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The map label for this gene is kinB [H]

Identifier: 29347830

GI number: 29347830

Start: 3022441

End: 3023889

Strand: Reverse

Name: kinB [H]

Synonym: BT_2420

Alternate gene names: 29347830

Gene position: 3023889-3022441 (Counterclockwise)

Preceding gene: 29347831

Following gene: 29347829

Centisome position: 48.3

GC content: 44.44

Gene sequence:

>1449_bases
ATGAACGATATGAATATTAAAACAAAACTGATTCTCGGCATCGGGATGCTGGCGGGAATGATTATTTTGCTGGTAACACT
TTCTGTTGTGAACCTTCAGCTGCTGACTGCCACAGAACCTGATAGCCCTGCCGCTATGCCGGCATTGGAACGCGCTCTGT
TGTGGATTTCCGTTACCGGCGGTATTTGTATATTGACCGGATTGACATTGCTGTATTGGTTGCCCCGAACAATCAGTAAA
CCCATCAAGGAACTGAAACAAGGGATTCTTGAAATAGCCAATCATAATTATGAAGAACGGCTGGATATGAGAAATAATCA
GGAGTTTCGGGAAGTCGCCGAGAGTTTCAACCGTATGGCGGAACGTCTGGCCGAGTATCGGGCAAGTACGTTAGCAGATA
TTCTTTCTGCCAAGAAATTCATTGAGGCCATCGTGAACAGTATCGACGATCCGATAATCGGTCTGAATATGGATCGTGAG
ATTTTGTTTATTAATGAGGAAGCACTGAACGTGCTGAATCTGAAAAGAGGTAATGTCATACGTAAATCTGCGGAAGAATT
GTCTTTGAAGAATGATCTGCTTCGCCGGCTGATTCGTGAACTGGTGACGCCGGGAGATCAGAAAGAGCCGTTAAAGATAT
ATGCCGATGATAAAGAGAGTTATTTCAAGGCTTCCTATATTCCTATCATAAATACGGATGCAGGGAAGGATGAACCCAGC
AAATTAGGGGATGTCATTCTGCTGAAGAATATAACGGAATTCAAGGAACTGGATTCTGCCAAGACTACATTTATTTCGAC
CATTTCACACGAATTGAAAACTCCGATTGCGGCTATCATGATGAGTCTGCAGCTATTGGAAGATAAACGTGTCGGTGAGC
TGAATGATGAACAGGAACAGTTGTCCAAAAGCATCAAGGAAAATAGCGAACGCCTGTTGAGCATTACGGGCGAATTGCTG
AATATGACTCAGGTAGAGGCAGGCAAGCTGCAATTAATGCCGAAGATAACGAAGCCCATTGAACTGATAGAATATGCGAT
TAAAGCTAATCAGGTACAAGCGGATAAGTTCAATATCCAGATAGAAGTAGAGTACCCGGAAGAGAAAATCGGCAAGCTCT
TTGTCGATAGTGAAAAGATAGCTTGGGTATTGACTAATTTGCTCAGCAATGCGATCCGTTATTCTAAAGAAAACGGGCGT
GTCGTGATTGGCGCCAGGCAGGAAGGAGATATGATCGACCTGTACGTTCAGGATTTCGGTAAAGGCATCGATCCCCGTTA
CCACAAGAGTATTTTCGACCGTTACTTCCGTGTTCCCGGAACAAAAGTTCAGGGCAGCGGACTCGGTTTGTCTATTTCGA
GAGACTTTGTGGAAGCGCATGGCGGTACGCTGACAGTAGAAAGTGAACTGGGAAAAGGAAGTCGGTTTGTGATGCGACTG
AAAGCATAA

Upstream 100 bases:

>100_bases
TTTCCTCATGCCATTTGCTCCATACTCGGATATCGAAAGTTTTTGAATAATTTGTCACAAGCTAATGTAGATTTGATTAT
ACTTGCATAATATTAACCGT

Downstream 100 bases:

>100_bases
AAGAGAATGTTCGGAAAGTGTCCGAGGCGGTTGCTGTGATAAATAAATGTGGTAGCTGATTTAATTTGAAATGAAACTTT
GGGAATCAAGACATTGCAGC

Product: two-component system histidine kinase, FrrD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MNDMNIKTKLILGIGMLAGMIILLVTLSVVNLQLLTATEPDSPAAMPALERALLWISVTGGICILTGLTLLYWLPRTISK
PIKELKQGILEIANHNYEERLDMRNNQEFREVAESFNRMAERLAEYRASTLADILSAKKFIEAIVNSIDDPIIGLNMDRE
ILFINEEALNVLNLKRGNVIRKSAEELSLKNDLLRRLIRELVTPGDQKEPLKIYADDKESYFKASYIPIINTDAGKDEPS
KLGDVILLKNITEFKELDSAKTTFISTISHELKTPIAAIMMSLQLLEDKRVGELNDEQEQLSKSIKENSERLLSITGELL
NMTQVEAGKLQLMPKITKPIELIEYAIKANQVQADKFNIQIEVEYPEEKIGKLFVDSEKIAWVLTNLLSNAIRYSKENGR
VVIGARQEGDMIDLYVQDFGKGIDPRYHKSIFDRYFRVPGTKVQGSGLGLSISRDFVEAHGGTLTVESELGKGSRFVMRL
KA

Sequences:

>Translated_482_residues
MNDMNIKTKLILGIGMLAGMIILLVTLSVVNLQLLTATEPDSPAAMPALERALLWISVTGGICILTGLTLLYWLPRTISK
PIKELKQGILEIANHNYEERLDMRNNQEFREVAESFNRMAERLAEYRASTLADILSAKKFIEAIVNSIDDPIIGLNMDRE
ILFINEEALNVLNLKRGNVIRKSAEELSLKNDLLRRLIRELVTPGDQKEPLKIYADDKESYFKASYIPIINTDAGKDEPS
KLGDVILLKNITEFKELDSAKTTFISTISHELKTPIAAIMMSLQLLEDKRVGELNDEQEQLSKSIKENSERLLSITGELL
NMTQVEAGKLQLMPKITKPIELIEYAIKANQVQADKFNIQIEVEYPEEKIGKLFVDSEKIAWVLTNLLSNAIRYSKENGR
VVIGARQEGDMIDLYVQDFGKGIDPRYHKSIFDRYFRVPGTKVQGSGLGLSISRDFVEAHGGTLTVESELGKGSRFVMRL
KA
>Mature_482_residues
MNDMNIKTKLILGIGMLAGMIILLVTLSVVNLQLLTATEPDSPAAMPALERALLWISVTGGICILTGLTLLYWLPRTISK
PIKELKQGILEIANHNYEERLDMRNNQEFREVAESFNRMAERLAEYRASTLADILSAKKFIEAIVNSIDDPIIGLNMDRE
ILFINEEALNVLNLKRGNVIRKSAEELSLKNDLLRRLIRELVTPGDQKEPLKIYADDKESYFKASYIPIINTDAGKDEPS
KLGDVILLKNITEFKELDSAKTTFISTISHELKTPIAAIMMSLQLLEDKRVGELNDEQEQLSKSIKENSERLLSITGELL
NMTQVEAGKLQLMPKITKPIELIEYAIKANQVQADKFNIQIEVEYPEEKIGKLFVDSEKIAWVLTNLLSNAIRYSKENGR
VVIGARQEGDMIDLYVQDFGKGIDPRYHKSIFDRYFRVPGTKVQGSGLGLSISRDFVEAHGGTLTVESELGKGSRFVMRL
KA

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=400, Percent_Identity=28.25, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=32.618025751073, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87081816, Length=230, Percent_Identity=32.6086956521739, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=29.6943231441048, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=24.4725738396624, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=28.6324786324786, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082128, Length=258, Percent_Identity=27.906976744186, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=27.5590551181102, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=26.2008733624454, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=204, Percent_Identity=26.9607843137255, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788549, Length=386, Percent_Identity=22.5388601036269, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=26.1802575107296, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=27.3542600896861, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=232, Percent_Identity=25.4310344827586, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54241; Mature: 54241

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMNIKTKLILGIGMLAGMIILLVTLSVVNLQLLTATEPDSPAAMPALERALLWISVTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHEEEEEECC
GICILTGLTLLYWLPRTISKPIKELKQGILEIANHNYEERLDMRNNQEFREVAESFNRMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHH
ERLAEYRASTLADILSAKKFIEAIVNSIDDPIIGLNMDREILFINEEALNVLNLKRGNVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHCCCCCHH
RKSAEELSLKNDLLRRLIRELVTPGDQKEPLKIYADDKESYFKASYIPIINTDAGKDEPS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHEEEEECEEEECCCCCCCHH
KLGDVILLKNITEFKELDSAKTTFISTISHELKTPIAAIMMSLQLLEDKRVGELNDEQEQ
HHCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHH
LSKSIKENSERLLSITGELLNMTQVEAGKLQLMPKITKPIELIEYAIKANQVQADKFNIQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCEEECEEEEE
IEVEYPEEKIGKLFVDSEKIAWVLTNLLSNAIRYSKENGRVVIGARQEGDMIDLYVQDFG
EEEECCHHHHCCEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEHHHHC
KGIDPRYHKSIFDRYFRVPGTKVQGSGLGLSISRDFVEAHGGTLTVESELGKGSRFVMRL
CCCCHHHHHHHHHHHHCCCCCEECCCCCEEEEEHHHHHHCCCEEEEECCCCCCCEEEEEE
KA
CC
>Mature Secondary Structure
MNDMNIKTKLILGIGMLAGMIILLVTLSVVNLQLLTATEPDSPAAMPALERALLWISVTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHEEEEEECC
GICILTGLTLLYWLPRTISKPIKELKQGILEIANHNYEERLDMRNNQEFREVAESFNRMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHH
ERLAEYRASTLADILSAKKFIEAIVNSIDDPIIGLNMDREILFINEEALNVLNLKRGNVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHCCCCCHH
RKSAEELSLKNDLLRRLIRELVTPGDQKEPLKIYADDKESYFKASYIPIINTDAGKDEPS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHEEEEECEEEECCCCCCCHH
KLGDVILLKNITEFKELDSAKTTFISTISHELKTPIAAIMMSLQLLEDKRVGELNDEQEQ
HHCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHH
LSKSIKENSERLLSITGELLNMTQVEAGKLQLMPKITKPIELIEYAIKANQVQADKFNIQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCEEECEEEEE
IEVEYPEEKIGKLFVDSEKIAWVLTNLLSNAIRYSKENGRVVIGARQEGDMIDLYVQDFG
EEEECCHHHHCCEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEHHHHC
KGIDPRYHKSIFDRYFRVPGTKVQGSGLGLSISRDFVEAHGGTLTVESELGKGSRFVMRL
CCCCHHHHHHHHHHHHCCCCCEECCCCCEEEEEHHHHHHCCCEEEEECCCCCCCEEEEEE
KA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]