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The map label for this gene is tadA [H]

Identifier: 29347644

GI number: 29347644

Start: 2803099

End: 2803542

Strand: Reverse

Name: tadA [H]

Synonym: BT_2234

Alternate gene names: 29347644

Gene position: 2803542-2803099 (Counterclockwise)

Preceding gene: 29347645

Following gene: 29347640

Centisome position: 44.78

GC content: 49.77

Gene sequence:

>444_bases
ATGATGACGCTGGACGATACTTACTTCATGAAACAGGCATTGATAGAAGCCGGCAAGGCTGCAGAGCGGGGCGAAGTCCC
TGTAGGGGCAGTGGTTGTCTGCAAAGAACGGATCATAGCCCGTGCCCATAACCTGACAGAAACATTGAATGATGTGACAG
CCCATGCTGAAATGCAGGCTATCACTGCTGCCGCCAATGTACTTGGCGGAAAGTACCTGAACGAATGTACGTTGTATGTT
ACAGTAGAACCCTGTGTGATGTGTGCCGGTGCCATTGCTTGGGCTCAGACCGGCAAACTGGTTTTTGGTGCGGAAGATGA
TAAGCGTGGGTATCAGCGATATGCGGCTCAGGCGCTGCATCCTAAAACGGTCGTTGTAAAAGGAATCCTTGCAGATGAAT
GTGCCACATTGATGAAGGACTTTTTCGCTTCTAAGAGAAGATGA

Upstream 100 bases:

>100_bases
ATAAGTCACGCTGGCTTCGCGAAACCATTCTCATGTTTATCCATAAAAATATGGAAGAAGATTATCCTACCCTCTTCGGA
GAACATGACATGAGACGCTG

Downstream 100 bases:

>100_bases
AACAGTGATTAGTAAGTTGCTGACTACACGTTACTAACCACTTTCTATATTATATTATTTTACTTCCTCGAAATCCACAT
ATTCACCGTCATCCTGAGTG

Product: putative cytosine/adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MMTLDDTYFMKQALIEAGKAAERGEVPVGAVVVCKERIIARAHNLTETLNDVTAHAEMQAITAAANVLGGKYLNECTLYV
TVEPCVMCAGAIAWAQTGKLVFGAEDDKRGYQRYAAQALHPKTVVVKGILADECATLMKDFFASKRR

Sequences:

>Translated_147_residues
MMTLDDTYFMKQALIEAGKAAERGEVPVGAVVVCKERIIARAHNLTETLNDVTAHAEMQAITAAANVLGGKYLNECTLYV
TVEPCVMCAGAIAWAQTGKLVFGAEDDKRGYQRYAAQALHPKTVVVKGILADECATLMKDFFASKRR
>Mature_147_residues
MMTLDDTYFMKQALIEAGKAAERGEVPVGAVVVCKERIIARAHNLTETLNDVTAHAEMQAITAAANVLGGKYLNECTLYV
TVEPCVMCAGAIAWAQTGKLVFGAEDDKRGYQRYAAQALHPKTVVVKGILADECATLMKDFFASKRR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=147, Percent_Identity=31.2925170068027, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI145693172, Length=145, Percent_Identity=43.448275862069, Blast_Score=116, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=33.1081081081081, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=39.1752577319588, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17555996, Length=113, Percent_Identity=35.3982300884956, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=154, Percent_Identity=29.8701298701299, Blast_Score=61, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355527, Length=142, Percent_Identity=33.8028169014084, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15971; Mature: 15971

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLDDTYFMKQALIEAGKAAERGEVPVGAVVVCKERIIARAHNLTETLNDVTAHAEMQA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITAAANVLGGKYLNECTLYVTVEPCVMCAGAIAWAQTGKLVFGAEDDKRGYQRYAAQALH
HHHHHHHHCCHHHCCEEEEEEECHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCC
PKTVVVKGILADECATLMKDFFASKRR
CHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMTLDDTYFMKQALIEAGKAAERGEVPVGAVVVCKERIIARAHNLTETLNDVTAHAEMQA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITAAANVLGGKYLNECTLYVTVEPCVMCAGAIAWAQTGKLVFGAEDDKRGYQRYAAQALH
HHHHHHHHCCHHHCCEEEEEEECHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCC
PKTVVVKGILADECATLMKDFFASKRR
CHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]