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The map label for this gene is zraR [H]

Identifier: 29349209

GI number: 29349209

Start: 4942909

End: 4944282

Strand: Reverse

Name: zraR [H]

Synonym: BT_3801

Alternate gene names: 29349209

Gene position: 4944282-4942909 (Counterclockwise)

Preceding gene: 29349226

Following gene: 29349207

Centisome position: 78.98

GC content: 46.51

Gene sequence:

>1374_bases
ATGATGAAATCCATATTGATAATAGAAGACGATATCACTTTCGGAATGATGCTGAAAACCTGGCTAAGTAAAAAAGGGTT
TGAGGTGTCATCAGTCAGTAACATTGCCCGTGCCCAGAAGCACATTGAAGGACAAGGGGCAGACTTAATCCTGTCCGATT
TACGCTTACCGGATCACGACGGAATCGATCTTCTGAAATGGATGAACGAAAAAGGAATCGATATTCCTTTGATCATCATG
ACCGGTTATGCCGATATCCAATCGGCAGTACAAGCGATGAAACTGGGAGCACGCGATTATGTTGCCAAACCGGTGAATCC
GGAGGAACTACTCAAAAAGATGTCAGAAGCTTTGCAAGCGAAAGAAGCGCCGACTACGCATACCGCAGCCAAAACTTCTG
CAAAGAAAGGTTCTTCCATTTCGTCCGGAAACGCCACCGAAACCCATCATGCTTATCTGGAAGGAGAAAGTGATGCCGCC
AAGCAACTCTATAATTATGTAGGTCTGGTAGCTCCCACCAATATGTCCGTACTGATCAACGGTTCCAGCGGAACGGGGAA
AGAGTATGTGGCGCACCGCATCCATCAACTGAGCAAACGGAATGACAAGCCGTTTATCGCGGTAGACTGCGGTTCGATTC
CCAAAGAATTAGCTGCATCCGAGTTTTTCGGCCATGTGAAGGGCTCTTTTACAGGAGCACTGACGGACAAGACCGGAGCG
TTCGTTGCCGCCAATGGAGGCACTATCTTCCTGGATGAAATAGGAAATCTCAGTTACGAGGTACAGATACAACTTCTCCG
TGCCTTGCAAGAGAGAAAGATTCGTCCGGTCGGTTCCACGCAAGAGGTATCGGTTGATATCCGTCTGGTATCCGCCACCA
ACGAGAATCTGGAACAGGCTATCGAGAAAGGTACTTTCCGTGAAGACCTTTTCCATCGCATCAATGAATTTACCCTGCGG
ATGCCCGACCTGAAAGAACGGAAAGAGGATATCCTGTTGTTTGCCAACTTCTTCCTCGATCAGGCAAACAAGGAACTGGA
CAAGCATCTGATCGGTTTTGACTCGAAAGCCTCACAAGCCTTACTCAATTATCACTGGCCGGGCAACTTACGCCAAATGA
AGAATATCGTAAAAAGAGCGACTTTACTGGCACAAGGAAGTTTCATCACTCTTCTTGAATTAGGGACCGAATTACTGGAA
ACAAGTACCGTTTGTTCCGCAAGCATGGCGCTACGCAACGAAGAAACAGAGAAAGAACACATTCTGGAGGCATTGCGCCA
AACCGGAAATAACAAGAGCAAAGCGGCACAATTACTGAATATCGACCGGAAGACATTATATAATAAGCTGAAACTATATA
ATATCGACTTGTAG

Upstream 100 bases:

>100_bases
AATCTTTTTCATAACACTTTTATTTAATTTAAGTTTGCAAATATACTACTTTCGCCCAAATCCTCTTACCTTTGTAGCAT
TAAAAGAGGCAAAAGAGAGT

Downstream 100 bases:

>100_bases
GTTATCGATCAGTACTACCCATATATTTAGAAGGAGATACGCCGAACTGCTCCATGAAGTGCTTGCGCAAAGTACGGGTA
TCGGAATAACCAACCATTTC

Product: rteB, two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MMKSILIIEDDITFGMMLKTWLSKKGFEVSSVSNIARAQKHIEGQGADLILSDLRLPDHDGIDLLKWMNEKGIDIPLIIM
TGYADIQSAVQAMKLGARDYVAKPVNPEELLKKMSEALQAKEAPTTHTAAKTSAKKGSSISSGNATETHHAYLEGESDAA
KQLYNYVGLVAPTNMSVLINGSSGTGKEYVAHRIHQLSKRNDKPFIAVDCGSIPKELAASEFFGHVKGSFTGALTDKTGA
FVAANGGTIFLDEIGNLSYEVQIQLLRALQERKIRPVGSTQEVSVDIRLVSATNENLEQAIEKGTFREDLFHRINEFTLR
MPDLKERKEDILLFANFFLDQANKELDKHLIGFDSKASQALLNYHWPGNLRQMKNIVKRATLLAQGSFITLLELGTELLE
TSTVCSASMALRNEETEKEHILEALRQTGNNKSKAAQLLNIDRKTLYNKLKLYNIDL

Sequences:

>Translated_457_residues
MMKSILIIEDDITFGMMLKTWLSKKGFEVSSVSNIARAQKHIEGQGADLILSDLRLPDHDGIDLLKWMNEKGIDIPLIIM
TGYADIQSAVQAMKLGARDYVAKPVNPEELLKKMSEALQAKEAPTTHTAAKTSAKKGSSISSGNATETHHAYLEGESDAA
KQLYNYVGLVAPTNMSVLINGSSGTGKEYVAHRIHQLSKRNDKPFIAVDCGSIPKELAASEFFGHVKGSFTGALTDKTGA
FVAANGGTIFLDEIGNLSYEVQIQLLRALQERKIRPVGSTQEVSVDIRLVSATNENLEQAIEKGTFREDLFHRINEFTLR
MPDLKERKEDILLFANFFLDQANKELDKHLIGFDSKASQALLNYHWPGNLRQMKNIVKRATLLAQGSFITLLELGTELLE
TSTVCSASMALRNEETEKEHILEALRQTGNNKSKAAQLLNIDRKTLYNKLKLYNIDL
>Mature_457_residues
MMKSILIIEDDITFGMMLKTWLSKKGFEVSSVSNIARAQKHIEGQGADLILSDLRLPDHDGIDLLKWMNEKGIDIPLIIM
TGYADIQSAVQAMKLGARDYVAKPVNPEELLKKMSEALQAKEAPTTHTAAKTSAKKGSSISSGNATETHHAYLEGESDAA
KQLYNYVGLVAPTNMSVLINGSSGTGKEYVAHRIHQLSKRNDKPFIAVDCGSIPKELAASEFFGHVKGSFTGALTDKTGA
FVAANGGTIFLDEIGNLSYEVQIQLLRALQERKIRPVGSTQEVSVDIRLVSATNENLEQAIEKGTFREDLFHRINEFTLR
MPDLKERKEDILLFANFFLDQANKELDKHLIGFDSKASQALLNYHWPGNLRQMKNIVKRATLLAQGSFITLLELGTELLE
TSTVCSASMALRNEETEKEHILEALRQTGNNKSKAAQLLNIDRKTLYNKLKLYNIDL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=447, Percent_Identity=39.8210290827741, Blast_Score=334, Evalue=9e-93,
Organism=Escherichia coli, GI1788550, Length=470, Percent_Identity=38.2978723404255, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1790299, Length=473, Percent_Identity=36.3636363636364, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1788905, Length=452, Percent_Identity=34.9557522123894, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1789233, Length=335, Percent_Identity=42.3880597014925, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082117, Length=317, Percent_Identity=39.1167192429022, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789087, Length=316, Percent_Identity=35.126582278481, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI87082152, Length=310, Percent_Identity=36.4516129032258, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=36.4779874213836, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1786524, Length=339, Percent_Identity=34.5132743362832, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787583, Length=284, Percent_Identity=34.5070422535211, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789828, Length=291, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87081858, Length=311, Percent_Identity=26.6881028938907, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=31.1475409836066, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789402, Length=100, Percent_Identity=38, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787229, Length=118, Percent_Identity=30.5084745762712, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787375, Length=110, Percent_Identity=28.1818181818182, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=28.099173553719, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790552, Length=115, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786911, Length=124, Percent_Identity=29.8387096774194, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50680; Mature: 50680

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKSILIIEDDITFGMMLKTWLSKKGFEVSSVSNIARAQKHIEGQGADLILSDLRLPDHD
CCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
GIDLLKWMNEKGIDIPLIIMTGYADIQSAVQAMKLGARDYVAKPVNPEELLKKMSEALQA
CHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
KEAPTTHTAAKTSAKKGSSISSGNATETHHAYLEGESDAAKQLYNYVGLVAPTNMSVLIN
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCEEECCCEEEEEE
GSSGTGKEYVAHRIHQLSKRNDKPFIAVDCGSIPKELAASEFFGHVKGSFTGALTDKTGA
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCE
FVAANGGTIFLDEIGNLSYEVQIQLLRALQERKIRPVGSTQEVSVDIRLVSATNENLEQA
EEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHH
IEKGTFREDLFHRINEFTLRMPDLKERKEDILLFANFFLDQANKELDKHLIGFDSKASQA
HHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LLNYHWPGNLRQMKNIVKRATLLAQGSFITLLELGTELLETSTVCSASMALRNEETEKEH
HEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ILEALRQTGNNKSKAAQLLNIDRKTLYNKLKLYNIDL
HHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHEEEECC
>Mature Secondary Structure
MMKSILIIEDDITFGMMLKTWLSKKGFEVSSVSNIARAQKHIEGQGADLILSDLRLPDHD
CCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
GIDLLKWMNEKGIDIPLIIMTGYADIQSAVQAMKLGARDYVAKPVNPEELLKKMSEALQA
CHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
KEAPTTHTAAKTSAKKGSSISSGNATETHHAYLEGESDAAKQLYNYVGLVAPTNMSVLIN
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCEEECCCEEEEEE
GSSGTGKEYVAHRIHQLSKRNDKPFIAVDCGSIPKELAASEFFGHVKGSFTGALTDKTGA
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCE
FVAANGGTIFLDEIGNLSYEVQIQLLRALQERKIRPVGSTQEVSVDIRLVSATNENLEQA
EEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHH
IEKGTFREDLFHRINEFTLRMPDLKERKEDILLFANFFLDQANKELDKHLIGFDSKASQA
HHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LLNYHWPGNLRQMKNIVKRATLLAQGSFITLLELGTELLETSTVCSASMALRNEETEKEH
HEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ILEALRQTGNNKSKAAQLLNIDRKTLYNKLKLYNIDL
HHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]