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The map label for this gene is pgcA [H]

Identifier: 29346958

GI number: 29346958

Start: 1908723

End: 1910468

Strand: Reverse

Name: pgcA [H]

Synonym: BT_1548

Alternate gene names: 29346958

Gene position: 1910468-1908723 (Counterclockwise)

Preceding gene: 29346959

Following gene: 29346948

Centisome position: 30.52

GC content: 44.73

Gene sequence:

>1746_bases
ATGGAAAATCAGGAACTTATCAAGCAGGTCACTGAGAAAGCCGAAAAATGGCTGACCCCGGCTTATGATGCCGAAACTCA
GGCTGAAGTGAAACGCATGTTGGAGAACGAAGATAAAACCGAATTGATCGAAGCATTCTACAAAGATCTTGAATTTGGAA
CGGGTGGTTTGCGTGGTATCATGGGAGTAGGTAGCAACCGCATGAATATCTATACGGTAGGTGCTGCTACACAGGGCCTT
TCCAACTATCTGAAGAAGAACTTCAAAGATCTGCCTCAGATTTCTGTAGTGGTTGGTCACGACTGTCGTAACAACAGCCG
TCTGTTCGCTGAAACTTCAGCCAACATTTTCTCAGCTAATGGCATCAAAGTATATCTGTTTGATGATATGCGTCCGACTC
CGGAGATGTCTTTCGCAATCCGTCACCTCGGTTGCCAGAGCGGTATTATCCTGACTGCTTCTCACAATCCGAAAGAATAC
AACGGTTACAAAGCATACTGGGATGATGGTGCGCAAGTACTGGCTCCGCACGATGCTGGTATCATTGATGAAGTGAATAA
TATCGCTTCCGCTGCTGATATCAAGTTCAAGGGGAACCCGGATCTGATTCAGATCATCGGTGAAGATATTGACAAGATTT
ACCTCGATATGGTGAAGACAGTTTCTATTGATCCGGAAGCTATCGCCCGTCATAAGGATATGAAGATCGTTTATACTCCG
ATTCACGGTACAGGTATGATGTTGATTCCGCGCGCTTTGAAGATGTGGGGATTCGAAAATGTATTTACTGTTCCCGAACA
GATGATCAAAGACGGTAACTTCCCGACAGTAATATCTCCGAATCCGGAAAATGCCGAAGCGCTTTCTATGGCTGTCAATC
TGGCTAAAGAAATTGATGCCGATCTTGTGATGGCTTCCGATCCGGATGCCGACCGTGTAGGTATCGCCTGCAAGGACGAC
AAGGGAGAATGGGTACTGATCAACGGTAACCAGACTTGTATGATGTATCTTTACTATATTCTGACTCAGTACAAACAATT
GGGTAAGATCAAGGGTAATGAGTTCTGTGTGAAGACTATCGTTACTACCGAACTTATCAAGAAGATTGCTGATAAGAATA
ACATCGAAATGCTCGACTGCTACACCGGATTCAAGTGGATCGCACGTGAAATCCGTCTGCGTGAAGGCAAAAAGAAATAT
ATCGGTGGTGGTGAAGAGAGTTACGGCTTCCTTGCCGAAGACTTCGTACGTGATAAAGATGCCGTATCAGCTTGCTGTCT
GATTGCAGAAGTAGCTGCATGGGCAAAAGATAACGGTAAGTCATTGTACCAGTTGTTGCTGGATATCTACGTAGAATATG
GATTCTCCAAAGAATTCACAGTGAACGTAGTGAAACCGGGCAAGAGCGGTGCTGAAGAAATCAAAGCTATGATGGAAAAC
TTCCGTGCTAATCCTCCGAAAGAACTGGGTGGCTCCAAGGTGATTTTGAGCAAAGACTATAAGACGCTGAAACAGACAGA
TGCAGAAGGCAAGGTGACTGACCTTGATATGCCGGAAACATCTAATGTGCTCCAATACTTCACTGAAGATGGAAGCAAAG
TTTCAGTTCGCCCGTCGGGAACAGAACCGAAGATCAAATTCTATATGGAAGTACAAGGAGAAATGGGTTGTCGCAACTGT
TTCGCTTCTGCTGATGCTGCTGCAATGGAAAAGATTGAAGCAGTGAAGAAGTCATTAGGTATTTGA

Upstream 100 bases:

>100_bases
TAAACTTATTCTTTTACATTTGTGTGCTCAAGACTTGGCATATATTCAAGGATTGACAGAGAATAGAGAAATAATCATTA
ACCAATAAACAATAATCGAA

Downstream 100 bases:

>100_bases
TTCCGTTCTTCTTCTGATATTTCAGAATAGAGAAATAATAAATAACGCCTCCATAGTCTCGAAGATTATGGAGGCGTTTC
TTTTATGTAACCGCCTTTTC

Product: phosphoglucomutase phosphomannomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MENQELIKQVTEKAEKWLTPAYDAETQAEVKRMLENEDKTELIEAFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLKKNFKDLPQISVVVGHDCRNNSRLFAETSANIFSANGIKVYLFDDMRPTPEMSFAIRHLGCQSGIILTASHNPKEY
NGYKAYWDDGAQVLAPHDAGIIDEVNNIASAADIKFKGNPDLIQIIGEDIDKIYLDMVKTVSIDPEAIARHKDMKIVYTP
IHGTGMMLIPRALKMWGFENVFTVPEQMIKDGNFPTVISPNPENAEALSMAVNLAKEIDADLVMASDPDADRVGIACKDD
KGEWVLINGNQTCMMYLYYILTQYKQLGKIKGNEFCVKTIVTTELIKKIADKNNIEMLDCYTGFKWIAREIRLREGKKKY
IGGGEESYGFLAEDFVRDKDAVSACCLIAEVAAWAKDNGKSLYQLLLDIYVEYGFSKEFTVNVVKPGKSGAEEIKAMMEN
FRANPPKELGGSKVILSKDYKTLKQTDAEGKVTDLDMPETSNVLQYFTEDGSKVSVRPSGTEPKIKFYMEVQGEMGCRNC
FASADAAAMEKIEAVKKSLGI

Sequences:

>Translated_581_residues
MENQELIKQVTEKAEKWLTPAYDAETQAEVKRMLENEDKTELIEAFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLKKNFKDLPQISVVVGHDCRNNSRLFAETSANIFSANGIKVYLFDDMRPTPEMSFAIRHLGCQSGIILTASHNPKEY
NGYKAYWDDGAQVLAPHDAGIIDEVNNIASAADIKFKGNPDLIQIIGEDIDKIYLDMVKTVSIDPEAIARHKDMKIVYTP
IHGTGMMLIPRALKMWGFENVFTVPEQMIKDGNFPTVISPNPENAEALSMAVNLAKEIDADLVMASDPDADRVGIACKDD
KGEWVLINGNQTCMMYLYYILTQYKQLGKIKGNEFCVKTIVTTELIKKIADKNNIEMLDCYTGFKWIAREIRLREGKKKY
IGGGEESYGFLAEDFVRDKDAVSACCLIAEVAAWAKDNGKSLYQLLLDIYVEYGFSKEFTVNVVKPGKSGAEEIKAMMEN
FRANPPKELGGSKVILSKDYKTLKQTDAEGKVTDLDMPETSNVLQYFTEDGSKVSVRPSGTEPKIKFYMEVQGEMGCRNC
FASADAAAMEKIEAVKKSLGI
>Mature_581_residues
MENQELIKQVTEKAEKWLTPAYDAETQAEVKRMLENEDKTELIEAFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLKKNFKDLPQISVVVGHDCRNNSRLFAETSANIFSANGIKVYLFDDMRPTPEMSFAIRHLGCQSGIILTASHNPKEY
NGYKAYWDDGAQVLAPHDAGIIDEVNNIASAADIKFKGNPDLIQIIGEDIDKIYLDMVKTVSIDPEAIARHKDMKIVYTP
IHGTGMMLIPRALKMWGFENVFTVPEQMIKDGNFPTVISPNPENAEALSMAVNLAKEIDADLVMASDPDADRVGIACKDD
KGEWVLINGNQTCMMYLYYILTQYKQLGKIKGNEFCVKTIVTTELIKKIADKNNIEMLDCYTGFKWIAREIRLREGKKKY
IGGGEESYGFLAEDFVRDKDAVSACCLIAEVAAWAKDNGKSLYQLLLDIYVEYGFSKEFTVNVVKPGKSGAEEIKAMMEN
FRANPPKELGGSKVILSKDYKTLKQTDAEGKVTDLDMPETSNVLQYFTEDGSKVSVRPSGTEPKIKFYMEVQGEMGCRNC
FASADAAAMEKIEAVKKSLGI

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=571, Percent_Identity=34.5008756567426, Blast_Score=322, Evalue=5e-88,
Organism=Homo sapiens, GI31377548, Length=553, Percent_Identity=32.0072332730561, Blast_Score=281, Evalue=2e-75,
Organism=Escherichia coli, GI1786904, Length=526, Percent_Identity=24.5247148288973, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71993870, Length=565, Percent_Identity=32.3893805309734, Blast_Score=269, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71993878, Length=327, Percent_Identity=34.8623853211009, Blast_Score=184, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6323934, Length=584, Percent_Identity=32.1917808219178, Blast_Score=271, Evalue=3e-73,
Organism=Drosophila melanogaster, GI20129809, Length=560, Percent_Identity=30.8928571428571, Blast_Score=254, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24651977, Length=464, Percent_Identity=32.1120689655172, Blast_Score=233, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24653722, Length=581, Percent_Identity=29.0877796901893, Blast_Score=229, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 64717; Mature: 64717

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQELIKQVTEKAEKWLTPAYDAETQAEVKRMLENEDKTELIEAFYKDLEFGTGGLRGI
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
MGVGSNRMNIYTVGAATQGLSNYLKKNFKDLPQISVVVGHDCRNNSRLFAETSANIFSAN
HCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCEEECC
GIKVYLFDDMRPTPEMSFAIRHLGCQSGIILTASHNPKEYNGYKAYWDDGAQVLAPHDAG
CEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCC
IIDEVNNIASAADIKFKGNPDLIQIIGEDIDKIYLDMVKTVSIDPEAIARHKDMKIVYTP
HHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEE
IHGTGMMLIPRALKMWGFENVFTVPEQMIKDGNFPTVISPNPENAEALSMAVNLAKEIDA
CCCCCHHHHHHHHHHCCCCCHHHCHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
DLVMASDPDADRVGIACKDDKGEWVLINGNQTCMMYLYYILTQYKQLGKIKGNEFCVKTI
CEEEECCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VTTELIKKIADKNNIEMLDCYTGFKWIAREIRLREGKKKYIGGGEESYGFLAEDFVRDKD
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCHH
AVSACCLIAEVAAWAKDNGKSLYQLLLDIYVEYGFSKEFTVNVVKPGKSGAEEIKAMMEN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHH
FRANPPKELGGSKVILSKDYKTLKQTDAEGKVTDLDMPETSNVLQYFTEDGSKVSVRPSG
HCCCCCHHCCCCEEEEECCHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCEEEEECCC
TEPKIKFYMEVQGEMGCRNCFASADAAAMEKIEAVKKSLGI
CCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENQELIKQVTEKAEKWLTPAYDAETQAEVKRMLENEDKTELIEAFYKDLEFGTGGLRGI
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
MGVGSNRMNIYTVGAATQGLSNYLKKNFKDLPQISVVVGHDCRNNSRLFAETSANIFSAN
HCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCEEECC
GIKVYLFDDMRPTPEMSFAIRHLGCQSGIILTASHNPKEYNGYKAYWDDGAQVLAPHDAG
CEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCC
IIDEVNNIASAADIKFKGNPDLIQIIGEDIDKIYLDMVKTVSIDPEAIARHKDMKIVYTP
HHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEE
IHGTGMMLIPRALKMWGFENVFTVPEQMIKDGNFPTVISPNPENAEALSMAVNLAKEIDA
CCCCCHHHHHHHHHHCCCCCHHHCHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
DLVMASDPDADRVGIACKDDKGEWVLINGNQTCMMYLYYILTQYKQLGKIKGNEFCVKTI
CEEEECCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VTTELIKKIADKNNIEMLDCYTGFKWIAREIRLREGKKKYIGGGEESYGFLAEDFVRDKD
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCHH
AVSACCLIAEVAAWAKDNGKSLYQLLLDIYVEYGFSKEFTVNVVKPGKSGAEEIKAMMEN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHH
FRANPPKELGGSKVILSKDYKTLKQTDAEGKVTDLDMPETSNVLQYFTEDGSKVSVRPSG
HCCCCCHHCCCCEEEEECCHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCEEEEECCC
TEPKIKFYMEVQGEMGCRNCFASADAAAMEKIEAVKKSLGI
CCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]