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The map label for this gene is argS [H]

Identifier: 29348238

GI number: 29348238

Start: 3527081

End: 3528874

Strand: Reverse

Name: argS [H]

Synonym: BT_2829

Alternate gene names: 29348238

Gene position: 3528874-3527081 (Counterclockwise)

Preceding gene: 29348239

Following gene: 29348235

Centisome position: 56.37

GC content: 44.54

Gene sequence:

>1794_bases
ATGAAGATAGAAGATAAACTTGTAGCGTCCGTCATCAACGGACTAAAAGCACTTTACGGTCAGGAAGTCCCTGAGAAGAT
GGTGCAGTTGCAAAAAACGAAGAAAGAATTTGAAGGACATTTGACACTGGTCGTGTTCCCTTTTCTGAAAATGTCAAGAA
AAGGACCGGAACAGACAGCGCAGGAAATTGGCGAATATCTGAAGGCGAACGAACCGGCTGTAGCTGCTTTCAATGTAATA
AAAGGCTTTTTGAATCTGACTATTGCATCGGCTACCTGGATTGAGTTGCTGAATGAGATTCAGTCGGATGAAGAGTACGG
CCTGGTGAAAGCTACCGAAACTTCTCCGTTGGTGATGATTGAGTATTCTTCACCGAATACCAACAAGCCGCTTCACTTAG
GTCATGTGCGCAACAATCTTTTGGGAAATGCGCTGGCTAACATTGTGGCTGCAAACGGAAACAGAGTAGTAAAGACGAAT
ATAGTAAACGACCGTGGTATCCATATCTGCAAATCCATGCTGGCATGGAAGAAATACGGAAACGGCGAAACTCCTGAAAG
CACCGGCAAGAAAGGTGATCATCTGGTAGGCGACTACTATGTGTCTTTCGACAAGCATTATAAAGCGGAACTTGCCGAAC
TGATGGAAAAAGGCATGACGAAAGAGGAAGCGGAAGCTGCTTCTCCGTTGATGCAGGAAGCCCGCGAAATGTTGGTGAAA
TGGGAAGCCGGTGATCCGGAAGTACGTGCCCTGTGGGAGATGATGAACAACTGGGTGTATGCCGGATTTGATGAGACTTA
CCGGAAGATGGGGGTCGGCTTCGATAAGATATATTATGAATCCAATACTTATCTTGAAGGAAAAGAGAAAGTAATGGAGG
GACTGGAAAAAGGCTTTTTCTTCAAAAAAGAAGACGGCTCTGTCTGGGTTGACCTGACTGCCGAGGGGCTGGATCATAAG
CTGCTTCTTCGTGGCGATGGAACCTCTGTTTATATGACGCAGGATATTGGCACGGCCAAACTTCGTTTCGCTGATTATCC
GATTGATAAAATGATTTATGTCGTTGGTAACGAACAGAATTATCACTTCCAGGTACTTTCTATTCTGTTGGATAAACTCG
GTTTTGAATGGGGTAAAGGCCTTGTACATTTCTCTTATGGTATGGTAGAATTGCCGGAAGGTAAGATGAAATCTCGTGAA
GGAACAGTCGTTGATGCCGATGACCTGATGGAAGAGATGGTATCGACTGCAAAAGAAACTTCGCAGGAACTCGGAAAACT
GGATGGTCTGACGCAGGAAGAAGCAGATGATATTGCCCGTATTGTCGGTCTGGGTGCTTTGAAGTACTTTATTCTCAAAG
TAGATGCCCGTAAGAATATGACTTTCAATCCGAAAGAGTCTATCGACTTCAATGGTAATACAGGACCGTTCATTCAATAT
ACGTATGCCCGTATTCAGTCTGTGCTTCGTAAAGCGGCTGAGTCTGGAATTGTGATACCTGAACAGATTCCTGCTGGTAT
CGAACTGAGCGAGAAGGAAGAAGGATTGATTCAGTTGGTTGCTGACTTTGCGGCAGTTGTAAAACAGGCCGGAGAAGACT
ACAGTCCGTCTATTATCGCGAATTATACCTATGATCTGGTGAAAGAATATAATCAGTTCTACCATGATTTCAGCATTCTG
CGTGAAGAGAATGAGGCGGTAAAAGTATTCCGTATTGCTCTGTCTGCCAATGTAGCAAAAGTGGTTCGTTTAGGAATGGG
CTTGTTGGGCATTGAGGTACCTTCCAGAATGTAA

Upstream 100 bases:

>100_bases
TCTGCAGCTGTTGAATAAACATATAGTTGAAAGAAATTAGAAGAGGGAGGCGCGTGCGTCTCCTTTTTTTGTATCTTTGC
GCGCAAGAAACAACTTGATT

Downstream 100 bases:

>100_bases
TACCTGCCCTGAACAAAATATATTTATGTGTTCCGGAACGGGACTGGGATGTTGTTGAATAGAAAAAGACTGTCCGAAAA
GGAATTGTACTCTATCTTTA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MKIEDKLVASVINGLKALYGQEVPEKMVQLQKTKKEFEGHLTLVVFPFLKMSRKGPEQTAQEIGEYLKANEPAVAAFNVI
KGFLNLTIASATWIELLNEIQSDEEYGLVKATETSPLVMIEYSSPNTNKPLHLGHVRNNLLGNALANIVAANGNRVVKTN
IVNDRGIHICKSMLAWKKYGNGETPESTGKKGDHLVGDYYVSFDKHYKAELAELMEKGMTKEEAEAASPLMQEAREMLVK
WEAGDPEVRALWEMMNNWVYAGFDETYRKMGVGFDKIYYESNTYLEGKEKVMEGLEKGFFFKKEDGSVWVDLTAEGLDHK
LLLRGDGTSVYMTQDIGTAKLRFADYPIDKMIYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSRE
GTVVDADDLMEEMVSTAKETSQELGKLDGLTQEEADDIARIVGLGALKYFILKVDARKNMTFNPKESIDFNGNTGPFIQY
TYARIQSVLRKAAESGIVIPEQIPAGIELSEKEEGLIQLVADFAAVVKQAGEDYSPSIIANYTYDLVKEYNQFYHDFSIL
REENEAVKVFRIALSANVAKVVRLGMGLLGIEVPSRM

Sequences:

>Translated_597_residues
MKIEDKLVASVINGLKALYGQEVPEKMVQLQKTKKEFEGHLTLVVFPFLKMSRKGPEQTAQEIGEYLKANEPAVAAFNVI
KGFLNLTIASATWIELLNEIQSDEEYGLVKATETSPLVMIEYSSPNTNKPLHLGHVRNNLLGNALANIVAANGNRVVKTN
IVNDRGIHICKSMLAWKKYGNGETPESTGKKGDHLVGDYYVSFDKHYKAELAELMEKGMTKEEAEAASPLMQEAREMLVK
WEAGDPEVRALWEMMNNWVYAGFDETYRKMGVGFDKIYYESNTYLEGKEKVMEGLEKGFFFKKEDGSVWVDLTAEGLDHK
LLLRGDGTSVYMTQDIGTAKLRFADYPIDKMIYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSRE
GTVVDADDLMEEMVSTAKETSQELGKLDGLTQEEADDIARIVGLGALKYFILKVDARKNMTFNPKESIDFNGNTGPFIQY
TYARIQSVLRKAAESGIVIPEQIPAGIELSEKEEGLIQLVADFAAVVKQAGEDYSPSIIANYTYDLVKEYNQFYHDFSIL
REENEAVKVFRIALSANVAKVVRLGMGLLGIEVPSRM
>Mature_597_residues
MKIEDKLVASVINGLKALYGQEVPEKMVQLQKTKKEFEGHLTLVVFPFLKMSRKGPEQTAQEIGEYLKANEPAVAAFNVI
KGFLNLTIASATWIELLNEIQSDEEYGLVKATETSPLVMIEYSSPNTNKPLHLGHVRNNLLGNALANIVAANGNRVVKTN
IVNDRGIHICKSMLAWKKYGNGETPESTGKKGDHLVGDYYVSFDKHYKAELAELMEKGMTKEEAEAASPLMQEAREMLVK
WEAGDPEVRALWEMMNNWVYAGFDETYRKMGVGFDKIYYESNTYLEGKEKVMEGLEKGFFFKKEDGSVWVDLTAEGLDHK
LLLRGDGTSVYMTQDIGTAKLRFADYPIDKMIYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSRE
GTVVDADDLMEEMVSTAKETSQELGKLDGLTQEEADDIARIVGLGALKYFILKVDARKNMTFNPKESIDFNGNTGPFIQY
TYARIQSVLRKAAESGIVIPEQIPAGIELSEKEEGLIQLVADFAAVVKQAGEDYSPSIIANYTYDLVKEYNQFYHDFSIL
REENEAVKVFRIALSANVAKVVRLGMGLLGIEVPSRM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=489, Percent_Identity=27.4028629856851, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI15149476, Length=576, Percent_Identity=22.5694444444444, Blast_Score=126, Evalue=6e-29,
Organism=Escherichia coli, GI1788184, Length=555, Percent_Identity=27.7477477477477, Blast_Score=182, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71985061, Length=567, Percent_Identity=23.2804232804233, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17532153, Length=510, Percent_Identity=22.3529411764706, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71985068, Length=536, Percent_Identity=22.9477611940299, Blast_Score=103, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320548, Length=576, Percent_Identity=28.2986111111111, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6321883, Length=489, Percent_Identity=26.7893660531697, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28571570, Length=508, Percent_Identity=24.2125984251968, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI18859963, Length=586, Percent_Identity=23.2081911262799, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 66954; Mature: 66954

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEDKLVASVINGLKALYGQEVPEKMVQLQKTKKEFEGHLTLVVFPFLKMSRKGPEQTA
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCHHHHH
QEIGEYLKANEPAVAAFNVIKGFLNLTIASATWIELLNEIQSDEEYGLVKATETSPLVMI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEE
EYSSPNTNKPLHLGHVRNNLLGNALANIVAANGNRVVKTNIVNDRGIHICKSMLAWKKYG
EECCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHCC
NGETPESTGKKGDHLVGDYYVSFDKHYKAELAELMEKGMTKEEAEAASPLMQEAREMLVK
CCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEE
WEAGDPEVRALWEMMNNWVYAGFDETYRKMGVGFDKIYYESNTYLEGKEKVMEGLEKGFF
CCCCCHHHHHHHHHHHCCEEECHHHHHHHHCCCHHHEEECCCCEECCHHHHHHHHHHCCE
FKKEDGSVWVDLTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFADYPIDKMIYVVGNEQN
EEECCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCEEEEEECCCC
YHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSREGTVVDADDLMEEMVSTAKET
CHHHHHHHHHHHHCHHHCCCEEEEECCCEECCCCCCCCCCCCEECHHHHHHHHHHHHHHH
SQELGKLDGLTQEEADDIARIVGLGALKYFILKVDARKNMTFNPKESIDFNGNTGPFIQY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCHH
TYARIQSVLRKAAESGIVIPEQIPAGIELSEKEEGLIQLVADFAAVVKQAGEDYSPSIIA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
NYTYDLVKEYNQFYHDFSILREENEAVKVFRIALSANVAKVVRLGMGLLGIEVPSRM
HHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure
MKIEDKLVASVINGLKALYGQEVPEKMVQLQKTKKEFEGHLTLVVFPFLKMSRKGPEQTA
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCHHHHH
QEIGEYLKANEPAVAAFNVIKGFLNLTIASATWIELLNEIQSDEEYGLVKATETSPLVMI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEE
EYSSPNTNKPLHLGHVRNNLLGNALANIVAANGNRVVKTNIVNDRGIHICKSMLAWKKYG
EECCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHCC
NGETPESTGKKGDHLVGDYYVSFDKHYKAELAELMEKGMTKEEAEAASPLMQEAREMLVK
CCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEE
WEAGDPEVRALWEMMNNWVYAGFDETYRKMGVGFDKIYYESNTYLEGKEKVMEGLEKGFF
CCCCCHHHHHHHHHHHCCEEECHHHHHHHHCCCHHHEEECCCCEECCHHHHHHHHHHCCE
FKKEDGSVWVDLTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFADYPIDKMIYVVGNEQN
EEECCCCEEEEEEECCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCEEEEEECCCC
YHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSREGTVVDADDLMEEMVSTAKET
CHHHHHHHHHHHHCHHHCCCEEEEECCCEECCCCCCCCCCCCEECHHHHHHHHHHHHHHH
SQELGKLDGLTQEEADDIARIVGLGALKYFILKVDARKNMTFNPKESIDFNGNTGPFIQY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCHH
TYARIQSVLRKAAESGIVIPEQIPAGIELSEKEEGLIQLVADFAAVVKQAGEDYSPSIIA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
NYTYDLVKEYNQFYHDFSILREENEAVKVFRIALSANVAKVVRLGMGLLGIEVPSRM
HHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA