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The map label for this gene is nagC [H]

Identifier: 29345843

GI number: 29345843

Start: 520419

End: 521627

Strand: Reverse

Name: nagC [H]

Synonym: BT_0433

Alternate gene names: 29345843

Gene position: 521627-520419 (Counterclockwise)

Preceding gene: 29345856

Following gene: 29345842

Centisome position: 8.33

GC content: 41.03

Gene sequence:

>1209_bases
ATGAACCAACAATTCTTGAAAGAAATAGAAATGGGCTCTAAAAATGCCCTCGTTAAAAAGAGGATCATTACACATTATAT
ATATAATGGTAGTTCCACTATTCCCGATCTTTCAAAAGAACTAGATCTAAGCGTGCCCACAGTCACCAAGTTTATCGGTG
AAATGTGTGAGGACGGATATATCAATGATTACGGAAAACTGGAAACCAGCGGTGGACGCCACCCGAATCTCTATGGATTG
AATCCGGAATCCGGTTATTTTATAGGTGTAGACATCAAAAGATTTGCAGTCAATATCGGACTGATCAATTTTAAAGGTGA
TATGGTAGAGTTAAAAATGAATATCCCCTATAAATTTGAGAATTCGATAGAAGGGATGAACGAGTTGTGCAAACTCATTC
TCAACTTCATCAAAAAACTTCCTATCAATAAGGAGAAGATTTTAAATATCAATGTAAATGTATCGGGATGGGTAAATCCG
GAATCCGGATATAGTTTCAGCCAGTTCAATTTTGAGGAACGCCCGTTGGCGGATGTCCTGTCGGAAAAGCTGGGTCATAA
AGTAACCATTGACAACGACACCCGTGCCATGACTTACGGAGAATATATGCAAGGGTGTGTAAAAGGAGAAAAAGATATTA
TTTTCGTCAACGTCAGCTGGGGAGTCGGCATCGGAATTATTATCGACGGCAAAGTCTACACAGGAAAATCCGGTTTCTCG
GGAGAGTTCGGTCACGTCAATGCATACGACAATGAAATCATCTGCCATTGCGGCAAAAAAGGGTGTCTGGAAACAGAAGC
ATCCGGCTCTGCCCTTCATCGCATTCTTTTGGAGCGTATTAAAAGCGGAGAAAGCTCTATTCTTTCCACCCGAATATCCG
GTGAAGAAGACCCCATCACGCTTGACGAAATCATCACAGCCGTCAACAAGGAAGATCTGCTTTGTATTGAAATTGTTGAA
GAAATAGGGCAAAAGCTGGGAAAACAAATTGCAGGATTAATCAATATCTTCAATCCGGAACTGGTCATTATAGGCGGAAC
TTTATCTTTAACGGGAGATTATATCACCCAACCTATCAAAACAGCGGTACGTAAGTATTCACTCAATCTGGTCAACAAAG
ACTCTGCCATCATTACATCCAAATTGAAGGATAAAGCAGGTATTGTAGGCGCGTGTATGCTGGCACGCAGCAGAATGTTC
GAAAGTTAA

Upstream 100 bases:

>100_bases
AGCATCATCTCAGATTCAATTCTAATTTTTTCGTCAAGAACCTTATTAGTTAATAAAAAAATTAATTATCTTTGTAGATA
TTACAAAATATAAGAGACGT

Downstream 100 bases:

>100_bases
ACTACCGTTACTTTATGCAAAGAGTTATGGTAAAGGAAGATTTTAAATTAAAGCTCAAAAAATATTCAGAATCCTTTTGT
TTTCTCAAATAAAGCTGTAA

Product: putative xylose repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNQQFLKEIEMGSKNALVKKRIITHYIYNGSSTIPDLSKELDLSVPTVTKFIGEMCEDGYINDYGKLETSGGRHPNLYGL
NPESGYFIGVDIKRFAVNIGLINFKGDMVELKMNIPYKFENSIEGMNELCKLILNFIKKLPINKEKILNINVNVSGWVNP
ESGYSFSQFNFEERPLADVLSEKLGHKVTIDNDTRAMTYGEYMQGCVKGEKDIIFVNVSWGVGIGIIIDGKVYTGKSGFS
GEFGHVNAYDNEIICHCGKKGCLETEASGSALHRILLERIKSGESSILSTRISGEEDPITLDEIITAVNKEDLLCIEIVE
EIGQKLGKQIAGLINIFNPELVIIGGTLSLTGDYITQPIKTAVRKYSLNLVNKDSAIITSKLKDKAGIVGACMLARSRMF
ES

Sequences:

>Translated_402_residues
MNQQFLKEIEMGSKNALVKKRIITHYIYNGSSTIPDLSKELDLSVPTVTKFIGEMCEDGYINDYGKLETSGGRHPNLYGL
NPESGYFIGVDIKRFAVNIGLINFKGDMVELKMNIPYKFENSIEGMNELCKLILNFIKKLPINKEKILNINVNVSGWVNP
ESGYSFSQFNFEERPLADVLSEKLGHKVTIDNDTRAMTYGEYMQGCVKGEKDIIFVNVSWGVGIGIIIDGKVYTGKSGFS
GEFGHVNAYDNEIICHCGKKGCLETEASGSALHRILLERIKSGESSILSTRISGEEDPITLDEIITAVNKEDLLCIEIVE
EIGQKLGKQIAGLINIFNPELVIIGGTLSLTGDYITQPIKTAVRKYSLNLVNKDSAIITSKLKDKAGIVGACMLARSRMF
ES
>Mature_402_residues
MNQQFLKEIEMGSKNALVKKRIITHYIYNGSSTIPDLSKELDLSVPTVTKFIGEMCEDGYINDYGKLETSGGRHPNLYGL
NPESGYFIGVDIKRFAVNIGLINFKGDMVELKMNIPYKFENSIEGMNELCKLILNFIKKLPINKEKILNINVNVSGWVNP
ESGYSFSQFNFEERPLADVLSEKLGHKVTIDNDTRAMTYGEYMQGCVKGEKDIIFVNVSWGVGIGIIIDGKVYTGKSGFS
GEFGHVNAYDNEIICHCGKKGCLETEASGSALHRILLERIKSGESSILSTRISGEEDPITLDEIITAVNKEDLLCIEIVE
EIGQKLGKQIAGLINIFNPELVIIGGTLSLTGDYITQPIKTAVRKYSLNLVNKDSAIITSKLKDKAGIVGACMLARSRMF
ES

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=286, Percent_Identity=23.7762237762238, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI298566325, Length=286, Percent_Identity=23.7762237762238, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI298566315, Length=286, Percent_Identity=23.7762237762238, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI4885285, Length=286, Percent_Identity=23.7762237762238, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786891, Length=391, Percent_Identity=27.1099744245524, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787878, Length=366, Percent_Identity=25.4098360655738, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082127, Length=347, Percent_Identity=23.0547550432277, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87081733, Length=257, Percent_Identity=23.7354085603113, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787363, Length=320, Percent_Identity=23.125, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44479; Mature: 44479

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQFLKEIEMGSKNALVKKRIITHYIYNGSSTIPDLSKELDLSVPTVTKFIGEMCEDGY
CCHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCC
INDYGKLETSGGRHPNLYGLNPESGYFIGVDIKRFAVNIGLINFKGDMVELKMNIPYKFE
CCCCCCEECCCCCCCCEEECCCCCCEEEEEEHEEEEEEEEEEEECCCEEEEEECCCEEEC
NSIEGMNELCKLILNFIKKLPINKEKILNINVNVSGWVNPESGYSFSQFNFEERPLADVL
HHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHH
SEKLGHKVTIDNDTRAMTYGEYMQGCVKGEKDIIFVNVSWGVGIGIIIDGKVYTGKSGFS
HHHHCCEEEECCCCCEEEHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCEEEECCCCCC
GEFGHVNAYDNEIICHCGKKGCLETEASGSALHRILLERIKSGESSILSTRISGEEDPIT
CCCCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEEECCCCCCCEE
LDEIITAVNKEDLLCIEIVEEIGQKLGKQIAGLINIFNPELVIIGGTLSLTGDYITQPIK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEEEECCHHHHHHHH
TAVRKYSLNLVNKDSAIITSKLKDKAGIVGACMLARSRMFES
HHHHHHHCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQQFLKEIEMGSKNALVKKRIITHYIYNGSSTIPDLSKELDLSVPTVTKFIGEMCEDGY
CCHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCC
INDYGKLETSGGRHPNLYGLNPESGYFIGVDIKRFAVNIGLINFKGDMVELKMNIPYKFE
CCCCCCEECCCCCCCCEEECCCCCCEEEEEEHEEEEEEEEEEEECCCEEEEEECCCEEEC
NSIEGMNELCKLILNFIKKLPINKEKILNINVNVSGWVNPESGYSFSQFNFEERPLADVL
HHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHH
SEKLGHKVTIDNDTRAMTYGEYMQGCVKGEKDIIFVNVSWGVGIGIIIDGKVYTGKSGFS
HHHHCCEEEECCCCCEEEHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCEEEECCCCCC
GEFGHVNAYDNEIICHCGKKGCLETEASGSALHRILLERIKSGESSILSTRISGEEDPIT
CCCCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEEECCCCCCCEE
LDEIITAVNKEDLLCIEIVEEIGQKLGKQIAGLINIFNPELVIIGGTLSLTGDYITQPIK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEEEECCHHHHHHHH
TAVRKYSLNLVNKDSAIITSKLKDKAGIVGACMLARSRMFES
HHHHHHHCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]