQ
HHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AILKQYIERTLKTQAAEVWLAKIHEVGVPVAPLLSVAEAINLPQTQARNMLIEAGGIMMP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCEEEC
GNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]