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The map label for this gene is namA [H]

Identifier: 29347477

GI number: 29347477

Start: 2588329

End: 2589552

Strand: Reverse

Name: namA [H]

Synonym: BT_2067

Alternate gene names: 29347477

Gene position: 2589552-2588329 (Counterclockwise)

Preceding gene: 29347478

Following gene: 29347476

Centisome position: 41.36

GC content: 54.66

Gene sequence:

>1224_bases
ATGGAATCTAAACTTTTCACCCCTGTTACTTTCGGTCCATTGACGCTGCGGAATCGTACGATCCGCTCTGCCGCTTTTGA
AAGCATGTGTCCCGGTAACGCCCCTTCACAAATGCTGCTCGATTACCACCGCTCGGTGGCTGCGGGCGGAGTCGGGATGA
CGACTGTAGCCTATGCAGCCGTGACACAAAGCGGACTTTCCTTCGACCGTCAGTTGTGGCTGCGTCCGGAAATCATTTCC
GGTTTGCGTGAAGTGACCGGAGCTATACACACGGAAGGTGCGGCAGCAGGCATCCAGATAGGGCACTGCGGAAATATGTC
CCATAAAAAGATTTGCGGAACCACTCCCATTTCAGCTTCTACCGGTTTCAATCTCTATTCTCCTACATTCGTGCGTGGCA
TGAAGAGAGAAGAGTTGCCGGAGATGGCCAGAGCCTACGGACGGGCTGTCCACTTGGCACGGGAAGCCGGCTTCGACGCC
GTCGAGGTACACGCCGGACACGGATATCTGATCAGCCAGTTCCTGTCTCCCTACACCAATCACCGGAAAGACGACTACGG
CGGCTTGCTCCAAAACCGGATGCGCTTTATGGAAATGGTGATGAACGAGGTGATGACAGCGGCGGGAAGCGACATGGCAG
TCATTGTAAAAATGAATATGCGCGATGGCTTCAAAGGCGGCATGGAAACCGATGAATCTCTGCAAGTGGCCAAACGCCTG
CTGGCATTGGGCGCGCACGCATTGGTACTGAGCGGAGGATTCGTCAGCAAGGCCCCGATGTACGTCATGCGGGGAGCGAT
GCCGATTCGTTCGATGGCTTACTACATGGACTGCTGGTGGCTGAAATACGGAGTCCGGATGTTTGGAAAGTGGATGATTC
CGACCGTTCCTTTCCGGGAAGCCTATTTCCTGGAGGATGCACTGAAATTTCGGGCGGCACTTCCGGAAGCCCCGTTGATT
TATGTGGGCGGACTGGTGTCCCGCGAAAAGATAGATGAAGTATTGGATGCCGGCTTCGATGCCGTCCAGATGGCACGTGC
GTTGCTCAACGAACCGGAGTTTGTCAACCGGATGAGGCGGGAAGAGCAGGCGCGCTGTAACTGCGGACACAGCAACTACT
GCATCGGGCGGATGTACACAATCGAAATGGCCTGCCACCAACATCTGAAAGAAAAACTGCCTCCCTGCCTGCAACGGGAG
ATTGAAAAACTGGAAAAGCAATGA

Upstream 100 bases:

>100_bases
ACCGTGAAGAATTTGGCTCGGAAGTAGGCGAACGCAAACGTGTATTTCCTTTTATCTATTGATTTGAAATAAATTATCTA
TTGACATAAAATAGCGTACT

Downstream 100 bases:

>100_bases
GTGAAGAGAAATGGGCAATCATCACCGGTGCCGACGGCGGCATGGGAACGGAAATAACCCGTGCCGTAGCCGAAGCCGGT
TACCATATTATTATGGCTTG

Product: putative NADH:flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MESKLFTPVTFGPLTLRNRTIRSAAFESMCPGNAPSQMLLDYHRSVAAGGVGMTTVAYAAVTQSGLSFDRQLWLRPEIIS
GLREVTGAIHTEGAAAGIQIGHCGNMSHKKICGTTPISASTGFNLYSPTFVRGMKREELPEMARAYGRAVHLAREAGFDA
VEVHAGHGYLISQFLSPYTNHRKDDYGGLLQNRMRFMEMVMNEVMTAAGSDMAVIVKMNMRDGFKGGMETDESLQVAKRL
LALGAHALVLSGGFVSKAPMYVMRGAMPIRSMAYYMDCWWLKYGVRMFGKWMIPTVPFREAYFLEDALKFRAALPEAPLI
YVGGLVSREKIDEVLDAGFDAVQMARALLNEPEFVNRMRREEQARCNCGHSNYCIGRMYTIEMACHQHLKEKLPPCLQRE
IEKLEKQ

Sequences:

>Translated_407_residues
MESKLFTPVTFGPLTLRNRTIRSAAFESMCPGNAPSQMLLDYHRSVAAGGVGMTTVAYAAVTQSGLSFDRQLWLRPEIIS
GLREVTGAIHTEGAAAGIQIGHCGNMSHKKICGTTPISASTGFNLYSPTFVRGMKREELPEMARAYGRAVHLAREAGFDA
VEVHAGHGYLISQFLSPYTNHRKDDYGGLLQNRMRFMEMVMNEVMTAAGSDMAVIVKMNMRDGFKGGMETDESLQVAKRL
LALGAHALVLSGGFVSKAPMYVMRGAMPIRSMAYYMDCWWLKYGVRMFGKWMIPTVPFREAYFLEDALKFRAALPEAPLI
YVGGLVSREKIDEVLDAGFDAVQMARALLNEPEFVNRMRREEQARCNCGHSNYCIGRMYTIEMACHQHLKEKLPPCLQRE
IEKLEKQ
>Mature_407_residues
MESKLFTPVTFGPLTLRNRTIRSAAFESMCPGNAPSQMLLDYHRSVAAGGVGMTTVAYAAVTQSGLSFDRQLWLRPEIIS
GLREVTGAIHTEGAAAGIQIGHCGNMSHKKICGTTPISASTGFNLYSPTFVRGMKREELPEMARAYGRAVHLAREAGFDA
VEVHAGHGYLISQFLSPYTNHRKDDYGGLLQNRMRFMEMVMNEVMTAAGSDMAVIVKMNMRDGFKGGMETDESLQVAKRL
LALGAHALVLSGGFVSKAPMYVMRGAMPIRSMAYYMDCWWLKYGVRMFGKWMIPTVPFREAYFLEDALKFRAALPEAPLI
YVGGLVSREKIDEVLDAGFDAVQMARALLNEPEFVNRMRREEQARCNCGHSNYCIGRMYTIEMACHQHLKEKLPPCLQRE
IEKLEKQ

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=395, Percent_Identity=26.8354430379747, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789463, Length=410, Percent_Identity=25.1219512195122, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI72001454, Length=276, Percent_Identity=25.3623188405797, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565138, Length=280, Percent_Identity=25, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559802, Length=282, Percent_Identity=25.886524822695, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564188, Length=278, Percent_Identity=24.4604316546763, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559804, Length=280, Percent_Identity=24.2857142857143, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17566914, Length=318, Percent_Identity=23.8993710691824, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540738, Length=139, Percent_Identity=30.2158273381295, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=227, Percent_Identity=25.9911894273128, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=227, Percent_Identity=22.4669603524229, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 45439; Mature: 45439

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKLFTPVTFGPLTLRNRTIRSAAFESMCPGNAPSQMLLDYHRSVAAGGVGMTTVAYAA
CCCCCCCCEECCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
VTQSGLSFDRQLWLRPEIISGLREVTGAIHTEGAAAGIQIGHCGNMSHKKICGTTPISAS
HHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
TGFNLYSPTFVRGMKREELPEMARAYGRAVHLAREAGFDAVEVHAGHGYLISQFLSPYTN
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
HRKDDYGGLLQNRMRFMEMVMNEVMTAAGSDMAVIVKMNMRDGFKGGMETDESLQVAKRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
LALGAHALVLSGGFVSKAPMYVMRGAMPIRSMAYYMDCWWLKYGVRMFGKWMIPTVPFRE
HHHCCHHHHEECCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AYFLEDALKFRAALPEAPLIYVGGLVSREKIDEVLDAGFDAVQMARALLNEPEFVNRMRR
HHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
EEQARCNCGHSNYCIGRMYTIEMACHQHLKEKLPPCLQREIEKLEKQ
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MESKLFTPVTFGPLTLRNRTIRSAAFESMCPGNAPSQMLLDYHRSVAAGGVGMTTVAYAA
CCCCCCCCEECCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
VTQSGLSFDRQLWLRPEIISGLREVTGAIHTEGAAAGIQIGHCGNMSHKKICGTTPISAS
HHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
TGFNLYSPTFVRGMKREELPEMARAYGRAVHLAREAGFDAVEVHAGHGYLISQFLSPYTN
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
HRKDDYGGLLQNRMRFMEMVMNEVMTAAGSDMAVIVKMNMRDGFKGGMETDESLQVAKRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
LALGAHALVLSGGFVSKAPMYVMRGAMPIRSMAYYMDCWWLKYGVRMFGKWMIPTVPFRE
HHHCCHHHHEECCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AYFLEDALKFRAALPEAPLIYVGGLVSREKIDEVLDAGFDAVQMARALLNEPEFVNRMRR
HHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
EEQARCNCGHSNYCIGRMYTIEMACHQHLKEKLPPCLQREIEKLEKQ
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA