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The map label for this gene is mngR [H]

Identifier: 29143853

GI number: 29143853

Start: 3651353

End: 3652075

Strand: Reverse

Name: mngR [H]

Synonym: t3550

Alternate gene names: 29143853

Gene position: 3652075-3651353 (Counterclockwise)

Preceding gene: 29143854

Following gene: 29143849

Centisome position: 76.21

GC content: 50.9

Gene sequence:

>723_bases
TTGCAGGTTGATAAAACGAGCTTTACTCCGCTTTATAAGCAACTATTTTTTATCATCTGTCAGCAGATCCAGAACGGGTC
TTTGCCTTTGGGTAGCCAACTACCGACGCAAAAAGAGATTGCCAGATCCTACAACGTCTCGCTGATTGTGGTTAAACAGG
CCTGGAGCGAATTAATCAATGCGGGCATTATTTCGTCGCAGCGCGGGAGTGGTTCGGTGGTGTGCTCGGTGCCGGAAGGC
GTGAGCTACGGGCACACGTTTCGCGGTATTACCCGCGATCTCCAGGACGCCAGCGTGGCGATTGAGAACCGTATTCTGGA
AATCGCGCCGCGCCGCGCGCGCGACGCTCAGGCAGACGGCTTGAGCCTGCCCGCACAGCATCACTATCTCTATATTTCGC
GTATTCGTTGCCTGAATAACCGTCCGTTTAACCATGAAAAGATCTATCTCGATCTTAGCTTCTTTCCCGATCTGCAACTC
ACACCGCAGGCGCTGGAGCATACGTCGCTTTATTCGTTATTAAACGTCACAAGCGACTCGGCGATAGAAAAAGTTGAGGC
GATTTTACCTTCCGCTGACCTGTGCGAAAAATTGCAAATCGCCCCCAATAAACCGCTGTTATCCGTCGCCAGACAGACGT
TTCAGGCCGGGAAGGACAGCCCTTTTGAGTATTGCCGCTATTACGTGCTGTCTGAATACTTTGGTGAAATTCATTATCAC
TGA

Upstream 100 bases:

>100_bases
TCGATTTGGCAGAACTGGCCAGGCAAATCGCAGGGTAGCGACTTCACCCTGCCGGGGACGGTAAAACGTCCCCTGCTGGC
GAAGACGTGAGGTGCGCAGC

Downstream 100 bases:

>100_bases
TCTGTCCACTTAATCCTGCGATAACCCCACTATATCTGGCGTTTACCTGCCTGACTGTCCGTCGTATTCTTGCTGAAAAA
ATCGTCAGGAGACAGGTATG

Product: GntR family regulatory protein

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSYNVSLIVVKQAWSELINAGIISSQRGSGSVVCSVPEG
VSYGHTFRGITRDLQDASVAIENRILEIAPRRARDAQADGLSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPDLQL
TPQALEHTSLYSLLNVTSDSAIEKVEAILPSADLCEKLQIAPNKPLLSVARQTFQAGKDSPFEYCRYYVLSEYFGEIHYH

Sequences:

>Translated_240_residues
MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSYNVSLIVVKQAWSELINAGIISSQRGSGSVVCSVPEG
VSYGHTFRGITRDLQDASVAIENRILEIAPRRARDAQADGLSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPDLQL
TPQALEHTSLYSLLNVTSDSAIEKVEAILPSADLCEKLQIAPNKPLLSVARQTFQAGKDSPFEYCRYYVLSEYFGEIHYH
>Mature_240_residues
MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSYNVSLIVVKQAWSELINAGIISSQRGSGSVVCSVPEG
VSYGHTFRGITRDLQDASVAIENRILEIAPRRARDAQADGLSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPDLQL
TPQALEHTSLYSLLNVTSDSAIEKVEAILPSADLCEKLQIAPNKPLLSVARQTFQAGKDSPFEYCRYYVLSEYFGEIHYH

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=224, Percent_Identity=29.0178571428571, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27052; Mature: 27052

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSYNVSLIVVKQAWSELIN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHH
AGIISSQRGSGSVVCSVPEGVSYGHTFRGITRDLQDASVAIENRILEIAPRRARDAQADG
HCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCC
LSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPDLQLTPQALEHTSLYSLLNVTSDS
CCCCCHHHEEHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHH
AIEKVEAILPSADLCEKLQIAPNKPLLSVARQTFQAGKDSPFEYCRYYVLSEYFGEIHYH
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSYNVSLIVVKQAWSELIN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHH
AGIISSQRGSGSVVCSVPEGVSYGHTFRGITRDLQDASVAIENRILEIAPRRARDAQADG
HCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCC
LSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPDLQLTPQALEHTSLYSLLNVTSDS
CCCCCHHHEEHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHH
AIEKVEAILPSADLCEKLQIAPNKPLLSVARQTFQAGKDSPFEYCRYYVLSEYFGEIHYH
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]