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The map label for this gene is spoVD [H]

Identifier: 29348862

GI number: 29348862

Start: 4448603

End: 4450729

Strand: Reverse

Name: spoVD [H]

Synonym: BT_3453

Alternate gene names: 29348862

Gene position: 4450729-4448603 (Counterclockwise)

Preceding gene: 29348863

Following gene: 29348861

Centisome position: 71.09

GC content: 48.0

Gene sequence:

>2127_bases
ATGACCCGTTACTTCTTTGTCATTCTGATCATGGCACTGATAGGAGTAGCAATTGTCGTCAAGGCAGGCGTGACCATGTT
TGCCGAACGACAGTACTGGCAGGATGTAGCCGATCGTTTCGTAAAAGAAAACGTGACGGTGAAACCTAACCGCGGAAACA
TTATTTCTTCTGACGGTAAACTGATGGCAAGTTCACTGCCTGAATACAGAATCTACATGGACTTTATGTCCGGTGAAAAG
GACGAAAAAAGAAGAAAGAAGGATCAGGCACGTCGGGATTCCATCCTCAAAGCCAATATGGATTCGATTTGCATCGGACT
GCATAAGATATTCCCCGACAAAAGTGCGGCACAATTCAAGGCACACCTTCAAAAAGGACGTCAGGCCAAAAGCCGTAACT
ACCTGATCTACCCGAAGCGTATCTCTTATATACAATATAAAGAGGTGAAACGTCTGCCTGTCTTCTGTCTGAACCGCTAT
AAGGGAGGATTCAAGGAGTTGGCATATAATCAGCGCAAGAAACCTTTCGGCTCATTGGCAGCCCGTACCCTGGGAGATGT
ATATGCCGATACAGCCCAAGGAGCAAAGAACGGTATAGAACTCGCGTTCGATACGATTCTGAAAGGACGTGACGGGCTAA
CTCACCGCCAAAAGGTGATGAACAAATACCTGAACATTGTCGATGTCGCCCCGATCGACGGTTGCGACCTGATCACCACC
ATCGATGTAGGTATGCAGGATATTTGCGAAAAAGCATTGGTAGACAAGCTGAAAGAATTGAACGCCACCGTGGGTGTAGT
CGTATTGATGGAAGTTGCAACCGGAGAAGTAAAAGCCATCGTCAATATGACGCAAGGCAGAGACGGTGAATATTATGAAG
TACGCAACAATGCAATCAGCGATATGCTCGAACCGGGTTCTACCTTCAAGACAGCCTCTATCATGGTAGCTCTGGAAGAC
GGAAAAATCACTCCGGACTATATCGTAGACACCGGCAACGGACAAAAGCCGATGCATGGCCGTGTCATGAAAGACCACAA
CTGGCATCGAGGCGGATACGGCAAACTGACTGTTACCGAGATTTTGGGAGTATCGTCCAATGTCGGAACTTCTAGCATCA
TCGAGAACTTTTACGGAAGCAACCCGCAGAAGTTTGTGGACGGACTGAAACGGATGAGCATCGACCAGCCACTCCACCTG
CAAATATCCGGAGAAGGAAAGCCGAATATTCGTGGTCCGAAAGAACGCTATTTTTCAAAAACGACTTTGCCATGGATGAG
CATCGGCTATGAAACGCAGGTTCCACCGATCAATATTCTGACATTCTATAATGCAATAGCCAATAACGGAGTATCCATAC
GTCCGAAGTTTGTAAAAGCCGCCGTCAGAGACGGAGAAGTGATAAAGGAATATCCGACGGAAATCATCAATCCCAAGATC
TGTTCGGACAAGACGCTGGCACAAATACGGGAAATCCTGCGGAAAGTGGTAGGTGAAGGACTTGCCAAACCGGCAGGAAG
CAAGCAGTTCCATGTGTCCGGTAAGACCGGAACAGCACAGGTTTCGCAGGGAGCAGCCGGCTACAAGACAGGAAGAACCA
ATTATCTCGTCAGCTTCTGCGGATACTTCCCATCGGAAGAGCCGAAGTACAGTATGATTGTTTCGATCCAGAAACCCGGT
TTGCCCGCTTCGGGAGGTTTGATGGCAGGTAGCGTATTCAGCAAGATCGCAGAAAGAGTGTATGCCAAAGACCTGCGCTT
GCCACTCACAAGTGCCATTGATACGAATACGGTAGTCATCCCGAACGTTAAGGCAGGAGAAATGAGGGAAACGCAACGGG
TACTGGAAGAACTGAATATAAAGATACAGGGAAAAATCACCGATTCGGGAAAAGAAGTATGGGGAAGCACCCATCCCGCC
CCTCAGGCGGTAGTTCTTGAAAGCCGGGGTATCATGCAGAACTTCGTGCCAAGCGTCGTAGGCATGGGAGCGAAAGATGC
TGTTTATCTATTGGAAAGCAAAGGATTGAAAGTCAATCTGGTGGGAGTCGGGAAAGTAAAAAGCCAGTCGATAGCCAACG
GCAGTGTTGCAAGAAAAGGGCAGACGATTACGCTTACGTTGCATTAA

Upstream 100 bases:

>100_bases
TTTGCAGACCTCTACCAACCCGCCTTACCTTATTAAATAAGGTGTAAGTGGAGAGTCTTAAAAGAGAATAAGCACTGTGG
CAGTAAATAAGAAAAATATA

Downstream 100 bases:

>100_bases
GAATTAAATTAAGTAGGACAGATATGTTATTAAACGAGTTACTGAAAGCAATCCAGCCGGTGCAAGTGACCGGAGATTCA
AGGATAGAGATCACCGGAGT

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 708; Mature: 707

Protein sequence:

>708_residues
MTRYFFVILIMALIGVAIVVKAGVTMFAERQYWQDVADRFVKENVTVKPNRGNIISSDGKLMASSLPEYRIYMDFMSGEK
DEKRRKKDQARRDSILKANMDSICIGLHKIFPDKSAAQFKAHLQKGRQAKSRNYLIYPKRISYIQYKEVKRLPVFCLNRY
KGGFKELAYNQRKKPFGSLAARTLGDVYADTAQGAKNGIELAFDTILKGRDGLTHRQKVMNKYLNIVDVAPIDGCDLITT
IDVGMQDICEKALVDKLKELNATVGVVVLMEVATGEVKAIVNMTQGRDGEYYEVRNNAISDMLEPGSTFKTASIMVALED
GKITPDYIVDTGNGQKPMHGRVMKDHNWHRGGYGKLTVTEILGVSSNVGTSSIIENFYGSNPQKFVDGLKRMSIDQPLHL
QISGEGKPNIRGPKERYFSKTTLPWMSIGYETQVPPINILTFYNAIANNGVSIRPKFVKAAVRDGEVIKEYPTEIINPKI
CSDKTLAQIREILRKVVGEGLAKPAGSKQFHVSGKTGTAQVSQGAAGYKTGRTNYLVSFCGYFPSEEPKYSMIVSIQKPG
LPASGGLMAGSVFSKIAERVYAKDLRLPLTSAIDTNTVVIPNVKAGEMRETQRVLEELNIKIQGKITDSGKEVWGSTHPA
PQAVVLESRGIMQNFVPSVVGMGAKDAVYLLESKGLKVNLVGVGKVKSQSIANGSVARKGQTITLTLH

Sequences:

>Translated_708_residues
MTRYFFVILIMALIGVAIVVKAGVTMFAERQYWQDVADRFVKENVTVKPNRGNIISSDGKLMASSLPEYRIYMDFMSGEK
DEKRRKKDQARRDSILKANMDSICIGLHKIFPDKSAAQFKAHLQKGRQAKSRNYLIYPKRISYIQYKEVKRLPVFCLNRY
KGGFKELAYNQRKKPFGSLAARTLGDVYADTAQGAKNGIELAFDTILKGRDGLTHRQKVMNKYLNIVDVAPIDGCDLITT
IDVGMQDICEKALVDKLKELNATVGVVVLMEVATGEVKAIVNMTQGRDGEYYEVRNNAISDMLEPGSTFKTASIMVALED
GKITPDYIVDTGNGQKPMHGRVMKDHNWHRGGYGKLTVTEILGVSSNVGTSSIIENFYGSNPQKFVDGLKRMSIDQPLHL
QISGEGKPNIRGPKERYFSKTTLPWMSIGYETQVPPINILTFYNAIANNGVSIRPKFVKAAVRDGEVIKEYPTEIINPKI
CSDKTLAQIREILRKVVGEGLAKPAGSKQFHVSGKTGTAQVSQGAAGYKTGRTNYLVSFCGYFPSEEPKYSMIVSIQKPG
LPASGGLMAGSVFSKIAERVYAKDLRLPLTSAIDTNTVVIPNVKAGEMRETQRVLEELNIKIQGKITDSGKEVWGSTHPA
PQAVVLESRGIMQNFVPSVVGMGAKDAVYLLESKGLKVNLVGVGKVKSQSIANGSVARKGQTITLTLH
>Mature_707_residues
TRYFFVILIMALIGVAIVVKAGVTMFAERQYWQDVADRFVKENVTVKPNRGNIISSDGKLMASSLPEYRIYMDFMSGEKD
EKRRKKDQARRDSILKANMDSICIGLHKIFPDKSAAQFKAHLQKGRQAKSRNYLIYPKRISYIQYKEVKRLPVFCLNRYK
GGFKELAYNQRKKPFGSLAARTLGDVYADTAQGAKNGIELAFDTILKGRDGLTHRQKVMNKYLNIVDVAPIDGCDLITTI
DVGMQDICEKALVDKLKELNATVGVVVLMEVATGEVKAIVNMTQGRDGEYYEVRNNAISDMLEPGSTFKTASIMVALEDG
KITPDYIVDTGNGQKPMHGRVMKDHNWHRGGYGKLTVTEILGVSSNVGTSSIIENFYGSNPQKFVDGLKRMSIDQPLHLQ
ISGEGKPNIRGPKERYFSKTTLPWMSIGYETQVPPINILTFYNAIANNGVSIRPKFVKAAVRDGEVIKEYPTEIINPKIC
SDKTLAQIREILRKVVGEGLAKPAGSKQFHVSGKTGTAQVSQGAAGYKTGRTNYLVSFCGYFPSEEPKYSMIVSIQKPGL
PASGGLMAGSVFSKIAERVYAKDLRLPLTSAIDTNTVVIPNVKAGEMRETQRVLEELNIKIQGKITDSGKEVWGSTHPAP
QAVVLESRGIMQNFVPSVVGMGAKDAVYLLESKGLKVNLVGVGKVKSQSIANGSVARKGQTITLTLH

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=425, Percent_Identity=27.0588235294118, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 78090; Mature: 77959

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYFFVILIMALIGVAIVVKAGVTMFAERQYWQDVADRFVKENVTVKPNRGNIISSDGK
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEECCCCC
LMASSLPEYRIYMDFMSGEKDEKRRKKDQARRDSILKANMDSICIGLHKIFPDKSAAQFK
CHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHH
AHLQKGRQAKSRNYLIYPKRISYIQYKEVKRLPVFCLNRYKGGFKELAYNQRKKPFGSLA
HHHHHHHHHHCCCEEEECCCCCCEEHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCHHHHH
ARTLGDVYADTAQGAKNGIELAFDTILKGRDGLTHRQKVMNKYLNIVDVAPIDGCDLITT
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEECCCCCCCEEEE
IDVGMQDICEKALVDKLKELNATVGVVVLMEVATGEVKAIVNMTQGRDGEYYEVRNNAIS
HHCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCCCCCEEEEHHHHHH
DMLEPGSTFKTASIMVALEDGKITPDYIVDTGNGQKPMHGRVMKDHNWHRGGYGKLTVTE
HHHCCCCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCEEHHH
ILGVSSNVGTSSIIENFYGSNPQKFVDGLKRMSIDQPLHLQISGEGKPNIRGPKERYFSK
HHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHCC
TTLPWMSIGYETQVPPINILTFYNAIANNGVSIRPKFVKAAVRDGEVIKEYPTEIINPKI
CCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHCCCHHHHHCCHHHCCCCC
CSDKTLAQIREILRKVVGEGLAKPAGSKQFHVSGKTGTAQVSQGAAGYKTGRTNYLVSFC
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
GYFPSEEPKYSMIVSIQKPGLPASGGLMAGSVFSKIAERVYAKDLRLPLTSAIDTNTVVI
HCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEE
PNVKAGEMRETQRVLEELNIKIQGKITDSGKEVWGSTHPAPQAVVLESRGIMQNFVPSVV
CCCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
GMGAKDAVYLLESKGLKVNLVGVGKVKSQSIANGSVARKGQTITLTLH
CCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
TRYFFVILIMALIGVAIVVKAGVTMFAERQYWQDVADRFVKENVTVKPNRGNIISSDGK
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEECCCCC
LMASSLPEYRIYMDFMSGEKDEKRRKKDQARRDSILKANMDSICIGLHKIFPDKSAAQFK
CHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHH
AHLQKGRQAKSRNYLIYPKRISYIQYKEVKRLPVFCLNRYKGGFKELAYNQRKKPFGSLA
HHHHHHHHHHCCCEEEECCCCCCEEHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCHHHHH
ARTLGDVYADTAQGAKNGIELAFDTILKGRDGLTHRQKVMNKYLNIVDVAPIDGCDLITT
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEECCCCCCCEEEE
IDVGMQDICEKALVDKLKELNATVGVVVLMEVATGEVKAIVNMTQGRDGEYYEVRNNAIS
HHCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCCCCCEEEEHHHHHH
DMLEPGSTFKTASIMVALEDGKITPDYIVDTGNGQKPMHGRVMKDHNWHRGGYGKLTVTE
HHHCCCCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCEEHHH
ILGVSSNVGTSSIIENFYGSNPQKFVDGLKRMSIDQPLHLQISGEGKPNIRGPKERYFSK
HHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHCC
TTLPWMSIGYETQVPPINILTFYNAIANNGVSIRPKFVKAAVRDGEVIKEYPTEIINPKI
CCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHCCCHHHHHCCHHHCCCCC
CSDKTLAQIREILRKVVGEGLAKPAGSKQFHVSGKTGTAQVSQGAAGYKTGRTNYLVSFC
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
GYFPSEEPKYSMIVSIQKPGLPASGGLMAGSVFSKIAERVYAKDLRLPLTSAIDTNTVVI
HCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEE
PNVKAGEMRETQRVLEELNIKIQGKITDSGKEVWGSTHPAPQAVVLESRGIMQNFVPSVV
CCCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
GMGAKDAVYLLESKGLKVNLVGVGKVKSQSIANGSVARKGQTITLTLH
CCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]