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The map label for this gene is 29346936

Identifier: 29346936

GI number: 29346936

Start: 1880007

End: 1881296

Strand: Reverse

Name: 29346936

Synonym: BT_1526

Alternate gene names: NA

Gene position: 1881296-1880007 (Counterclockwise)

Preceding gene: 29346937

Following gene: 29346935

Centisome position: 30.05

GC content: 46.12

Gene sequence:

>1290_bases
ATGAAACAAGAAATTAAACCCGCTACTGGACGTCTTGGCGTGTTGGTAGTTGGAGTAGGTGGTGCGGTTGCCACCACAAT
GATTGTAGGTACACTAGCCTCTCGCAAGGGACTGGCAAAACCGATAGGATCTATTACACAGTTAGCCACAATGCGCATGG
AAAACAACGAAGAAAAACTCATCAAGGACGTTGTGCCCTTGACTGATTTGAACGACATTGTTTTCGGTGGATGGGATATC
TTCCCGGACAACGCATATGAAGCTGCTATGTATGCCGAGGTTTTGAAAGAAAAAGACCTGAACGGTGTGAAAGATGAACT
GGAAGCTATCAAGCCGATGCCTGCAGCTTTCGATCACAACTGGGCAAAACGTCTGAATGGTACACATATCAAGAAGGCTG
CTACCCGTTGGGAAATGGTAGAACAACTCCGTCAGGACATCCGCGACTTTAAGGCTGCCAATAACTGCGAACGCGTTGTT
GTACTGTGGGCTGCAAGTACCGAAATCTACATTCCGTTATCAGACGAACACATGTCACTCGCTGCTTTGGAGAAAGCAAT
GAAAGATAACAACACAGAAGTTATCTCTCCGAGTATGTGTTATGCATACGCTGCTATCGCAGAAGATGCTCCGTTTGTGA
TGGGTGCTCCTAACTTGTGTGTAGATACTCCGGCCATGTGGGAATTCTCTAAACAGAAGAATGTTCCTATCTCCGGTAAA
GACTTCAAGAGCGGTCAGACACTGATGAAAACCGTATTGGCTCCGATGTTCAAGACTCGTATGCTGGGTGTGAACGGTTG
GTTCTCTACCAACATCCTCGGTAACCGTGACGGTGAAGTGCTGGATGATCCGGACAACTTTAAGACAAAAGAAGTTAGTA
AGCTGTCTGTAATCGACACCATCTTCGAACCGGAAAAATATCCGGATCTCTATGGAGACGTTTACCACAAAGTACGCATC
AACTACTATCCTCCCCGTAAGGACAACAAAGAAGCATGGGATAACATCGACATCTTCGGATGGATGGGCTATCCGATGGA
AATCAAGGTAAACTTCCTTTGCCGTGACTCTATCCTGGCTGCTCCTATTGCACTTGACCTGGTATTGTTCAGTGACTTGG
CTATGCGTGCAGGTATGTGTGGCATCCAGACTTGGTTGTCATTCTTCTGCAAGAGCCCGATGCACGATTTCGAACATCAG
CCGGAACACGACCTGTTCACACAATGGAGAATGGTAAAACAGACATTGCGTAACATGATTGGTGAAAAAGAACCTGATTA
TTTAGCTTAA

Upstream 100 bases:

>100_bases
TCCTGCTAATTGCAATGTTTATATAGCAAACAAAGGTCGCTTTAGTAATTAATTAATCTTATTTTTGCATCAATTTTAGT
TTAATTTTAATAGAATAGAA

Downstream 100 bases:

>100_bases
TTAAATAAGTGGAGAGTTGAAAGTTGAGAGTTGAAAGTTGTTGCAATGTAATTGCAGCATTAGACAACTTTTAACTTTCA
ACTTTTATTTTTGGAGCACA

Product: myo-inositol-1-phosphate synthase

Products: 1D-myo-inositol 3-phosphate

Alternate protein names: Inositol-3-Phosphate Synthase; Secreted Protein; Myo-Inositol Phosphate Synthase; InositoL-3-Phosphate Synthase

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKQEIKPATGRLGVLVVGVGGAVATTMIVGTLASRKGLAKPIGSITQLATMRMENNEEKLIKDVVPLTDLNDIVFGGWDI
FPDNAYEAAMYAEVLKEKDLNGVKDELEAIKPMPAAFDHNWAKRLNGTHIKKAATRWEMVEQLRQDIRDFKAANNCERVV
VLWAASTEIYIPLSDEHMSLAALEKAMKDNNTEVISPSMCYAYAAIAEDAPFVMGAPNLCVDTPAMWEFSKQKNVPISGK
DFKSGQTLMKTVLAPMFKTRMLGVNGWFSTNILGNRDGEVLDDPDNFKTKEVSKLSVIDTIFEPEKYPDLYGDVYHKVRI
NYYPPRKDNKEAWDNIDIFGWMGYPMEIKVNFLCRDSILAAPIALDLVLFSDLAMRAGMCGIQTWLSFFCKSPMHDFEHQ
PEHDLFTQWRMVKQTLRNMIGEKEPDYLA

Sequences:

>Translated_429_residues
MKQEIKPATGRLGVLVVGVGGAVATTMIVGTLASRKGLAKPIGSITQLATMRMENNEEKLIKDVVPLTDLNDIVFGGWDI
FPDNAYEAAMYAEVLKEKDLNGVKDELEAIKPMPAAFDHNWAKRLNGTHIKKAATRWEMVEQLRQDIRDFKAANNCERVV
VLWAASTEIYIPLSDEHMSLAALEKAMKDNNTEVISPSMCYAYAAIAEDAPFVMGAPNLCVDTPAMWEFSKQKNVPISGK
DFKSGQTLMKTVLAPMFKTRMLGVNGWFSTNILGNRDGEVLDDPDNFKTKEVSKLSVIDTIFEPEKYPDLYGDVYHKVRI
NYYPPRKDNKEAWDNIDIFGWMGYPMEIKVNFLCRDSILAAPIALDLVLFSDLAMRAGMCGIQTWLSFFCKSPMHDFEHQ
PEHDLFTQWRMVKQTLRNMIGEKEPDYLA
>Mature_429_residues
MKQEIKPATGRLGVLVVGVGGAVATTMIVGTLASRKGLAKPIGSITQLATMRMENNEEKLIKDVVPLTDLNDIVFGGWDI
FPDNAYEAAMYAEVLKEKDLNGVKDELEAIKPMPAAFDHNWAKRLNGTHIKKAATRWEMVEQLRQDIRDFKAANNCERVV
VLWAASTEIYIPLSDEHMSLAALEKAMKDNNTEVISPSMCYAYAAIAEDAPFVMGAPNLCVDTPAMWEFSKQKNVPISGK
DFKSGQTLMKTVLAPMFKTRMLGVNGWFSTNILGNRDGEVLDDPDNFKTKEVSKLSVIDTIFEPEKYPDLYGDVYHKVRI
NYYPPRKDNKEAWDNIDIFGWMGYPMEIKVNFLCRDSILAAPIALDLVLFSDLAMRAGMCGIQTWLSFFCKSPMHDFEHQ
PEHDLFTQWRMVKQTLRNMIGEKEPDYLA

Specific function: Unknown

COG id: COG1260

COG function: function code I; Myo-inositol-1-phosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705558, Length=451, Percent_Identity=32.1507760532151, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI283135176, Length=409, Percent_Identity=32.0293398533007, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI283135178, Length=341, Percent_Identity=31.9648093841642, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25147617, Length=379, Percent_Identity=30.8707124010554, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6322308, Length=457, Percent_Identity=29.3216630196937, Blast_Score=190, Evalue=4e-49,
Organism=Drosophila melanogaster, GI17137626, Length=459, Percent_Identity=31.3725490196078, Blast_Score=202, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.5.1.4

Molecular weight: Translated: 48398; Mature: 48398

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQEIKPATGRLGVLVVGVGGAVATTMIVGTLASRKGLAKPIGSITQLATMRMENNEEKL
CCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHH
IKDVVPLTDLNDIVFGGWDIFPDNAYEAAMYAEVLKEKDLNGVKDELEAIKPMPAAFDHN
HHHHCCCCCCCHHEECCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCH
WAKRLNGTHIKKAATRWEMVEQLRQDIRDFKAANNCERVVVLWAASTEIYIPLSDEHMSL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEECCCCHHH
AALEKAMKDNNTEVISPSMCYAYAAIAEDAPFVMGAPNLCVDTPAMWEFSKQKNVPISGK
HHHHHHHHCCCCEEECCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCCCCCCC
DFKSGQTLMKTVLAPMFKTRMLGVNGWFSTNILGNRDGEVLDDPDNFKTKEVSKLSVIDT
CCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IFEPEKYPDLYGDVYHKVRINYYPPRKDNKEAWDNIDIFGWMGYPMEIKVNFLCRDSILA
HHCCCCCCCHHHHCEEEEEEEECCCCCCCCHHCCCCEEEEECCCCEEEEEEEEECCHHHH
APIALDLVLFSDLAMRAGMCGIQTWLSFFCKSPMHDFEHQPEHDLFTQWRMVKQTLRNMI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
GEKEPDYLA
CCCCCCCCC
>Mature Secondary Structure
MKQEIKPATGRLGVLVVGVGGAVATTMIVGTLASRKGLAKPIGSITQLATMRMENNEEKL
CCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHH
IKDVVPLTDLNDIVFGGWDIFPDNAYEAAMYAEVLKEKDLNGVKDELEAIKPMPAAFDHN
HHHHCCCCCCCHHEECCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCH
WAKRLNGTHIKKAATRWEMVEQLRQDIRDFKAANNCERVVVLWAASTEIYIPLSDEHMSL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEECCCCHHH
AALEKAMKDNNTEVISPSMCYAYAAIAEDAPFVMGAPNLCVDTPAMWEFSKQKNVPISGK
HHHHHHHHCCCCEEECCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCCCCCCC
DFKSGQTLMKTVLAPMFKTRMLGVNGWFSTNILGNRDGEVLDDPDNFKTKEVSKLSVIDT
CCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IFEPEKYPDLYGDVYHKVRINYYPPRKDNKEAWDNIDIFGWMGYPMEIKVNFLCRDSILA
HHCCCCCCCHHHHCEEEEEEEECCCCCCCCHHCCCCEEEEECCCCEEEEEEEEECCHHHH
APIALDLVLFSDLAMRAGMCGIQTWLSFFCKSPMHDFEHQPEHDLFTQWRMVKQTLRNMI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
GEKEPDYLA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glucose 6-phosphate

Specific reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA