Click here to switch to the map view.

The map label for this gene is mltF [H]

Identifier: 29345593

GI number: 29345593

Start: 192751

End: 194139

Strand: Reverse

Name: mltF [H]

Synonym: BT_0183

Alternate gene names: 29345593

Gene position: 194139-192751 (Counterclockwise)

Preceding gene: 29345594

Following gene: 29345584

Centisome position: 3.1

GC content: 43.2

Gene sequence:

>1389_bases
ATGAGTGCCAAGACACTGATCCTCCCCTTGTTTCTTATACTTTTGTGCTGTGTATTCGGATGCCGGAACAAACATCATAC
CGAAAAGAATGAAACAGCACACGATCTTCCACAGATTAAAGACAGTGGAGAACTGGTTGTGCTGACACTCTATAGCTCTA
CTTCATATTTCATTTATCGCGGACAGGAAATGGGATTCCAATACGAACTCAGTGAACAGTTCGCTAAAAGTCTGGGACTG
AAACTCAGAATCGAGGTAGCCAGAAATGTCCGTGAATTGATTCAGAAATTACAGTCAGGCGAAGGAGATATGATCGCCTA
CAACCTGCCGATTACCAAAGAATGGAAAGACAGCCTTTTGTATTGCGGAGAAGACATAATCACCCATCAGGTTATCGTCC
AGCAAGGAAATGGAAAGCATAAACCATTGAAAGATGTAACGGAACTTATCGGCAAAGATATATATGTCAAACCAGGCAAA
TATTACGATCGCCTCGTGAATCTGAACAACGAACTGGGAGGTGGTATCCATATTCATAAGATAACGGGAGATAGCGTTAC
CGCGGAAGACTTAATCACCCAGGTAGCACAAGGTAAGATTCCCTATACCGTAGCCGATAATGATTTAGCCAAACTGAATA
AAACTTACTATCCCAATCTGAATATCGATCTTTCTATCAGTTTTGACCAGCGTTCTTCATGGGCTGTACGAAAAGACAGT
CCCGAACTGGCAGCCGCCGCCACAAACTGGCATAAAGAAAATATGACCTCTCCTGCCTATACGGCAAGTATGAAGCGTTA
CTTCGAGAATAGTAAAATGATGCCACACTCCCCCATCCTTTCACTTAAAGAAGGAAAAATATCACATTACGACGATTTAT
TCAAGAAATACGCCCAAGAGATCGGATGGGACTGGCGAATGCTGGCATCCCTCGCCTATACAGAATCAAACTTTGACACA
ACAGCCGTATCTTGGGCAGGAGCCAAAGGATTGATGCAATTGATGCCTGCCACTGCACGCGCAATGGGCGTACCCGCAGG
TAAAGAACAAAACCCGGAAGAAAGTATAAAAGCAGCCGTTAAATACATTGCCGCCACAGACCGAAGTTTCAATATGATCC
CTGACAAACAGGAACGGCTCAACTTCATACTGGCTTCTTACAATGCCGGCCTAGGACATATCTACGACGCCATGGCATTA
GCAAAAAAATACGGAAAGAATAACCTCGTATGGAAAGACAACGTCGAAAACTTCATCCTGCTCAAAAGCAATGAGGAATA
CTTCACCGATCCTGTTTGTAAAAATGGATATTTCCGTGGCATAGAAACGTTCAACTTCGTACGTGATATTCAGTCCCGGT
TCGAATCGTACAAAAAAAAGATAAAATAA

Upstream 100 bases:

>100_bases
TCGTTCCAGAAGGCGGCAGCAATGCAGTAGCTATCGATATATTAACAATGTATATCAAGAAACATTTGAAAAATGAAGAA
TGAAAGATAAAGAGTTCAGA

Downstream 100 bases:

>100_bases
GTAATAAGTATCAGGTAATAGGTAATAACCGTAGCTTATCAATAGTGTATCCGCACGGCTTATTACCTATTACTTATTAC
CTATTACTTATTTACTACTT

Product: transglycosylase

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSAKTLILPLFLILLCCVFGCRNKHHTEKNETAHDLPQIKDSGELVVLTLYSSTSYFIYRGQEMGFQYELSEQFAKSLGL
KLRIEVARNVRELIQKLQSGEGDMIAYNLPITKEWKDSLLYCGEDIITHQVIVQQGNGKHKPLKDVTELIGKDIYVKPGK
YYDRLVNLNNELGGGIHIHKITGDSVTAEDLITQVAQGKIPYTVADNDLAKLNKTYYPNLNIDLSISFDQRSSWAVRKDS
PELAAAATNWHKENMTSPAYTASMKRYFENSKMMPHSPILSLKEGKISHYDDLFKKYAQEIGWDWRMLASLAYTESNFDT
TAVSWAGAKGLMQLMPATARAMGVPAGKEQNPEESIKAAVKYIAATDRSFNMIPDKQERLNFILASYNAGLGHIYDAMAL
AKKYGKNNLVWKDNVENFILLKSNEEYFTDPVCKNGYFRGIETFNFVRDIQSRFESYKKKIK

Sequences:

>Translated_462_residues
MSAKTLILPLFLILLCCVFGCRNKHHTEKNETAHDLPQIKDSGELVVLTLYSSTSYFIYRGQEMGFQYELSEQFAKSLGL
KLRIEVARNVRELIQKLQSGEGDMIAYNLPITKEWKDSLLYCGEDIITHQVIVQQGNGKHKPLKDVTELIGKDIYVKPGK
YYDRLVNLNNELGGGIHIHKITGDSVTAEDLITQVAQGKIPYTVADNDLAKLNKTYYPNLNIDLSISFDQRSSWAVRKDS
PELAAAATNWHKENMTSPAYTASMKRYFENSKMMPHSPILSLKEGKISHYDDLFKKYAQEIGWDWRMLASLAYTESNFDT
TAVSWAGAKGLMQLMPATARAMGVPAGKEQNPEESIKAAVKYIAATDRSFNMIPDKQERLNFILASYNAGLGHIYDAMAL
AKKYGKNNLVWKDNVENFILLKSNEEYFTDPVCKNGYFRGIETFNFVRDIQSRFESYKKKIK
>Mature_461_residues
SAKTLILPLFLILLCCVFGCRNKHHTEKNETAHDLPQIKDSGELVVLTLYSSTSYFIYRGQEMGFQYELSEQFAKSLGLK
LRIEVARNVRELIQKLQSGEGDMIAYNLPITKEWKDSLLYCGEDIITHQVIVQQGNGKHKPLKDVTELIGKDIYVKPGKY
YDRLVNLNNELGGGIHIHKITGDSVTAEDLITQVAQGKIPYTVADNDLAKLNKTYYPNLNIDLSISFDQRSSWAVRKDSP
ELAAAATNWHKENMTSPAYTASMKRYFENSKMMPHSPILSLKEGKISHYDDLFKKYAQEIGWDWRMLASLAYTESNFDTT
AVSWAGAKGLMQLMPATARAMGVPAGKEQNPEESIKAAVKYIAATDRSFNMIPDKQERLNFILASYNAGLGHIYDAMALA
KKYGKNNLVWKDNVENFILLKSNEEYFTDPVCKNGYFRGIETFNFVRDIQSRFESYKKKIK

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=421, Percent_Identity=28.978622327791, Blast_Score=156, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 52492; Mature: 52360

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKTLILPLFLILLCCVFGCRNKHHTEKNETAHDLPQIKDSGELVVLTLYSSTSYFIYR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCEEEEEE
GQEMGFQYELSEQFAKSLGLKLRIEVARNVRELIQKLQSGEGDMIAYNLPITKEWKDSLL
CCCCCEEEHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
YCGEDIITHQVIVQQGNGKHKPLKDVTELIGKDIYVKPGKYYDRLVNLNNELGGGIHIHK
HCCHHHHHHHHHEECCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHCCCCCCCCCEEEEE
ITGDSVTAEDLITQVAQGKIPYTVADNDLAKLNKTYYPNLNIDLSISFDQRSSWAVRKDS
ECCCCCCHHHHHHHHHCCCCCEEECCCCHHHHCCCCCCCCCEEEEEEECCCCCCCEECCC
PELAAAATNWHKENMTSPAYTASMKRYFENSKMMPHSPILSLKEGKISHYDDLFKKYAQE
CCHHHHHHCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IGWDWRMLASLAYTESNFDTTAVSWAGAKGLMQLMPATARAMGVPAGKEQNPEESIKAAV
HCCCHHHHHHHHHCCCCCCCCEEEHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
KYIAATDRSFNMIPDKQERLNFILASYNAGLGHIYDAMALAKKYGKNNLVWKDNVENFIL
HHHHHCCCCCCCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCEEEE
LKSNEEYFTDPVCKNGYFRGIETFNFVRDIQSRFESYKKKIK
EECCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAKTLILPLFLILLCCVFGCRNKHHTEKNETAHDLPQIKDSGELVVLTLYSSTSYFIYR
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCEEEEEE
GQEMGFQYELSEQFAKSLGLKLRIEVARNVRELIQKLQSGEGDMIAYNLPITKEWKDSLL
CCCCCEEEHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
YCGEDIITHQVIVQQGNGKHKPLKDVTELIGKDIYVKPGKYYDRLVNLNNELGGGIHIHK
HCCHHHHHHHHHEECCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHCCCCCCCCCEEEEE
ITGDSVTAEDLITQVAQGKIPYTVADNDLAKLNKTYYPNLNIDLSISFDQRSSWAVRKDS
ECCCCCCHHHHHHHHHCCCCCEEECCCCHHHHCCCCCCCCCEEEEEEECCCCCCCEECCC
PELAAAATNWHKENMTSPAYTASMKRYFENSKMMPHSPILSLKEGKISHYDDLFKKYAQE
CCHHHHHHCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IGWDWRMLASLAYTESNFDTTAVSWAGAKGLMQLMPATARAMGVPAGKEQNPEESIKAAV
HCCCHHHHHHHHHCCCCCCCCEEEHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
KYIAATDRSFNMIPDKQERLNFILASYNAGLGHIYDAMALAKKYGKNNLVWKDNVENFIL
HHHHHCCCCCCCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCEEEE
LKSNEEYFTDPVCKNGYFRGIETFNFVRDIQSRFESYKKKIK
EECCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA