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The map label for this gene is luxQ [H]

Identifier: 29345946

GI number: 29345946

Start: 659481

End: 660041

Strand: Reverse

Name: luxQ [H]

Synonym: BT_0536

Alternate gene names: 29345946

Gene position: 660041-659481 (Counterclockwise)

Preceding gene: 29345947

Following gene: 29345944

Centisome position: 10.54

GC content: 43.85

Gene sequence:

>561_bases
ATGAAGATAGTGTCCAGTAACAATGAGTTGTTACTGCAATTGATAGATGATATTCTCGATCTTTCCAAAATCGAAGCCGG
AACGATGGAATTTAGCCTCGCCCCTACCGATATCAATGATCTGATGGAAGGTATTTGCAGGCAAATGCAAGAGAAAAACA
CTTCTCCCGACGTGGCGATCACCTTCACGGAGAAAGCGGAAGAATGTATTCTCAACACAGACCGCGTACGTCTTTCGCAA
GTAATCATCAACTTCACAAACAATGCGATGAAGTTCACTCCGAAAGGTTCCATCCAAATGGGATATCGGATTGACGAAGC
AAAAGATGAAATCTACTTCTATGTAAAAGACACGGGCATTGGGATTCCGGAGGATAAAATAAACGAGGTATTCGAACGTT
TCGTCAAGCTGAATACATTCGCAAAAGGTACGGGACTCGGTCTGGCTATCTGCCGGGTGATCGTAGAGCGCTTAGGCGGC
ACTATCGGAGCAGATTCTAAAGAAGGAGAAGGTTCGTGCTTTTGGCTCAGACTTCCGATAACCCAAAAATCAAATAATTA
A

Upstream 100 bases:

>100_bases
TTGCCAACATGAGTCACGAGATACGTACTCCGTTGAATGCGATTATTGGATTCTCTGACATGATTTGCCAACGGGTGAAG
AGGAAGAGAAACAGGAATAC

Downstream 100 bases:

>100_bases
CTGTAAATGGCTGTACACACTAATTCATACTTGTACAGTTTTACTCCTTTCTGTTTAGGAATGAACTAAACAGTAGTACA
CAATAGTAACTCCATTCTCC

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKIVSSNNELLLQLIDDILDLSKIEAGTMEFSLAPTDINDLMEGICRQMQEKNTSPDVAITFTEKAEECILNTDRVRLSQ
VIINFTNNAMKFTPKGSIQMGYRIDEAKDEIYFYVKDTGIGIPEDKINEVFERFVKLNTFAKGTGLGLAICRVIVERLGG
TIGADSKEGEGSCFWLRLPITQKSNN

Sequences:

>Translated_186_residues
MKIVSSNNELLLQLIDDILDLSKIEAGTMEFSLAPTDINDLMEGICRQMQEKNTSPDVAITFTEKAEECILNTDRVRLSQ
VIINFTNNAMKFTPKGSIQMGYRIDEAKDEIYFYVKDTGIGIPEDKINEVFERFVKLNTFAKGTGLGLAICRVIVERLGG
TIGADSKEGEGSCFWLRLPITQKSNN
>Mature_186_residues
MKIVSSNNELLLQLIDDILDLSKIEAGTMEFSLAPTDINDLMEGICRQMQEKNTSPDVAITFTEKAEECILNTDRVRLSQ
VIINFTNNAMKFTPKGSIQMGYRIDEAKDEIYFYVKDTGIGIPEDKINEVFERFVKLNTFAKGTGLGLAICRVIVERLGG
TIGADSKEGEGSCFWLRLPITQKSNN

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=182, Percent_Identity=35.1648351648352, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87081816, Length=183, Percent_Identity=34.9726775956284, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994928, Length=187, Percent_Identity=31.0160427807487, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=190, Percent_Identity=31.0526315789474, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=186, Percent_Identity=26.3440860215054, Blast_Score=85, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=179, Percent_Identity=29.0502793296089, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1786912, Length=169, Percent_Identity=28.4023668639053, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=175, Percent_Identity=29.1428571428571, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 20794; Mature: 20794

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVSSNNELLLQLIDDILDLSKIEAGTMEFSLAPTDINDLMEGICRQMQEKNTSPDVAI
CEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEE
TFTEKAEECILNTDRVRLSQVIINFTNNAMKFTPKGSIQMGYRIDEAKDEIYFYVKDTGI
EECCCHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCEEECEEECCCCCEEEEEEEECCC
GIPEDKINEVFERFVKLNTFAKGTGLGLAICRVIVERLGGTIGADSKEGEGSCFWLRLPI
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
TQKSNN
CCCCCC
>Mature Secondary Structure
MKIVSSNNELLLQLIDDILDLSKIEAGTMEFSLAPTDINDLMEGICRQMQEKNTSPDVAI
CEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEE
TFTEKAEECILNTDRVRLSQVIINFTNNAMKFTPKGSIQMGYRIDEAKDEIYFYVKDTGI
EECCCHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCEEECEEECCCCCEEEEEEEECCC
GIPEDKINEVFERFVKLNTFAKGTGLGLAICRVIVERLGGTIGADSKEGEGSCFWLRLPI
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEC
TQKSNN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA