Click here to switch to the map view.

The map label for this gene is sglT [H]

Identifier: 29349031

GI number: 29349031

Start: 4694785

End: 4696272

Strand: Reverse

Name: sglT [H]

Synonym: BT_3623

Alternate gene names: 29349031

Gene position: 4696272-4694785 (Counterclockwise)

Preceding gene: 29349032

Following gene: 29349030

Centisome position: 75.02

GC content: 43.28

Gene sequence:

>1488_bases
ATGAGTCCAATTATCTTATCTATTACTATCATAGCATACTTTATGATCCTTTTCGCTATCTCCTATATAGCAGGACATAA
AGCGGATAACGAAGGCTTCTTCGTCGGCAACCGCAAATCGGCATGGTATATTGTCGCCTTTGCCATGATTGGTTCCACTA
TCTCCGGAGTTACGTTTGTATCCGTACCGGGTATGGTACAAGCCAGCGGCTTCTCCTACCTGCAAATGGTACTGGGATTT
ATCGTCGGACAGTTCATTATCGCATTCATACTCGTTCCGCTTTTCTACCGGATGAATCTGGTTTCTATCTATGAATATCT
TGAAAATCGCTTCGGAGCTTCTTCCTATAAGACAGGAGCCTGGTTTTTCTTTATTTCCAAAATGCTCGGAGCTGCCGTGC
GGCTCTTTTTAGTATGTCTGACCTTGCAATTACTCATCTTCGAGCCTTTCCATATTCCCTTTATAATCAATGTCATACTG
ACAGTACTCATTGTCTGGCTCTATACTTTCCGGGGAGGAGTGAAATCATTGATATGGACTGATGTACTGAAAACATTCTG
TCTGGTAGTCTCCGTCGTACTTTGTATCTACTATATAGCTTCCAGCCTGCATCTGAATTTCAGCGGATTGGTCTCAACGA
TTTCAGACAACGATCTCTCCAAAATGTTCTTTTTTGACGATGTCAACGACAAGCGATATTTCTTCAAGCAATTCCTGGCA
GGAGTCTTTACCGTTATCGCCATGAACGGGCTGGATCAGGATATGATGCAACGGAATCTCAGTTGCAAGAACTTCCGTGA
CTCACAGAAGAATATGATTACAAGCGGGATTTCACAGTTCTTTGTGATCCTGCTCTTCCTGATGCTGGGTGTCTTGCTCT
ATACTTTCACCGCCCGACAGGGAATCGAGAATCCCGGTAAGAGCGATGAATTGTTCCCAATGATCGCCACAGGCAATTAC
TTTCCGGGAATAGTCGGTATCCTGTTCATTATCGGATTGATAGCTTCGGCGTACTCCGCTGCCGGATCGGCCTTGACAGC
CCTGACGACTTCTTTCACCGTAGATATTCTGAATGCGCACAAGAAAGACGAAGCGGCACTCAGCAAAATACGGAAACACG
TGCACATCGGGATGGCATTCGTGATGGGAATCGTCATCTTCGTATTCAATTTACTGAATAATACGAGTGTGATTGATGCG
ATTTATACGCTGGCCAGTTATACGTATGGTCCAATTCTCGGACTATTCGCTTTCGGCATTTTTACTAAAAAACAAGTTTA
TGATCCATATATTCCGTTAGTAGCCATTCTTTCTCCTGCACTTTGCTACGTATTGCAAAGAAATTCGGAAGCCTGGTTCG
ATGGATATCAAATTAGCTACGAGTTACTGATATTGAATGCTGCGTTTACTTTTCTGGGGCTTTGCCTGCTCATCAAAAGG
AAATCGTCAGTAGCCCCTATCAACAACTCTTTAATAAAAAAACATTAA

Upstream 100 bases:

>100_bases
AGAAGGATGCATTTATTTGATAAATTCCCTACATTTGTACAATTTGTAGGAAAAGCATATTTGAATATATTCACCCGCGA
ACGAATTTTAAGCAACAGAT

Downstream 100 bases:

>100_bases
AATGAAAAAGAAAATCAATTGCTTCATACCTTTTGGCAATCCGAAAGATACGATACAAACTGTAAAAGAATTGCAAGCTT
CAGAATTAGTGAACAAAATC

Product: sodium/iodide co-transporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSPIILSITIIAYFMILFAISYIAGHKADNEGFFVGNRKSAWYIVAFAMIGSTISGVTFVSVPGMVQASGFSYLQMVLGF
IVGQFIIAFILVPLFYRMNLVSIYEYLENRFGASSYKTGAWFFFISKMLGAAVRLFLVCLTLQLLIFEPFHIPFIINVIL
TVLIVWLYTFRGGVKSLIWTDVLKTFCLVVSVVLCIYYIASSLHLNFSGLVSTISDNDLSKMFFFDDVNDKRYFFKQFLA
GVFTVIAMNGLDQDMMQRNLSCKNFRDSQKNMITSGISQFFVILLFLMLGVLLYTFTARQGIENPGKSDELFPMIATGNY
FPGIVGILFIIGLIASAYSAAGSALTALTTSFTVDILNAHKKDEAALSKIRKHVHIGMAFVMGIVIFVFNLLNNTSVIDA
IYTLASYTYGPILGLFAFGIFTKKQVYDPYIPLVAILSPALCYVLQRNSEAWFDGYQISYELLILNAAFTFLGLCLLIKR
KSSVAPINNSLIKKH

Sequences:

>Translated_495_residues
MSPIILSITIIAYFMILFAISYIAGHKADNEGFFVGNRKSAWYIVAFAMIGSTISGVTFVSVPGMVQASGFSYLQMVLGF
IVGQFIIAFILVPLFYRMNLVSIYEYLENRFGASSYKTGAWFFFISKMLGAAVRLFLVCLTLQLLIFEPFHIPFIINVIL
TVLIVWLYTFRGGVKSLIWTDVLKTFCLVVSVVLCIYYIASSLHLNFSGLVSTISDNDLSKMFFFDDVNDKRYFFKQFLA
GVFTVIAMNGLDQDMMQRNLSCKNFRDSQKNMITSGISQFFVILLFLMLGVLLYTFTARQGIENPGKSDELFPMIATGNY
FPGIVGILFIIGLIASAYSAAGSALTALTTSFTVDILNAHKKDEAALSKIRKHVHIGMAFVMGIVIFVFNLLNNTSVIDA
IYTLASYTYGPILGLFAFGIFTKKQVYDPYIPLVAILSPALCYVLQRNSEAWFDGYQISYELLILNAAFTFLGLCLLIKR
KSSVAPINNSLIKKH
>Mature_494_residues
SPIILSITIIAYFMILFAISYIAGHKADNEGFFVGNRKSAWYIVAFAMIGSTISGVTFVSVPGMVQASGFSYLQMVLGFI
VGQFIIAFILVPLFYRMNLVSIYEYLENRFGASSYKTGAWFFFISKMLGAAVRLFLVCLTLQLLIFEPFHIPFIINVILT
VLIVWLYTFRGGVKSLIWTDVLKTFCLVVSVVLCIYYIASSLHLNFSGLVSTISDNDLSKMFFFDDVNDKRYFFKQFLAG
VFTVIAMNGLDQDMMQRNLSCKNFRDSQKNMITSGISQFFVILLFLMLGVLLYTFTARQGIENPGKSDELFPMIATGNYF
PGIVGILFIIGLIASAYSAAGSALTALTTSFTVDILNAHKKDEAALSKIRKHVHIGMAFVMGIVIFVFNLLNNTSVIDAI
YTLASYTYGPILGLFAFGIFTKKQVYDPYIPLVAILSPALCYVLQRNSEAWFDGYQISYELLILNAAFTFLGLCLLIKRK
SSVAPINNSLIKKH

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=412, Percent_Identity=23.7864077669903, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI157671931, Length=410, Percent_Identity=23.4146341463415, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI167466278, Length=421, Percent_Identity=24.7030878859857, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI256985183, Length=404, Percent_Identity=25.4950495049505, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI110835708, Length=467, Percent_Identity=21.1991434689507, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI14140236, Length=454, Percent_Identity=20.9251101321586, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI17941285, Length=452, Percent_Identity=19.9115044247788, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4507031, Length=461, Percent_Identity=21.2581344902386, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32566512, Length=355, Percent_Identity=22.5352112676056, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640370, Length=400, Percent_Identity=25.25, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24651739, Length=456, Percent_Identity=23.6842105263158, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI221459584, Length=455, Percent_Identity=25.0549450549451, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24645928, Length=401, Percent_Identity=24.1895261845387, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281362918, Length=411, Percent_Identity=24.0875912408759, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573698, Length=423, Percent_Identity=22.9314420803783, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650192, Length=407, Percent_Identity=24.0786240786241, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24651741, Length=413, Percent_Identity=21.7917675544794, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221459588, Length=413, Percent_Identity=23.728813559322, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221459586, Length=406, Percent_Identity=23.1527093596059, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641117, Length=271, Percent_Identity=22.5092250922509, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28574994, Length=433, Percent_Identity=24.4803695150115, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221459582, Length=401, Percent_Identity=24.4389027431421, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362054, Length=375, Percent_Identity=23.2, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362052, Length=375, Percent_Identity=23.2, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362050, Length=375, Percent_Identity=23.2, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648056, Length=375, Percent_Identity=23.2, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356827, Length=375, Percent_Identity=23.2, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920916, Length=403, Percent_Identity=22.5806451612903, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281364280, Length=413, Percent_Identity=23.2445520581114, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221379702, Length=380, Percent_Identity=22.6315789473684, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 55323; Mature: 55192

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCHHHCCC
>Mature Secondary Structure 
SPIILSITIIAYFMILFAISYIAGHKADNEGFFVGNRKSAWYIVAFAMIGSTISGVTFV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCHHCCCEEE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CCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]