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The map label for this gene is nahA [H]

Identifier: 29349802

GI number: 29349802

Start: 5786139

End: 5787779

Strand: Reverse

Name: nahA [H]

Synonym: BT_4394

Alternate gene names: 29349802

Gene position: 5787779-5786139 (Counterclockwise)

Preceding gene: 29349804

Following gene: 29349801

Centisome position: 92.45

GC content: 44.67

Gene sequence:

>1641_bases
ATGAAAATCAAACATTTTCTACCCCTGCTATTGCTACTCGGTAGCAATGAGATGCTTACAGCACAAGAAATCGCTCTCAC
CCCACAACCGGCTCACCTTACCGTAAAAGACGGCCGCTTTGAGTTTGGCAACCAACTTAAAGCCAAAGTCACTCCTTATC
AGGGAGACAGCATCCGTATGGTCTTTGAATCATTCAAAAAGGAATTGCAAGAAGCAACCGGCATCAAGGTTTCATCTACT
CAAAAAGAAGCTAAAGCAAGGATTATCTTAGATTTGAATCCACAACTTCCCGCTGAAGCTTATAAGCTGAACGTCTCGAA
AAAACAAGTCCGGATCGAAGCCTCCCGTCCGGCAGGTTTCTATTATGCGCTACAAACGCTAAAGCAACTGATGCCCCGCA
ACGTAATGGCAGGCGTAGCAACGTCCGACCATTCACAATGGAGTCTCCCATCTGTCGAGATTGAAGATGCTCCCCGTTTC
GAATGGAGAGGTTTTATGCTGGACGAAGGCAGACATTTCTTCGGTAAAGATGAGATAAAACGAGTGATCGACATGATGGC
CATCTACAAAATGAATCGTTTCCACTGGCATCTGACAGAAGATCAAGGCTGGAGAATCGAAATAAAGAAATACCCCAAAC
TGACGGAGACAGGCGCATGGAGAAACAGCAAAGTACTTGCATACGGTGACGTGAAACCAGACGGTGAGCGTTATGGCGGC
TTTTATACTCAGAAAGATATCAAAGAAATCGTAGCGTATGCAAAGAAGAAATTTATAGAAATCATTCCCGAAATAGACAT
TCCGGGACATTCACAGGCAGCCGTTGCAGCTTATCCGGAGTTCTTGGCGTGCGACCCAAGGGATAAACATGAAGTATGGC
TACAACAAGGGATTTCTACTGATGTAATCAACGTAGCCAACCCGAAAGCGATGCAGTTTGCCAAAGAGGTAATTGATGAA
CTCACTGAATTGTTTCCATTCAATTATATTCATTTAGGCGGTGACGAATGCCCCACAAGGAAATGGCAAAAGAATGACGA
ATGCAAGAAGCTGCTGAGTGAAATAGGTTCTTCCAACTTCAGAGACTTGCAGATTTATTTCTACAAACAACTAAAAGATT
ACATTGCCACCAAACCTGCCGATCAACAACGCCAACTTATATTCTGGAACGAAGTGCTTCACGGAAATACCAGTATCCTT
GGCAATGACATCACCATTATGGCATGGATCGGAGCTAATGCCGCCGCAAAACAGGCTGCCAAGCAAGGAATGAACACCAT
ACTGAGCCCGCAAATACCTTATTATATCAACAGAAAACAGTCGAAACTTCCCACGGAACCGATGTCGCAGGGACATGGAA
CGGAAACTGTGGAGGCCGTTTATAACTATCAGCCGCTTAAAGACGTGGATGCTGCCTTGCAACCTTATTATAAAGGTGTA
CAAGCCAACTTTTGGACCGAATGGGTGACCGAACCTTCCGTTCTCGAATACCTGATGTTGCCACGTCTTGCCGCCGTTGC
CGAAGCCGGATGGACACCACAAGAAAAAAGGAATTATGAAGACTTTAAAGAAAGGATTCGTAAGGATGCAGAGCTATACG
ACCTCAAAGGATGGAATTATGGCAAACATATCATGAAATAA

Upstream 100 bases:

>100_bases
AAAAAGAGCAAACAAAATAATCATAAAGACATACTTTTCTGATTTATTATTTCTATCTTCGTCCGCTGTTATACTTTTTA
TTTAAATACCCCCAATTACC

Downstream 100 bases:

>100_bases
GCAAACGCTTTCATTTGACTGCCGATAACTGGGGAGTGACTAAAAAGTCGGTAGTATCTCAATTCTCCTCCTTCGGGAAG
CTACCCTTTATACACAAGTA

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKIKHFLPLLLLLGSNEMLTAQEIALTPQPAHLTVKDGRFEFGNQLKAKVTPYQGDSIRMVFESFKKELQEATGIKVSST
QKEAKARIILDLNPQLPAEAYKLNVSKKQVRIEASRPAGFYYALQTLKQLMPRNVMAGVATSDHSQWSLPSVEIEDAPRF
EWRGFMLDEGRHFFGKDEIKRVIDMMAIYKMNRFHWHLTEDQGWRIEIKKYPKLTETGAWRNSKVLAYGDVKPDGERYGG
FYTQKDIKEIVAYAKKKFIEIIPEIDIPGHSQAAVAAYPEFLACDPRDKHEVWLQQGISTDVINVANPKAMQFAKEVIDE
LTELFPFNYIHLGGDECPTRKWQKNDECKKLLSEIGSSNFRDLQIYFYKQLKDYIATKPADQQRQLIFWNEVLHGNTSIL
GNDITIMAWIGANAAAKQAAKQGMNTILSPQIPYYINRKQSKLPTEPMSQGHGTETVEAVYNYQPLKDVDAALQPYYKGV
QANFWTEWVTEPSVLEYLMLPRLAAVAEAGWTPQEKRNYEDFKERIRKDAELYDLKGWNYGKHIMK

Sequences:

>Translated_546_residues
MKIKHFLPLLLLLGSNEMLTAQEIALTPQPAHLTVKDGRFEFGNQLKAKVTPYQGDSIRMVFESFKKELQEATGIKVSST
QKEAKARIILDLNPQLPAEAYKLNVSKKQVRIEASRPAGFYYALQTLKQLMPRNVMAGVATSDHSQWSLPSVEIEDAPRF
EWRGFMLDEGRHFFGKDEIKRVIDMMAIYKMNRFHWHLTEDQGWRIEIKKYPKLTETGAWRNSKVLAYGDVKPDGERYGG
FYTQKDIKEIVAYAKKKFIEIIPEIDIPGHSQAAVAAYPEFLACDPRDKHEVWLQQGISTDVINVANPKAMQFAKEVIDE
LTELFPFNYIHLGGDECPTRKWQKNDECKKLLSEIGSSNFRDLQIYFYKQLKDYIATKPADQQRQLIFWNEVLHGNTSIL
GNDITIMAWIGANAAAKQAAKQGMNTILSPQIPYYINRKQSKLPTEPMSQGHGTETVEAVYNYQPLKDVDAALQPYYKGV
QANFWTEWVTEPSVLEYLMLPRLAAVAEAGWTPQEKRNYEDFKERIRKDAELYDLKGWNYGKHIMK
>Mature_546_residues
MKIKHFLPLLLLLGSNEMLTAQEIALTPQPAHLTVKDGRFEFGNQLKAKVTPYQGDSIRMVFESFKKELQEATGIKVSST
QKEAKARIILDLNPQLPAEAYKLNVSKKQVRIEASRPAGFYYALQTLKQLMPRNVMAGVATSDHSQWSLPSVEIEDAPRF
EWRGFMLDEGRHFFGKDEIKRVIDMMAIYKMNRFHWHLTEDQGWRIEIKKYPKLTETGAWRNSKVLAYGDVKPDGERYGG
FYTQKDIKEIVAYAKKKFIEIIPEIDIPGHSQAAVAAYPEFLACDPRDKHEVWLQQGISTDVINVANPKAMQFAKEVIDE
LTELFPFNYIHLGGDECPTRKWQKNDECKKLLSEIGSSNFRDLQIYFYKQLKDYIATKPADQQRQLIFWNEVLHGNTSIL
GNDITIMAWIGANAAAKQAAKQGMNTILSPQIPYYINRKQSKLPTEPMSQGHGTETVEAVYNYQPLKDVDAALQPYYKGV
QANFWTEWVTEPSVLEYLMLPRLAAVAEAGWTPQEKRNYEDFKERIRKDAELYDLKGWNYGKHIMK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=442, Percent_Identity=25.3393665158371, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI189181666, Length=430, Percent_Identity=26.2790697674419, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17569815, Length=436, Percent_Identity=28.4403669724771, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45551090, Length=460, Percent_Identity=26.0869565217391, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24653074, Length=460, Percent_Identity=26.0869565217391, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281365639, Length=456, Percent_Identity=22.8070175438596, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24657474, Length=456, Percent_Identity=22.8070175438596, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24657468, Length=456, Percent_Identity=22.8070175438596, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17647501, Length=456, Percent_Identity=22.8070175438596, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17933586, Length=517, Percent_Identity=22.4371373307544, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 62834; Mature: 62834

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKHFLPLLLLLGSNEMLTAQEIALTPQPAHLTVKDGRFEFGNQLKAKVTPYQGDSIRM
CCHHHHHHHHHHHCCCCCEEHHHEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHH
VFESFKKELQEATGIKVSSTQKEAKARIILDLNPQLPAEAYKLNVSKKQVRIEASRPAGF
HHHHHHHHHHHHCCCEEECCHHCCCEEEEEECCCCCCCHHEEECCCCEEEEEEECCCCHH
YYALQTLKQLMPRNVMAGVATSDHSQWSLPSVEIEDAPRFEWRGFMLDEGRHFFGKDEIK
HHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEECCCCCCEECCEEECCCCCCCCHHHHH
RVIDMMAIYKMNRFHWHLTEDQGWRIEIKKYPKLTETGAWRNSKVLAYGDVKPDGERYGG
HHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHCC
FYTQKDIKEIVAYAKKKFIEIIPEIDIPGHSQAAVAAYPEFLACDPRDKHEVWLQQGIST
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHCCCCCCHHHHHHHCCCCC
DVINVANPKAMQFAKEVIDELTELFPFNYIHLGGDECPTRKWQKNDECKKLLSEIGSSNF
CEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCC
RDLQIYFYKQLKDYIATKPADQQRQLIFWNEVLHGNTSILGNDITIMAWIGANAAAKQAA
CEEHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHCCCCEEECCCEEEEEEECCCHHHHHHH
KQGMNTILSPQIPYYINRKQSKLPTEPMSQGHGTETVEAVYNYQPLKDVDAALQPYYKGV
HHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCC
QANFWTEWVTEPSVLEYLMLPRLAAVAEAGWTPQEKRNYEDFKERIRKDAELYDLKGWNY
CCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCEEECCCCCC
GKHIMK
CHHHCC
>Mature Secondary Structure
MKIKHFLPLLLLLGSNEMLTAQEIALTPQPAHLTVKDGRFEFGNQLKAKVTPYQGDSIRM
CCHHHHHHHHHHHCCCCCEEHHHEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHH
VFESFKKELQEATGIKVSSTQKEAKARIILDLNPQLPAEAYKLNVSKKQVRIEASRPAGF
HHHHHHHHHHHHCCCEEECCHHCCCEEEEEECCCCCCCHHEEECCCCEEEEEEECCCCHH
YYALQTLKQLMPRNVMAGVATSDHSQWSLPSVEIEDAPRFEWRGFMLDEGRHFFGKDEIK
HHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEECCCCCCEECCEEECCCCCCCCHHHHH
RVIDMMAIYKMNRFHWHLTEDQGWRIEIKKYPKLTETGAWRNSKVLAYGDVKPDGERYGG
HHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHCC
FYTQKDIKEIVAYAKKKFIEIIPEIDIPGHSQAAVAAYPEFLACDPRDKHEVWLQQGIST
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHCCCCCCHHHHHHHCCCCC
DVINVANPKAMQFAKEVIDELTELFPFNYIHLGGDECPTRKWQKNDECKKLLSEIGSSNF
CEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCC
RDLQIYFYKQLKDYIATKPADQQRQLIFWNEVLHGNTSILGNDITIMAWIGANAAAKQAA
CEEHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHCCCCEEECCCEEEEEEECCCHHHHHHH
KQGMNTILSPQIPYYINRKQSKLPTEPMSQGHGTETVEAVYNYQPLKDVDAALQPYYKGV
HHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCC
QANFWTEWVTEPSVLEYLMLPRLAAVAEAGWTPQEKRNYEDFKERIRKDAELYDLKGWNY
CCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCEEECCCCCC
GKHIMK
CHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]