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The map label for this gene is tsx

Identifier: 29142838

GI number: 29142838

Start: 2520492

End: 2521355

Strand: Direct

Name: tsx

Synonym: t2450

Alternate gene names: 29142838

Gene position: 2520492-2521355 (Clockwise)

Preceding gene: 29142837

Following gene: 29142839

Centisome position: 52.6

GC content: 51.16

Gene sequence:

>864_bases
ATGAAAAAAACTTTACTCGCAGTCAGCGCAGCGCTGGCGCTCACCTCATCTTTTACTGCTAACGCAGCAGAAAATGATCA
GCCGCAGTATTTGTCCGACTGGTGGCACCAGAGCGTAAACGTGGTAGGCAGCTACCATACCCGTTTCTCGCCGAAATTGA
ACAACGACGTCTATCTGGAATATGAAGCATTTGCCAAAAAAGACTGGTTTGATTTCTACGGCTATATCGATATTCCCAAA
ACCTTTGATTGGGGTAACGGCAACGATAAAGGTATCTGGTCCGACGGTTCTCCGCTGTTCATGGAAATCGAACCGCGTTT
CTCGATTGATAAGCTGACCGGCGCAGACCTGAGCTTTGGCCCGTTTAAAGAGTGGTATTTCGCCAACAACTACATCTACG
ATATGGGCGATAACAAAGCCAGCCGCCAGAGCACATGGTATATGGGTCTGGGGACCGATATCGACACCGGCCTGCCGATG
GGTCTGTCGCTGAACGTGTATGCGAAATATCAGTGGCAAAACTACGGCGCGTCCAATGAAAACGAATGGGACGGCTACCG
TTTCAAAGTGAAATACTTCGTCCCCATCACCGATCTGTGGGGCGGTAAACTGAGCTATATCGGCTTTACCAACTTTGACT
GGGGATCTGATTTAGGCGACGATCCGAACCGTACCAGCAACTCCATCGCTTCCAGCCATATCCTGGCGCTGAACTACGAT
CACTGGCACTACTCGGTCGTTGCGCGTTACTTCCATAACGGCGGACAGTGGCAGAATGGCGCCAAACTGAACTGGGGCGA
CGGCGATTTCAGCGCGAAATCTACCGGCTGGGGCGGTTACCTGGTCGTGGGTTACAACTTCTAA

Upstream 100 bases:

>100_bases
CAATGATTTTTATAATAGGCTCCGCAGAAACACGAAATATTTAGAAACGCAAATTGCGTTCTTTTCACTCCCGCAAGGGA
TTTCAAACAGTGGCATACAT

Downstream 100 bases:

>100_bases
ACCTGCAAAAAAGCCAGAGGTCGTCCTCTGGCCCGTTTCGGGCGCATGCTGCCATGCGGCGGCGAGTCGCGCCCACTTCA
CATTACTTCCGGCGATGCCA

Product: nucleoside-specific channel-forming protein tsx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKKTLLAVSAALALTSSFTANAAENDQPQYLSDWWHQSVNVVGSYHTRFSPKLNNDVYLEYEAFAKKDWFDFYGYIDIPK
TFDWGNGNDKGIWSDGSPLFMEIEPRFSIDKLTGADLSFGPFKEWYFANNYIYDMGDNKASRQSTWYMGLGTDIDTGLPM
GLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPITDLWGGKLSYIGFTNFDWGSDLGDDPNRTSNSIASSHILALNYD
HWHYSVVARYFHNGGQWQNGAKLNWGDGDFSAKSTGWGGYLVVGYNF

Sequences:

>Translated_287_residues
MKKTLLAVSAALALTSSFTANAAENDQPQYLSDWWHQSVNVVGSYHTRFSPKLNNDVYLEYEAFAKKDWFDFYGYIDIPK
TFDWGNGNDKGIWSDGSPLFMEIEPRFSIDKLTGADLSFGPFKEWYFANNYIYDMGDNKASRQSTWYMGLGTDIDTGLPM
GLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPITDLWGGKLSYIGFTNFDWGSDLGDDPNRTSNSIASSHILALNYD
HWHYSVVARYFHNGGQWQNGAKLNWGDGDFSAKSTGWGGYLVVGYNF
>Mature_287_residues
MKKTLLAVSAALALTSSFTANAAENDQPQYLSDWWHQSVNVVGSYHTRFSPKLNNDVYLEYEAFAKKDWFDFYGYIDIPK
TFDWGNGNDKGIWSDGSPLFMEIEPRFSIDKLTGADLSFGPFKEWYFANNYIYDMGDNKASRQSTWYMGLGTDIDTGLPM
GLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPITDLWGGKLSYIGFTNFDWGSDLGDDPNRTSNSIASSHILALNYD
HWHYSVVARYFHNGGQWQNGAKLNWGDGDFSAKSTGWGGYLVVGYNF

Specific function: Constitutes the receptor for colicin K and phage T6, and functions as substrate-specific channel for nucleosides and deoxynucleosides

COG id: COG3248

COG function: function code M; Nucleoside-binding outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786612, Length=295, Percent_Identity=81.3559322033898, Blast_Score=471, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TSX_SALTI (P0A262)

Other databases:

- EMBL:   AL627266
- EMBL:   AE014613
- RefSeq:   NP_455008.1
- RefSeq:   NP_806180.1
- ProteinModelPortal:   P0A262
- SMR:   P0A262
- PRIDE:   P0A262
- GeneID:   1067468
- GeneID:   1246926
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2450
- KEGG:   sty:STY0451
- HOGENOM:   HBG416540
- OMA:   EPRISID
- ProtClustDB:   PRK15106
- BioCyc:   SENT209261:T2450-MONOMER
- BioCyc:   SENT220341:STY0451-MONOMER
- InterPro:   IPR003055
- InterPro:   IPR018013
- PRINTS:   PR01277

Pfam domain/function: PF03502 Channel_Tsx

EC number: NA

Molecular weight: Translated: 32778; Mature: 32778

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLLAVSAALALTSSFTANAAENDQPQYLSDWWHQSVNVVGSYHTRFSPKLNNDVYLE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEEEEEECEEECCCCCCCEEEE
YEAFAKKDWFDFYGYIDIPKTFDWGNGNDKGIWSDGSPLFMEIEPRFSIDKLTGADLSFG
EHHHCCCCCEEEEEEEECCCEECCCCCCCCCEECCCCEEEEEECCCCCEECCCCCCCCCC
PFKEWYFANNYIYDMGDNKASRQSTWYMGLGTDIDTGLPMGLSLNVYAKYQWQNYGASNE
CCCCEEEECCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCC
NEWDGYRFKVKYFVPITDLWGGKLSYIGFTNFDWGSDLGDDPNRTSNSIASSHILALNYD
CCCCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
HWHYSVVARYFHNGGQWQNGAKLNWGDGDFSAKSTGWGGYLVVGYNF
CHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MKKTLLAVSAALALTSSFTANAAENDQPQYLSDWWHQSVNVVGSYHTRFSPKLNNDVYLE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEEEEEECEEECCCCCCCEEEE
YEAFAKKDWFDFYGYIDIPKTFDWGNGNDKGIWSDGSPLFMEIEPRFSIDKLTGADLSFG
EHHHCCCCCEEEEEEEECCCEECCCCCCCCCEECCCCEEEEEECCCCCEECCCCCCCCCC
PFKEWYFANNYIYDMGDNKASRQSTWYMGLGTDIDTGLPMGLSLNVYAKYQWQNYGASNE
CCCCEEEECCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCC
NEWDGYRFKVKYFVPITDLWGGKLSYIGFTNFDWGSDLGDDPNRTSNSIASSHILALNYD
CCCCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
HWHYSVVARYFHNGGQWQNGAKLNWGDGDFSAKSTGWGGYLVVGYNF
CHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504