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The map label for this gene is ndh [H]

Identifier: 29142143

GI number: 29142143

Start: 1775760

End: 1777064

Strand: Reverse

Name: ndh [H]

Synonym: t1709

Alternate gene names: 29142143

Gene position: 1777064-1775760 (Counterclockwise)

Preceding gene: 29142144

Following gene: 29142142

Centisome position: 37.08

GC content: 54.48

Gene sequence:

>1305_bases
TTGACTACACCATTAAAAAAGATCGTGATTGTCGGCGGCGGCGCTGGCGGGCTGGAAATGGCGACGCAGTTAGGCCATAA
ACTGGGGCGCAAGAAAAAAGCGAAAATCACGCTGGTAGACAGAAATCACAGCCATCTGTGGAAACCATTGCTGCACGAAG
TGGCGACTGGCTCTCTGGACGAAGGCGTGGATGCGCTGAGCTATCTGGCTCATGCGCGTAATCATGGTTTCCAGTTCCAG
CTGGGGTCGGTGATGGATATCGATCGCGAAGCGAAGACCATCACCATTGCCGAGTTGCGTGATGAAAAGGGCGAACTGCT
GGTGCCGGAGCGCAAAATCGCGTATGACACGCTGGTGATGGCGCTGGGCAGCACCTCTAATGATTTCAACACGCCGGGCG
TGAAAGAGCACTGTATCTTCCTCGATAACCCGCATCAGGCGCGCCGTTTTCACCAGGAGATGCTGAACCTGTTCCTCAAG
TATTCGGCTAACCTGGGCGCGAACGGTAAGGTCAATATCGCCATCGTTGGCGGCGGTGCGACGGGGGTTGAGCTGTCGGC
TGAACTGCATAATGCGGTAAAACAGCTGCATAGCTATGGTTATAAGGGGCTGACCAACGACGCGTTGAACGTGACGTTGG
TTGAGGCTGGCGAGCGTATTCTGCCTGCGTTGCCGCCGCGTATCTCCAGCGCCGCGCATAATGAACTGACCAAACTGGGC
GTTCGCGTACTGACGCAAACTATGGTCACCAGCGCCGACGAAGGCGGTCTGCATACGAAAGAAGGTGAATATATTCAGGC
CGATCTGATGGTGTGGGCGGCGGGTATCAAAGCGCCAGATTTTATGAAAGAAATTGGTGGTCTGGAAACGAACCGCATTA
ACCAACTGGTGGTGGAACCGACGCTGCAAACCACGCGTGATCCTGATATTTATGCGATTGGCGACTGCGCTTCCTGCGCA
CGTCCGGAGGGAGGTTTTGTGCCGCCTCGCGCTCAGGCGGCGCATCAGATGGCTACCTGCGCGATGAATAACATTCTGGC
GCAGATGAATGGCAAGCCGCTGAAAGCTTACCAGTATAAAGATCATGGATCGCTGGTCTCTCTGTCCAACTTCTCTACCG
TGGGTAGTCTGATGGGGAACCTGACCCGCGGTTCAATGATGATTGAAGGACGTATCGCCCGCTTCGTGTATATCTCGCTA
TACCGTATGCACCAGATAGCGCTGCATGGATACTTTAAAACCGGCCTGATGATGCTGGTGGGCAGTATTAACCGCGTCAT
TCGTCCGCGCCTGAAACTGCATTAA

Upstream 100 bases:

>100_bases
ATATCAGAAGCTTATTCTCATTAACGTAACTTGTTGTTAATTAAAGGCTATACTAATAACTTTTAATTAACAATTGGTTA
ATAAATTTAAGGGGGTCACG

Downstream 100 bases:

>100_bases
TTTTTCTGCGCCTCACCGGCTGCTCGCCGGTGAGCGCTTCTCCATCACTTGCTTCGGAGTTGTCCGAATCCTTCAGCTTT
ACCGCCTCATCCCGCATTTT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQ
LGSVMDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKEHCIFLDNPHQARRFHQEMLNLFLK
YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNDALNVTLVEAGERILPALPPRISSAAHNELTKLG
VRVLTQTMVTSADEGGLHTKEGEYIQADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCA
RPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKAYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISL
YRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH

Sequences:

>Translated_434_residues
MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQ
LGSVMDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKEHCIFLDNPHQARRFHQEMLNLFLK
YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNDALNVTLVEAGERILPALPPRISSAAHNELTKLG
VRVLTQTMVTSADEGGLHTKEGEYIQADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCA
RPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKAYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISL
YRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH
>Mature_433_residues
TTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQL
GSVMDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKEHCIFLDNPHQARRFHQEMLNLFLKY
SANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNDALNVTLVEAGERILPALPPRISSAAHNELTKLGV
RVLTQTMVTSADEGGLHTKEGEYIQADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCAR
PEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKAYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISLY
RMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=434, Percent_Identity=97.6958525345622, Blast_Score=865, Evalue=0.0,
Organism=Escherichia coli, GI1789065, Length=358, Percent_Identity=25.9776536312849, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323515, Length=464, Percent_Identity=25.8620689655172, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320118, Length=349, Percent_Identity=25.5014326647564, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323794, Length=355, Percent_Identity=27.887323943662, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47379; Mature: 47247

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLD
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHH
EGVDALSYLAHARNHGFQFQLGSVMDIDREAKTITIAELRDEKGELLVPERKIAYDTLVM
HHHHHHHHHHHHHCCCCEEECCCEECCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHH
ALGSTSNDFNTPGVKEHCIFLDNPHQARRFHQEMLNLFLKYSANLGANGKVNIAIVGGGA
HHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCC
TGVELSAELHNAVKQLHSYGYKGLTNDALNVTLVEAGERILPALPPRISSAAHNELTKLG
CCEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHH
VRVLTQTMVTSADEGGLHTKEGEYIQADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEP
HHHHHHHHHHCCCCCCCCCCCCCEEEEEHEEEECCCCCHHHHHHHCCCCCCCCCEEEECC
TLQTTRDPDIYAIGDCASCARPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKAYQYK
CHHCCCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISLYRMHQIALHGYFKTGLMMLV
CCCCEEEECCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSINRVIRPRLKLH
HHHHHHHCCHHCCC
>Mature Secondary Structure 
TTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLD
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHH
EGVDALSYLAHARNHGFQFQLGSVMDIDREAKTITIAELRDEKGELLVPERKIAYDTLVM
HHHHHHHHHHHHHCCCCEEECCCEECCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHH
ALGSTSNDFNTPGVKEHCIFLDNPHQARRFHQEMLNLFLKYSANLGANGKVNIAIVGGGA
HHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCC
TGVELSAELHNAVKQLHSYGYKGLTNDALNVTLVEAGERILPALPPRISSAAHNELTKLG
CCEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHH
VRVLTQTMVTSADEGGLHTKEGEYIQADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEP
HHHHHHHHHHCCCCCCCCCCCCCEEEEEHEEEECCCCCHHHHHHHCCCCCCCCCEEEECC
TLQTTRDPDIYAIGDCASCARPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKAYQYK
CHHCCCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISLYRMHQIALHGYFKTGLMMLV
CCCCEEEECCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSINRVIRPRLKLH
HHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]