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The map label for this gene is murB [H]

Identifier: 29143799

GI number: 29143799

Start: 3579168

End: 3580196

Strand: Reverse

Name: murB [H]

Synonym: t3489

Alternate gene names: 29143799

Gene position: 3580196-3579168 (Counterclockwise)

Preceding gene: 161486778

Following gene: 29143798

Centisome position: 74.71

GC content: 53.06

Gene sequence:

>1029_bases
ATGACCCATTCCCTAAAACCCTGGAATACCTTCGGCATTGATCATTGTGCAAAGCACATCGTATGCGCTGAAAACGAACA
ACAACTACTGAGCGCCTGGCAGCAAGCAACTCGTGAGGGACTGCCGGTTATGATCCTGGGTGAAGGAAGCAACGTCCTGT
TTCTGGAAAATTACGCCGGCACCGTGATCCTTAACCGCCTGAAAGGCATTGAGGTGAATGAAACCGCGGACGCCTGGCAC
CTACACGTCGGCGCAGGCGAAAACTGGCATCAGCTGGTTCGCTATGCGCTGGACAACAACATGCCCGGCCTGGAGAATCT
GGCGCTCATCCCTGGCTGCGTTGGTTCCTCGCCTATACAGAATATTGGCGCGTATGGCGTAGAACTACATCGCGTCTGCG
ACTACGTTGACTGCGTTGAACTGGAAACGGGAAAACGTCTGCGTTTGTCCGCGGCGGAATGCCGTTTCGGCTATCGTGAC
AGTATCTTCAAAAATGAATATCAGGATCGCGTTGCGATCGTCGCGGTGGGTCTGCGTTTGTCAAAGCAATGGCAGCCGGT
GTTGACCTATGGCGATCTTACTCGTCTGGACCCGAAAACGGTCACCGCGCAACAGGTGTTTGATGCTGTATGCCATATGC
GCACCACAAAATTGCCGGATCCTAAAGTGAATGGCAATGCGGGCAGCTTTTTTAAAAATCCCGTTGTCGCAGCCGATATC
GCTATGGAACTGTTAGAACGATTTCCCAACGCGCCGCATTACCCTCAGGCAGACGGCTCAGTGAAGCTGGCGGCAGGCTG
GCTGATAGATCAATGTCAGTTGAAAGGCGTCACCATTGGCGGCGCTGCGGTGCATCGCCAACAGGCGCTGGTATTGATTA
ATGCGAATGATGCGACAAGTAAAGATGTGGTGGCGCTGGCGCATCATGTCCGGCAAAAAGTGGGTGAAAAATTTAATGTC
TGGCTGGAGCCTGAGGTTCGCTTTATTGGTCAGTTCGGAGAGGTGAACGCTGTGGAGAGCATTGCATGA

Upstream 100 bases:

>100_bases
ACAATGCCTGTGTACACCGCCTTATTCCGTCGACATAACCGCAAGCCTTCCCAACCCAGATACGGTAAACTATTGCCGAT
TGAGTATCAGGAAAGCAGCC

Downstream 100 bases:

>100_bases
AAGATACTACCGTTCCCCTGACGCTGATCTCACTACTTGCCGACGGAGAGTTTCACTCAGGCGAGCAGTTGGGTGAACGG
CTGGGAATGAGCCGTGCGGC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWH
LHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQNIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRD
SIFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVTIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNV
WLEPEVRFIGQFGEVNAVESIA

Sequences:

>Translated_342_residues
MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWH
LHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQNIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRD
SIFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVTIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNV
WLEPEVRFIGQFGEVNAVESIA
>Mature_341_residues
THSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWHL
HVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQNIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRDS
IFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADIA
MELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVTIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNVW
LEPEVRFIGQFGEVNAVESIA

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=342, Percent_Identity=81.8713450292398, Blast_Score=592, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37742; Mature: 37610

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAG
CCCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCC
TVILNRLKGIEVNETADAWHLHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQ
CHHHHHHCCCEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHH
NIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRDSIFKNEYQDRVAIVAVGLRL
HHHHCCCHHHHHHCHHHHEEECCCCEEEEEHHHHCCCCHHHHHHHHHHCEEEEEEECCHH
SKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHH
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVTIGGAAVHRQQALVLINANDATS
HHHHHHHCCCCCCCCCCCCCEEEEECEEEEEEEECEEEECCHHHCCCEEEEEEECCCCCC
KDVVALAHHVRQKVGEKFNVWLEPEVRFIGQFGEVNAVESIA
HHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHCC
>Mature Secondary Structure 
THSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAG
CCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCC
TVILNRLKGIEVNETADAWHLHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQ
CHHHHHHCCCEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHH
NIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRDSIFKNEYQDRVAIVAVGLRL
HHHHCCCHHHHHHCHHHHEEECCCCEEEEEHHHHCCCCHHHHHHHHHHCEEEEEEECCHH
SKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHH
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVTIGGAAVHRQQALVLINANDATS
HHHHHHHCCCCCCCCCCCCCEEEEECEEEEEEEECEEEECCHHHCCCEEEEEEECCCCCC
KDVVALAHHVRQKVGEKFNVWLEPEVRFIGQFGEVNAVESIA
HHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA