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The map label for this gene is glmS [H]

Identifier: 29349009

GI number: 29349009

Start: 4664397

End: 4665446

Strand: Reverse

Name: glmS [H]

Synonym: BT_3601

Alternate gene names: 29349009

Gene position: 4665446-4664397 (Counterclockwise)

Preceding gene: 29349010

Following gene: 29349008

Centisome position: 74.52

GC content: 36.67

Gene sequence:

>1050_bases
ATGGTACAATTTTTCCAAGAAATACAAGAGCAACCGCAAGCACTTCTGCAGACGGCAAACTTCTACAAAAGCGTAGAAGG
AAAATCCGTTTTGTCACAAATTTCAGAATTATGGTGTTCCGGCAAATATAGAAATATTCTGTTAACCGGTATGGGCAGTT
CTTACTTCATCGCTAACGCAACTGCTTCTCTACTTAATTCATATAAAATCCCGGCATATGCTCTGAACGCAGGAGAATTA
TTGCATTATCAAATTTCATTAATTAGTCCAGAATCGTTGATTATATGTATTTCGCAATCAGGAGAAAGCTATGAAGTAAT
CAAACTAATAGAAAAGTTATCTTCAAACATCACAGTTCTTTCTATTTGTAATGAAAAAGATAGCAGTTTAGTCAAATTCT
CTCGCTATAGCCTATTGTGCAAAGCTGGAAAGGAAGAAAAAACGTCAACAAAAACATTCATAACCTGTTATCAAGTAGCA
TATTTACTGGCAATGAAGTTATGCAATCAAGAAATCGACAGCACCCAATGGCATAAACTCAGTAAAATTATTGAGAACAT
GGTCAATGGAAATACTCCATGGATGTCGAAAGCTATTGAACTGATAGACGGCTCCACTTTTGTGCAATTAATAGGACGGG
GACCAGTTTTTGCAGCTGCCAGCCAGAGTGCATTGATGTTCATGGAAGCAGCGCATACGCCTGCATCAGCTTTATTAGGT
GGTGAATTCAGGCATGGCCCGTTAGAAATGGTAAAGAAAGGATTCATAGCCATTCTATTTGCACACTCGCAATCAGAAAC
CTACGAACAATCACTATCTTTAGTAAAAGATATCCTTAAATATGAAGGAAAAGTTATCTTTATCACCGATTCAAACTTAG
TGTTTGAAAATGATAATTTATGTGCCATTACTATCCCAAGCACTAATGCTGAGTTATTTACAATCCCCTGTATAGTTCCT
GTACAACTTCTTATAAATACATGGGCAACCAAATGCGGAATAATACCAGGAGAATTTACACATGGTGCCAAAATAACATC
AATCGAATAA

Upstream 100 bases:

>100_bases
CTATAAACTACTCAGTAACAGTTGGCAATTACATATGAATAATTGCACAACTGTTGCTAAGTAGTTATTAAAGTCACTAG
ATTATAATTAAAAAAATCCG

Downstream 100 bases:

>100_bases
ACTATGAGAATTGTGTATCCAAAGAAAATTGCAATTGGAGTCGATATTGGCGGGACTAAAATAAAAGCCGGACTTGTCGA
TATTAACGGACAGATAATCG

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MVQFFQEIQEQPQALLQTANFYKSVEGKSVLSQISELWCSGKYRNILLTGMGSSYFIANATASLLNSYKIPAYALNAGEL
LHYQISLISPESLIICISQSGESYEVIKLIEKLSSNITVLSICNEKDSSLVKFSRYSLLCKAGKEEKTSTKTFITCYQVA
YLLAMKLCNQEIDSTQWHKLSKIIENMVNGNTPWMSKAIELIDGSTFVQLIGRGPVFAAASQSALMFMEAAHTPASALLG
GEFRHGPLEMVKKGFIAILFAHSQSETYEQSLSLVKDILKYEGKVIFITDSNLVFENDNLCAITIPSTNAELFTIPCIVP
VQLLINTWATKCGIIPGEFTHGAKITSIE

Sequences:

>Translated_349_residues
MVQFFQEIQEQPQALLQTANFYKSVEGKSVLSQISELWCSGKYRNILLTGMGSSYFIANATASLLNSYKIPAYALNAGEL
LHYQISLISPESLIICISQSGESYEVIKLIEKLSSNITVLSICNEKDSSLVKFSRYSLLCKAGKEEKTSTKTFITCYQVA
YLLAMKLCNQEIDSTQWHKLSKIIENMVNGNTPWMSKAIELIDGSTFVQLIGRGPVFAAASQSALMFMEAAHTPASALLG
GEFRHGPLEMVKKGFIAILFAHSQSETYEQSLSLVKDILKYEGKVIFITDSNLVFENDNLCAITIPSTNAELFTIPCIVP
VQLLINTWATKCGIIPGEFTHGAKITSIE
>Mature_349_residues
MVQFFQEIQEQPQALLQTANFYKSVEGKSVLSQISELWCSGKYRNILLTGMGSSYFIANATASLLNSYKIPAYALNAGEL
LHYQISLISPESLIICISQSGESYEVIKLIEKLSSNITVLSICNEKDSSLVKFSRYSLLCKAGKEEKTSTKTFITCYQVA
YLLAMKLCNQEIDSTQWHKLSKIIENMVNGNTPWMSKAIELIDGSTFVQLIGRGPVFAAASQSALMFMEAAHTPASALLG
GEFRHGPLEMVKKGFIAILFAHSQSETYEQSLSLVKDILKYEGKVIFITDSNLVFENDNLCAITIPSTNAELFTIPCIVP
VQLLINTWATKCGIIPGEFTHGAKITSIE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=337, Percent_Identity=23.7388724035608, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790167, Length=342, Percent_Identity=28.6549707602339, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789588, Length=109, Percent_Identity=31.1926605504587, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539970, Length=338, Percent_Identity=25.1479289940828, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17532897, Length=336, Percent_Identity=24.4047619047619, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532899, Length=336, Percent_Identity=24.4047619047619, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322745, Length=358, Percent_Identity=24.3016759776536, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357745, Length=338, Percent_Identity=23.3727810650888, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 38564; Mature: 38564

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQFFQEIQEQPQALLQTANFYKSVEGKSVLSQISELWCSGKYRNILLTGMGSSYFIANA
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHH
TASLLNSYKIPAYALNAGELLHYQISLISPESLIICISQSGESYEVIKLIEKLSSNITVL
HHHHHHCCCCCEEEECCCCEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHCCCEEEE
SICNEKDSSLVKFSRYSLLCKAGKEEKTSTKTFITCYQVAYLLAMKLCNQEIDSTQWHKL
EEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SKIIENMVNGNTPWMSKAIELIDGSTFVQLIGRGPVFAAASQSALMFMEAAHTPASALLG
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCEEECCCCHHHHHHHHCCCCHHHHHC
GEFRHGPLEMVKKGFIAILFAHSQSETYEQSLSLVKDILKYEGKVIFITDSNLVFENDNL
CCCCCCHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCE
CAITIPSTNAELFTIPCIVPVQLLINTWATKCGIIPGEFTHGAKITSIE
EEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MVQFFQEIQEQPQALLQTANFYKSVEGKSVLSQISELWCSGKYRNILLTGMGSSYFIANA
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHH
TASLLNSYKIPAYALNAGELLHYQISLISPESLIICISQSGESYEVIKLIEKLSSNITVL
HHHHHHCCCCCEEEECCCCEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHCCCEEEE
SICNEKDSSLVKFSRYSLLCKAGKEEKTSTKTFITCYQVAYLLAMKLCNQEIDSTQWHKL
EEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SKIIENMVNGNTPWMSKAIELIDGSTFVQLIGRGPVFAAASQSALMFMEAAHTPASALLG
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCEEECCCCHHHHHHHHCCCCHHHHHC
GEFRHGPLEMVKKGFIAILFAHSQSETYEQSLSLVKDILKYEGKVIFITDSNLVFENDNL
CCCCCCHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCE
CAITIPSTNAELFTIPCIVPVQLLINTWATKCGIIPGEFTHGAKITSIE
EEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]