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The map label for this gene is phnXW [H]

Identifier: 29347128

GI number: 29347128

Start: 2115309

End: 2116430

Strand: Reverse

Name: phnXW [H]

Synonym: BT_1718

Alternate gene names: 29347128

Gene position: 2116430-2115309 (Counterclockwise)

Preceding gene: 29347129

Following gene: 29347127

Centisome position: 33.81

GC content: 36.9

Gene sequence:

>1122_bases
ATGAAAATAGAAAGAAAAATATTATTAAATCCTGGGCCTGCCACTACTACTGACAGTGTAAAAATGGCACAAGTTGTTCC
GGATATTTGTCCTCGCGAGAAAGAATTCGCAGGTATGATGAAACAACTTCGGGACGATTTGGTCAGAGTTGCTCATGGGA
ATTTGGAAAAACATACCGCTGTATTATTTTGTGGCTCAGGAACCATCAATATTGATATATGTCTAAATTCTCTTCTTCCT
GAAGACAAAAGGGTGCTTATAGTGAATAATGGGGCATATAGTACCCGTGCTGTAGAAGTGTGTCAATATTATGGTTTGCC
TCATATTAATTTGGAATTTTCCGTTTACGAACGTCCTGATTTATCGGTGGTGGAAAATGTGTTGCAAGAAAATCCTGATA
TAGCTATGGTTTATACTACTCATCACGAGACGGGTACAGGAATTCTGAACCCTATTCGCGAGATGGGCGCTATAGCTCAT
AAATATCAGGCTAAATTTGTCGTCGATACTACTTCTTCTTTGGGCATGATTCCTTTTGATATAGAGAAAGATAATGTGGA
TTTTTGTATGGCATCTGCTCAAAAAGGACTTCAAGCGATGACAGGTCTTTCTTTTATTATAGGCAATGAGGAACAGATTA
AGTTTTCAAAAAAATATCCCAAGCGTTCTTACTATTGTAATCTTTATTTGCAGTATGAGAATTTTGAGAGAACAGGTGAA
ATGCATTTTACTCCACCGGTACAAACTATTTACGCCACTCGTCAGGCATTAAATGAATATTTTGAAGTGGGTGAAGAAGC
TAAGTTTGCCCGTCACAAAAGAGTTTTTGAGGCTATTCATTCAGGTATAAATGAAATTGGTCTTAAAAGTGTAATAAAGC
GTGAATGGCAGTCAGGACTGGTTGTCTCAGTTCAATACCCAGAAGATCCCAACTGGGATTTTGAGAAAATACATGATTAT
TGTTATGAGCGTGGATTTACGATTTATCCAGGTAAGATATCAACTGAGGATACTTTTAGAATCTGTGCTTTAGGAGAGAT
AGAAGTAGATGATATTGAGAACTTCTTTAAAGTACTAAAAGCTGCATTAAATCATTATAACGTCACATTACCGATGTCAT
GA

Upstream 100 bases:

>100_bases
AAAGGTTAAAATAGATTCTCGGGAGAATTTGGGACGTCCCACGACTACTCCTATAGAGAATAAGGAGCATTTTATGGATT
TTTTAAAATAAATATATTCG

Downstream 100 bases:

>100_bases
TTGCAGAAATATTATTGAAGATTCGTCATTTTTATTTTTCCCTTCGTGGTATACACTTCCATCCGGAAAGTGTTATTTCT
GGAGTGCCTATTCGTAGCTT

Product: putative 2-aminoethylphosphonate pyruvate aminotransferase

Products: NA

Alternate protein names: Phosphonoacetaldehyde hydrolase; Phosphonatase; Phosphonoacetaldehyde phosphonohydrolase; 2-aminoethylphosphonate--pyruvate transaminase; 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLP
EDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAH
KYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGE
MHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDY
CYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHYNVTLPMS

Sequences:

>Translated_373_residues
MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLP
EDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAH
KYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGE
MHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDY
CYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHYNVTLPMS
>Mature_373_residues
MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLP
EDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAH
KYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGE
MHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDY
CYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHYNVTLPMS

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=378, Percent_Identity=24.6031746031746, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536281, Length=320, Percent_Identity=24.6875, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321079, Length=300, Percent_Identity=26.3333333333333, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17530823, Length=373, Percent_Identity=24.9329758713137, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR005834
- InterPro:   IPR000418
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR012703
- InterPro:   IPR006323
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5; PF00702 Hydrolase [H]

EC number: =3.11.1.1; =2.6.1.37 [H]

Molecular weight: Translated: 42512; Mature: 42512

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRDDLVRVAHGNLEKHTA
CCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPD
EEEECCCEEEEEEEEHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCC
LSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFD
HHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEE
IEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGE
CCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHEEEHHCCCCCCEEEEEEEEEECCCCCCC
MHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGL
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCE
VVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLK
EEEEECCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
AALNHYNVTLPMS
HHHHHCEEEEECC
>Mature Secondary Structure
MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRDDLVRVAHGNLEKHTA
CCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPD
EEEECCCEEEEEEEEHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCC
LSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFD
HHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEE
IEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGE
CCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHEEEHHCCCCCCEEEEEEEEEECCCCCCC
MHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGL
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCE
VVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLK
EEEEECCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
AALNHYNVTLPMS
HHHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA