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The map label for this gene is cusB [H]

Identifier: 29348096

GI number: 29348096

Start: 3349011

End: 3350027

Strand: Reverse

Name: cusB [H]

Synonym: BT_2687

Alternate gene names: 29348096

Gene position: 3350027-3349011 (Counterclockwise)

Preceding gene: 29348097

Following gene: 29348095

Centisome position: 53.51

GC content: 48.28

Gene sequence:

>1017_bases
ATGAAAAAAGGTATCCAATTAGTGGCTCTGCTATTGACAGTAGTAATGAGCTCATGTACGGGTGGAAAAGATAAGGCTGC
TGTGAAACAGGAAGACGAGAAGCCCAGAGTAAAAGTGGCTGATGTAACAGCCCGTCCCGTAGATCAGATACAGGATTATA
CAGCGACGGTAGAAGCTGAAGTAAAGAACAACATTGCTCCTTCGTCACCTGTCCGCATCGACCGGATTCTGGTAGAAGTG
GGCGACCGTGTATCCAAAGGCCAGAAGCTGGTGCAGATGGATGCAGCCAACCTCACACAGACGAAACTGCAACTGGACAA
TCAGAAAATTGAATTTAATCGTATCGACGAACTTTATAAGGTAGGCGGTGCTTCCAAATCAGAGTGGGATGCTGCGAAGA
TGCAGCTCGATGTGAAGCAGACTGCTTATGATAATCTGGTAGAGAATACGTTTCTGTTGAGCCCGATCAACGGAGTAATC
ACTGCCCGTAATTACGATAATGGTGATATGTATAGTGGCGGAAGTCCGGTGCTGGTAGTAGAGCAGATCACTCCGGTCAA
GCTGATGATCAATGTGTCTGAAACCTACTTCACGAAGGTGAAGAAAGGCGAACCGGTAGATGTGAAGCTGGATGTATATG
GCGACGAACTGTTCAAGGGAACTATCAGCCTGATCTATCCGACTATCGACGCAACTACCCGTACTTTCCAGATCGAGATC
AAGTTGGACAACAAAGATCAGCGTGTACGTCCGGGAATGTTTGCCCGTGCTACCTTGAACTTCGGTACGGCGGACAACGT
CGTAGTACCCGACTTGGCTATTGTGAAACAGGCAGGTTCCGGCGATCGCTATGTGTACGTTTATAAAGATGGCAAAGTGT
CCTACAACAAAGTGGAGTTAGGCAGACGTATGGGCTCGGAGTATGAGCTGAAATCCGGTGTGCCCGATAACTCGCAGGTG
GTAGTGGCCGGACAGGCACGTCTGATAAACGGTACGGAAGTAGAGATCGAGAAGTAA

Upstream 100 bases:

>100_bases
TACAATCAATCAATCTACGATTACCTGGTAGCTAAGGCTGACCTTGATCAGGTTTTGGGAAAACAATAAAGATAGACAAC
TAAAATTACAACTAAGGAAT

Downstream 100 bases:

>100_bases
AATCACTATTAAACTAATCACTATAAAGAAATGAGTTTATACGAAGGTGCGGTTAAGAAACCGATTATGACCTCCCTCTG
CTTTCTGGCAGTGGTGATTT

Product: cation efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKKGIQLVALLLTVVMSSCTGGKDKAAVKQEDEKPRVKVADVTARPVDQIQDYTATVEAEVKNNIAPSSPVRIDRILVEV
GDRVSKGQKLVQMDAANLTQTKLQLDNQKIEFNRIDELYKVGGASKSEWDAAKMQLDVKQTAYDNLVENTFLLSPINGVI
TARNYDNGDMYSGGSPVLVVEQITPVKLMINVSETYFTKVKKGEPVDVKLDVYGDELFKGTISLIYPTIDATTRTFQIEI
KLDNKDQRVRPGMFARATLNFGTADNVVVPDLAIVKQAGSGDRYVYVYKDGKVSYNKVELGRRMGSEYELKSGVPDNSQV
VVAGQARLINGTEVEIEK

Sequences:

>Translated_338_residues
MKKGIQLVALLLTVVMSSCTGGKDKAAVKQEDEKPRVKVADVTARPVDQIQDYTATVEAEVKNNIAPSSPVRIDRILVEV
GDRVSKGQKLVQMDAANLTQTKLQLDNQKIEFNRIDELYKVGGASKSEWDAAKMQLDVKQTAYDNLVENTFLLSPINGVI
TARNYDNGDMYSGGSPVLVVEQITPVKLMINVSETYFTKVKKGEPVDVKLDVYGDELFKGTISLIYPTIDATTRTFQIEI
KLDNKDQRVRPGMFARATLNFGTADNVVVPDLAIVKQAGSGDRYVYVYKDGKVSYNKVELGRRMGSEYELKSGVPDNSQV
VVAGQARLINGTEVEIEK
>Mature_338_residues
MKKGIQLVALLLTVVMSSCTGGKDKAAVKQEDEKPRVKVADVTARPVDQIQDYTATVEAEVKNNIAPSSPVRIDRILVEV
GDRVSKGQKLVQMDAANLTQTKLQLDNQKIEFNRIDELYKVGGASKSEWDAAKMQLDVKQTAYDNLVENTFLLSPINGVI
TARNYDNGDMYSGGSPVLVVEQITPVKLMINVSETYFTKVKKGEPVDVKLDVYGDELFKGTISLIYPTIDATTRTFQIEI
KLDNKDQRVRPGMFARATLNFGTADNVVVPDLAIVKQAGSGDRYVYVYKDGKVSYNKVELGRRMGSEYELKSGVPDNSQV
VVAGQARLINGTEVEIEK

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=299, Percent_Identity=25.0836120401338, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789929, Length=363, Percent_Identity=24.5179063360882, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082036, Length=300, Percent_Identity=25.3333333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786668, Length=377, Percent_Identity=23.6074270557029, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37305; Mature: 37305

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGIQLVALLLTVVMSSCTGGKDKAAVKQEDEKPRVKVADVTARPVDQIQDYTATVEAE
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHEEEEEE
VKNNIAPSSPVRIDRILVEVGDRVSKGQKLVQMDAANLTQTKLQLDNQKIEFNRIDELYK
HHCCCCCCCCCHHHHHHHHHCCHHHCCCEEEEECCCCCEEEEEEECCCEEEHHHHHHHHH
VGGASKSEWDAAKMQLDVKQTAYDNLVENTFLLSPINGVITARNYDNGDMYSGGSPVLVV
HCCCCCCCCCHHHEEEEHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCCCCEEEE
EQITPVKLMINVSETYFTKVKKGEPVDVKLDVYGDELFKGTISLIYPTIDATTRTFQIEI
ECCCCEEEEEEECHHHHHHHCCCCCCEEEEEECCCCHHHCEEEEEEEECCCCEEEEEEEE
KLDNKDQRVRPGMFARATLNFGTADNVVVPDLAIVKQAGSGDRYVYVYKDGKVSYNKVEL
EECCCCCCCCCCEEEEEEEECCCCCCEECCCHHEEEECCCCCEEEEEEECCCEEEHHHHH
GRRMGSEYELKSGVPDNSQVVVAGQARLINGTEVEIEK
HHHCCCCEEECCCCCCCCEEEEECCEEEECCCEEEEEC
>Mature Secondary Structure
MKKGIQLVALLLTVVMSSCTGGKDKAAVKQEDEKPRVKVADVTARPVDQIQDYTATVEAE
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHEEEEEE
VKNNIAPSSPVRIDRILVEVGDRVSKGQKLVQMDAANLTQTKLQLDNQKIEFNRIDELYK
HHCCCCCCCCCHHHHHHHHHCCHHHCCCEEEEECCCCCEEEEEEECCCEEEHHHHHHHHH
VGGASKSEWDAAKMQLDVKQTAYDNLVENTFLLSPINGVITARNYDNGDMYSGGSPVLVV
HCCCCCCCCCHHHEEEEHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCCCCEEEE
EQITPVKLMINVSETYFTKVKKGEPVDVKLDVYGDELFKGTISLIYPTIDATTRTFQIEI
ECCCCEEEEEEECHHHHHHHCCCCCCEEEEEECCCCHHHCEEEEEEEECCCCEEEEEEEE
KLDNKDQRVRPGMFARATLNFGTADNVVVPDLAIVKQAGSGDRYVYVYKDGKVSYNKVEL
EECCCCCCCCCCEEEEEEEECCCCCCEECCCHHEEEECCCCCEEEEEEECCCEEEHHHHH
GRRMGSEYELKSGVPDNSQVVVAGQARLINGTEVEIEK
HHHCCCCEEECCCCCCCCEEEEECCEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]