Click here to switch to the map view.

The map label for this gene is mraY [H]

Identifier: 29348860

GI number: 29348860

Start: 4445765

End: 4447033

Strand: Reverse

Name: mraY [H]

Synonym: BT_3451

Alternate gene names: 29348860

Gene position: 4447033-4445765 (Counterclockwise)

Preceding gene: 29348861

Following gene: 29348859

Centisome position: 71.03

GC content: 45.31

Gene sequence:

>1269_bases
ATGTTATACTATCTGTTTGAATGGCTGCACAAGCTTAATTTTCCCGGAGCGGGAATGTTCGGTTACACCTCATTCCGTGC
TTTGATGGCTGTTATCCTCGCATTGCTTATATCGAGTATATGGGGAGACAAATTCATCAATCTGCTTAAAAAGAAGCAAA
TCACGGAAACACAGCGTGACGCCAAGACCGACCCGTTCGGTGTCAACAAAGTAGGCGTACCAAGCATGGGAGGTGTCATC
ATCATTGTAGCCATCCTTATACCTTGCCTGCTATTGGGTAAGCTGGATAATATATACATGATATTGATGCTGATCACCAC
TGTATGGCTGGGATCACTCGGTTTTGCCGACGACTATATCAAAATATTCAAGAAAGACAAGGAAGGCTTGCACGGTAAGT
TCAAAATCATCGGTCAGGTGGGTCTGGGGCTGATTGTAGGCTTAACCCTGTATCTGAGTCCGGATGTAGTTATCCGCGAA
AACATCGAGGTTCATACACCGGGACAGGAAATGGAAGTGATTCACGGAACCAATGATTTAAAATCTACCCAAACCACTAT
TCCTTTCTTTAAAAGTAACAACTTAGATTATGCCGACCTGGTGGGCTTTATGGGCGAACATGCACAGACAGCCGGATGGT
TCCTGTTCGTGATCATTACGATCTTCGTTGTAACCGCCGTTTCGAACGGGGCTAACCTGAATGACGGCATGGACGGTATG
GCAGCCGGAAACTCCGCCATTATCGGTGCCACGCTGGGAATACTGGCGTACGTATCGTCACACATCGAATTTGCCAGCTA
TCTGAATATCATGTACATTCCGGGATCGGAAGAACTGGTAATCTACATTTGTGCCTTTATCGGTGCATTGATCGGTTTCT
TATGGTACAACGCCTATCCGGCACAAGTATTCATGGGAGACACAGGCAGCCTGACTATCGGTGGTATCATTGCCGTATTT
GCCATTATCATCCACAAAGAATTGCTGATACCGATTCTCTGCGGTGTATTTCTGGTAGAGAATCTGTCAGTCATACTGCA
ACGCTTCTACTATAAGATAGGTAAGCGGAAGGGAGTAAAACAGCGGTTATTCAAACGAACTCCGATACACGATCATTTCC
GTACTTCGATGAGTCTGGTAGAACCGGGATGTACGGTGAAGTTCACGAAGCCCGACCAGCTATTTCACGAATCAAAGATT
ACCGTCCGTTTCTGGATTGTAACGATTGTACTGGCAGCGATAACGATTATTACATTAAAAATACGATGA

Upstream 100 bases:

>100_bases
TGACAACATATAATTATTTGCAATAGACAGCATCTTATCAAGCGTGGGGCAACAATGAGAAACTGTAAATTGCAGGCTAT
AAATTGTAAATAGAAAAGAG

Downstream 100 bases:

>100_bases
GAACAAACAGACTGCCCAATGCAGGATATTTGTAACATTAATATAGTTGAGAGTATTAACCCGATTATTAACTTTAAAAA
GATGTGCGCAGCCGACGAGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MLYYLFEWLHKLNFPGAGMFGYTSFRALMAVILALLISSIWGDKFINLLKKKQITETQRDAKTDPFGVNKVGVPSMGGVI
IIVAILIPCLLLGKLDNIYMILMLITTVWLGSLGFADDYIKIFKKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPDVVIRE
NIEVHTPGQEMEVIHGTNDLKSTQTTIPFFKSNNLDYADLVGFMGEHAQTAGWFLFVIITIFVVTAVSNGANLNDGMDGM
AAGNSAIIGATLGILAYVSSHIEFASYLNIMYIPGSEELVIYICAFIGALIGFLWYNAYPAQVFMGDTGSLTIGGIIAVF
AIIIHKELLIPILCGVFLVENLSVILQRFYYKIGKRKGVKQRLFKRTPIHDHFRTSMSLVEPGCTVKFTKPDQLFHESKI
TVRFWIVTIVLAAITIITLKIR

Sequences:

>Translated_422_residues
MLYYLFEWLHKLNFPGAGMFGYTSFRALMAVILALLISSIWGDKFINLLKKKQITETQRDAKTDPFGVNKVGVPSMGGVI
IIVAILIPCLLLGKLDNIYMILMLITTVWLGSLGFADDYIKIFKKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPDVVIRE
NIEVHTPGQEMEVIHGTNDLKSTQTTIPFFKSNNLDYADLVGFMGEHAQTAGWFLFVIITIFVVTAVSNGANLNDGMDGM
AAGNSAIIGATLGILAYVSSHIEFASYLNIMYIPGSEELVIYICAFIGALIGFLWYNAYPAQVFMGDTGSLTIGGIIAVF
AIIIHKELLIPILCGVFLVENLSVILQRFYYKIGKRKGVKQRLFKRTPIHDHFRTSMSLVEPGCTVKFTKPDQLFHESKI
TVRFWIVTIVLAAITIITLKIR
>Mature_422_residues
MLYYLFEWLHKLNFPGAGMFGYTSFRALMAVILALLISSIWGDKFINLLKKKQITETQRDAKTDPFGVNKVGVPSMGGVI
IIVAILIPCLLLGKLDNIYMILMLITTVWLGSLGFADDYIKIFKKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPDVVIRE
NIEVHTPGQEMEVIHGTNDLKSTQTTIPFFKSNNLDYADLVGFMGEHAQTAGWFLFVIITIFVVTAVSNGANLNDGMDGM
AAGNSAIIGATLGILAYVSSHIEFASYLNIMYIPGSEELVIYICAFIGALIGFLWYNAYPAQVFMGDTGSLTIGGIIAVF
AIIIHKELLIPILCGVFLVENLSVILQRFYYKIGKRKGVKQRLFKRTPIHDHFRTSMSLVEPGCTVKFTKPDQLFHESKI
TVRFWIVTIVLAAITIITLKIR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=423, Percent_Identity=34.2789598108747, Blast_Score=221, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 46833; Mature: 46833

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS01347 MRAY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYYLFEWLHKLNFPGAGMFGYTSFRALMAVILALLISSIWGDKFINLLKKKQITETQRD
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTDPFGVNKVGVPSMGGVIIIVAILIPCLLLGKLDNIYMILMLITTVWLGSLGFADDYI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHH
KIFKKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPDVVIRENIEVHTPGQEMEVIHGTNDL
HHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCEEEEECCCCC
KSTQTTIPFFKSNNLDYADLVGFMGEHAQTAGWFLFVIITIFVVTAVSNGANLNDGMDGM
CCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AAGNSAIIGATLGILAYVSSHIEFASYLNIMYIPGSEELVIYICAFIGALIGFLWYNAYP
CCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
AQVFMGDTGSLTIGGIIAVFAIIIHKELLIPILCGVFLVENLSVILQRFYYKIGKRKGVK
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QRLFKRTPIHDHFRTSMSLVEPGCTVKFTKPDQLFHESKITVRFWIVTIVLAAITIITLK
HHHHHCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEE
IR
EC
>Mature Secondary Structure
MLYYLFEWLHKLNFPGAGMFGYTSFRALMAVILALLISSIWGDKFINLLKKKQITETQRD
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTDPFGVNKVGVPSMGGVIIIVAILIPCLLLGKLDNIYMILMLITTVWLGSLGFADDYI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHH
KIFKKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPDVVIRENIEVHTPGQEMEVIHGTNDL
HHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCEEEEECCCCC
KSTQTTIPFFKSNNLDYADLVGFMGEHAQTAGWFLFVIITIFVVTAVSNGANLNDGMDGM
CCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AAGNSAIIGATLGILAYVSSHIEFASYLNIMYIPGSEELVIYICAFIGALIGFLWYNAYP
CCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
AQVFMGDTGSLTIGGIIAVFAIIIHKELLIPILCGVFLVENLSVILQRFYYKIGKRKGVK
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QRLFKRTPIHDHFRTSMSLVEPGCTVKFTKPDQLFHESKITVRFWIVTIVLAAITIITLK
HHHHHCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEE
IR
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA