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The map label for this gene is plsC [H]

Identifier: 29345653

GI number: 29345653

Start: 267194

End: 268021

Strand: Reverse

Name: plsC [H]

Synonym: BT_0243

Alternate gene names: 29345653

Gene position: 268021-267194 (Counterclockwise)

Preceding gene: 29345656

Following gene: 29345648

Centisome position: 4.28

GC content: 40.1

Gene sequence:

>828_bases
ATGTTGTATCCTACTGCTTTTTTTACCAATAATCATGTATCTTTGCATATATATAAAAATAAACTCCCCATGAAGATACT
ATATTATATTTATCAAATTTGTATTGCTTTACCTATCCTATTGGTATTGACTATTCTTACAGCGATTGTCACCATTGTAG
GCTCTTTACTAGGAGGAGCTCATTTCTGGGGATACTATCCGGGCAAAATATGGTCACAACTCATCTGTCTTTTTCTGTTG
ATTCCTGTAAAGATTCACGGTCGTGAAAAATTACACGGGAAGACCTCTTATATCTTTGTGCCGAATCATCAGGGATCCTT
CGATATTTTTCTTATTTATGGATTCATCGGAAGAAATTTCAAGTGGATGATGAAAAAAAGCCTGCGTAAGATACCATTTG
TAGGAAAAGCATGTGAAAGTGCAGGACACATTTTTGTAGACCGGTCCGGTCCCAAAAAAGTACTGGAGACCATTCGGCAA
GCAAAAGATTCGCTGAAAGACGGGGTATCCTTAGTCGTTTTTCCCGAAGGAGCACGTACTTTCACCGGACACATGGGATA
TTTCAAAAAAGGGGCGTTTCAATTGGCAGATGACTTGCAGCTGGCAGTTGTTCCCGTTACAATCGACGGTTCTTTTGAAA
TCCTGCCACGTACAGGCAAATGGATACATCGCCATCGCATGATTCTGACCATTCATGACCCTATTCCTCCTAAAGGAAAA
GGTATGGAAAACATAAAAGCTACTATGGCAGAGGCTTATGCTGCTGTTGAGAGTGCACTTCCTGAAAAGCATAAAGGAAT
GATCACAAACGAAGATCAGGATCGGTAA

Upstream 100 bases:

>100_bases
AAAAATGTCTGTCCTAAATGCCAATCGGCAGTATGTAGTATACGTATCATATCATTATCTGTCTATAACAGAAGACAAAA
ATAACATAATCGCAAAGATT

Downstream 100 bases:

>100_bases
GAAACGAAATGCGGGGATACTCACGCACCCCCGCATACCTAACCAGTCTTTATGCATTAATCTATTAAATCAAAAAGTCT
ATATATTATGTAGAAATCTT

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLYPTAFFTNNHVSLHIYKNKLPMKILYYIYQICIALPILLVLTILTAIVTIVGSLLGGAHFWGYYPGKIWSQLICLFLL
IPVKIHGREKLHGKTSYIFVPNHQGSFDIFLIYGFIGRNFKWMMKKSLRKIPFVGKACESAGHIFVDRSGPKKVLETIRQ
AKDSLKDGVSLVVFPEGARTFTGHMGYFKKGAFQLADDLQLAVVPVTIDGSFEILPRTGKWIHRHRMILTIHDPIPPKGK
GMENIKATMAEAYAAVESALPEKHKGMITNEDQDR

Sequences:

>Translated_275_residues
MLYPTAFFTNNHVSLHIYKNKLPMKILYYIYQICIALPILLVLTILTAIVTIVGSLLGGAHFWGYYPGKIWSQLICLFLL
IPVKIHGREKLHGKTSYIFVPNHQGSFDIFLIYGFIGRNFKWMMKKSLRKIPFVGKACESAGHIFVDRSGPKKVLETIRQ
AKDSLKDGVSLVVFPEGARTFTGHMGYFKKGAFQLADDLQLAVVPVTIDGSFEILPRTGKWIHRHRMILTIHDPIPPKGK
GMENIKATMAEAYAAVESALPEKHKGMITNEDQDR
>Mature_275_residues
MLYPTAFFTNNHVSLHIYKNKLPMKILYYIYQICIALPILLVLTILTAIVTIVGSLLGGAHFWGYYPGKIWSQLICLFLL
IPVKIHGREKLHGKTSYIFVPNHQGSFDIFLIYGFIGRNFKWMMKKSLRKIPFVGKACESAGHIFVDRSGPKKVLETIRQ
AKDSLKDGVSLVVFPEGARTFTGHMGYFKKGAFQLADDLQLAVVPVTIDGSFEILPRTGKWIHRHRMILTIHDPIPPKGK
GMENIKATMAEAYAAVESALPEKHKGMITNEDQDR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=168, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI15100175, Length=168, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789395, Length=207, Percent_Identity=24.6376811594203, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=202, Percent_Identity=25.7425742574257, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=215, Percent_Identity=31.1627906976744, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24641614, Length=206, Percent_Identity=28.1553398058252, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24641612, Length=206, Percent_Identity=28.1553398058252, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 31072; Mature: 31072

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPTAFFTNNHVSLHIYKNKLPMKILYYIYQICIALPILLVLTILTAIVTIVGSLLGGA
CCCCEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
HFWGYYPGKIWSQLICLFLLIPVKIHGREKLHGKTSYIFVPNHQGSFDIFLIYGFIGRNF
HHCCCCCHHHHHHHHHHHHHHHHEECCCHHCCCCEEEEEEECCCCCEEEEEEEEHHCCCH
KWMMKKSLRKIPFVGKACESAGHIFVDRSGPKKVLETIRQAKDSLKDGVSLVVFPEGART
HHHHHHHHHHCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCE
FTGHMGYFKKGAFQLADDLQLAVVPVTIDGSFEILPRTGKWIHRHRMILTIHDPIPPKGK
EECCCCHHHCCHHHHCCCCEEEEEEEEECCCEEEECCCCHHHHHCEEEEEEECCCCCCCC
GMENIKATMAEAYAAVESALPEKHKGMITNEDQDR
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MLYPTAFFTNNHVSLHIYKNKLPMKILYYIYQICIALPILLVLTILTAIVTIVGSLLGGA
CCCCEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
HFWGYYPGKIWSQLICLFLLIPVKIHGREKLHGKTSYIFVPNHQGSFDIFLIYGFIGRNF
HHCCCCCHHHHHHHHHHHHHHHHEECCCHHCCCCEEEEEEECCCCCEEEEEEEEHHCCCH
KWMMKKSLRKIPFVGKACESAGHIFVDRSGPKKVLETIRQAKDSLKDGVSLVVFPEGART
HHHHHHHHHHCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCE
FTGHMGYFKKGAFQLADDLQLAVVPVTIDGSFEILPRTGKWIHRHRMILTIHDPIPPKGK
EECCCCHHHCCHHHHCCCCEEEEEEEEECCCEEEECCCCHHHHHCEEEEEEECCCCCCCC
GMENIKATMAEAYAAVESALPEKHKGMITNEDQDR
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]