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The map label for this gene is prfH [H]

Identifier: 29346864

GI number: 29346864

Start: 1791650

End: 1792270

Strand: Reverse

Name: prfH [H]

Synonym: BT_1454

Alternate gene names: 29346864

Gene position: 1792270-1791650 (Counterclockwise)

Preceding gene: 29346865

Following gene: 29346860

Centisome position: 28.63

GC content: 52.66

Gene sequence:

>621_bases
ATGAAGGAGAAAGTCTATTTACAGATAACTTCCGGCAGGGGACCTGCGGAATGTTGCCGGGTGGTGGCATTGGTACTCGA
AAGAATAGTAAGACAGGCGCAGGCAAGCGGACTGAAAATGGAAATGATAGAACGTGAAGTGGGACCGGTCAACCGGACAC
TGCTTTCGGCTACCATTGCTCTTCAAGGCGCAGCGAGCGGAGAACTGGCGGATGAATGGGAGGGAACGGTGCAATGGATT
GCCCAAAGCCCGTATCGCATTTATCACAAGCGGAAAAACTGGTTTGTCGGTGTGCATTCGTTTGTGTTGTCGGAGAGTCA
GGAGGCTACAGAAAGAGATTTCCGCTATGAAACCTTACGGGCTTCCGGTCCGGGCGGGCAGCATGTCAACAAGACAGAGT
CCGCGGTCCGTGCCGTTCACATCCCGTCCGGGATGAGTGTGGTAGCTTCCGACCAACGTTCACAATGGCAGAACAAGAAG
CTGGCAACGGAACGCCTGTTGGTGAAACTTTCGTCATGGACGATGGAACAGGCGATGATTCAGGCGCAGGAAAACTGGAG
TAATCATAATCATCTTCAACGGGGGAATCCCGTGAAGGTGATTCGGGAACCGCTGATTTAG

Upstream 100 bases:

>100_bases
TATAAAGACATCGACCGCGTGATGTACACACAGGAGACTTTGGTGGAAGTGCAGGGTAGATTTATGCCTCGCATCGTACG
AATGAATAAAGAATAAGGCG

Downstream 100 bases:

>100_bases
CTGTGAGTAATAAAAAATATATAAAGTGACTAAAAAGTCGGTTCTATCTCCCATTCCCCTCCCTTCGGGAAGGAAGGGTG
GCTGAAAGTCGGGGTGGTAG

Product: peptide chain release factor-like protein

Products: NA

Alternate protein names: RF-H [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKEKVYLQITSGRGPAECCRVVALVLERIVRQAQASGLKMEMIEREVGPVNRTLLSATIALQGAASGELADEWEGTVQWI
AQSPYRIYHKRKNWFVGVHSFVLSESQEATERDFRYETLRASGPGGQHVNKTESAVRAVHIPSGMSVVASDQRSQWQNKK
LATERLLVKLSSWTMEQAMIQAQENWSNHNHLQRGNPVKVIREPLI

Sequences:

>Translated_206_residues
MKEKVYLQITSGRGPAECCRVVALVLERIVRQAQASGLKMEMIEREVGPVNRTLLSATIALQGAASGELADEWEGTVQWI
AQSPYRIYHKRKNWFVGVHSFVLSESQEATERDFRYETLRASGPGGQHVNKTESAVRAVHIPSGMSVVASDQRSQWQNKK
LATERLLVKLSSWTMEQAMIQAQENWSNHNHLQRGNPVKVIREPLI
>Mature_206_residues
MKEKVYLQITSGRGPAECCRVVALVLERIVRQAQASGLKMEMIEREVGPVNRTLLSATIALQGAASGELADEWEGTVQWI
AQSPYRIYHKRKNWFVGVHSFVLSESQEATERDFRYETLRASGPGGQHVNKTESAVRAVHIPSGMSVVASDQRSQWQNKK
LATERLLVKLSSWTMEQAMIQAQENWSNHNHLQRGNPVKVIREPLI

Specific function: Could be involved in translational termination [H]

COG id: COG1186

COG function: function code J; Protein chain release factor B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic/mitochondrial release factor family [H]

Homologues:

Organism=Homo sapiens, GI34577120, Length=72, Percent_Identity=48.6111111111111, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI166795303, Length=72, Percent_Identity=48.6111111111111, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI2367172, Length=203, Percent_Identity=31.0344827586207, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787462, Length=84, Percent_Identity=41.6666666666667, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321295, Length=72, Percent_Identity=50, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19921226, Length=86, Percent_Identity=46.5116279069767, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000352
- InterPro:   IPR017509 [H]

Pfam domain/function: PF00472 RF-1 [H]

EC number: NA

Molecular weight: Translated: 23248; Mature: 23248

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00745 RF_PROK_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKVYLQITSGRGPAECCRVVALVLERIVRQAQASGLKMEMIEREVGPVNRTLLSATIA
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
LQGAASGELADEWEGTVQWIAQSPYRIYHKRKNWFVGVHSFVLSESQEATERDFRYETLR
HCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEHHHHHHHCCCHHHHHHHHHHHHEE
ASGPGGQHVNKTESAVRAVHIPSGMSVVASDQRSQWQNKKLATERLLVKLSSWTMEQAMI
CCCCCCCCCCHHHHHHEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAQENWSNHNHLQRGNPVKVIREPLI
HHHHCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MKEKVYLQITSGRGPAECCRVVALVLERIVRQAQASGLKMEMIEREVGPVNRTLLSATIA
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
LQGAASGELADEWEGTVQWIAQSPYRIYHKRKNWFVGVHSFVLSESQEATERDFRYETLR
HCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEHHHHHHHCCCHHHHHHHHHHHHEE
ASGPGGQHVNKTESAVRAVHIPSGMSVVASDQRSQWQNKKLATERLLVKLSSWTMEQAMI
CCCCCCCCCCHHHHHHEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAQENWSNHNHLQRGNPVKVIREPLI
HHHHCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1695895; 9278503; 1408743 [H]