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The map label for this gene is udk [H]

Identifier: 29345594

GI number: 29345594

Start: 194157

End: 194774

Strand: Reverse

Name: udk [H]

Synonym: BT_0184

Alternate gene names: 29345594

Gene position: 194774-194157 (Counterclockwise)

Preceding gene: 29345597

Following gene: 29345593

Centisome position: 3.11

GC content: 44.82

Gene sequence:

>618_bases
ATGTTAATAATAGGAATAGCAGGTGGAACGGGCTCCGGAAAAACCACCGTCGTACGAAAAATGATAGAAAGCCTCCCCGT
TGGAGAAGTAGTACTATTACCTCAGGATTCATACTACAAAGACAGTAGTCACGTGCCGGTTGAAGAACGTCAGAATATCA
ACTTTGACCATCCGGATGCTTTTGAATGGAGCTTGCTTTCCAAACATGTGATGATGCTGAAAGAAGGAAAAAGCATCGAG
CAGCCGACCTATTCTTATCTGACTTGTACCCGCCAACCGGAAACCATCCACATCGAGCCTCGTGAAGTCGTCATTATTGA
AGGTATCCTTGCCTTGTGCGACAAGAAGCTACGCAATATGATGGATCTAAAGATATTTGTAGATGCCGATCCCGATGAAC
GCCTGATACGTGTCATCCAAAGGGATGTCATCGAAAGAGGACGGACAGCGGAAGCTGTCATGGAACGCTATACCCGTGTT
CTGAAACCGATGCACCTGCAATTCATAGAACCCTGCAAACGCTATGCGGACCTTATCGTTCCAGAAGGCGGCAGCAATGC
AGTAGCTATCGATATATTAACAATGTATATCAAGAAACATTTGAAAAATGAAGAATGA

Upstream 100 bases:

>100_bases
ACGTTGTTATTTTAATGAATTGTTTCTATATTTGTCTTGTCAATGCATTACATTACTAATGCAAAATTACTCTATTTGGT
TCAAATAACACTATAAAGAG

Downstream 100 bases:

>100_bases
AAGATAAAGAGTTCAGAATGAGTGCCAAGACACTGATCCTCCCCTTGTTTCTTATACTTTTGTGCTGTGTATTCGGATGC
CGGAACAAACATCATACCGA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MLIIGIAGGTGSGKTTVVRKMIESLPVGEVVLLPQDSYYKDSSHVPVEERQNINFDHPDAFEWSLLSKHVMMLKEGKSIE
QPTYSYLTCTRQPETIHIEPREVVIIEGILALCDKKLRNMMDLKIFVDADPDERLIRVIQRDVIERGRTAEAVMERYTRV
LKPMHLQFIEPCKRYADLIVPEGGSNAVAIDILTMYIKKHLKNEE

Sequences:

>Translated_205_residues
MLIIGIAGGTGSGKTTVVRKMIESLPVGEVVLLPQDSYYKDSSHVPVEERQNINFDHPDAFEWSLLSKHVMMLKEGKSIE
QPTYSYLTCTRQPETIHIEPREVVIIEGILALCDKKLRNMMDLKIFVDADPDERLIRVIQRDVIERGRTAEAVMERYTRV
LKPMHLQFIEPCKRYADLIVPEGGSNAVAIDILTMYIKKHLKNEE
>Mature_205_residues
MLIIGIAGGTGSGKTTVVRKMIESLPVGEVVLLPQDSYYKDSSHVPVEERQNINFDHPDAFEWSLLSKHVMMLKEGKSIE
QPTYSYLTCTRQPETIHIEPREVVIIEGILALCDKKLRNMMDLKIFVDADPDERLIRVIQRDVIERGRTAEAVMERYTRV
LKPMHLQFIEPCKRYADLIVPEGGSNAVAIDILTMYIKKHLKNEE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=43.8095238095238, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=43.8095238095238, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI18699734, Length=206, Percent_Identity=38.8349514563107, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI13899253, Length=212, Percent_Identity=40.5660377358491, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI209863022, Length=145, Percent_Identity=41.3793103448276, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI87082034, Length=205, Percent_Identity=47.8048780487805, Blast_Score=201, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17539894, Length=202, Percent_Identity=42.5742574257426, Blast_Score=174, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17539892, Length=202, Percent_Identity=42.5742574257426, Blast_Score=174, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71981181, Length=211, Percent_Identity=33.175355450237, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6324339, Length=195, Percent_Identity=36.4102564102564, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320223, Length=96, Percent_Identity=34.375, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573516, Length=203, Percent_Identity=41.871921182266, Blast_Score=166, Evalue=8e-42,
Organism=Drosophila melanogaster, GI28573514, Length=203, Percent_Identity=41.871921182266, Blast_Score=166, Evalue=8e-42,
Organism=Drosophila melanogaster, GI28573512, Length=203, Percent_Identity=41.871921182266, Blast_Score=166, Evalue=8e-42,
Organism=Drosophila melanogaster, GI45550449, Length=203, Percent_Identity=41.871921182266, Blast_Score=166, Evalue=9e-42,
Organism=Drosophila melanogaster, GI221458995, Length=212, Percent_Identity=39.622641509434, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24649624, Length=206, Percent_Identity=39.8058252427184, Blast_Score=156, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23450; Mature: 23450

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00227 TUBULIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIGIAGGTGSGKTTVVRKMIESLPVGEVVLLPQDSYYKDSSHVPVEERQNINFDHPDA
CEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCC
FEWSLLSKHVMMLKEGKSIEQPTYSYLTCTRQPETIHIEPREVVIIEGILALCDKKLRNM
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHH
MDLKIFVDADPDERLIRVIQRDVIERGRTAEAVMERYTRVLKPMHLQFIEPCKRYADLIV
EEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
PEGGSNAVAIDILTMYIKKHLKNEE
CCCCCCEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLIIGIAGGTGSGKTTVVRKMIESLPVGEVVLLPQDSYYKDSSHVPVEERQNINFDHPDA
CEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCC
FEWSLLSKHVMMLKEGKSIEQPTYSYLTCTRQPETIHIEPREVVIIEGILALCDKKLRNM
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHH
MDLKIFVDADPDERLIRVIQRDVIERGRTAEAVMERYTRVLKPMHLQFIEPCKRYADLIV
EEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
PEGGSNAVAIDILTMYIKKHLKNEE
CCCCCCEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]