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The map label for this gene is ampH [H]

Identifier: 29142875

GI number: 29142875

Start: 2559577

End: 2560734

Strand: Direct

Name: ampH [H]

Synonym: t2489

Alternate gene names: 29142875

Gene position: 2559577-2560734 (Clockwise)

Preceding gene: 29142872

Following gene: 29142878

Centisome position: 53.41

GC content: 53.54

Gene sequence:

>1158_bases
TTGAAACGTAGTCTGCTTTTTACTGCCATGCTGTTTGCGGCATCACTTACTTCTGTCCAGGCGGCTCAGCCGATTGCCGA
TCCGGTTTTTGCCTCTGATATCGTTGATCGTTATGCCGAGCATATCTTTTATGGTAGCGGCGCCACGGGCATGGCGCTGG
TGGTGATCGACGGCAATCAACGCGTGTTTCGTAGTTTCGGTGACACCAGACCGGGCAATAATGTTCGTCCACAGCTTGAC
TCGGTCATTCGTATCGCTTCTCTCACCAAGCTCATGACCAGTGAAATGTTGGTAAAATTGCTCGATCAGGGAACGGTAAA
ATTAAACGATCCGCTCAGCAAATATGCGCCTCCCGGCGCGCATGTCCCGACGTATCAAGGCACGCCGATTACGTTGGTCA
ACTTAGCGACCCACACCAGCGCGCTTCCGCGAGAACAGCCCGGCGGCGCGGCGCATCGTCCGGTATTTGTCTGGCCAACC
CGCGAACAACGCTGGAACTGGCTCTCCACAGCAACGTTAAAAGTCGCGCCCGGTTCACAGGCGGCCTATTCCAATCTGGC
GTTCGACCTGTTAGCCGACGCGCTGGCGACCGCCTCCGGCAAACCTTATACGCAACTGTTTGAAGAAAAGATTACCCGCC
CGCTGGGAATGAAAGACACCACGTTTACCCCCTCTCCCGATCAGTGTAAGCGTCTGATGGTGGCAGAGAAAGGCGCAAGC
CCCTGTAATAATACGCTGGCTGCCATTGGCAGCGGCGGAGTCTATTCTACGCCAGGAGATATGATGCGCTGGATGCAACA
GTATCTGTCGTCAGATTTCTATCACCGTAGCCATCAGGCCGATCGTATGCAAACGTTGATTTATCAGCGCGCACAGTTAA
AGAAAATCATCGGGATGGACGTACCGGGTAAAGCCGACGCGCTCGGTCTGGGCTGGGTCTATATGGCGCCAAAAGACGGA
CGTCCTGGCATTATCCAGAAAACGGGAGGCGGCGGCGGTTTTATTACCTATATGGCGATGATCCCACAATATAATATTGG
CGCTTTTGTGGTCGTAACCCGTTCCCCCCTCACCCGTTTTACCAATATGAGCGACGGGATTAACGATTTGGTTACTGAGC
TAAGCGGCAATAAACCGATTGCTATTCCTGCATCCTGA

Upstream 100 bases:

>100_bases
ACGTTTTTTCACCCACTTTTTTCTCTTTAACGTTTTGCAATGTGCCGCCGGGTAGTATAAATACGCATAACCACCGTTAT
TTCACTTATGGACATCACCG

Downstream 100 bases:

>100_bases
GTCGTCGCGCCTCGCGCTATATCAGACGAGGCGCGACATTTTTGTTAATATTCGGAGGGCAAACGGTTAATACTGATCAA
TTTGCCTTTATTCATTTCAA

Product: beta-lactam binding protein AmpH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKRSLLFTAMLFAASLTSVQAAQPIADPVFASDIVDRYAEHIFYGSGATGMALVVIDGNQRVFRSFGDTRPGNNVRPQLD
SVIRIASLTKLMTSEMLVKLLDQGTVKLNDPLSKYAPPGAHVPTYQGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
REQRWNWLSTATLKVAPGSQAAYSNLAFDLLADALATASGKPYTQLFEEKITRPLGMKDTTFTPSPDQCKRLMVAEKGAS
PCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYHRSHQADRMQTLIYQRAQLKKIIGMDVPGKADALGLGWVYMAPKDG
RPGIIQKTGGGGGFITYMAMIPQYNIGAFVVVTRSPLTRFTNMSDGINDLVTELSGNKPIAIPAS

Sequences:

>Translated_385_residues
MKRSLLFTAMLFAASLTSVQAAQPIADPVFASDIVDRYAEHIFYGSGATGMALVVIDGNQRVFRSFGDTRPGNNVRPQLD
SVIRIASLTKLMTSEMLVKLLDQGTVKLNDPLSKYAPPGAHVPTYQGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
REQRWNWLSTATLKVAPGSQAAYSNLAFDLLADALATASGKPYTQLFEEKITRPLGMKDTTFTPSPDQCKRLMVAEKGAS
PCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYHRSHQADRMQTLIYQRAQLKKIIGMDVPGKADALGLGWVYMAPKDG
RPGIIQKTGGGGGFITYMAMIPQYNIGAFVVVTRSPLTRFTNMSDGINDLVTELSGNKPIAIPAS
>Mature_385_residues
MKRSLLFTAMLFAASLTSVQAAQPIADPVFASDIVDRYAEHIFYGSGATGMALVVIDGNQRVFRSFGDTRPGNNVRPQLD
SVIRIASLTKLMTSEMLVKLLDQGTVKLNDPLSKYAPPGAHVPTYQGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
REQRWNWLSTATLKVAPGSQAAYSNLAFDLLADALATASGKPYTQLFEEKITRPLGMKDTTFTPSPDQCKRLMVAEKGAS
PCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYHRSHQADRMQTLIYQRAQLKKIIGMDVPGKADALGLGWVYMAPKDG
RPGIIQKTGGGGGFITYMAMIPQYNIGAFVVVTRSPLTRFTNMSDGINDLVTELSGNKPIAIPAS

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI239747261, Length=356, Percent_Identity=28.0898876404494, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI239752721, Length=356, Percent_Identity=28.0898876404494, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI239741085, Length=356, Percent_Identity=28.0898876404494, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786574, Length=385, Percent_Identity=91.6883116883117, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI87082101, Length=246, Percent_Identity=26.4227642276423, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 41780; Mature: 41780

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSLLFTAMLFAASLTSVQAAQPIADPVFASDIVDRYAEHIFYGSGATGMALVVIDGNQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCEEEEEECCCH
RVFRSFGDTRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLDQGTVKLNDPLSKYAPPGA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCC
HVPTYQGTPITLVNLATHTSALPREQPGGAAHRPVFVWPTREQRWNWLSTATLKVAPGSQ
CCCCCCCCCEEEEEECHHHCCCCCCCCCCCCCCCEEEECCHHHHCCEEEEEEEEECCCCH
AAYSNLAFDLLADALATASGKPYTQLFEEKITRPLGMKDTTFTPSPDQCKRLMVAEKGAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
PCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYHRSHQADRMQTLIYQRAQLKKIIGMD
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VPGKADALGLGWVYMAPKDGRPGIIQKTGGGGGFITYMAMIPQYNIGAFVVVTRSPLTRF
CCCCCCCEEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHH
TNMSDGINDLVTELSGNKPIAIPAS
CCCCCCHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure
MKRSLLFTAMLFAASLTSVQAAQPIADPVFASDIVDRYAEHIFYGSGATGMALVVIDGNQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCEEEEEECCCH
RVFRSFGDTRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLDQGTVKLNDPLSKYAPPGA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCC
HVPTYQGTPITLVNLATHTSALPREQPGGAAHRPVFVWPTREQRWNWLSTATLKVAPGSQ
CCCCCCCCCEEEEEECHHHCCCCCCCCCCCCCCCEEEECCHHHHCCEEEEEEEEECCCCH
AAYSNLAFDLLADALATASGKPYTQLFEEKITRPLGMKDTTFTPSPDQCKRLMVAEKGAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
PCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYHRSHQADRMQTLIYQRAQLKKIIGMD
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VPGKADALGLGWVYMAPKDGRPGIIQKTGGGGGFITYMAMIPQYNIGAFVVVTRSPLTRF
CCCCCCCEEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHH
TNMSDGINDLVTELSGNKPIAIPAS
CCCCCCHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]