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The map label for this gene is scsB [H]

Identifier: 29142237

GI number: 29142237

Start: 1868272

End: 1870158

Strand: Reverse

Name: scsB [H]

Synonym: t1806

Alternate gene names: 29142237

Gene position: 1870158-1868272 (Counterclockwise)

Preceding gene: 29142238

Following gene: 29142236

Centisome position: 39.03

GC content: 58.13

Gene sequence:

>1887_bases
ATGATGATTTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTCTCCTGGGCGGCGGAAAGCGGCTG
GCTGCGTTCGCCCGATAACGACCATGCCAGCATACGGCTACGTGCCGATACGTCCGCTAACAGTGAGACCCGGCTGTTGC
TGGATGTCAAACTGGAAAACGGCTGGAAAACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCCTGG
AAAGGCGACATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTGGCGAATATCACCACCCAGGGATA
TCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGTACGCCGCCGGCGACCTTGCGCGGTGTGTTGACGTTATCAACCT
GCAGCAATGTTTGTCTGTTGACCGATTACCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGACTAT
GCGCGGGCGATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTTGGCTATCGCCCGGGAGAACTGGT
GGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCCGGGCTCTATCTTGACACCATAGATGACGTCGATTTTGCGAAGC
CTCGCCTGCGCGTAGAGGGCGACAGGTTACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGATTTG
CGCGACAAATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACGCAAACCATTGGCGCTGCGCCAGC
GCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAAGTTGTAATGATGGCGCTAATCGGCGGACTGATTCTTAATTTAA
TGCCCTGCGTACTGCCTGTTCTGGGCATGAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATCAGG
CGACAATTTTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCGTTTATGACCCTCCTTCGCCTGTC
AAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAATGCATGGTTTATTGGTTTTATGGCGCTGGTGATGTTGTTGTTTA
GCGCCAGCCTGTTCGGGCTTTTTGAGTTCAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAACGGT
ATGTCGGGACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGCGCGCCGTTTCTGGGCACGGCGGT
CGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGGGGGCTGTTCCTTGCGCTTGGCCTGGGAATGAGCGCGCCGTGGC
TACTGGTCGCGATACGACCAGGGCTTGCGCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATCCTC
GGTCTGATGATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTCGGCTTCACTGCGTCAAAGAGCGC
GCAAGACACGGCTCAGTGGCAACCGTTGAGTGAACAGGCAATCCAGTCGGCGCTGGCGCAGCATAAGCGGGTATTTGTCG
ATGTCACTGCGGACTGGTGTATTACCTGTAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCCTTG
CAACAGCCGGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATTACAGATTTTCTGAAAACGCGCGG
CCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCCGGTTTGCCGGAAGGGGAGGCACTGCCCACTTTGCTGACCCGCG
ATGCGGTATTACAAACGTTGAAAAAAGCGAAAGGAATAACCCAATGA

Upstream 100 bases:

>100_bases
TTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGTGAATGACAGACCGGTTATTACTAACGGTTAATTA
CTCATTCACGGAGAAAAAAT

Downstream 100 bases:

>100_bases
AATACATGATTGTTTTACTGCTGGCGCTGTTTTCGACGCTGAGCATCGCGCAAGAAACCGCTCCTTTTACGCCGGATCAG
GAAAAGCAGATTAAAAATCT

Product: copper sensitivity suppressor membrane protein B

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MMILFRRILFCLLWLWLPVSWAAESGWLRSPDNDHASIRLRADTSANSETRLLLDVKLENGWKTYWRAPGEGGVAPSIAW
KGDMPEVSWFWPTPSRFDVANITTQGYHDEVTFPMIVRGTPPATLRGVLTLSTCSNVCLLTDYPFSVTPTVQNADFAHDY
ARAMGKVPLRSGLTDSLDVGYRPGELVVTATRAAGWSSPGLYLDTIDDVDFAKPRLRVEGDRLQATVPVTDSWGEKAPDL
RDKSLTLVLADGAIAQESTQTIGAAPAQTPDNAALPFWQVVMMALIGGLILNLMPCVLPVLGMKLGSILLVEEKSRSHIR
RQFLASVAGIIASFMALAAFMTLLRLSNHALAWGVQFQNAWFIGFMALVMLLFSASLFGLFEFRLPSSMTTKLATYGGNG
MSGHFWQGAFATLLATPCSAPFLGTAVAVALTASLPTLWGLFLALGLGMSAPWLLVAIRPGLALRLPRPGRWMNVLRRIL
GLMMLGSAIWLATLLLPHFGFTASKSAQDTAQWQPLSEQAIQSALAQHKRVFVDVTADWCITCKVNKYNVLQKEDVQAAL
QQPDVVALRGDWTLPSDAITDFLKTRGQVAVPFNQVYGPGLPEGEALPTLLTRDAVLQTLKKAKGITQ

Sequences:

>Translated_628_residues
MMILFRRILFCLLWLWLPVSWAAESGWLRSPDNDHASIRLRADTSANSETRLLLDVKLENGWKTYWRAPGEGGVAPSIAW
KGDMPEVSWFWPTPSRFDVANITTQGYHDEVTFPMIVRGTPPATLRGVLTLSTCSNVCLLTDYPFSVTPTVQNADFAHDY
ARAMGKVPLRSGLTDSLDVGYRPGELVVTATRAAGWSSPGLYLDTIDDVDFAKPRLRVEGDRLQATVPVTDSWGEKAPDL
RDKSLTLVLADGAIAQESTQTIGAAPAQTPDNAALPFWQVVMMALIGGLILNLMPCVLPVLGMKLGSILLVEEKSRSHIR
RQFLASVAGIIASFMALAAFMTLLRLSNHALAWGVQFQNAWFIGFMALVMLLFSASLFGLFEFRLPSSMTTKLATYGGNG
MSGHFWQGAFATLLATPCSAPFLGTAVAVALTASLPTLWGLFLALGLGMSAPWLLVAIRPGLALRLPRPGRWMNVLRRIL
GLMMLGSAIWLATLLLPHFGFTASKSAQDTAQWQPLSEQAIQSALAQHKRVFVDVTADWCITCKVNKYNVLQKEDVQAAL
QQPDVVALRGDWTLPSDAITDFLKTRGQVAVPFNQVYGPGLPEGEALPTLLTRDAVLQTLKKAKGITQ
>Mature_628_residues
MMILFRRILFCLLWLWLPVSWAAESGWLRSPDNDHASIRLRADTSANSETRLLLDVKLENGWKTYWRAPGEGGVAPSIAW
KGDMPEVSWFWPTPSRFDVANITTQGYHDEVTFPMIVRGTPPATLRGVLTLSTCSNVCLLTDYPFSVTPTVQNADFAHDY
ARAMGKVPLRSGLTDSLDVGYRPGELVVTATRAAGWSSPGLYLDTIDDVDFAKPRLRVEGDRLQATVPVTDSWGEKAPDL
RDKSLTLVLADGAIAQESTQTIGAAPAQTPDNAALPFWQVVMMALIGGLILNLMPCVLPVLGMKLGSILLVEEKSRSHIR
RQFLASVAGIIASFMALAAFMTLLRLSNHALAWGVQFQNAWFIGFMALVMLLFSASLFGLFEFRLPSSMTTKLATYGGNG
MSGHFWQGAFATLLATPCSAPFLGTAVAVALTASLPTLWGLFLALGLGMSAPWLLVAIRPGLALRLPRPGRWMNVLRRIL
GLMMLGSAIWLATLLLPHFGFTASKSAQDTAQWQPLSEQAIQSALAQHKRVFVDVTADWCITCKVNKYNVLQKEDVQAAL
QQPDVVALRGDWTLPSDAITDFLKTRGQVAVPFNQVYGPGLPEGEALPTLLTRDAVLQTLKKAKGITQ

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=418, Percent_Identity=25.5980861244019, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 68597; Mature: 68597

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILFRRILFCLLWLWLPVSWAAESGWLRSPDNDHASIRLRADTSANSETRLLLDVKLEN
CHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECC
GWKTYWRAPGEGGVAPSIAWKGDMPEVSWFWPTPSRFDVANITTQGYHDEVTFPMIVRGT
CCEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCEEEECEECCCCCCCCCEEEEECC
PPATLRGVLTLSTCSNVCLLTDYPFSVTPTVQNADFAHDYARAMGKVPLRSGLTDSLDVG
CCHHHHHEEEEECCCCEEEEECCCCEECCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCCC
YRPGELVVTATRAAGWSSPGLYLDTIDDVDFAKPRLRVEGDRLQATVPVTDSWGEKAPDL
CCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCC
RDKSLTLVLADGAIAQESTQTIGAAPAQTPDNAALPFWQVVMMALIGGLILNLMPCVLPV
CCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGMKLGSILLVEEKSRSHIRRQFLASVAGIIASFMALAAFMTLLRLSNHALAWGVQFQNA
HHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCH
WFIGFMALVMLLFSASLFGLFEFRLPSSMTTKLATYGGNGMSGHFWQGAFATLLATPCSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
PFLGTAVAVALTASLPTLWGLFLALGLGMSAPWLLVAIRPGLALRLPRPGRWMNVLRRIL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHH
GLMMLGSAIWLATLLLPHFGFTASKSAQDTAQWQPLSEQAIQSALAQHKRVFVDVTADWC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCEEEEEEECCEE
ITCKVNKYNVLQKEDVQAALQQPDVVALRGDWTLPSDAITDFLKTRGQVAVPFNQVYGPG
EEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEECHHHHCCCC
LPEGEALPTLLTRDAVLQTLKKAKGITQ
CCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMILFRRILFCLLWLWLPVSWAAESGWLRSPDNDHASIRLRADTSANSETRLLLDVKLEN
CHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECC
GWKTYWRAPGEGGVAPSIAWKGDMPEVSWFWPTPSRFDVANITTQGYHDEVTFPMIVRGT
CCEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCEEEECEECCCCCCCCCEEEEECC
PPATLRGVLTLSTCSNVCLLTDYPFSVTPTVQNADFAHDYARAMGKVPLRSGLTDSLDVG
CCHHHHHEEEEECCCCEEEEECCCCEECCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCCC
YRPGELVVTATRAAGWSSPGLYLDTIDDVDFAKPRLRVEGDRLQATVPVTDSWGEKAPDL
CCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCC
RDKSLTLVLADGAIAQESTQTIGAAPAQTPDNAALPFWQVVMMALIGGLILNLMPCVLPV
CCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGMKLGSILLVEEKSRSHIRRQFLASVAGIIASFMALAAFMTLLRLSNHALAWGVQFQNA
HHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCH
WFIGFMALVMLLFSASLFGLFEFRLPSSMTTKLATYGGNGMSGHFWQGAFATLLATPCSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
PFLGTAVAVALTASLPTLWGLFLALGLGMSAPWLLVAIRPGLALRLPRPGRWMNVLRRIL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHH
GLMMLGSAIWLATLLLPHFGFTASKSAQDTAQWQPLSEQAIQSALAQHKRVFVDVTADWC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCEEEEEEECCEE
ITCKVNKYNVLQKEDVQAALQQPDVVALRGDWTLPSDAITDFLKTRGQVAVPFNQVYGPG
EEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEECHHHHCCCC
LPEGEALPTLLTRDAVLQTLKKAKGITQ
CCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA