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The map label for this gene is rtcB [H]

Identifier: 29346865

GI number: 29346865

Start: 1792275

End: 1793672

Strand: Reverse

Name: rtcB [H]

Synonym: BT_1455

Alternate gene names: 29346865

Gene position: 1793672-1792275 (Counterclockwise)

Preceding gene: 29346867

Following gene: 29346864

Centisome position: 28.65

GC content: 48.43

Gene sequence:

>1398_bases
ATGGGAATACGATTAAAAGATTTAAGTAAACTGGGATATCGGGATAATGTAGCCCGTAGTCTGGTAGTAGACATTGTAGG
CAAATATTGCAAACATGACACGAAGGAACAGATTGCAATGACTTTGAGCAATATACTCGAACATCCCGAATCTTATAAAA
ACAATGAAATATGGAGTAAGCTGGCGGAACGCCTGTCGCCTACTGTTCTTGCGAAAGAGTTCGTAGCTTACGACTTACGG
GAAGATCCGTTGATGTATAAAACCTATGGAGGTAAGTTTATCGAGACTCTTGCCAAACAACAGATGAATTTGGCTATGCG
CCTGCCTGTAACGGTCGGCGGAGCGTTGATGCCCGATGCGCACGCCGGTTATGGATTGCCTATCGGTGGGGTACTGGCTA
CTGATAATGCCGTGATACCGTATGCTGTCGGGGTTGATATCGGTTGCCGGATGAGTCTGACGGTATTTGATGCGAAAGCA
GACTTCCTGAAACGATATTCTTATCAGATAAAGGAGGCTTTGAAAGACTTTACACATTTCGGAATGGATGGCGGCCTGGG
CTTTGAACAGGAGCATGAAGTGCTGGATCGGGAAGAATTTCGGTTGACTCCTTTATTAAAGGATTTGCAGGGAAAGGCCG
TGCGGCAACTCGGAAGCTCCGGAGGTGGGAATCACTTTGTGGAGTTCGGCGAAATTGCTTTGCAGGCGGATAATGTGCTG
AATCTTCCGGAGGGGAGTTATGTTGCTTTGCTGTCTCATTCCGGTTCACGTGGCTTGGGTGCTGCTATTGCCAAACATTA
CAGTCTGTTGGCCCGTGAAGTCTGCAAACTTCCTCGGGAGGCGCAGCATTTTGCGTGGCTGAGTCTGGACTCCGAAGAAG
GGCAGGAGTATTGGATGAGTATGAATCTGGCAGGAGACTATGCCCGTGCCTGTCACGAGCGTATTCACTTGAATCTATCT
AAAGCATTGGGACTGAAACCTGTTGCGAATGTCAACAACCATCACAACTTTGCGTGGAAAGAGGAGATAGCTCCGGGACG
TATGGCGATTGTGCATCGCAAAGGGGCAACTCCTGCACAAAAGGGACAGGCGGGTCTGATTCCCGGAAGTATGGCTACGG
CAGGTTATCTGGTTTGTGGCAAAGGGGTGGAAGAATCCTTGTGCTCTGCTTCTCATGGAGCCGGAAGAGCGATGTCCCGG
CAAAAAGCAAAGGAGAGTTTCACTCAGTCGGCTTTGAAAAAGATGCTGTCGCAGGCAGACGTGACATTGATAGGCGGAAG
TATCGAGGAAATACCTCTGGCATATAAAGACATCGACCGCGTGATGTACACACAGGAGACTTTGGTGGAAGTGCAGGGTA
GATTTATGCCTCGCATCGTACGAATGAATAAAGAATAA

Upstream 100 bases:

>100_bases
GGATGTTTTGTATCCGTATCCGAAGCATTGGCATACCGTGTATAACCTTACTTTCCGCTGTTGAGGCGGACGGGGTGTGG
TATGCGAACAGAAAAAAAGT

Downstream 100 bases:

>100_bases
GGCGATGAAGGAGAAAGTCTATTTACAGATAACTTCCGGCAGGGGACCTGCGGAATGTTGCCGGGTGGTGGCATTGGTAC
TCGAAAGAATAGTAAGACAG

Product: protein rtcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MGIRLKDLSKLGYRDNVARSLVVDIVGKYCKHDTKEQIAMTLSNILEHPESYKNNEIWSKLAERLSPTVLAKEFVAYDLR
EDPLMYKTYGGKFIETLAKQQMNLAMRLPVTVGGALMPDAHAGYGLPIGGVLATDNAVIPYAVGVDIGCRMSLTVFDAKA
DFLKRYSYQIKEALKDFTHFGMDGGLGFEQEHEVLDREEFRLTPLLKDLQGKAVRQLGSSGGGNHFVEFGEIALQADNVL
NLPEGSYVALLSHSGSRGLGAAIAKHYSLLAREVCKLPREAQHFAWLSLDSEEGQEYWMSMNLAGDYARACHERIHLNLS
KALGLKPVANVNNHHNFAWKEEIAPGRMAIVHRKGATPAQKGQAGLIPGSMATAGYLVCGKGVEESLCSASHGAGRAMSR
QKAKESFTQSALKKMLSQADVTLIGGSIEEIPLAYKDIDRVMYTQETLVEVQGRFMPRIVRMNKE

Sequences:

>Translated_465_residues
MGIRLKDLSKLGYRDNVARSLVVDIVGKYCKHDTKEQIAMTLSNILEHPESYKNNEIWSKLAERLSPTVLAKEFVAYDLR
EDPLMYKTYGGKFIETLAKQQMNLAMRLPVTVGGALMPDAHAGYGLPIGGVLATDNAVIPYAVGVDIGCRMSLTVFDAKA
DFLKRYSYQIKEALKDFTHFGMDGGLGFEQEHEVLDREEFRLTPLLKDLQGKAVRQLGSSGGGNHFVEFGEIALQADNVL
NLPEGSYVALLSHSGSRGLGAAIAKHYSLLAREVCKLPREAQHFAWLSLDSEEGQEYWMSMNLAGDYARACHERIHLNLS
KALGLKPVANVNNHHNFAWKEEIAPGRMAIVHRKGATPAQKGQAGLIPGSMATAGYLVCGKGVEESLCSASHGAGRAMSR
QKAKESFTQSALKKMLSQADVTLIGGSIEEIPLAYKDIDRVMYTQETLVEVQGRFMPRIVRMNKE
>Mature_464_residues
GIRLKDLSKLGYRDNVARSLVVDIVGKYCKHDTKEQIAMTLSNILEHPESYKNNEIWSKLAERLSPTVLAKEFVAYDLRE
DPLMYKTYGGKFIETLAKQQMNLAMRLPVTVGGALMPDAHAGYGLPIGGVLATDNAVIPYAVGVDIGCRMSLTVFDAKAD
FLKRYSYQIKEALKDFTHFGMDGGLGFEQEHEVLDREEFRLTPLLKDLQGKAVRQLGSSGGGNHFVEFGEIALQADNVLN
LPEGSYVALLSHSGSRGLGAAIAKHYSLLAREVCKLPREAQHFAWLSLDSEEGQEYWMSMNLAGDYARACHERIHLNLSK
ALGLKPVANVNNHHNFAWKEEIAPGRMAIVHRKGATPAQKGQAGLIPGSMATAGYLVCGKGVEESLCSASHGAGRAMSRQ
KAKESFTQSALKKMLSQADVTLIGGSIEEIPLAYKDIDRVMYTQETLVEVQGRFMPRIVRMNKE

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=433, Percent_Identity=28.175519630485, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI2367224, Length=390, Percent_Identity=33.5897435897436, Blast_Score=169, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17506665, Length=433, Percent_Identity=28.8683602771363, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24585217, Length=426, Percent_Identity=26.7605633802817, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 51263; Mature: 51131

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRLKDLSKLGYRDNVARSLVVDIVGKYCKHDTKEQIAMTLSNILEHPESYKNNEIWSK
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
LAERLSPTVLAKEFVAYDLREDPLMYKTYGGKFIETLAKQQMNLAMRLPVTVGGALMPDA
HHHHHCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCEEEECCEEECCCCCCCC
HAGYGLPIGGVLATDNAVIPYAVGVDIGCRMSLTVFDAKADFLKRYSYQIKEALKDFTHF
CCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHC
GMDGGLGFEQEHEVLDREEFRLTPLLKDLQGKAVRQLGSSGGGNHFVEFGEIALQADNVL
CCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHEEEECCCEE
NLPEGSYVALLSHSGSRGLGAAIAKHYSLLAREVCKLPREAQHFAWLSLDSEEGQEYWMS
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCHHHEEE
MNLAGDYARACHERIHLNLSKALGLKPVANVNNHHNFAWKEEIAPGRMAIVHRKGATPAQ
ECCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHH
KGQAGLIPGSMATAGYLVCGKGVEESLCSASHGAGRAMSRQKAKESFTQSALKKMLSQAD
CCCCCCCCCCHHHCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
VTLIGGSIEEIPLAYKDIDRVMYTQETLVEVQGRFMPRIVRMNKE
EEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GIRLKDLSKLGYRDNVARSLVVDIVGKYCKHDTKEQIAMTLSNILEHPESYKNNEIWSK
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
LAERLSPTVLAKEFVAYDLREDPLMYKTYGGKFIETLAKQQMNLAMRLPVTVGGALMPDA
HHHHHCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCEEEECCEEECCCCCCCC
HAGYGLPIGGVLATDNAVIPYAVGVDIGCRMSLTVFDAKADFLKRYSYQIKEALKDFTHF
CCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHC
GMDGGLGFEQEHEVLDREEFRLTPLLKDLQGKAVRQLGSSGGGNHFVEFGEIALQADNVL
CCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHEEEECCCEE
NLPEGSYVALLSHSGSRGLGAAIAKHYSLLAREVCKLPREAQHFAWLSLDSEEGQEYWMS
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCHHHEEE
MNLAGDYARACHERIHLNLSKALGLKPVANVNNHHNFAWKEEIAPGRMAIVHRKGATPAQ
ECCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHH
KGQAGLIPGSMATAGYLVCGKGVEESLCSASHGAGRAMSRQKAKESFTQSALKKMLSQAD
CCCCCCCCCCHHHCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
VTLIGGSIEEIPLAYKDIDRVMYTQETLVEVQGRFMPRIVRMNKE
EEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9738023 [H]