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The map label for this gene is mocR [H]

Identifier: 29143818

GI number: 29143818

Start: 3610192

End: 3611673

Strand: Direct

Name: mocR [H]

Synonym: t3512

Alternate gene names: 29143818

Gene position: 3610192-3611673 (Clockwise)

Preceding gene: 29143815

Following gene: 29143822

Centisome position: 75.34

GC content: 60.26

Gene sequence:

>1482_bases
ATGAACACAGCGAATTTCGAGTCGATACATATCATGATCGACGCGCAAGCGTGGCGCAATCTACCGCTGCATCTGCGCCT
GTACCACGCTTTTCGCCAATTGGTAATTTCCGGTGCGTTGGCTGATGGCGCAAAGCTACCTTCCGCTCGCGCGCTGGCCC
AGCGGCTGCACCTTTCCAGGGATACCGTCGAAAATGCCTATTCCCAGCTTCAGCGCGACGGCTTTATGACCCGCAGGCAA
GGGGCCGGGAGTTTCGCCAGCCGCCAGGGGGTTCCGCATATTCAGGGGCAGCACAGCCTGCCGCCATCGCCTCGCCAGAC
GCCCACGCTTAGCGCCCGCTGGCAGACGATTGCCGATCGCGCCGTATCTTTCGATGCCCGCCGGGTGCAGACGTTTACGC
TCGGCCTTGCGGAAACGCGAAACTTCCCGCAAACCATTTGGCAGAATTTTGCCCGCCAGATCCAGCGCGAGCGGGCGCAT
ACGCTAATGCTGCATGGCGATCCGCAGGGAGAGCAGGAACTGCGCCAGCAAATTGCCCATTATCTCAATTTTGAACGCGG
CGCGAAGGTCGACGCGCAGCAGATTGTGATTGTCAGTGGCGCGCGTCAGGCATTCTGGCTATGCGGGCAACTGCTGGCAG
AGGCCGGGCAGTCGGTGGTGATGGAAAATCCAGGCTATCCCGGCGCGCGTCAGGCATTCTCTGCCGCACAGCTCAACCTT
CTTCCCATTGAAGTCGATGGAGACGGTATTCGGGTGGATAAACTGCCGCCTGCGCCGCTGGTTTACGTTACGCCGTCGCA
CCAGTTTCCCTCCGGTCATTTGCTCTCTCTGGCGCGGCGTCATGCCCTGATTGACTGGGCACAGGCGCATAATGCCTGGA
TTATCGAAGATGACTACGACAGTGAATTTCACTACAACGGCGCGCCCGTCGCCTGTATGCAGGGGTTAGATCGCGAGCAG
CGCACCCTGTATGTCGGCACCTTCAGCAAAACGCTCTACCCCGGTCTGCGCATTGGTTATCTGGTGGTGCCTGCGTCGCT
GGCCGCGCACTTTGCCGCTGCGCGTAATTTGCTTGATGGCGCAACGCCCGCGTTGACCCAATTGACGCTGGCGCGATTTA
TCGCATCCGGCCATTTTGCCGCCCATATCCGCACCATGCGCAGTATGTACGCGGTGCGGCAGGCGTGCCTGGCGCAGGCC
ATCAACCAGCATCTTAGTGATTGGGTGACGCCGGTAGTGACGCCCGGAGGATTACAAATGCCCTGCTGGCTGCATGAAGG
TATTGACGAACAACAGACCCTTAACGCCGCGCGGCGGGCCGGGTTAAACATCGCCGGGATGCGCCAGTTCTGGCTGACGC
ACCCCGCGCCCACGGGCTGGCTGTTGGGATTCGCCGCGTTTACCCCCTACGAGATTGAAAATGGAGTCAAGCTTCTGCGG
GCTGCATTATGCGCCGAAAACGTGCGCCAAGCCGGGCCATAA

Upstream 100 bases:

>100_bases
CTTCTTCATACGGTTCCGGGTGTTCTTCAACACATAAAAAATAAGGCGTAAATGATATGATTCAACGACTTTGGCGACGC
AGGGACGGGGGAACCAGAAG

Downstream 100 bases:

>100_bases
TCTCATAAGGGATGGTATCGCAGGCGGCAGCAACCTCTTCCAGCGTCTGGCTCACGCCAATAAACTCCACAACATCGCCA
GACGTTGGCATGATGGCGCT

Product: GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MNTANFESIHIMIDAQAWRNLPLHLRLYHAFRQLVISGALADGAKLPSARALAQRLHLSRDTVENAYSQLQRDGFMTRRQ
GAGSFASRQGVPHIQGQHSLPPSPRQTPTLSARWQTIADRAVSFDARRVQTFTLGLAETRNFPQTIWQNFARQIQRERAH
TLMLHGDPQGEQELRQQIAHYLNFERGAKVDAQQIVIVSGARQAFWLCGQLLAEAGQSVVMENPGYPGARQAFSAAQLNL
LPIEVDGDGIRVDKLPPAPLVYVTPSHQFPSGHLLSLARRHALIDWAQAHNAWIIEDDYDSEFHYNGAPVACMQGLDREQ
RTLYVGTFSKTLYPGLRIGYLVVPASLAAHFAAARNLLDGATPALTQLTLARFIASGHFAAHIRTMRSMYAVRQACLAQA
INQHLSDWVTPVVTPGGLQMPCWLHEGIDEQQTLNAARRAGLNIAGMRQFWLTHPAPTGWLLGFAAFTPYEIENGVKLLR
AALCAENVRQAGP

Sequences:

>Translated_493_residues
MNTANFESIHIMIDAQAWRNLPLHLRLYHAFRQLVISGALADGAKLPSARALAQRLHLSRDTVENAYSQLQRDGFMTRRQ
GAGSFASRQGVPHIQGQHSLPPSPRQTPTLSARWQTIADRAVSFDARRVQTFTLGLAETRNFPQTIWQNFARQIQRERAH
TLMLHGDPQGEQELRQQIAHYLNFERGAKVDAQQIVIVSGARQAFWLCGQLLAEAGQSVVMENPGYPGARQAFSAAQLNL
LPIEVDGDGIRVDKLPPAPLVYVTPSHQFPSGHLLSLARRHALIDWAQAHNAWIIEDDYDSEFHYNGAPVACMQGLDREQ
RTLYVGTFSKTLYPGLRIGYLVVPASLAAHFAAARNLLDGATPALTQLTLARFIASGHFAAHIRTMRSMYAVRQACLAQA
INQHLSDWVTPVVTPGGLQMPCWLHEGIDEQQTLNAARRAGLNIAGMRQFWLTHPAPTGWLLGFAAFTPYEIENGVKLLR
AALCAENVRQAGP
>Mature_493_residues
MNTANFESIHIMIDAQAWRNLPLHLRLYHAFRQLVISGALADGAKLPSARALAQRLHLSRDTVENAYSQLQRDGFMTRRQ
GAGSFASRQGVPHIQGQHSLPPSPRQTPTLSARWQTIADRAVSFDARRVQTFTLGLAETRNFPQTIWQNFARQIQRERAH
TLMLHGDPQGEQELRQQIAHYLNFERGAKVDAQQIVIVSGARQAFWLCGQLLAEAGQSVVMENPGYPGARQAFSAAQLNL
LPIEVDGDGIRVDKLPPAPLVYVTPSHQFPSGHLLSLARRHALIDWAQAHNAWIIEDDYDSEFHYNGAPVACMQGLDREQ
RTLYVGTFSKTLYPGLRIGYLVVPASLAAHFAAARNLLDGATPALTQLTLARFIASGHFAAHIRTMRSMYAVRQACLAQA
INQHLSDWVTPVVTPGGLQMPCWLHEGIDEQQTLNAARRAGLNIAGMRQFWLTHPAPTGWLLGFAAFTPYEIENGVKLLR
AALCAENVRQAGP

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=322, Percent_Identity=21.4285714285714, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI33469970, Length=322, Percent_Identity=21.4285714285714, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1790797, Length=402, Percent_Identity=26.1194029850746, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1787710, Length=393, Percent_Identity=26.4631043256997, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54691; Mature: 54691

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTANFESIHIMIDAQAWRNLPLHLRLYHAFRQLVISGALADGAKLPSARALAQRLHLSR
CCCCCCEEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DTVENAYSQLQRDGFMTRRQGAGSFASRQGVPHIQGQHSLPPSPRQTPTLSARWQTIADR
HHHHHHHHHHHHCCCCHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AVSFDARRVQTFTLGLAETRNFPQTIWQNFARQIQRERAHTLMLHGDPQGEQELRQQIAH
HHCCCHHHHEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHH
YLNFERGAKVDAQQIVIVSGARQAFWLCGQLLAEAGQSVVMENPGYPGARQAFSAAQLNL
HHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCEEE
LPIEVDGDGIRVDKLPPAPLVYVTPSHQFPSGHLLSLARRHALIDWAQAHNAWIIEDDYD
EEEEECCCCEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCC
SEFHYNGAPVACMQGLDREQRTLYVGTFSKTLYPGLRIGYLVVPASLAAHFAAARNLLDG
CCCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHCCCCEEEHEEEHHHHHHHHHHHHHHHCC
ATPALTQLTLARFIASGHFAAHIRTMRSMYAVRQACLAQAINQHLSDWVTPVVTPGGLQM
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PCWLHEGIDEQQTLNAARRAGLNIAGMRQFWLTHPAPTGWLLGFAAFTPYEIENGVKLLR
CHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
AALCAENVRQAGP
HHHHHHHHHHCCC
>Mature Secondary Structure
MNTANFESIHIMIDAQAWRNLPLHLRLYHAFRQLVISGALADGAKLPSARALAQRLHLSR
CCCCCCEEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DTVENAYSQLQRDGFMTRRQGAGSFASRQGVPHIQGQHSLPPSPRQTPTLSARWQTIADR
HHHHHHHHHHHHCCCCHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AVSFDARRVQTFTLGLAETRNFPQTIWQNFARQIQRERAHTLMLHGDPQGEQELRQQIAH
HHCCCHHHHEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHH
YLNFERGAKVDAQQIVIVSGARQAFWLCGQLLAEAGQSVVMENPGYPGARQAFSAAQLNL
HHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCEEE
LPIEVDGDGIRVDKLPPAPLVYVTPSHQFPSGHLLSLARRHALIDWAQAHNAWIIEDDYD
EEEEECCCCEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCC
SEFHYNGAPVACMQGLDREQRTLYVGTFSKTLYPGLRIGYLVVPASLAAHFAAARNLLDG
CCCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHCCCCEEEHEEEHHHHHHHHHHHHHHHCC
ATPALTQLTLARFIASGHFAAHIRTMRSMYAVRQACLAQAINQHLSDWVTPVVTPGGLQM
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PCWLHEGIDEQQTLNAARRAGLNIAGMRQFWLTHPAPTGWLLGFAAFTPYEIENGVKLLR
CHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
AALCAENVRQAGP
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]