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The map label for this gene is mppA [H]

Identifier: 29142023

GI number: 29142023

Start: 1642675

End: 1644288

Strand: Reverse

Name: mppA [H]

Synonym: t1583

Alternate gene names: 29142023

Gene position: 1644288-1642675 (Counterclockwise)

Preceding gene: 29142025

Following gene: 29142021

Centisome position: 34.31

GC content: 48.95

Gene sequence:

>1614_bases
ATGAGGCATTCTGTTTCAGTAACCTGTTGTGCGCTGTTGGTTAGCAGCTTTTCCCTGGCATATGCTGCGGATGTTCCCGG
CGGAACGGTACTGGCAGAGAAACAAGAACTGGTGCGTCATATCAAAGATGAGCCCGCTTCGTTAGATCCAGCGAAAGCCG
TTGGGCTGCCTGAAATTCAGGTGATCCGCGATCTGTTTGAAGGGCTGGTTAACCAGAACGAAAAGGGTGAAATTATCCCT
GGCGTCGCCAGCCAGTGGAAGAGCAATGATAATCGTATCTGGACGTTTACGTTGCGGGATGATGCGCAATGGGCCGATGG
AACGCCGGTGACCGCCCAGGATTTTGTCTATAGCTGGCAACGCCTCGTTGATCCCAAAACGCTTTCCCCCTTCGCCTGGT
TTGCCGCTCTGGCTGGCATCACTAATGCGCAAGCCATTATCGACAGTAAAGTCACGCCGGATCAGCTTGGCGTCAGTGCC
GTGGACGCGCACACTTTGCGTGTTCAGCTTGACAAGCCGTTGCCCTGGTTTGCCAGTCTGACCGCCAGTTTTGCCTTTTA
TCCGGTCCAAAAAGCGAATGTCGAAAGCGGCAAAGACTGGATGAAGCCGGGAAAACTGATTGGCAATGGCGCGTATGTGC
TTAAAGAGCGCGTGGTAAATGAAAAACTGGTGGTCGTGCCTAATACGCATTACTGGGATAACGCGAAAACGGTACTGCAA
AAAGTGACATTTTTACCCATTAACCAGGAGTCGGCTGCGACGAAACGCTATCTTGCCGGTGATATTGATATCACCGAATC
TTTCCCTAAAAATATGTACCAGAAATTATTGAAGGATATTCCAGGGCAAGTTTATACGCCGCCGCAATTAGGGACTTATT
ATTATGCGTTTAATACGCAGAAAGGGCCGACGGCGGATTCCCGCGTTCGTCTGGCGCTAAGTATGACCATTGATCGCCGT
TTGATGGCGGAAAAAGTCTTAGGTACCGGTGAAAAACCGGCCTGGCATTTTACACCGGATGTCACGGCAGGATTTAAGCC
CGATCCTTCACCGTTTGAACAAATGAGTCAGGAAGAACTTAACGCCCAGGCGAAAACATTGCTGCGTGCAGCAGGCTACG
GATCGCAGAAGCCGCTTAAATTAACTCTGCTTTACAATACCTCAGAAAACCATCAGAAAATCGCGATTGCGGTGGCGTCA
ATGTGGAAGAAAAATCTGGGGGTGGATGTGAAATTGCAAAACCAGGAGTGGAAAACGTATATCGACAGCCGGAATACCAG
TAATTTTGATGTTATTCGCGTCTCCTGGGTGGGTGATTACAACGAACCGTCGACTTTCTTATCCTTATTAACGTCCACGC
ATACGGGGAATATTTCACGCTTTACTAATCCGACTTATGACAAAATCCTGACGCAAGCGACGATGGAAAATACCGCCGAA
GCGCGTAACGCGGATTACAATGCAGCGGAGAAAATTTTAACGGAACAAGCGCCTATAGCACCTATTTATCAGTATACCAA
TGGCCGGTTAATTAAACCGTGGGTAAAGGGATACCCCATTACTAACCCGGAAGATGTGGCCTATAGCCGTACAATGTATA
TCGTGAAGCACTGA

Upstream 100 bases:

>100_bases
TGTATGGCGCGATATCAACTTTCTGGCGGAAGATAATTGCATTTCTTTCTGCTGAAACAAATAATTACGTTGTCATTTAA
CTCATCTTTGAGGAACTTCT

Downstream 100 bases:

>100_bases
TGCGTACTGGTTTCTTGTTAACTCAAGGTAGCCACGCCCGCCGCCTGATGCTGGCAGAAGGCATGGGGATTAAGCGAGCG
CCTGATGCCGCCGTTCTCAT

Product: periplasmic murein peptide-binding protein MppA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDSKVTPDQLGVSA
VDAHTLRVQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTSNFDVIRVSWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH

Sequences:

>Translated_537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDSKVTPDQLGVSA
VDAHTLRVQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTSNFDVIRVSWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
>Mature_537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDSKVTPDQLGVSA
VDAHTLRVQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTSNFDVIRVSWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=91.9925512104283, Blast_Score=1041, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=539, Percent_Identity=48.0519480519481, Blast_Score=500, Evalue=1e-143,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=42.7221172022684, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1787762, Length=541, Percent_Identity=28.2809611829945, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789887, Length=483, Percent_Identity=24.0165631469979, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789966, Length=466, Percent_Identity=22.3175965665236, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59993; Mature: 59993

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIIPGVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGITNAQAIIDSKVTPDQLGVSAVDAHTLRVQLDKPLPWFASL
HHCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCHHHCCCEEECCEEEEEEECCCCCHHHHH
TASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
HHHHEEEECCCCCCCCCHHHCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
HHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADSRVRLALSMTIDRRLMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEEL
CCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTSNFDVIRVSWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
HCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
HCCCCCHHHHHHHHCCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIIPGVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGITNAQAIIDSKVTPDQLGVSAVDAHTLRVQLDKPLPWFASL
HHCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCHHHCCCEEECCEEEEEEECCCCCHHHHH
TASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
HHHHEEEECCCCCCCCCHHHCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
HHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADSRVRLALSMTIDRRLMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEEL
CCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTSNFDVIRVSWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
HCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
HCCCCCHHHHHHHHCCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]