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The map label for this gene is lolC [H]

Identifier: 29346885

GI number: 29346885

Start: 1817172

End: 1818329

Strand: Reverse

Name: lolC [H]

Synonym: BT_1475

Alternate gene names: 29346885

Gene position: 1818329-1817172 (Counterclockwise)

Preceding gene: 29346886

Following gene: 29346884

Centisome position: 29.05

GC content: 45.77

Gene sequence:

>1158_bases
ATGGCTGGTATTGCCATAGGGTTGGCTGTTATGATTATTGCGGTGGCGGTAGTCATAGGGTTTAAAAGTGAGGTAAGGAA
TAAAGTCATCGGGTTCGGGTCGCACATTCAGATAGCGAATCTGGATGCGGTCAATTCTTATGAGACTCATCCGATAGCGG
TGGGGGACAGTATGATGACTGCTCTTTCCGGTTATCCCCAAGTAAGCCATGTGCAACGTTATTCTACCAAGCCGGGGATG
ATAAAAACGGATGATGCTTTTCAGGGAATGGTACTGAAAGGTGTCGGACCGGAGTTTGATCCGAGTTTTATGCAGGAGTA
TCTGGTGGAAGGGGAGATTCCTGCGTTCAGCGATTCGGCTTCGAGTAATCAGGTACTTATCTCCAAGGCGCTGGCTACCA
AAATGAAGCTGAAGCTGGGAGATAAGATATATACCTATTATATTCAGGATAATATCCGTGCCCGGCGCTTGACGATTGCA
GGCATTTATCAGACCAATTTCTCGGAGTATGATAATCTGTTTCTGCTGACTGACCTTTATTTGGTGAACCGTCTGAATGG
CTGGGAACCGGAGCAGGTGAGCGGAGTGGAGCTGCAGGTGCGCGACTATGATAAACTGGAAGATATCACTTACGAGATAG
CCGTTGATACGGATAGCCAGCGTGATAAGTTTGGAGGCGTGTATTATGTACGCAATATAGAGCAACTGAATCCCCAGATA
TTTGAATGGCTCAATCTGCTTGATCTGAATGTATGGGTAATCCTTTTCCTGATGATAGGAGTTGCCGGCTTTACCATGAT
TTCCGGTTTGCTGATTATTATCATAGAACGCACCAATATGATCGGAATACTGAAAGCGCTGGGAGCCGATAATTTTACGA
TTCGCAAGACTTTCCTTTGGTTTGCCGTCTTTCTCATCGGCAAGGGGATGCTTTGGGGCAATGCGATTGGACTGGCATTC
TGTTTTATCCAGTCCCAATTCGGAATATTTAAGCTCGATCCGGAGAATTATTATGTTGATACGGTATCGGTTTCTTTCAA
TGTCTGGTTCTTCCTTTTGATCAATGCAGGTACGTTGCTGGCATCGGTTCTGATGCTGATCGGACCTTCTTACTTGATAA
CGAAGATCAATCCTGCAAGCTCCATGCGGTACGAGTAA

Upstream 100 bases:

>100_bases
ATACTTAAAAGAATTGTCGTTATCTCTTTTTATAGCCCGTCGTATTTATCGCGAGAGCGATGGTGGAAAACAGGTTTCAC
GTCCTGCGGTCCTCATTGCT

Downstream 100 bases:

>100_bases
TCTTCTCTTTTTCTTTTCTTTTTTTGCTGCAAAAATAATTTAGACCGTAGCGTGATGTAGAGTGAATAATATGTCTATAT
TTGCGCCCGATTTACTTAAT

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAGIAIGLAVMIIAVAVVIGFKSEVRNKVIGFGSHIQIANLDAVNSYETHPIAVGDSMMTALSGYPQVSHVQRYSTKPGM
IKTDDAFQGMVLKGVGPEFDPSFMQEYLVEGEIPAFSDSASSNQVLISKALATKMKLKLGDKIYTYYIQDNIRARRLTIA
GIYQTNFSEYDNLFLLTDLYLVNRLNGWEPEQVSGVELQVRDYDKLEDITYEIAVDTDSQRDKFGGVYYVRNIEQLNPQI
FEWLNLLDLNVWVILFLMIGVAGFTMISGLLIIIIERTNMIGILKALGADNFTIRKTFLWFAVFLIGKGMLWGNAIGLAF
CFIQSQFGIFKLDPENYYVDTVSVSFNVWFFLLINAGTLLASVLMLIGPSYLITKINPASSMRYE

Sequences:

>Translated_385_residues
MAGIAIGLAVMIIAVAVVIGFKSEVRNKVIGFGSHIQIANLDAVNSYETHPIAVGDSMMTALSGYPQVSHVQRYSTKPGM
IKTDDAFQGMVLKGVGPEFDPSFMQEYLVEGEIPAFSDSASSNQVLISKALATKMKLKLGDKIYTYYIQDNIRARRLTIA
GIYQTNFSEYDNLFLLTDLYLVNRLNGWEPEQVSGVELQVRDYDKLEDITYEIAVDTDSQRDKFGGVYYVRNIEQLNPQI
FEWLNLLDLNVWVILFLMIGVAGFTMISGLLIIIIERTNMIGILKALGADNFTIRKTFLWFAVFLIGKGMLWGNAIGLAF
CFIQSQFGIFKLDPENYYVDTVSVSFNVWFFLLINAGTLLASVLMLIGPSYLITKINPASSMRYE
>Mature_384_residues
AGIAIGLAVMIIAVAVVIGFKSEVRNKVIGFGSHIQIANLDAVNSYETHPIAVGDSMMTALSGYPQVSHVQRYSTKPGMI
KTDDAFQGMVLKGVGPEFDPSFMQEYLVEGEIPAFSDSASSNQVLISKALATKMKLKLGDKIYTYYIQDNIRARRLTIAG
IYQTNFSEYDNLFLLTDLYLVNRLNGWEPEQVSGVELQVRDYDKLEDITYEIAVDTDSQRDKFGGVYYVRNIEQLNPQIF
EWLNLLDLNVWVILFLMIGVAGFTMISGLLIIIIERTNMIGILKALGADNFTIRKTFLWFAVFLIGKGMLWGNAIGLAFC
FIQSQFGIFKLDPENYYVDTVSVSFNVWFFLLINAGTLLASVLMLIGPSYLITKINPASSMRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=360, Percent_Identity=22.7777777777778, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43128; Mature: 42997

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGIAIGLAVMIIAVAVVIGFKSEVRNKVIGFGSHIQIANLDAVNSYETHPIAVGDSMMT
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEECHHHHH
ALSGYPQVSHVQRYSTKPGMIKTDDAFQGMVLKGVGPEFDPSFMQEYLVEGEIPAFSDSA
HHCCCCCHHHHHHHCCCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCC
SSNQVLISKALATKMKLKLGDKIYTYYIQDNIRARRLTIAGIYQTNFSEYDNLFLLTDLY
CCCEEEHHHHHHHHHHHEECCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCEEEEHHHH
LVNRLNGWEPEQVSGVELQVRDYDKLEDITYEIAVDTDSQRDKFGGVYYVRNIEQLNPQI
HHHHCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCHHCCCEEEEECHHHCCHHH
FEWLNLLDLNVWVILFLMIGVAGFTMISGLLIIIIERTNMIGILKALGADNFTIRKTFLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCEEHHHHHHH
FAVFLIGKGMLWGNAIGLAFCFIQSQFGIFKLDPENYYVDTVSVSFNVWFFLLINAGTLL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEEHHEEEEEEHHHHHHH
ASVLMLIGPSYLITKINPASSMRYE
HHHHHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
AGIAIGLAVMIIAVAVVIGFKSEVRNKVIGFGSHIQIANLDAVNSYETHPIAVGDSMMT
CCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEECHHHHH
ALSGYPQVSHVQRYSTKPGMIKTDDAFQGMVLKGVGPEFDPSFMQEYLVEGEIPAFSDSA
HHCCCCCHHHHHHHCCCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCC
SSNQVLISKALATKMKLKLGDKIYTYYIQDNIRARRLTIAGIYQTNFSEYDNLFLLTDLY
CCCEEEHHHHHHHHHHHEECCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCEEEEHHHH
LVNRLNGWEPEQVSGVELQVRDYDKLEDITYEIAVDTDSQRDKFGGVYYVRNIEQLNPQI
HHHHCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCHHCCCEEEEECHHHCCHHH
FEWLNLLDLNVWVILFLMIGVAGFTMISGLLIIIIERTNMIGILKALGADNFTIRKTFLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCEEHHHHHHH
FAVFLIGKGMLWGNAIGLAFCFIQSQFGIFKLDPENYYVDTVSVSFNVWFFLLINAGTLL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEEHHEEEEEEHHHHHHH
ASVLMLIGPSYLITKINPASSMRYE
HHHHHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]